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ITK in an  Industrial Research Lab GE Research Jim Miller Bill Lorensen Dan Blezek Majeid Alyassin John Schenck Zhu Li Matt Turek Paulo Mendon ç a Dirk Padfield James Ross
ITK at GE Research ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],                                                             
Alzheimer’s Research ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Brain Iron as AD Marker Alzheimer’s Disease Normal HIV
Brain Iron Regional Quantification ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Global Regional
Longitudinal MRI with no registration Checkerboard Source Original image Difference Target Original image
Longitudinal MRI with mutual information registration Checkerboard Source Original image Difference Target Original image
Design of Experiments
Brain Iron Anatomical Quantification ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Global Regional Structural
 
Automatic Brain Structure Segmentation ,[object Object],[object Object],[object Object]
Chronic Obstructive Pulmonary Disease ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],COPD is the 4 th  leading cause of death in the US.
Emphysema ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],5 class and 3 class performance
Chronic Bronchitis Inlier  model TPS Higher order shape models Inlier  model TPS Strong model, robust fits
Airway wall study ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
120-2 Lumen Error: 4.2% Wall Error: 38.3% 120-3 Lumen Error: 38.3% Wall Error: 54.1% 177-3 Lumen Error: 57.7% Wall Error: 410.9% 12-2 Lumen Error: 24.6% Wall Error: 25.7% 103-1 Lumen Error: 2.9% Wall Error: 6.2%
Pig Airway 102-1  (9 mm Lumen Diameter) Pathology Measurements Automatic CT Measurements Lumen Area:  75.02 mm 2 Wall Area:  101.15 mm 2 Lumen Area:  75.27 mm 2  (0.32 % Error) Wall Area:  107.38 mm 2  (6.2 % Error)
Pig Airway 177-3  (~1 mm Lumen Diameter) Pathology Measurements Automatic CT Measurements Lumen Area:  1.36 mm 2 Wall Area:  2.54 mm 2 Lumen Area:  2.14 mm 2  (57.7 % Error) Wall Area:  12.96 mm 2  (410.9 % Error)
Other ITK Applications ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Histogram Tumor Background
Life at an Industrial Research Lab Academia Publish Publish Publish How Why Industry Product Product Product What When Industrial Research Evaluate Accelerate Harden Extend Invent

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ITK Tutorial Presentation Slides-952

  • 1. ITK in an Industrial Research Lab GE Research Jim Miller Bill Lorensen Dan Blezek Majeid Alyassin John Schenck Zhu Li Matt Turek Paulo Mendon ç a Dirk Padfield James Ross
  • 2.
  • 3.
  • 4. Brain Iron as AD Marker Alzheimer’s Disease Normal HIV
  • 5.
  • 6. Longitudinal MRI with no registration Checkerboard Source Original image Difference Target Original image
  • 7. Longitudinal MRI with mutual information registration Checkerboard Source Original image Difference Target Original image
  • 9.
  • 10.  
  • 11.
  • 12.
  • 13.
  • 14. Chronic Bronchitis Inlier model TPS Higher order shape models Inlier model TPS Strong model, robust fits
  • 15.
  • 16. 120-2 Lumen Error: 4.2% Wall Error: 38.3% 120-3 Lumen Error: 38.3% Wall Error: 54.1% 177-3 Lumen Error: 57.7% Wall Error: 410.9% 12-2 Lumen Error: 24.6% Wall Error: 25.7% 103-1 Lumen Error: 2.9% Wall Error: 6.2%
  • 17. Pig Airway 102-1 (9 mm Lumen Diameter) Pathology Measurements Automatic CT Measurements Lumen Area: 75.02 mm 2 Wall Area: 101.15 mm 2 Lumen Area: 75.27 mm 2 (0.32 % Error) Wall Area: 107.38 mm 2 (6.2 % Error)
  • 18. Pig Airway 177-3 (~1 mm Lumen Diameter) Pathology Measurements Automatic CT Measurements Lumen Area: 1.36 mm 2 Wall Area: 2.54 mm 2 Lumen Area: 2.14 mm 2 (57.7 % Error) Wall Area: 12.96 mm 2 (410.9 % Error)
  • 19.
  • 21. Life at an Industrial Research Lab Academia Publish Publish Publish How Why Industry Product Product Product What When Industrial Research Evaluate Accelerate Harden Extend Invent