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the

cell

cycle &
division
the cell cycle
Most cells in an organism go through a cycle of growth,
development, and division called the cell cycle.
The cell cycle makes it possible for organisms
to grow and develop
to replace cells that are old or damaged
to produce new cells
the cell cycle
There are two main phases in the cell cycle:
Interphase

Mitotic Phase
phases of the cell cycle
There are two main phases in the cell cycle:

Interphase

Mitotic Phase

Interphase is the period of a cell’s growth and development.
A cell spends most of its life in interphase.
There are three stages of interphase:
rapid growth and replication, or copying, of the
organelles
copying of DNA, the genetic information in a cell
preparation for cell division
phases of the cell cycle
There are two main phases in the cell cycle:
Interphase

Mitotic Phase

A cell reproduces during the mitotic phase.

The mitotic phase has two stages:
Stage 1: the contents of the nucleus divide
Stage 2: the cytoplasm divides
The mitotic phase creates two new identical cells. The original
cell no longer exists.
length of the cell cycle
The time it takes a cell to complete the cell cycle depends on
the type of cell that is dividing.
The cell cycle for some eukaryotic cells might only take eight
minutes, but others can take up to a year.
Most of the cells in the human body can complete the cell
cycle in about 24 hours.
The cells of some organisms divide very quickly. For example,
the fertilized egg of the zebra fish divides into 256 cells in
2.5 hours.
interphase
A new cell begins interphase with a period of rapid growth.
Cellular activities, such as making proteins, follow.
Each cell that is actively dividing eventually copies its DNA and
prepares for cell division.
A cell’s DNA is called chromatin during interphase.
Chromatin is long, thin strands of DNA in the nucleus. If
scientists add dye to a cell in interphase, the nucleus looks like a
plate of spaghetti. This is because the nucleus contains strands
of chromatin tangled together.
phases of interphase
Stage 1: The G1 Stage
This is a period of rapid growth. G1 is the longest stage of the
cell cycle.
During G1, a cell grows and carries out its normal cell functions.
Most cells continue the cell cycle. However, some cells stop the
cell cycle at the G1 stage. Mature nerve cells in your brain remain
in G1 and do not divide again.
phases of interphase
Stage 2: The S Stage
During the S stage, a cell grows and copies its DNA.
Strands of chromatin are copied, so there are now two identical
strands of DNA. This is necessary because each new cell gets a
copy of the genetic information.
The new strands coil up and form chromosomes.
phases of interphase
chromatin to chromosome
phases of interphase
Stage 2: The S Stage
A cell’s DNA is arranged as pairs. Each pair
is called a duplicated chromosome.
Two identical chromosomes called sister
chromatids make up a duplicated
chromosome.
The sister chromatids are held together by
a structure called a centromere.
phases of interphase
Stage 3: The G2 Stage
This is another period of growth and the final preparation for
mitosis.
A cell uses energy to copy DNA during the S stage.
During G2, the cell stores energy that will be used during the
mitotic phase of the cell cycle.
organelle replication
Before a cell divides, it makes a copy of each organelle and they
are distributed between the two new cells. This way, the two new
cells can function properly.
Some organelles, such as the mitochondria and chloroplasts,
have their own DNA. These organelles can make copies of
themselves on their own.
A cell produces other organelles from materials such as proteins
and lipids. A cell makes these materials using the information in
the DNA inside the nucleus.
Organelles are copied during all stages of interphase.
the cell cycle
There are two main phases in the cell cycle:
Interphase

Mitotic Phase
the mitotic phase
The mitotic phase of the cell cycle follows interphase.
There are two stages of the mitotic phase:

Mitosis

Cytokinesis
the mitotic phase
Mitosis

Cytokinesis

During mitosis, the sister chromatids of the
duplicated chromosomes separate from each
other. This gives each daughter cell the same
genetic information.
The contents of the nucleus divide, forming
two identical nuclei.
the mitotic phase
Mitosis

Cytokinesis

For example, a cell that has ten duplicated chromosomes
actually has 20 chromatids. When the cell divides, each
daughter cell will have ten different chromatids.

Chromatids are now called chromosomes.
the mitotic phase
Cytokinesis
Mitosis

During cytokinesis, the cytoplasm divides and two new
daughter cells form.
The organelles that were made during interphase are divided
between the daughter cells.
phases of mitosis
Mitosis, like interphase, is a process that can be divided into
different phases.

Prophase
Metaphase
Anaphase
Telophase
phases of mitosis
Prophase
During the first phase of mitosis, called prophase, the copied
chromatin coils together tightly.
The coils form duplicated chromosomes that can be seen with
a microscope.
The nucleolus disappears and the nuclear membrane breaks
down.
Structures called spindle fibers form in the cytoplasm.
phases of mitosis
Prophase
phases of mitosis
Prophase
Animal

Plant
phases of mitosis
Metaphase
The spindle fibers pull and push the duplicated chromosomes
to the middle of the cell during metaphase.
The chromosomes line up along the middle of the cell. This
makes sure that each new cell will receive one copy of each
chromosome.
Metaphase is the shortest phase in mitosis. It is an important
phase because it makes the new cells the same.
phases of mitosis
Metaphase
phases of mitosis
Metaphase
Animal

Plant
phases of mitosis
Anaphase
In anaphase, the two sister chromatids separate from each
other and are pulled in opposite directions.
Once they are separated, the chromatids are now two identical
single-stranded chromosomes.
As the single-stranded chromosomes move to opposite sides of
the cell, the cell begins to get longer.
Anaphase ends when the two sets of identical chromosomes
reach opposite ends of the cell.
phases of mitosis
Anaphase
phases of mitosis
Anaphase
Animal

Plant
phases of mitosis
Telophase
During telophase, the spindle fibers that helped divide
chromosomes begin to disappear.
The chromosomes begin to uncoil.
A nuclear membrane grows around each set of chromosomes
at either end of the cell.
Two new identical nuclei form.
phases of mitosis
Telophase
phases of mitosis
Telophase
Animal

Plant
dividing the cell’s components
After the last phase of mitosis, the cytoplasm of a cell divides
in a process called cytokinesis.
The specific steps of cytokinesis depend on the type of cell
that is dividing.
dividing the cell’s components

cytokinesis - animal cell
In an animal cell, the cell membrane
contracts, or squeezes together, around
the middle of the cell.
Fibers around the center of the cell pull
together. This forms a crease, called a
furrow, in the middle of the cell. This
furrow gets deeper and deeper until the
cell membrane comes together and
divides the cell.
dividing the cell’s components

cytokinesis - plant cell
Cytokinesis in plant cells is different.
A new cell wall forms in the middle of a plant cell.
Organelles called vesicles join together to form a membranebound disk called
a cell plate.
The cell plate then
grows outward
toward the cell wall
until two new cells
form.
dividing the cell’s components

cytokinesis - plant cell
Cytokinesis in plant cells is different.
A new cell wall forms in the middle of a plant cell.
Organelles called vesicles join together to form a membranebound disk called
a cell plate.
The cell plate then
grows outward
toward the cell wall
until two new cells
form.
dividing the cell’s components

cytokinesis
Animal

Plant
results of cell division
The cell cycle results in two new cells, which are genetically the
same. They also are the same as the original cell that no longer
exists.
A human cell has 46 chromosomes. When that cell divides, it
produces two new cells, each with 46 chromosomes.
The cell cycle is important for reproduction in some organisms.
It is important for growth in multicellular organisms.
The cell cycle also helps replace worn-out or damaged cells
and repair damaged tissues.
results of cell division
growth

Cell division allows multicellular organisms, such as humans, to
grow and develop from one cell (a fertilized egg).
In humans, cell division begins about 24 hours after
fertilization and continues quickly for the first few years of life.
During the next few years, you will probably go through a
period of rapid growth and development.
This happens because cells divide and
increase in number as you grow and
develop.
results of cell division

small elephants grow to large
elephants through mitosis.
results of cell division
replacement

Cell division continues even after an organism is fully grown.
Cell division replaces cells that wear out or are damaged.
The outermost layer of your skin is always rubbing or flaking
off. A layer of cells below the skin’s surface is constantly
dividing.
This produces millions of new cells each day to replace the
ones that rub off.
Everyday billions of red blood cells die and need to be
replaced.
results of cell division
repair

Cell division is also important for repairing damage.
When a bone breaks, cell division produces new bone cells.
These new cells patch the broken pieces of bone back
together.
Not all damage can be repaired. This is because not all cells
continue to divide. Some nerve cells stop the cell cycle in
interphase. Injuries to nerve cells often cause permanent
damage.
The Cell Cycle & Division: Understanding the Stages of Growth, DNA Replication, Mitosis and Cytokinesis

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The Cell Cycle & Division: Understanding the Stages of Growth, DNA Replication, Mitosis and Cytokinesis

  • 2. the cell cycle Most cells in an organism go through a cycle of growth, development, and division called the cell cycle. The cell cycle makes it possible for organisms to grow and develop to replace cells that are old or damaged to produce new cells
  • 3. the cell cycle There are two main phases in the cell cycle: Interphase Mitotic Phase
  • 4. phases of the cell cycle There are two main phases in the cell cycle: Interphase Mitotic Phase Interphase is the period of a cell’s growth and development. A cell spends most of its life in interphase. There are three stages of interphase: rapid growth and replication, or copying, of the organelles copying of DNA, the genetic information in a cell preparation for cell division
  • 5. phases of the cell cycle There are two main phases in the cell cycle: Interphase Mitotic Phase A cell reproduces during the mitotic phase. The mitotic phase has two stages: Stage 1: the contents of the nucleus divide Stage 2: the cytoplasm divides The mitotic phase creates two new identical cells. The original cell no longer exists.
  • 6. length of the cell cycle The time it takes a cell to complete the cell cycle depends on the type of cell that is dividing. The cell cycle for some eukaryotic cells might only take eight minutes, but others can take up to a year. Most of the cells in the human body can complete the cell cycle in about 24 hours. The cells of some organisms divide very quickly. For example, the fertilized egg of the zebra fish divides into 256 cells in 2.5 hours.
  • 7. interphase A new cell begins interphase with a period of rapid growth. Cellular activities, such as making proteins, follow. Each cell that is actively dividing eventually copies its DNA and prepares for cell division. A cell’s DNA is called chromatin during interphase. Chromatin is long, thin strands of DNA in the nucleus. If scientists add dye to a cell in interphase, the nucleus looks like a plate of spaghetti. This is because the nucleus contains strands of chromatin tangled together.
  • 8. phases of interphase Stage 1: The G1 Stage This is a period of rapid growth. G1 is the longest stage of the cell cycle. During G1, a cell grows and carries out its normal cell functions. Most cells continue the cell cycle. However, some cells stop the cell cycle at the G1 stage. Mature nerve cells in your brain remain in G1 and do not divide again.
  • 9. phases of interphase Stage 2: The S Stage During the S stage, a cell grows and copies its DNA. Strands of chromatin are copied, so there are now two identical strands of DNA. This is necessary because each new cell gets a copy of the genetic information. The new strands coil up and form chromosomes.
  • 11. phases of interphase Stage 2: The S Stage A cell’s DNA is arranged as pairs. Each pair is called a duplicated chromosome. Two identical chromosomes called sister chromatids make up a duplicated chromosome. The sister chromatids are held together by a structure called a centromere.
  • 12. phases of interphase Stage 3: The G2 Stage This is another period of growth and the final preparation for mitosis. A cell uses energy to copy DNA during the S stage. During G2, the cell stores energy that will be used during the mitotic phase of the cell cycle.
  • 13. organelle replication Before a cell divides, it makes a copy of each organelle and they are distributed between the two new cells. This way, the two new cells can function properly. Some organelles, such as the mitochondria and chloroplasts, have their own DNA. These organelles can make copies of themselves on their own. A cell produces other organelles from materials such as proteins and lipids. A cell makes these materials using the information in the DNA inside the nucleus. Organelles are copied during all stages of interphase.
  • 14. the cell cycle There are two main phases in the cell cycle: Interphase Mitotic Phase
  • 15. the mitotic phase The mitotic phase of the cell cycle follows interphase. There are two stages of the mitotic phase: Mitosis Cytokinesis
  • 16. the mitotic phase Mitosis Cytokinesis During mitosis, the sister chromatids of the duplicated chromosomes separate from each other. This gives each daughter cell the same genetic information. The contents of the nucleus divide, forming two identical nuclei.
  • 17. the mitotic phase Mitosis Cytokinesis For example, a cell that has ten duplicated chromosomes actually has 20 chromatids. When the cell divides, each daughter cell will have ten different chromatids. Chromatids are now called chromosomes.
  • 18. the mitotic phase Cytokinesis Mitosis During cytokinesis, the cytoplasm divides and two new daughter cells form. The organelles that were made during interphase are divided between the daughter cells.
  • 19.
  • 20. phases of mitosis Mitosis, like interphase, is a process that can be divided into different phases. Prophase Metaphase Anaphase Telophase
  • 21. phases of mitosis Prophase During the first phase of mitosis, called prophase, the copied chromatin coils together tightly. The coils form duplicated chromosomes that can be seen with a microscope. The nucleolus disappears and the nuclear membrane breaks down. Structures called spindle fibers form in the cytoplasm.
  • 24. phases of mitosis Metaphase The spindle fibers pull and push the duplicated chromosomes to the middle of the cell during metaphase. The chromosomes line up along the middle of the cell. This makes sure that each new cell will receive one copy of each chromosome. Metaphase is the shortest phase in mitosis. It is an important phase because it makes the new cells the same.
  • 27. phases of mitosis Anaphase In anaphase, the two sister chromatids separate from each other and are pulled in opposite directions. Once they are separated, the chromatids are now two identical single-stranded chromosomes. As the single-stranded chromosomes move to opposite sides of the cell, the cell begins to get longer. Anaphase ends when the two sets of identical chromosomes reach opposite ends of the cell.
  • 30. phases of mitosis Telophase During telophase, the spindle fibers that helped divide chromosomes begin to disappear. The chromosomes begin to uncoil. A nuclear membrane grows around each set of chromosomes at either end of the cell. Two new identical nuclei form.
  • 33. dividing the cell’s components After the last phase of mitosis, the cytoplasm of a cell divides in a process called cytokinesis. The specific steps of cytokinesis depend on the type of cell that is dividing.
  • 34. dividing the cell’s components cytokinesis - animal cell In an animal cell, the cell membrane contracts, or squeezes together, around the middle of the cell. Fibers around the center of the cell pull together. This forms a crease, called a furrow, in the middle of the cell. This furrow gets deeper and deeper until the cell membrane comes together and divides the cell.
  • 35. dividing the cell’s components cytokinesis - plant cell Cytokinesis in plant cells is different. A new cell wall forms in the middle of a plant cell. Organelles called vesicles join together to form a membranebound disk called a cell plate. The cell plate then grows outward toward the cell wall until two new cells form.
  • 36. dividing the cell’s components cytokinesis - plant cell Cytokinesis in plant cells is different. A new cell wall forms in the middle of a plant cell. Organelles called vesicles join together to form a membranebound disk called a cell plate. The cell plate then grows outward toward the cell wall until two new cells form.
  • 37. dividing the cell’s components cytokinesis Animal Plant
  • 38.
  • 39. results of cell division The cell cycle results in two new cells, which are genetically the same. They also are the same as the original cell that no longer exists. A human cell has 46 chromosomes. When that cell divides, it produces two new cells, each with 46 chromosomes. The cell cycle is important for reproduction in some organisms. It is important for growth in multicellular organisms. The cell cycle also helps replace worn-out or damaged cells and repair damaged tissues.
  • 40. results of cell division growth Cell division allows multicellular organisms, such as humans, to grow and develop from one cell (a fertilized egg). In humans, cell division begins about 24 hours after fertilization and continues quickly for the first few years of life. During the next few years, you will probably go through a period of rapid growth and development. This happens because cells divide and increase in number as you grow and develop.
  • 41. results of cell division small elephants grow to large elephants through mitosis.
  • 42. results of cell division replacement Cell division continues even after an organism is fully grown. Cell division replaces cells that wear out or are damaged. The outermost layer of your skin is always rubbing or flaking off. A layer of cells below the skin’s surface is constantly dividing. This produces millions of new cells each day to replace the ones that rub off. Everyday billions of red blood cells die and need to be replaced.
  • 43. results of cell division repair Cell division is also important for repairing damage. When a bone breaks, cell division produces new bone cells. These new cells patch the broken pieces of bone back together. Not all damage can be repaired. This is because not all cells continue to divide. Some nerve cells stop the cell cycle in interphase. Injuries to nerve cells often cause permanent damage.