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Atropine Sulfate Injections
Administration
JOANNA BONDOC
U1080511
MAT1008 Presentation 1
Drug Use
• Antimuscarinic
• Indications
Antisialogogue
Bronchial secretion reduction
Prevent cholinergic cardiac effects
Increase ventricular irritability assoc with acute MI and sinus bradycardia
Antidote for
Inadvertent overdose of cholinergic drugs
Cholinesterase poisoning such as organophosphorus insecticides
MAT1008 Presentation 2
Contraindications
• Do NOT administer if patient has:
Severe ulcerative colitis or Toxic megacolon complicating ulcerative colitis
GI obstruction
Closed angle glaucoma
Obstructive uropathy
Myasthenia gravis
MAT1008 Presentation 3
Tachycardia due to cardiac insufficiency
Thyrotoxicosis
Acute haemorrhage with unstable CV status
Fever
Prostate enlargement
Pregnancy induced hypertension
MAT1008 Presentation 4
Interactions
• Other anticholinergics
• Antihistamines, antidepressants, antipsychotic, procainamide,
quinidine, thiazides
• Amantadine
• Digitalis, cholinergics, neostigmine
MAT1008 Presentation 5
Adverse Effects
• CV effects
Tachycardia
Palpitations
• Reduced secretions
• Bronchial plug
• Constipation
• Urinary difficulty
MAT1008 Presentation 6
• Retention
• Mydriasis
• Cyclopegia
• Blurred vision
• Photophobia
• flushed, hot dry skin
MAT1008 Presentation 7
Precautions
• Use with caution
adults over 40 years of age
Pregnant
Children
Lactating
Children with Down syndrome
• Glaucoma risk
• May convert partial organic pyloric stenosis into complete obstruction
MAT1008 Presentation 8
Medication Administration Rights
Critical
Thinking
Medication
Patient
Dose
Route
Time
Refuse
MAT1008 Presentation 9
Conlusion
• Atropine Sulfate Injection is an antimuscurinic drug use for secretion
reduction.
• It is also an antidote for organophosphate poisoning. It is
contraindicated with patients with severe ulcerative colitis, GI
obstruction, glaucoma and pregnancy induced hypertension.
• The side effects are tachycardia, reduced secretion, urinary difficulty,
bronchial plug, photophobia, blurred vision and hot dry skin
• Use with caution to individuals who are over 40 years old, children
with down syndrome, lactating mothers and pregnant women
MAT1008 Presentation 10
Questions
1. Why atropine sulfate injection is needed before an operation
procedure?
2. What are the signs and symptoms to watch out if there is an
adverse effect after administering atropine sulfate?
Email: U1080511@umail.usq.edu.au
MAT1008 Presentation 11
Reference
MAT1008 Presentation 12

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Atropine sulfate injections administration

  • 1. Atropine Sulfate Injections Administration JOANNA BONDOC U1080511 MAT1008 Presentation 1
  • 2. Drug Use • Antimuscarinic • Indications Antisialogogue Bronchial secretion reduction Prevent cholinergic cardiac effects Increase ventricular irritability assoc with acute MI and sinus bradycardia Antidote for Inadvertent overdose of cholinergic drugs Cholinesterase poisoning such as organophosphorus insecticides MAT1008 Presentation 2
  • 3. Contraindications • Do NOT administer if patient has: Severe ulcerative colitis or Toxic megacolon complicating ulcerative colitis GI obstruction Closed angle glaucoma Obstructive uropathy Myasthenia gravis MAT1008 Presentation 3
  • 4. Tachycardia due to cardiac insufficiency Thyrotoxicosis Acute haemorrhage with unstable CV status Fever Prostate enlargement Pregnancy induced hypertension MAT1008 Presentation 4
  • 5. Interactions • Other anticholinergics • Antihistamines, antidepressants, antipsychotic, procainamide, quinidine, thiazides • Amantadine • Digitalis, cholinergics, neostigmine MAT1008 Presentation 5
  • 6. Adverse Effects • CV effects Tachycardia Palpitations • Reduced secretions • Bronchial plug • Constipation • Urinary difficulty MAT1008 Presentation 6
  • 7. • Retention • Mydriasis • Cyclopegia • Blurred vision • Photophobia • flushed, hot dry skin MAT1008 Presentation 7
  • 8. Precautions • Use with caution adults over 40 years of age Pregnant Children Lactating Children with Down syndrome • Glaucoma risk • May convert partial organic pyloric stenosis into complete obstruction MAT1008 Presentation 8
  • 10. Conlusion • Atropine Sulfate Injection is an antimuscurinic drug use for secretion reduction. • It is also an antidote for organophosphate poisoning. It is contraindicated with patients with severe ulcerative colitis, GI obstruction, glaucoma and pregnancy induced hypertension. • The side effects are tachycardia, reduced secretion, urinary difficulty, bronchial plug, photophobia, blurred vision and hot dry skin • Use with caution to individuals who are over 40 years old, children with down syndrome, lactating mothers and pregnant women MAT1008 Presentation 10
  • 11. Questions 1. Why atropine sulfate injection is needed before an operation procedure? 2. What are the signs and symptoms to watch out if there is an adverse effect after administering atropine sulfate? Email: U1080511@umail.usq.edu.au MAT1008 Presentation 11

Notes de l'éditeur

  1. My presentation will be about Atropine Sulfate Injection Medication
  2. Antimuscarinic is an agent that blocks the muscarinic receptors. Antisialogogue is an agent that reduce or stops the flow of saliva
  3. Obstructive Uropathy is a structural or functional interruption of normal urine flow
  4. Tachycardia is fast heartbeat
  5. Anticholinergic is a substance that blocks the neurotransmitter acetylcholine Other anticholinergics May increase vagal blockade Antihistamines, antidepressants, antipsychotic, procainamide, quinidine, thiazides May enhance atropine effects Amantadine Increase toxicity Digitalis, cholinergics, neostigmine Potential adverse effects
  6. Bronchial plug occurs when bronchial secretions accumulate to the point that they obstruct airflow
  7. Mydriasis is the dilation of pupil Cyclopegia is the paralysis of ciliary muscle of eye
  8. Pyloric stenosis is narrowing of the opening from stomach to the first part of small intestine because of pylorus enlargement
  9. Right medication to right patient Dose, Route, Time Patient has the right to refuse
  10. To sum up the atropine sulfate injection administration…
  11. That is the end of my presentation, if you have questions you can rais your hand. If you have none, I will be the one to ask you some questions.
  12. For my reference you can check…