2. Objectives Describe some common genetic diseases Examine selective breeding Discuss cloning Analyze genetic engineering Describe current genetic research Construct personal pedigree
3. Ways to Cause Genetic Disease Mutation in DNA of genes Alteration in structure of a chromosome Change in the number of chromosomes
4. Cystic Fibrosis Recessive disease Affect 1:31 births Disease: Produce abnormally thick mucus Die early due to infection 118
5. Sickle-Cell Anemia Recessive Disease Discovered in 1910 Single nucleotide change from T to A 70,000 American’s Chronic body problems 118
12. Selective Breeding Process of selecting organisms with desired traits to be the parents of the next generation What desired traits would you like in a dog? 124
13. Inbreeding Breed individuals with similar traits Turkey Plump Quickly maturing Will also inherit similar genetic defects 124
18. Modern Genetics Human Genome Project 30,000 genes Average gene is 3,000 bases long DNA Fingerprinting Cut up DNA and look for difference that can identify individuals