SlideShare une entreprise Scribd logo

Breast carcinoma pathology

•Télécharger en tant que PPT, PDF•
•
Kripa Vijay
Kripa Vijay

Useful for students of pathology

Santé & Médecine
1  sur  59
Dr. P. Karpagam Kiruba Rajeswari, M.B.B.S.,D.C.P., Tutor in Pathology, MAPIMS
[object Object]
BREAST CARCINOMA – RISK FACTORS
 
 
 
PATHOGNESIS – GENETIC FACTORS ,[object Object]
BRCA -1  Breast Cancer 1,Early onset ( Chr.17) BRCA-2, Breast Cancer 2,Early onset( Chr.13) p53( Chr.17) CHEK2( Chr. 22) ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Germline point mutations/Deletions of BRCA1 gene  Hereditary breast & ovarian cancers. Mutations  20% Hereditary breast cancer, ovarian cancer, increased cancer risk in male carriers. Mutations  Sporadic breast cancers.  Li fraumeni syndrome Mutations - rare (<5%). Li fraumeni variant Increase breast cancer risk after radiation exposure
HER2/neu ,[object Object],[object Object],[object Object],[object Object],[object Object]
PATHOGENESIS – HORMONAL FACTORS ,[object Object],[object Object],[object Object],[object Object],[object Object]
ESTROGEN DEPENDENT TUMOURS ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object]
 
CLASSIFICATION – BREAST CARCINOMA ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object]
DUCTAL CARCINOMA IN SITU ,[object Object],[object Object],[object Object]
 
Comedocarcinoma ,[object Object],[object Object],[object Object],[object Object],[object Object]
Noncomedo DCIS ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Noncomedo DCIS ,[object Object],[object Object],[object Object],[object Object],[object Object]
PAGET’S DISEASE OF NIPPLE ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
PAGET’S DISEASE OF NIPPLE
DCIS WITH MICROINVASION ,[object Object],[object Object],[object Object]
MANAGEMENT AND PROGNOSIS OF DCIS ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
LOBULAR CARCINOMA IN SITU ,[object Object],[object Object],[object Object],[object Object]
LOBULAR CARCINOMA IN SITU - MORPHOLOGY ,[object Object],[object Object],[object Object],[object Object]
LOBULAR CARCINOMA IN SITU ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
 
INVASIVE CARCINOMA – CLINICALFEATURES ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Invasive Carcinoma, No Special Type (NST; Invasive Ductal Carcinoma) ,[object Object],[object Object],[object Object]
Invasive Carcinoma – NST- HPE Features Well diff. Ca Mod. diff.Ca Poorly diff. Ca. Tubule formation Prominent Less,solid clusters/single infiltrating cells Ragged nests/solid sheets of cells Nuclei Small,round,monomorphic Greater nuclear pleomorphism Nuclei – enlarged,irregular. Mitotic figures Rare Present Numerous Proliferation rate - - High Tumour necrosis - - Present
INVASIVE LOBULAR CARCINOMA ,[object Object],[object Object],[object Object]
INVASIVE LOBULAR CARCINOMA ,[object Object],[object Object],[object Object],[object Object]
INVASIVE LOBULAR CARCINOMA ,[object Object],[object Object],[object Object]
MEDULLARY CARCINOMA ,[object Object],[object Object],[object Object]
MEDULLARY CARCINOMA - HPE ,[object Object],[object Object],[object Object],[object Object],[object Object]
MEDULLARY CARCINOMA ,[object Object],[object Object],[object Object]
MUCINOUS/COLLOID CARCINOMA ,[object Object],[object Object]
MUCINOUS CARCINOMA - HPE ,[object Object],[object Object],[object Object],[object Object]
TUBULAR CARCINOMA ,[object Object],[object Object],[object Object],[object Object],[object Object]
INVASIVE PAPILLARY & MICROPAPILLARY CARCINOMA ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
INFLAMMATORY CARCINOMA ,[object Object],[object Object],[object Object],[object Object]
METAPLASTIC CARCINOMA ,[object Object],[object Object],[object Object],[object Object]
PROGNOSTIC FACTORS - MAJOR ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Stage T: Primary Cancer Lymph Nodes (LNs) M: Distant Metastasis 5-Year Survival (%) 0 DCIS or LCIS No metastases Absent 92 I Invasive carcinoma ≤2 cm No metastases Absent 87 II Invasive carcinoma >2 cm No metastases Absent 75 Invasive carcinoma <5 cm 1 to 3 positive LNs Absent III Invasive carcinoma >5 cm 1 to 3 positive LNs Absent 46 Any size invasive carcinoma ≥ 4 positive LNs Absent Invasive carcinoma with skin or chest wall involvement or inflammatory carcinoma 0 to >10 positive LNs. Absent IV Any size invasive carcinoma Negative or positive lymph nodes Present 13
PROGNOSTIC FACTORS - MINOR
 
 
 
 
FIBROADENOMA ,[object Object],[object Object],[object Object],[object Object],[object Object],GROSS: Spherical, sharply circumscribed, rubbery, grayish white, freely movable nodules -bulge above the surrounding tissue and contain slitlike spaces. < 1 cm – large tumors.
FIBROADENOMA - HPE ,[object Object],[object Object],[object Object]
FIBROADENOMA - TYPES ,[object Object],[object Object],In  pericanalicular  histologic pattern, the  glands maintain their round or oval profiles.  There is  no prognostic or clinical significance  attached to the pericanalicular and intracanalicular patterns. Both may be seen within the same lesion. 
PHYLLODES TUMOUR  Phyllodes – leaf-like ,[object Object],[object Object],[object Object],[object Object],[object Object]
PHYLLODES TUMOUR ,[object Object],[object Object],[object Object],[object Object],[object Object]
 
NORMAL MALE BREAST ,[object Object]
GYNAECOMASTIA ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
 

Recommandé

Paraneoplastic syndromes
Paraneoplastic syndromesParaneoplastic syndromes
Paraneoplastic syndromesSCGH ED CME
 
Breast carcinoma
Breast carcinoma Breast carcinoma
Breast carcinoma Dr Praveen kumar tripathi
 
Non hodgkins lymphoma
Non hodgkins lymphomaNon hodgkins lymphoma
Non hodgkins lymphomaChandan N
 
Seminoma
SeminomaSeminoma
SeminomaVenkatesan Amirthalingam
 
Lung Cancer Pathology & Clinical
Lung Cancer Pathology & Clinical Lung Cancer Pathology & Clinical
Lung Cancer Pathology & Clinical Shahd Al Ali
 
Ovarian teratoma
Ovarian teratomaOvarian teratoma
Ovarian teratomaUma Chidiebere
 
Fibroadenoma
FibroadenomaFibroadenoma
FibroadenomaAbino David
 
testicular tumors
testicular tumorstesticular tumors
testicular tumorsDrAyush Garg
 

Recommandé

Paraneoplastic syndromes
Paraneoplastic syndromesParaneoplastic syndromes
Paraneoplastic syndromesSCGH ED CME
 
Breast carcinoma
Breast carcinoma Breast carcinoma
Breast carcinoma Dr Praveen kumar tripathi
 
Non hodgkins lymphoma
Non hodgkins lymphomaNon hodgkins lymphoma
Non hodgkins lymphomaChandan N
 
Seminoma
SeminomaSeminoma
SeminomaVenkatesan Amirthalingam
 
Lung Cancer Pathology & Clinical
Lung Cancer Pathology & Clinical Lung Cancer Pathology & Clinical
Lung Cancer Pathology & Clinical Shahd Al Ali
 
Ovarian teratoma
Ovarian teratomaOvarian teratoma
Ovarian teratomaUma Chidiebere
 
Fibroadenoma
FibroadenomaFibroadenoma
FibroadenomaAbino David
 
testicular tumors
testicular tumorstesticular tumors
testicular tumorsDrAyush Garg
 
Paget disease of the breast
Paget disease of the breastPaget disease of the breast
Paget disease of the breastBashir BnYunus
 
Pathology of Breast Disorders
Pathology of Breast DisordersPathology of Breast Disorders
Pathology of Breast DisordersShashidhar Venkatesh Murthy
 
Breast pathology 1
Breast pathology 1Breast pathology 1
Breast pathology 1Prasad CSBR
 
CARCINOMA PENIS
CARCINOMA PENISCARCINOMA PENIS
CARCINOMA PENISVikas Kumar
 
OVARIAN TUMOURS
OVARIAN TUMOURSOVARIAN TUMOURS
OVARIAN TUMOURSNiranjan Chavan
 
Colorectal Cancer
Colorectal CancerColorectal Cancer
Colorectal CancerSuneet Khurana
 
Testicular tumors
Testicular tumorsTesticular tumors
Testicular tumorsNarmada Tiwari
 
Benign breast disease
Benign breast diseaseBenign breast disease
Benign breast diseaseJyotindra Singh
 
Prognostic factors in carcinoma breast ppt
Prognostic factors in carcinoma breast pptPrognostic factors in carcinoma breast ppt
Prognostic factors in carcinoma breast pptSwati Wadhai
 
ANDI & benign breast disorders
ANDI & benign breast disordersANDI & benign breast disorders
ANDI & benign breast disordersdileep hoysal
 
Testicular tumours
Testicular tumoursTesticular tumours
Testicular tumoursShubham Lavania
 
Gastric Cancer - Pathology Seminar
Gastric Cancer - Pathology SeminarGastric Cancer - Pathology Seminar
Gastric Cancer - Pathology SeminarDr. Pritika Nehra
 
PROGNOSTIC AND PREDICTIVE FACTORS FOR METASTATIC CARCINOMA BREAST
PROGNOSTIC AND PREDICTIVE FACTORS FOR METASTATIC CARCINOMA BREASTPROGNOSTIC AND PREDICTIVE FACTORS FOR METASTATIC CARCINOMA BREAST
PROGNOSTIC AND PREDICTIVE FACTORS FOR METASTATIC CARCINOMA BREASTDrAnkitaPatel
 
Renal cell carcinoma
Renal cell carcinomaRenal cell carcinoma
Renal cell carcinomaArkaprovo Roy
 
Tumor markers
Tumor markersTumor markers
Tumor markersnishma bajracharya
 
Benign and Malignant Breast Diseases
Benign and Malignant Breast DiseasesBenign and Malignant Breast Diseases
Benign and Malignant Breast Diseasesyuyuricci
 
Thyroid neoplasms
Thyroid neoplasmsThyroid neoplasms
Thyroid neoplasmsJibran Mohsin
 
Teratoma
TeratomaTeratoma
Teratomamo mo
 
Soft tissue sarcoma
Soft tissue sarcomaSoft tissue sarcoma
Soft tissue sarcomaimrana tanvir
 
Carcinoma rectum (Rectal Cancer)
Carcinoma rectum (Rectal Cancer)Carcinoma rectum (Rectal Cancer)
Carcinoma rectum (Rectal Cancer)Dr Vandana Singh Kushwaha
 
The breast
The breastThe breast
The breastShimranz Skillls
 
Benign breast diseases
Benign breast diseasesBenign breast diseases
Benign breast diseasesMuhammad Farooq Rao
 

Contenu connexe

Tendances

Paget disease of the breast
Paget disease of the breastPaget disease of the breast
Paget disease of the breastBashir BnYunus
 
Breast pathology 1
Breast pathology 1Breast pathology 1
Breast pathology 1Prasad CSBR
 
Prognostic factors in carcinoma breast ppt
Prognostic factors in carcinoma breast pptPrognostic factors in carcinoma breast ppt
Prognostic factors in carcinoma breast pptSwati Wadhai
 
ANDI & benign breast disorders
ANDI & benign breast disordersANDI & benign breast disorders
ANDI & benign breast disordersdileep hoysal
 
Gastric Cancer - Pathology Seminar
Gastric Cancer - Pathology SeminarGastric Cancer - Pathology Seminar
Gastric Cancer - Pathology SeminarDr. Pritika Nehra
 
PROGNOSTIC AND PREDICTIVE FACTORS FOR METASTATIC CARCINOMA BREAST
PROGNOSTIC AND PREDICTIVE FACTORS FOR METASTATIC CARCINOMA BREASTPROGNOSTIC AND PREDICTIVE FACTORS FOR METASTATIC CARCINOMA BREAST
PROGNOSTIC AND PREDICTIVE FACTORS FOR METASTATIC CARCINOMA BREASTDrAnkitaPatel
 
Renal cell carcinoma
Renal cell carcinomaRenal cell carcinoma
Renal cell carcinomaArkaprovo Roy
 
Benign and Malignant Breast Diseases
Benign and Malignant Breast DiseasesBenign and Malignant Breast Diseases
Benign and Malignant Breast Diseasesyuyuricci
 
Teratoma
TeratomaTeratoma
Teratomamo mo
 

Tendances (20)

Paget disease of the breast
Paget disease of the breastPaget disease of the breast
Paget disease of the breast
 
Pathology of Breast Disorders
Pathology of Breast DisordersPathology of Breast Disorders
Pathology of Breast Disorders
 
Breast pathology 1
Breast pathology 1Breast pathology 1
Breast pathology 1
 
CARCINOMA PENIS
CARCINOMA PENISCARCINOMA PENIS
CARCINOMA PENIS
 
OVARIAN TUMOURS
OVARIAN TUMOURSOVARIAN TUMOURS
OVARIAN TUMOURS
 
Colorectal Cancer
Colorectal CancerColorectal Cancer
Colorectal Cancer
 
Testicular tumors
Testicular tumorsTesticular tumors
Testicular tumors
 
Benign breast disease
Benign breast diseaseBenign breast disease
Benign breast disease
 
Prognostic factors in carcinoma breast ppt
Prognostic factors in carcinoma breast pptPrognostic factors in carcinoma breast ppt
Prognostic factors in carcinoma breast ppt
 
ANDI & benign breast disorders
ANDI & benign breast disordersANDI & benign breast disorders
ANDI & benign breast disorders
 
Testicular tumours
Testicular tumoursTesticular tumours
Testicular tumours
 
Gastric Cancer - Pathology Seminar
Gastric Cancer - Pathology SeminarGastric Cancer - Pathology Seminar
Gastric Cancer - Pathology Seminar
 
PROGNOSTIC AND PREDICTIVE FACTORS FOR METASTATIC CARCINOMA BREAST
PROGNOSTIC AND PREDICTIVE FACTORS FOR METASTATIC CARCINOMA BREASTPROGNOSTIC AND PREDICTIVE FACTORS FOR METASTATIC CARCINOMA BREAST
PROGNOSTIC AND PREDICTIVE FACTORS FOR METASTATIC CARCINOMA BREAST
 
Renal cell carcinoma
Renal cell carcinomaRenal cell carcinoma
Renal cell carcinoma
 
Tumor markers
Tumor markersTumor markers
Tumor markers
 
Benign and Malignant Breast Diseases
Benign and Malignant Breast DiseasesBenign and Malignant Breast Diseases
Benign and Malignant Breast Diseases
 
Thyroid neoplasms
Thyroid neoplasmsThyroid neoplasms
Thyroid neoplasms
 
Teratoma
TeratomaTeratoma
Teratoma
 
Soft tissue sarcoma
Soft tissue sarcomaSoft tissue sarcoma
Soft tissue sarcoma
 
Carcinoma rectum (Rectal Cancer)
Carcinoma rectum (Rectal Cancer)Carcinoma rectum (Rectal Cancer)
Carcinoma rectum (Rectal Cancer)
 

En vedette

Ozel durumlarda radyoloji
Ozel durumlarda radyolojiOzel durumlarda radyoloji
Ozel durumlarda radyolojiankaramhd
 
Carcinoma intraductal.
Carcinoma intraductal.Carcinoma intraductal.
Carcinoma intraductal.afffn
 
Interventions For Clients With Breast Cancer
Interventions For Clients With Breast CancerInterventions For Clients With Breast Cancer
Interventions For Clients With Breast CancerJolene Bethune
 

En vedette (7)

The breast
The breastThe breast
The breast
 
Benign breast diseases
Benign breast diseasesBenign breast diseases
Benign breast diseases
 
Breast Abscess
Breast AbscessBreast Abscess
Breast Abscess
 
Ozel durumlarda radyoloji
Ozel durumlarda radyolojiOzel durumlarda radyoloji
Ozel durumlarda radyoloji
 
Carcinoma intraductal.
Carcinoma intraductal.Carcinoma intraductal.
Carcinoma intraductal.
 
Interventions For Clients With Breast Cancer
Interventions For Clients With Breast CancerInterventions For Clients With Breast Cancer
Interventions For Clients With Breast Cancer
 
Breast Pathology Lecture - 2013
Breast Pathology Lecture - 2013Breast Pathology Lecture - 2013
Breast Pathology Lecture - 2013
 

Similaire à Breast carcinoma pathology

Ca breast molecular biology
Ca breast molecular biology Ca breast molecular biology
Ca breast molecular biology suhas k r
 
Recent advances in colorectal carcinoma
Recent advances in colorectal carcinomaRecent advances in colorectal carcinoma
Recent advances in colorectal carcinomaVikash Prasad
 
Histopathological dignosis of carcinoma of breast
Histopathological dignosis of carcinoma of breastHistopathological dignosis of carcinoma of breast
Histopathological dignosis of carcinoma of breastNazia Ashraf
 
premalignant lesions new.pptx
premalignant lesions new.pptxpremalignant lesions new.pptx
premalignant lesions new.pptxsaswati14
 
Carcinoma breast and its management (1).pptx
Carcinoma breast and its management (1).pptxCarcinoma breast and its management (1).pptx
Carcinoma breast and its management (1).pptxDr Sajad Nazir
 
Pancreatic tumours
Pancreatic tumours Pancreatic tumours
Pancreatic tumours Khyati Mehta
 
Malignant epithelial tumors iii/prosthodontic courses
Malignant epithelial tumors iii/prosthodontic coursesMalignant epithelial tumors iii/prosthodontic courses
Malignant epithelial tumors iii/prosthodontic coursesIndian dental academy
 
Pathology+of+breast+carcinoma+fsm.ac.fj
Pathology+of+breast+carcinoma+fsm.ac.fjPathology+of+breast+carcinoma+fsm.ac.fj
Pathology+of+breast+carcinoma+fsm.ac.fjshabeel pn
 
Pathology+of+breast+carcinoma+fsm.ac.fj
Pathology+of+breast+carcinoma+fsm.ac.fjPathology+of+breast+carcinoma+fsm.ac.fj
Pathology+of+breast+carcinoma+fsm.ac.fjshabeel pn
 
Breast cancer. TNM as a logical model in Cancer Diagnosis
Breast cancer. TNM as a logical model in Cancer DiagnosisBreast cancer. TNM as a logical model in Cancer Diagnosis
Breast cancer. TNM as a logical model in Cancer DiagnosisEneutron
 
aetiology,pathology & clinical features of breast cancer
aetiology,pathology & clinical features of breast cancer aetiology,pathology & clinical features of breast cancer
aetiology,pathology & clinical features of breast cancerSumer Yadav
 
5. breast carcinoma histopathology types and clinical features
5. breast carcinoma histopathology types and clinical features5. breast carcinoma histopathology types and clinical features
5. breast carcinoma histopathology types and clinical featuresDr SANTHIPRIYA GOPASANA
 
Slides of benign epithelium t.
Slides of benign epithelium t.Slides of benign epithelium t.
Slides of benign epithelium t.Alaa Radwan
 
Breast benign disorders pathology
Breast benign disorders pathologyBreast benign disorders pathology
Breast benign disorders pathologyKripa Vijay
 

Similaire à Breast carcinoma pathology (20)

Ca breast molecular biology
Ca breast molecular biology Ca breast molecular biology
Ca breast molecular biology
 
Manik crc final
Manik crc finalManik crc final
Manik crc final
 
Cervical cancer
Cervical cancerCervical cancer
Cervical cancer
 
Recent advances in colorectal carcinoma
Recent advances in colorectal carcinomaRecent advances in colorectal carcinoma
Recent advances in colorectal carcinoma
 
Histopathological dignosis of carcinoma of breast
Histopathological dignosis of carcinoma of breastHistopathological dignosis of carcinoma of breast
Histopathological dignosis of carcinoma of breast
 
premalignant lesions new.pptx
premalignant lesions new.pptxpremalignant lesions new.pptx
premalignant lesions new.pptx
 
Carcinoma breast and its management (1).pptx
Carcinoma breast and its management (1).pptxCarcinoma breast and its management (1).pptx
Carcinoma breast and its management (1).pptx
 
Pancreatic tumours
Pancreatic tumours Pancreatic tumours
Pancreatic tumours
 
Ovarian tumors
Ovarian tumorsOvarian tumors
Ovarian tumors
 
Malignant epithelial tumors iii/prosthodontic courses
Malignant epithelial tumors iii/prosthodontic coursesMalignant epithelial tumors iii/prosthodontic courses
Malignant epithelial tumors iii/prosthodontic courses
 
Pathology+of+breast+carcinoma+fsm.ac.fj
Pathology+of+breast+carcinoma+fsm.ac.fjPathology+of+breast+carcinoma+fsm.ac.fj
Pathology+of+breast+carcinoma+fsm.ac.fj
 
Pathology+of+breast+carcinoma+fsm.ac.fj
Pathology+of+breast+carcinoma+fsm.ac.fjPathology+of+breast+carcinoma+fsm.ac.fj
Pathology+of+breast+carcinoma+fsm.ac.fj
 
Pancreas 2
Pancreas 2Pancreas 2
Pancreas 2
 
Breast cancer. TNM as a logical model in Cancer Diagnosis
Breast cancer. TNM as a logical model in Cancer DiagnosisBreast cancer. TNM as a logical model in Cancer Diagnosis
Breast cancer. TNM as a logical model in Cancer Diagnosis
 
aetiology,pathology & clinical features of breast cancer
aetiology,pathology & clinical features of breast cancer aetiology,pathology & clinical features of breast cancer
aetiology,pathology & clinical features of breast cancer
 
TUMORES RAROS DE LA MAMA.pdf
TUMORES RAROS DE LA MAMA.pdfTUMORES RAROS DE LA MAMA.pdf
TUMORES RAROS DE LA MAMA.pdf
 
Salivary gland tumors
Salivary gland tumorsSalivary gland tumors
Salivary gland tumors
 
5. breast carcinoma histopathology types and clinical features
5. breast carcinoma histopathology types and clinical features5. breast carcinoma histopathology types and clinical features
5. breast carcinoma histopathology types and clinical features
 
Slides of benign epithelium t.
Slides of benign epithelium t.Slides of benign epithelium t.
Slides of benign epithelium t.
 
Breast benign disorders pathology
Breast benign disorders pathologyBreast benign disorders pathology
Breast benign disorders pathology
 

Dernier

Lippincott Microcards_ Microbiology Flash Cards-LWW (2015).pdf
Lippincott Microcards_ Microbiology Flash Cards-LWW (2015).pdfLippincott Microcards_ Microbiology Flash Cards-LWW (2015).pdf
Lippincott Microcards_ Microbiology Flash Cards-LWW (2015).pdfSreeja Cherukuru
 
Big Data Analysis Suggests COVID Vaccination Increases Excess Mortality Of ...
Big Data Analysis Suggests COVID Vaccination Increases Excess Mortality Of ...Big Data Analysis Suggests COVID Vaccination Increases Excess Mortality Of ...
Big Data Analysis Suggests COVID Vaccination Increases Excess Mortality Of ...sdateam0
 
See the 2,456 pharmacies on the National E-Pharmacy Platform
See the 2,456 pharmacies on the National E-Pharmacy PlatformSee the 2,456 pharmacies on the National E-Pharmacy Platform
See the 2,456 pharmacies on the National E-Pharmacy PlatformKweku Zurek
 
COVID-19 (NOVEL CORONA VIRUS DISEASE PANDEMIC ).pptx
COVID-19 (NOVEL CORONA VIRUS DISEASE PANDEMIC ).pptxCOVID-19 (NOVEL CORONA VIRUS DISEASE PANDEMIC ).pptx
COVID-19 (NOVEL CORONA VIRUS DISEASE PANDEMIC ).pptxBibekananda shah
 
Informed Consent Empowering Healthcare Decision-Making.pptx
Informed Consent Empowering Healthcare Decision-Making.pptxInformed Consent Empowering Healthcare Decision-Making.pptx
Informed Consent Empowering Healthcare Decision-Making.pptxSasikiranMarri
 
Introduction to Sports Injuries by- Dr. Anjali Rai
Introduction to Sports Injuries by- Dr. Anjali RaiIntroduction to Sports Injuries by- Dr. Anjali Rai
Introduction to Sports Injuries by- Dr. Anjali RaiGoogle
 
Report Back from SGO: What’s New in Uterine Cancer?.pptx
Report Back from SGO: What’s New in Uterine Cancer?.pptxReport Back from SGO: What’s New in Uterine Cancer?.pptx
Report Back from SGO: What’s New in Uterine Cancer?.pptxbkling
 
Wessex Health Partners Wessex Integrated Care, Population Health, Research & ...
Wessex Health Partners Wessex Integrated Care, Population Health, Research & ...Wessex Health Partners Wessex Integrated Care, Population Health, Research & ...
Wessex Health Partners Wessex Integrated Care, Population Health, Research & ...Wessex Health Partners
 
Pharmaceutical Marketting: Unit-5, Pricing
Pharmaceutical Marketting: Unit-5, PricingPharmaceutical Marketting: Unit-5, Pricing
Pharmaceutical Marketting: Unit-5, PricingArunagarwal328757
 
POST NATAL EXERCISES AND ITS IMPACT.pptx
POST NATAL EXERCISES AND ITS IMPACT.pptxPOST NATAL EXERCISES AND ITS IMPACT.pptx
POST NATAL EXERCISES AND ITS IMPACT.pptxvirengeeta
 
call girls in munirka DELHI 🔝 >༒9540349809 🔝 genuine Escort Service 🔝✔️✔️
call girls in munirka DELHI 🔝 >༒9540349809 🔝 genuine Escort Service 🔝✔️✔️call girls in munirka DELHI 🔝 >༒9540349809 🔝 genuine Escort Service 🔝✔️✔️
call girls in munirka DELHI 🔝 >༒9540349809 🔝 genuine Escort Service 🔝✔️✔️saminamagar
 
call girls in Connaught Place DELHI 🔝 >༒9540349809 🔝 genuine Escort Service ...
call girls in Connaught Place DELHI 🔝 >༒9540349809 🔝 genuine Escort Service ...call girls in Connaught Place DELHI 🔝 >༒9540349809 🔝 genuine Escort Service ...
call girls in Connaught Place DELHI 🔝 >༒9540349809 🔝 genuine Escort Service ...saminamagar
 
LUNG TUMORS AND ITS CLASSIFICATIONS.pdf
LUNG TUMORS AND ITS CLASSIFICATIONS.pdfLUNG TUMORS AND ITS CLASSIFICATIONS.pdf
LUNG TUMORS AND ITS CLASSIFICATIONS.pdfDolisha Warbi
 
Glomerular Filtration rate and its determinants.pptx
Glomerular Filtration rate and its determinants.pptxGlomerular Filtration rate and its determinants.pptx
Glomerular Filtration rate and its determinants.pptxDr.Nusrat Tariq
 
PULMONARY EMBOLISM AND ITS MANAGEMENTS.pdf
PULMONARY EMBOLISM AND ITS MANAGEMENTS.pdfPULMONARY EMBOLISM AND ITS MANAGEMENTS.pdf
PULMONARY EMBOLISM AND ITS MANAGEMENTS.pdfDolisha Warbi
 
VarSeq 2.6.0: Advancing Pharmacogenomics and Genomic Analysis
VarSeq 2.6.0: Advancing Pharmacogenomics and Genomic AnalysisVarSeq 2.6.0: Advancing Pharmacogenomics and Genomic Analysis
VarSeq 2.6.0: Advancing Pharmacogenomics and Genomic AnalysisGolden Helix
 
Measurement of Radiation and Dosimetric Procedure.pptx
Measurement of Radiation and Dosimetric Procedure.pptxMeasurement of Radiation and Dosimetric Procedure.pptx
Measurement of Radiation and Dosimetric Procedure.pptxDr. Dheeraj Kumar
 
Music Therapy's Impact in Palliative Care| IAPCON2024| Dr. Tara Rajendran
Music Therapy's Impact in Palliative Care| IAPCON2024| Dr. Tara RajendranMusic Therapy's Impact in Palliative Care| IAPCON2024| Dr. Tara Rajendran
Music Therapy's Impact in Palliative Care| IAPCON2024| Dr. Tara RajendranTara Rajendran
 
world health day presentation ppt download
world health day presentation ppt downloadworld health day presentation ppt download
world health day presentation ppt downloadAnkitKumar311566
 
SWD (Short wave diathermy)- Physiotherapy.ppt
SWD (Short wave diathermy)- Physiotherapy.pptSWD (Short wave diathermy)- Physiotherapy.ppt
SWD (Short wave diathermy)- Physiotherapy.pptMumux Mirani
 

Dernier (20)

Lippincott Microcards_ Microbiology Flash Cards-LWW (2015).pdf
Lippincott Microcards_ Microbiology Flash Cards-LWW (2015).pdfLippincott Microcards_ Microbiology Flash Cards-LWW (2015).pdf
Lippincott Microcards_ Microbiology Flash Cards-LWW (2015).pdf
 
Big Data Analysis Suggests COVID Vaccination Increases Excess Mortality Of ...
Big Data Analysis Suggests COVID Vaccination Increases Excess Mortality Of ...Big Data Analysis Suggests COVID Vaccination Increases Excess Mortality Of ...
Big Data Analysis Suggests COVID Vaccination Increases Excess Mortality Of ...
 
See the 2,456 pharmacies on the National E-Pharmacy Platform
See the 2,456 pharmacies on the National E-Pharmacy PlatformSee the 2,456 pharmacies on the National E-Pharmacy Platform
See the 2,456 pharmacies on the National E-Pharmacy Platform
 
COVID-19 (NOVEL CORONA VIRUS DISEASE PANDEMIC ).pptx
COVID-19 (NOVEL CORONA VIRUS DISEASE PANDEMIC ).pptxCOVID-19 (NOVEL CORONA VIRUS DISEASE PANDEMIC ).pptx
COVID-19 (NOVEL CORONA VIRUS DISEASE PANDEMIC ).pptx
 
Informed Consent Empowering Healthcare Decision-Making.pptx
Informed Consent Empowering Healthcare Decision-Making.pptxInformed Consent Empowering Healthcare Decision-Making.pptx
Informed Consent Empowering Healthcare Decision-Making.pptx
 
Introduction to Sports Injuries by- Dr. Anjali Rai
Introduction to Sports Injuries by- Dr. Anjali RaiIntroduction to Sports Injuries by- Dr. Anjali Rai
Introduction to Sports Injuries by- Dr. Anjali Rai
 
Report Back from SGO: What’s New in Uterine Cancer?.pptx
Report Back from SGO: What’s New in Uterine Cancer?.pptxReport Back from SGO: What’s New in Uterine Cancer?.pptx
Report Back from SGO: What’s New in Uterine Cancer?.pptx
 
Wessex Health Partners Wessex Integrated Care, Population Health, Research & ...
Wessex Health Partners Wessex Integrated Care, Population Health, Research & ...Wessex Health Partners Wessex Integrated Care, Population Health, Research & ...
Wessex Health Partners Wessex Integrated Care, Population Health, Research & ...
 
Pharmaceutical Marketting: Unit-5, Pricing
Pharmaceutical Marketting: Unit-5, PricingPharmaceutical Marketting: Unit-5, Pricing
Pharmaceutical Marketting: Unit-5, Pricing
 
POST NATAL EXERCISES AND ITS IMPACT.pptx
POST NATAL EXERCISES AND ITS IMPACT.pptxPOST NATAL EXERCISES AND ITS IMPACT.pptx
POST NATAL EXERCISES AND ITS IMPACT.pptx
 
call girls in munirka DELHI 🔝 >༒9540349809 🔝 genuine Escort Service 🔝✔️✔️
call girls in munirka DELHI 🔝 >༒9540349809 🔝 genuine Escort Service 🔝✔️✔️call girls in munirka DELHI 🔝 >༒9540349809 🔝 genuine Escort Service 🔝✔️✔️
call girls in munirka DELHI 🔝 >༒9540349809 🔝 genuine Escort Service 🔝✔️✔️
 
call girls in Connaught Place DELHI 🔝 >༒9540349809 🔝 genuine Escort Service ...
call girls in Connaught Place DELHI 🔝 >༒9540349809 🔝 genuine Escort Service ...call girls in Connaught Place DELHI 🔝 >༒9540349809 🔝 genuine Escort Service ...
call girls in Connaught Place DELHI 🔝 >༒9540349809 🔝 genuine Escort Service ...
 
LUNG TUMORS AND ITS CLASSIFICATIONS.pdf
LUNG TUMORS AND ITS CLASSIFICATIONS.pdfLUNG TUMORS AND ITS CLASSIFICATIONS.pdf
LUNG TUMORS AND ITS CLASSIFICATIONS.pdf
 
Glomerular Filtration rate and its determinants.pptx
Glomerular Filtration rate and its determinants.pptxGlomerular Filtration rate and its determinants.pptx
Glomerular Filtration rate and its determinants.pptx
 
PULMONARY EMBOLISM AND ITS MANAGEMENTS.pdf
PULMONARY EMBOLISM AND ITS MANAGEMENTS.pdfPULMONARY EMBOLISM AND ITS MANAGEMENTS.pdf
PULMONARY EMBOLISM AND ITS MANAGEMENTS.pdf
 
VarSeq 2.6.0: Advancing Pharmacogenomics and Genomic Analysis
VarSeq 2.6.0: Advancing Pharmacogenomics and Genomic AnalysisVarSeq 2.6.0: Advancing Pharmacogenomics and Genomic Analysis
VarSeq 2.6.0: Advancing Pharmacogenomics and Genomic Analysis
 
Measurement of Radiation and Dosimetric Procedure.pptx
Measurement of Radiation and Dosimetric Procedure.pptxMeasurement of Radiation and Dosimetric Procedure.pptx
Measurement of Radiation and Dosimetric Procedure.pptx
 
Music Therapy's Impact in Palliative Care| IAPCON2024| Dr. Tara Rajendran
Music Therapy's Impact in Palliative Care| IAPCON2024| Dr. Tara RajendranMusic Therapy's Impact in Palliative Care| IAPCON2024| Dr. Tara Rajendran
Music Therapy's Impact in Palliative Care| IAPCON2024| Dr. Tara Rajendran
 
world health day presentation ppt download
world health day presentation ppt downloadworld health day presentation ppt download
world health day presentation ppt download
 
SWD (Short wave diathermy)- Physiotherapy.ppt
SWD (Short wave diathermy)- Physiotherapy.pptSWD (Short wave diathermy)- Physiotherapy.ppt
SWD (Short wave diathermy)- Physiotherapy.ppt
 

Breast carcinoma pathology

  • 1. Dr. P. Karpagam Kiruba Rajeswari, M.B.B.S.,D.C.P., Tutor in Pathology, MAPIMS
  • 2.
  • 3. BREAST CARCINOMA – RISK FACTORS
  • 4.  
  • 5.  
  • 6.  
  • 7.
  • 8.
  • 9.
  • 10.
  • 11.
  • 12.
  • 13.  
  • 14.
  • 15.
  • 16.
  • 17.  
  • 18.
  • 19.
  • 20.
  • 21.
  • 23.
  • 24.
  • 25.
  • 26.
  • 27.
  • 28.  
  • 29.
  • 30.
  • 31. Invasive Carcinoma – NST- HPE Features Well diff. Ca Mod. diff.Ca Poorly diff. Ca. Tubule formation Prominent Less,solid clusters/single infiltrating cells Ragged nests/solid sheets of cells Nuclei Small,round,monomorphic Greater nuclear pleomorphism Nuclei – enlarged,irregular. Mitotic figures Rare Present Numerous Proliferation rate - - High Tumour necrosis - - Present
  • 32.
  • 33.
  • 34.
  • 35.
  • 36.
  • 37.
  • 38.
  • 39.
  • 40.
  • 41.
  • 42.
  • 43.
  • 44.
  • 45. Stage T: Primary Cancer Lymph Nodes (LNs) M: Distant Metastasis 5-Year Survival (%) 0 DCIS or LCIS No metastases Absent 92 I Invasive carcinoma ≤2 cm No metastases Absent 87 II Invasive carcinoma >2 cm No metastases Absent 75 Invasive carcinoma <5 cm 1 to 3 positive LNs Absent III Invasive carcinoma >5 cm 1 to 3 positive LNs Absent 46 Any size invasive carcinoma ≥ 4 positive LNs Absent Invasive carcinoma with skin or chest wall involvement or inflammatory carcinoma 0 to >10 positive LNs. Absent IV Any size invasive carcinoma Negative or positive lymph nodes Present 13
  • 47.  
  • 48.  
  • 49.  
  • 50.  
  • 51.
  • 52.
  • 53.
  • 54.
  • 55.
  • 56.  
  • 57.
  • 58.
  • 59.