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Canadian Transplantation Highlights
1956: Heart valve* transplants are performed in Toronto, Ontario.
1958: First successful kidney transplant, between identical twins, is performed at the Royal Victoria Hospital in
Montreal, Quebec.
1963:First kidney transplant from a deceased donor is performed in Montreal, Quebec.
1968:First heart transplant is performed in Montreal, Quebec.
1970:First liver transplant is performed in Montreal, Quebec.
1974:First pediatric bone marrow transplant is performed in Toronto, Ontario.
1983:First heart-lung transplant is performed at the University Hospital in London, Ontario.
Successful single lung* transplant is performed at the Toronto General Hospital in Ontario.
1986:Successful double lung* transplant is performed at the Toronto General Hospital in Ontario.
1988:Successful liver-bowel* transplant is performed at the University Hospital in London, Ontario.
1989:Islet cells are transplanted into a patient with diabetes at the University of Alberta Hospital in Edmonton.
1993:First living-related (parent to child) partial liver transplant is performed in London, Ontario.
1995:In Montreal, Quebec, pig liver tissue is used as a bridge to keep a patient alive until a human liver became
available for transplant.
1997:The London Health Sciences Centre in Ontario transplants a liver, bowel, stomach, and pancreas into a five-
month-old infant – the world's youngest recipient of a multi-organ transplant.
2000:First adult-to-adult living liver transplant is performed in London, Ontario.
2004:First live kidney donor transplant from an anonymous donor to an unrelated recipient is performed in Vancouver,
British Columbia.
*A world first
2015 Joint Meeting A Triumph of Canadian
Innovation and Cooperation, Like 1983!
The Banff Process
Consensus communication in renal transplantation
a
The Banff lesions
g, i, t, v - score
The Banff
community
Pathologists
Nephrologists
Tx-Surgeons
Lab-Medicine
established by
consensus in 1991
The Banff
classification
Current consensus for
diagnostics
moderated
Banff meetings
thesis-antithesis-synthesis
tentative
thresholds
participate
refinementBanff Working
Groups
Feedback concerning weaknesses and strengths by results from
independent research
New members
Biostaticians
Molecular Biologists
“Omics”-specialists
Off-springs
Liver
Pancreas
Lung, Heart
CTA
• 1991 First Conference
• 1993 First Kidney International publication
• 1995 Integration with CADI
• 1997 Integration with CCTT classification
• 1999 Second KI paper. Clinical practice guidelines. Implantation biopsies.
• 2001 Classification of antibody-mediated rejection (ABMR): Regulatory agencies participating
• 2003 Genomics focus, ptc cell accumulation scoring
• 2005 Gene chip analysis. Elimination of CAN, identification of chronic antibody-mediated
rejection.
• 2007 First meeting far from a town called “Banff” – La Coruna, Spain.
• 2009 Working groups. Meeting in Banff, Alberta, Canada
• 2013 Establishment of Banff Foundation for Allograft Pathology and recognition of C4d-
negative ABMR
Significance of ‘Banff papers’
• 4244 citations of the 9 Banff meeting reports
• 790 Banff / Transplantation papers in PubMed
• Banff 2003 meeting report (ABMR criteria) = most cited AJT paper
• 3 Banff meeting reports are among the top 4 cited AJT articles
Steven Paraskevas, MD, PhD
President CST
8
CST is…
• THE multidisciplinary professional organization of Canada’s organ donation and
transplantation community.
• An association comprising close to 700 members and associate members
• A professional NFP with longstanding ties to international partner
organizations
• A dynamic player in the OTDT landscape continually re-evaluating its
relationship with agencies its own members helped lobby to create
• Now in its 35th year
• A longstanding affiliate of the TTS
9
10
Teaching, education
and professional
development
Developing consensus,
best practices and
expert opinion
Fostering research and
knowledge creation
• CST meeting has grown to showcase research from across Canada and around the world
• Joint symposia with other societies: AST, CSN, CSI
• Webinar series with the Transplantation Society
• 2013 CST successfully negotiated the designation of SOT as an Area of Focused Competence within the Royal
College
• CST sponsors multiple annual training awards
• The CST ASM is the principal venue for networking among the SOT and HLA specialties
• CST is represented in all major committees at CBS
• Special interest groups of our membership have always held annual or semi-annual networking/priority setting
meetings during the ASM: Kidney, Liver, Pancreas/Islet, Lung, Heart, Pediatric, Pharmacy, Allied Health, HLA,
Donation
• Canadian National Transplant Research Program (CNTRP) holds group meeting at the ASM, as well as showcasing
its annual achievements
CANADIAN SOCIETY OF TRANSPLANTATION
SOCIÉTÉ CANADIENNE DE TRANSPLANTATION
2014-2015
CST President
Steven Paraskevas
CST Board
Past-President,Tom Blydt-Hansen
Vice-President,Atul Humar
Secretary,IanAlwayn
Treasurer,David Grant
Council
Gallaher Membership Services Inc.
Executive Director,Rob Gallaher
Project Manager,Holly Fan
Groups Committees (Chair,Co-Chair)
CanadianTransplant Academy
3 Immediate Past Presidents
Allied Health
Cardiac (CCTN)
Donation
HLA
Kidney
Liver Network
Lung
Pancreas
Pediatric
Pharmacist
Allied Health,Janet Madill
Cardiac,Debra Isaac
Donation,Adrian Robertson
HLA,Trish Campbell
Kidney,Jeff Zaltzman
Liver,IanAlwayn
Lung,Lianne Singer
Pancreas,Jeffrey Schiff
Pediatric,Susan Samuel
Pharmacist,Chris Daley
Members-At-Large
Tammy Keough-Ryan
Joseph Kim
Michael Mengel
JeanTchervenkov
KathrynTinckam
Liaison Officers
JennyWichart,
Associate Member
Sam Shemie,Critical
Care Donation
Specialist
Communications,J.Gill,J.Schiff
Ethics,MC.Fortin,R.Greeberg
Education,J.Schiff
Leading Clinical Practice,E.Renner,Y.Avitzur
Grants &Awards,R.Prasad,M.Paquet
Governance & Nominations,T.Blydt-Hansen,K.Tinckam
Public Policy,T.Fairhead,J.Zaltzman
Research,J.Kim,MJ.Hebert
Scientific Meetings,P.Chaudhury,J.Gill
Standards,C.Beninger,P.Chaudhury
Joint Banff/CST
Program Committee
Co-chairs: Dr. Alexandre
Loupy and Dr. Prosanto
Chaudhury
2015 Banff/CST Meeting Organizing Corporation
(“2015 MOC”) – Co-Directors: Dr. John Gill, Dr. Michael Mengel
Members: Anthony Jevnikar, David Rush, Denis Glotz, Kim Solez,
Marcelo Cantarovich, Mark Haas, Steven Paraskevas
Joint Banff/CST
Finance Committee
Joint Program Structure
Banff activies Joint activities CST activities
2015 CST /
Banff
meeting
program
Day 1: Monday Day 2: Tuesday Day 3: Wednesday Day 4: Thursday Day 5: Friday Day 6: Saturday
Session Potential Banff-premeeting Plenary Session: Progress Report
Banff Working groups
Joint Pleanary session I: Joint Pleanary session II: Concurrent sessions: Banff
meeting summary and CST
symposia
08:00 - 08:30
08:30 - 09:00
09:00 - 09:30
09:30 - 10:00
10:00 - 10:30 Coffee break Coffee break Coffee break Coffee break Coffee break Coffee break
10:30 - 11:00
11:00 - 11:30
11:30 - 12:00
12:00 - 01:00 Working Lunch: Banff registration
open
Working Lunch: Working Lunch: CST registration
open
Working Lunch: Lunch: Banff adjourns Lunch:
Session Potential Banff-premeeting Concurrent Organ Sessions Concurrent sessions: Banff
Organ sessions and CST
Working groups
Concurrent sessions: Banff
Organ sessions and CST
symposia
01:00 - 01:30
01:30 - 02:00
02:00 - 02:30
02:30 - 03:00
03:00 - 03:30 Coffee break Coffee break Coffee break Coffee break Coffee break Coffee break
03:30 - 04:00
04:00 - 04:30
04:30 - 05:00
05:00 - 05:30
05:30 - 06:00
Events
6:30 Welcome Reception - Cocktails and
snacks. Open bar
Case presentations from varioous
organs with Wine Beer and Food
Joint Poster Session with reception CST Awards and Joint CST/Banff
Gala Dinner
CST President's dinner
Target Audience for the 2015 joint CST/Banff meeting:
total ~600 expected international delegates
• Basic Scientists
• Pathologists
• Immunogeneticists and HLA experts
• Transplant Physicians: Internal Medicine, Surgery,
Infectious Diseases, Critical Care
• Allied Health Care
• Students, Trainees, Fellows

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Canadian Transplantation: A History of Innovation and Collaboration

  • 1.
  • 2. Canadian Transplantation Highlights 1956: Heart valve* transplants are performed in Toronto, Ontario. 1958: First successful kidney transplant, between identical twins, is performed at the Royal Victoria Hospital in Montreal, Quebec. 1963:First kidney transplant from a deceased donor is performed in Montreal, Quebec. 1968:First heart transplant is performed in Montreal, Quebec. 1970:First liver transplant is performed in Montreal, Quebec. 1974:First pediatric bone marrow transplant is performed in Toronto, Ontario. 1983:First heart-lung transplant is performed at the University Hospital in London, Ontario. Successful single lung* transplant is performed at the Toronto General Hospital in Ontario. 1986:Successful double lung* transplant is performed at the Toronto General Hospital in Ontario. 1988:Successful liver-bowel* transplant is performed at the University Hospital in London, Ontario. 1989:Islet cells are transplanted into a patient with diabetes at the University of Alberta Hospital in Edmonton. 1993:First living-related (parent to child) partial liver transplant is performed in London, Ontario. 1995:In Montreal, Quebec, pig liver tissue is used as a bridge to keep a patient alive until a human liver became available for transplant. 1997:The London Health Sciences Centre in Ontario transplants a liver, bowel, stomach, and pancreas into a five- month-old infant – the world's youngest recipient of a multi-organ transplant. 2000:First adult-to-adult living liver transplant is performed in London, Ontario. 2004:First live kidney donor transplant from an anonymous donor to an unrelated recipient is performed in Vancouver, British Columbia. *A world first
  • 3. 2015 Joint Meeting A Triumph of Canadian Innovation and Cooperation, Like 1983!
  • 4. The Banff Process Consensus communication in renal transplantation a The Banff lesions g, i, t, v - score The Banff community Pathologists Nephrologists Tx-Surgeons Lab-Medicine established by consensus in 1991 The Banff classification Current consensus for diagnostics moderated Banff meetings thesis-antithesis-synthesis tentative thresholds participate refinementBanff Working Groups Feedback concerning weaknesses and strengths by results from independent research New members Biostaticians Molecular Biologists “Omics”-specialists Off-springs Liver Pancreas Lung, Heart CTA
  • 5. • 1991 First Conference • 1993 First Kidney International publication • 1995 Integration with CADI • 1997 Integration with CCTT classification • 1999 Second KI paper. Clinical practice guidelines. Implantation biopsies. • 2001 Classification of antibody-mediated rejection (ABMR): Regulatory agencies participating • 2003 Genomics focus, ptc cell accumulation scoring • 2005 Gene chip analysis. Elimination of CAN, identification of chronic antibody-mediated rejection. • 2007 First meeting far from a town called “Banff” – La Coruna, Spain. • 2009 Working groups. Meeting in Banff, Alberta, Canada • 2013 Establishment of Banff Foundation for Allograft Pathology and recognition of C4d- negative ABMR
  • 6. Significance of ‘Banff papers’ • 4244 citations of the 9 Banff meeting reports • 790 Banff / Transplantation papers in PubMed • Banff 2003 meeting report (ABMR criteria) = most cited AJT paper • 3 Banff meeting reports are among the top 4 cited AJT articles
  • 7.
  • 8. Steven Paraskevas, MD, PhD President CST 8
  • 9. CST is… • THE multidisciplinary professional organization of Canada’s organ donation and transplantation community. • An association comprising close to 700 members and associate members • A professional NFP with longstanding ties to international partner organizations • A dynamic player in the OTDT landscape continually re-evaluating its relationship with agencies its own members helped lobby to create • Now in its 35th year • A longstanding affiliate of the TTS 9
  • 10. 10 Teaching, education and professional development Developing consensus, best practices and expert opinion Fostering research and knowledge creation • CST meeting has grown to showcase research from across Canada and around the world • Joint symposia with other societies: AST, CSN, CSI • Webinar series with the Transplantation Society • 2013 CST successfully negotiated the designation of SOT as an Area of Focused Competence within the Royal College • CST sponsors multiple annual training awards • The CST ASM is the principal venue for networking among the SOT and HLA specialties • CST is represented in all major committees at CBS • Special interest groups of our membership have always held annual or semi-annual networking/priority setting meetings during the ASM: Kidney, Liver, Pancreas/Islet, Lung, Heart, Pediatric, Pharmacy, Allied Health, HLA, Donation • Canadian National Transplant Research Program (CNTRP) holds group meeting at the ASM, as well as showcasing its annual achievements
  • 11. CANADIAN SOCIETY OF TRANSPLANTATION SOCIÉTÉ CANADIENNE DE TRANSPLANTATION 2014-2015 CST President Steven Paraskevas CST Board Past-President,Tom Blydt-Hansen Vice-President,Atul Humar Secretary,IanAlwayn Treasurer,David Grant Council Gallaher Membership Services Inc. Executive Director,Rob Gallaher Project Manager,Holly Fan Groups Committees (Chair,Co-Chair) CanadianTransplant Academy 3 Immediate Past Presidents Allied Health Cardiac (CCTN) Donation HLA Kidney Liver Network Lung Pancreas Pediatric Pharmacist Allied Health,Janet Madill Cardiac,Debra Isaac Donation,Adrian Robertson HLA,Trish Campbell Kidney,Jeff Zaltzman Liver,IanAlwayn Lung,Lianne Singer Pancreas,Jeffrey Schiff Pediatric,Susan Samuel Pharmacist,Chris Daley Members-At-Large Tammy Keough-Ryan Joseph Kim Michael Mengel JeanTchervenkov KathrynTinckam Liaison Officers JennyWichart, Associate Member Sam Shemie,Critical Care Donation Specialist Communications,J.Gill,J.Schiff Ethics,MC.Fortin,R.Greeberg Education,J.Schiff Leading Clinical Practice,E.Renner,Y.Avitzur Grants &Awards,R.Prasad,M.Paquet Governance & Nominations,T.Blydt-Hansen,K.Tinckam Public Policy,T.Fairhead,J.Zaltzman Research,J.Kim,MJ.Hebert Scientific Meetings,P.Chaudhury,J.Gill Standards,C.Beninger,P.Chaudhury
  • 12. Joint Banff/CST Program Committee Co-chairs: Dr. Alexandre Loupy and Dr. Prosanto Chaudhury 2015 Banff/CST Meeting Organizing Corporation (“2015 MOC”) – Co-Directors: Dr. John Gill, Dr. Michael Mengel Members: Anthony Jevnikar, David Rush, Denis Glotz, Kim Solez, Marcelo Cantarovich, Mark Haas, Steven Paraskevas Joint Banff/CST Finance Committee
  • 13. Joint Program Structure Banff activies Joint activities CST activities 2015 CST / Banff meeting program Day 1: Monday Day 2: Tuesday Day 3: Wednesday Day 4: Thursday Day 5: Friday Day 6: Saturday Session Potential Banff-premeeting Plenary Session: Progress Report Banff Working groups Joint Pleanary session I: Joint Pleanary session II: Concurrent sessions: Banff meeting summary and CST symposia 08:00 - 08:30 08:30 - 09:00 09:00 - 09:30 09:30 - 10:00 10:00 - 10:30 Coffee break Coffee break Coffee break Coffee break Coffee break Coffee break 10:30 - 11:00 11:00 - 11:30 11:30 - 12:00 12:00 - 01:00 Working Lunch: Banff registration open Working Lunch: Working Lunch: CST registration open Working Lunch: Lunch: Banff adjourns Lunch: Session Potential Banff-premeeting Concurrent Organ Sessions Concurrent sessions: Banff Organ sessions and CST Working groups Concurrent sessions: Banff Organ sessions and CST symposia 01:00 - 01:30 01:30 - 02:00 02:00 - 02:30 02:30 - 03:00 03:00 - 03:30 Coffee break Coffee break Coffee break Coffee break Coffee break Coffee break 03:30 - 04:00 04:00 - 04:30 04:30 - 05:00 05:00 - 05:30 05:30 - 06:00 Events 6:30 Welcome Reception - Cocktails and snacks. Open bar Case presentations from varioous organs with Wine Beer and Food Joint Poster Session with reception CST Awards and Joint CST/Banff Gala Dinner CST President's dinner
  • 14. Target Audience for the 2015 joint CST/Banff meeting: total ~600 expected international delegates • Basic Scientists • Pathologists • Immunogeneticists and HLA experts • Transplant Physicians: Internal Medicine, Surgery, Infectious Diseases, Critical Care • Allied Health Care • Students, Trainees, Fellows