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Thinking and error
Anne-Maree Kelly
December 5, 2012
Permissions
 This presentation may be reproduced in full or in part
on the condition that each slide used carries the
following:
‘Reproduced with the permission of Professor Anne-
Maree Kelly, Joseph Epstein Centre for Emergency
Medicine Research @Western Health, Melbourne,
Australia’.
@kellyam_jec
Diagnostic error
 Common
 A top cause of medicolegal actions
 Up to 20% of autopsies
 Emergency Medicine is a high risk environment
 Why?
Diagnostic error
 “No fault’ error
 Silent or atypical disease
 Mimics something more common
 Lack of patient co-operation or presentation of symptoms
 Limitation of medical knowledge
 Systems error
 Technical: test error, lack of test/resource
 Organisational: supervision, unavailability of expertise,
inefficient processes, cultural issues
 Cognitive error
 Faulty data collection or interpretation
 Flawed reasoning
 Incomplete knowledge
Cognitive error: My questions
 Is it predictable?
 Is it unavoidable?
Your experience
 Work with the two or three people around you.
 Can you identify a case that you were involved in or
heard about where thinking processes contributed to
a diagnostic error?
Cases from the medicolegal world
 Ms X aged 42
 Single mother of 4
 Abdominal pain and vomiting
 Exam difficult due to obesity
 Three presentations to ED of a tertiary referral hospital
over 5 days
 Diagnosis #1: gastro (xray and bloods performed)
 Diagnosis #2: gastro; no further tests
 Diagnosis #3: bowel obstruction, ARF, gangrenous gut
 Outcome: death
The issues
 #1:
 Assessment was reasonable
 Xray was performed and clearly showed small bowel
obstruction
 #2:
 Assessment was brief
 Assumed that previous diagnosis was correct
 Did not check results/ xray
The cost
 4 children under 15 without a mother (or interested
father)
 > 1 million dollars settlement
Case 2
 HG aged 3
 Rural setting, experienced mum
 24 hours of D&V
 Seen by GP 1: gastro, home for fluids
 Seen by GP 2 next day: gastro; home for fluids
 Presented in ED in next town: gastro; home for fluids
 Day 3 admitted to small rural hospital by GP registrar for oral fluids.
Mother concerned re lack of urine.
 Day 4 evident that there had been no urine output for ~24 hours
 IV therapy
 Transferred to large hospital on Day 5
 Cardiac arrest, died
The issues
 First GP assessment fine
 Second GP assessment
 Failure of data collection: weight
 Assumption that all gastro settles with oral fluids
 Not listening to mum re intake / output
 ED assessment
 Failure of data collection: weight
 Assumption that all gastro settles with oral fluids
 Not listening to mum re intake / output
 In hospital management
 Failure of data collection: weight, fluid balance chart, frequent obs
 Assumption that all gastro settles with oral fluids
 Not listening to mum re intake / output
 ‘It will all be alright’ mentality blocking escalation of care to
specialist centre
Something closer to home
 30-something woman
 Sore throat 24-48 hours
 Unable to swallow saliva
 Epiglottis suspected by ED team
 Difficulty engaging ENT team
 Eventually came and attempted endoscopic exam
 Acute hypoxia
 Surgical airway
 Alive...but close run thing
Issues
 Epiglottis now very uncommon
 Dismissed the likelihood despite reasonable evidence
 Failure to respect assessment of clinician actually
seeing the patient
Types of cognitive predispositions to respond
Type of CDR Explanation
Aggregate bias Failure to believe aggregate data, eg guidelines
‘My patient is different’
Anchoring Locking on to features in presentation too early and
failing to adjust with further data
Ascertainment bias Thinking shaped by prior expectation eg gender
bias, stereotyping
Availability Diagnosis is more likely if it readily comes to mind
Base-rate neglect Tendency to ignore the true prevalence of a
disease, impacts Bayesian thinking
Commission bias Belief that harm can only be prevented by action;
tendency to action rather than inaction
Confirmation bias The tendency to look for confirming evidence rather
than evidence to refute
Diagnosis momentum Diagnoses are like sticky labels; once attached hard
to remove
Types of cognitive predispositions to respond
Type of CDR Explanation
Feedback sanction Error not temporarily associated with immediate
consequences
Framing effect The way we see things is influenced by how they are
presented to us (gastro and positive stool for blood
story)
Fundamental attribution error Blame patients for illness rather than look at situational
factors
Gambler’s fallacy Pretest probability of a particular diagnosis influenced
by previous but independent events (eg coin toss
example)
Gender bias False belief of difference in probability of a diagnosis
between genders
Hindsight bias Knowing what happened influences the perception of
past events and inhibits realistic appraisal of why error
occurred
Types of cognitive predispositions to respond
Type of CDR Explanation
Multiple alternatives bias Multiple options cause uncertainty; tendency to limit
options to those we know and potentially ignore rarer
alternatives
Omission bias Tendency towards inaction, usually for fear of doing
harm
Order effects Information transfer is U shaped; we ‘hear’ better at the
beginning and end. May miss important stuff in the
middle
Outcome bias The tendency to opt for diagnoses with good outcomes
Over-confidence bias Belief that we know more than we do!
Playing the odds In ambiguous situations, a tendency to opt for the less
serious diagnosis
Posterior probability error The tendency to be unduly influenced by what has
gone on before (see case 1)
Types of cognitive predispositions to respond
Type of CDR Explanation
Premature closure Very powerful: Tendency to accept a diagnosis before it
is fully verified
Psych-out error Tendency for error in psych patients especially missing
of serious medical issues
Representativeness restraint Looks like a duck, quacks like a duck, is a duck
Missing atypical presentations
Search satisfying Inappropriately calling off the search once something
has been found
Sunk costs The more we ‘invest’ in a diagnosis, the less likely we
are to relese it
Sutton’s slip Going for the obvious
Triage cueing Triage assignment falsely prompts bias towards
serious/ non-serious illness
Unpacking principle Failure to elicit all relevant information
Types of cognitive predispositions to respond
Type of CDR Explanation
Vertical line failure Thinking in silos; inflexible thinking; failure to consider
what else might this be?
Visceral bias Visceral arousal is associated with poor decisions
Feelings towards patients (positive and negative) may
result in diagnoses being missed
Our pre-disposition to CDR depends on:
•Personality
•Experience
•Self-awareness
•Environment/ situation
Avoiding cognitive error: Exercise
 Group 1:
 In pairs or threes,
describe strategies that
might help clinicians
avoid CDR in patients
they manage
 Group 2:
 In pairs or threes,
describe strategies that
might help supervising
clinicians/ consultants
avoid CDR in cases
they are consulted
about
Cognitive de-biasing strategies
Strategy Mechanism/ Action
Develop insight/ awareness Talking about and analysing diagnostic errors
Sharing experience
Consider alternatives Establish processes that ‘force’ consideration of
other diagnoses
Routinely asking What else might this be?
Documenting why you consider something unlikely
and why
Develop reflective approach to
problem solving
Regularly ask yourself how you are thinking about
diagnostic problems and how you might do it better
Decrease reliance on memory System level: cognitive aids, guidelines, etc
Personal level: Don’t rely on memory. Look things
up!
Specific training In CDR
In probability theory and Bayesian thinking
Simulation Both as case discussion and in simulator training
Cognitive de-biasing strategies
Strategy Mechanism/ Action
Cognitive forcing strategies Develop specific strategies for particular high risk
situations eg medical clearance of psychiatric
patients
Make it easier More information readily available
Minimise time pressures More time to think usually means better decisions
Accountability Clear accountability and followup of decisions
made
Feedback Rapid and reliable feedback esp. re diagnostic error
or ‘good picks’ assists diagnostic ‘calibration’
Teamwork Two heads are better than one. Information
sharing/consultation with other team members eg
nurses, other doctors, allied health etc.
Summary
 Diagnostic error and how we think are intimated
associated
 Cognitive errors can be reduced by:
 System measures to promote information availability and
‘force’ consideration of high risk groups/ diagnoses
 Personal measures such as self-awareness, de-biasing
strategies
 Training
 Teamwork

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Thinking and error in emergency departments

  • 1. Thinking and error Anne-Maree Kelly December 5, 2012
  • 2. Permissions  This presentation may be reproduced in full or in part on the condition that each slide used carries the following: ‘Reproduced with the permission of Professor Anne- Maree Kelly, Joseph Epstein Centre for Emergency Medicine Research @Western Health, Melbourne, Australia’. @kellyam_jec
  • 3. Diagnostic error  Common  A top cause of medicolegal actions  Up to 20% of autopsies  Emergency Medicine is a high risk environment  Why?
  • 4. Diagnostic error  “No fault’ error  Silent or atypical disease  Mimics something more common  Lack of patient co-operation or presentation of symptoms  Limitation of medical knowledge  Systems error  Technical: test error, lack of test/resource  Organisational: supervision, unavailability of expertise, inefficient processes, cultural issues  Cognitive error  Faulty data collection or interpretation  Flawed reasoning  Incomplete knowledge
  • 5. Cognitive error: My questions  Is it predictable?  Is it unavoidable?
  • 6. Your experience  Work with the two or three people around you.  Can you identify a case that you were involved in or heard about where thinking processes contributed to a diagnostic error?
  • 7. Cases from the medicolegal world  Ms X aged 42  Single mother of 4  Abdominal pain and vomiting  Exam difficult due to obesity  Three presentations to ED of a tertiary referral hospital over 5 days  Diagnosis #1: gastro (xray and bloods performed)  Diagnosis #2: gastro; no further tests  Diagnosis #3: bowel obstruction, ARF, gangrenous gut  Outcome: death
  • 8. The issues  #1:  Assessment was reasonable  Xray was performed and clearly showed small bowel obstruction  #2:  Assessment was brief  Assumed that previous diagnosis was correct  Did not check results/ xray
  • 9. The cost  4 children under 15 without a mother (or interested father)  > 1 million dollars settlement
  • 10. Case 2  HG aged 3  Rural setting, experienced mum  24 hours of D&V  Seen by GP 1: gastro, home for fluids  Seen by GP 2 next day: gastro; home for fluids  Presented in ED in next town: gastro; home for fluids  Day 3 admitted to small rural hospital by GP registrar for oral fluids. Mother concerned re lack of urine.  Day 4 evident that there had been no urine output for ~24 hours  IV therapy  Transferred to large hospital on Day 5  Cardiac arrest, died
  • 11. The issues  First GP assessment fine  Second GP assessment  Failure of data collection: weight  Assumption that all gastro settles with oral fluids  Not listening to mum re intake / output  ED assessment  Failure of data collection: weight  Assumption that all gastro settles with oral fluids  Not listening to mum re intake / output  In hospital management  Failure of data collection: weight, fluid balance chart, frequent obs  Assumption that all gastro settles with oral fluids  Not listening to mum re intake / output  ‘It will all be alright’ mentality blocking escalation of care to specialist centre
  • 12. Something closer to home  30-something woman  Sore throat 24-48 hours  Unable to swallow saliva  Epiglottis suspected by ED team  Difficulty engaging ENT team  Eventually came and attempted endoscopic exam  Acute hypoxia  Surgical airway  Alive...but close run thing
  • 13. Issues  Epiglottis now very uncommon  Dismissed the likelihood despite reasonable evidence  Failure to respect assessment of clinician actually seeing the patient
  • 14. Types of cognitive predispositions to respond Type of CDR Explanation Aggregate bias Failure to believe aggregate data, eg guidelines ‘My patient is different’ Anchoring Locking on to features in presentation too early and failing to adjust with further data Ascertainment bias Thinking shaped by prior expectation eg gender bias, stereotyping Availability Diagnosis is more likely if it readily comes to mind Base-rate neglect Tendency to ignore the true prevalence of a disease, impacts Bayesian thinking Commission bias Belief that harm can only be prevented by action; tendency to action rather than inaction Confirmation bias The tendency to look for confirming evidence rather than evidence to refute Diagnosis momentum Diagnoses are like sticky labels; once attached hard to remove
  • 15. Types of cognitive predispositions to respond Type of CDR Explanation Feedback sanction Error not temporarily associated with immediate consequences Framing effect The way we see things is influenced by how they are presented to us (gastro and positive stool for blood story) Fundamental attribution error Blame patients for illness rather than look at situational factors Gambler’s fallacy Pretest probability of a particular diagnosis influenced by previous but independent events (eg coin toss example) Gender bias False belief of difference in probability of a diagnosis between genders Hindsight bias Knowing what happened influences the perception of past events and inhibits realistic appraisal of why error occurred
  • 16. Types of cognitive predispositions to respond Type of CDR Explanation Multiple alternatives bias Multiple options cause uncertainty; tendency to limit options to those we know and potentially ignore rarer alternatives Omission bias Tendency towards inaction, usually for fear of doing harm Order effects Information transfer is U shaped; we ‘hear’ better at the beginning and end. May miss important stuff in the middle Outcome bias The tendency to opt for diagnoses with good outcomes Over-confidence bias Belief that we know more than we do! Playing the odds In ambiguous situations, a tendency to opt for the less serious diagnosis Posterior probability error The tendency to be unduly influenced by what has gone on before (see case 1)
  • 17. Types of cognitive predispositions to respond Type of CDR Explanation Premature closure Very powerful: Tendency to accept a diagnosis before it is fully verified Psych-out error Tendency for error in psych patients especially missing of serious medical issues Representativeness restraint Looks like a duck, quacks like a duck, is a duck Missing atypical presentations Search satisfying Inappropriately calling off the search once something has been found Sunk costs The more we ‘invest’ in a diagnosis, the less likely we are to relese it Sutton’s slip Going for the obvious Triage cueing Triage assignment falsely prompts bias towards serious/ non-serious illness Unpacking principle Failure to elicit all relevant information
  • 18. Types of cognitive predispositions to respond Type of CDR Explanation Vertical line failure Thinking in silos; inflexible thinking; failure to consider what else might this be? Visceral bias Visceral arousal is associated with poor decisions Feelings towards patients (positive and negative) may result in diagnoses being missed Our pre-disposition to CDR depends on: •Personality •Experience •Self-awareness •Environment/ situation
  • 19. Avoiding cognitive error: Exercise  Group 1:  In pairs or threes, describe strategies that might help clinicians avoid CDR in patients they manage  Group 2:  In pairs or threes, describe strategies that might help supervising clinicians/ consultants avoid CDR in cases they are consulted about
  • 20. Cognitive de-biasing strategies Strategy Mechanism/ Action Develop insight/ awareness Talking about and analysing diagnostic errors Sharing experience Consider alternatives Establish processes that ‘force’ consideration of other diagnoses Routinely asking What else might this be? Documenting why you consider something unlikely and why Develop reflective approach to problem solving Regularly ask yourself how you are thinking about diagnostic problems and how you might do it better Decrease reliance on memory System level: cognitive aids, guidelines, etc Personal level: Don’t rely on memory. Look things up! Specific training In CDR In probability theory and Bayesian thinking Simulation Both as case discussion and in simulator training
  • 21. Cognitive de-biasing strategies Strategy Mechanism/ Action Cognitive forcing strategies Develop specific strategies for particular high risk situations eg medical clearance of psychiatric patients Make it easier More information readily available Minimise time pressures More time to think usually means better decisions Accountability Clear accountability and followup of decisions made Feedback Rapid and reliable feedback esp. re diagnostic error or ‘good picks’ assists diagnostic ‘calibration’ Teamwork Two heads are better than one. Information sharing/consultation with other team members eg nurses, other doctors, allied health etc.
  • 22. Summary  Diagnostic error and how we think are intimated associated  Cognitive errors can be reduced by:  System measures to promote information availability and ‘force’ consideration of high risk groups/ diagnoses  Personal measures such as self-awareness, de-biasing strategies  Training  Teamwork