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Advances in Genetics
Heredity - Section 5.3
Bizarre examples of
genetic engineering
Genetic Engineering
Genetic engineering is a laboratory technique used by
scientists to change the DNA of living organisms.
Where is genetic engineering used?
      To help produce large volumes of medicine.
      Change how cells perform their normal functions.
      Create plants that are resistant to disease
Recombinant DNA
Producing recombinant DNA is one type of genetic
engineering.
Recombinant DNA is made by inserting a useful segment
of DNA from one organism into a bacterium.
The bacterium then reproduces itself and also the
recombinant DNA.
This method is used to produce large quantities of
human insulin, human growth hormone, and other
chemicals by bacteria.
Recombinant DNA




DNA LOOP – A piece of double-stranded DNA. It carries genes that
are not essential to the bacteria, but can help a bacteria survive in
certain circumstances.
Gene Therapy
Another form of genetic engineering is gene transfer
(gene therapy).
The goal is to replace abnormal genetic material with
normal genetic material.
Gene therapy may help with genetic disorders, such a
cystic fibrosis.
Normal DNA or RNA is placed in a virus, the virus then
delivers the normal DNA or RNA to target cells.
Gene Therapy
Gene Therapy
Gene Therapy
  learn.genetics.com




                 Already completed Section 1 in 5.2
                 Do Section 2 and part of 3 together
                 Students do Section 4 and 5 on own
Selective Breeding
Selective breeding is the process of breeding plants and
animals for particular traits.
Selective Breeding



A farmer wants to breed a variety of cow that produces a lot of
milk, the farmer will then identify the cows that produce the
most milk and allow them to breed with one another. Repeat the
process as many times as necessary by allowing the offspring to
reproduce with another until desired goal has been achieved.
Selective Breeding
Dogs are another good example of selective breeding.

Gamekeepers who hunted birds for leisure in the 1800s wanted
a dog that didn’t actually exist so they selectively breed a
mastiff and a bulldog to get the qualities that they wanted.
Mastiffs were big and strong who were also good companions
but they lacked in speed and aggression. The bulldog however
was aggressive and fast but lacked in strength. The selective
breeding process eventually produced a bullmastiff which was
large, quick, strong and aggressive.
Selective Breeding
                  bulldog


              +

mastiff


          =                 bullmastiff
Selective Breeding




         http://www.pbs.org/wgbh/harvest/engineer/select.html
Genetically engineered
Breeding


         http://www.pbs.org/wgbh/harvest/etc/video.html
Genetically Engineered
Plants
Genetic engineering can produce improvements in crop
plants (corn, wheat, rice).
You select a gene that produces a desired trait in one
plant and then insert that gene(s) into a different
plant.
Genetically Engineered
Plants
Genetically Engineered
Plants



         http://www.pbs.org/wgbh/harvest/coming/coming.html
Stem Cells
                  learn.genetics.com

The Nature of Stem Cells video - watch together
Unlocking the Stem Cell Potential - video - watch together
Go, Go Stems Cells - students must choose 3 types of cells and answer
various questions (where are the stem cells located for this tissue?)
Stem Cell Quick Reference - students do on own with worksheet
The Stem Cell Debate - students do on own with worksheet
Stem Cells
Stem Cells
Cloning
                      learn.genetics.com

Click and Clone - online lab - students do on own
Is it cloning or not - online quiz
Why Clone - students do on own with worksheet
What are the Risks of Cloning? - students do on own with worksheet
What are some Issues in Cloning? - discuss as a class

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Advances in Genetics (5.3)

  • 3. Genetic Engineering Genetic engineering is a laboratory technique used by scientists to change the DNA of living organisms. Where is genetic engineering used? To help produce large volumes of medicine. Change how cells perform their normal functions. Create plants that are resistant to disease
  • 4. Recombinant DNA Producing recombinant DNA is one type of genetic engineering. Recombinant DNA is made by inserting a useful segment of DNA from one organism into a bacterium. The bacterium then reproduces itself and also the recombinant DNA. This method is used to produce large quantities of human insulin, human growth hormone, and other chemicals by bacteria.
  • 5. Recombinant DNA DNA LOOP – A piece of double-stranded DNA. It carries genes that are not essential to the bacteria, but can help a bacteria survive in certain circumstances.
  • 6.
  • 7. Gene Therapy Another form of genetic engineering is gene transfer (gene therapy). The goal is to replace abnormal genetic material with normal genetic material. Gene therapy may help with genetic disorders, such a cystic fibrosis. Normal DNA or RNA is placed in a virus, the virus then delivers the normal DNA or RNA to target cells.
  • 10. Gene Therapy learn.genetics.com Already completed Section 1 in 5.2 Do Section 2 and part of 3 together Students do Section 4 and 5 on own
  • 11. Selective Breeding Selective breeding is the process of breeding plants and animals for particular traits.
  • 12. Selective Breeding A farmer wants to breed a variety of cow that produces a lot of milk, the farmer will then identify the cows that produce the most milk and allow them to breed with one another. Repeat the process as many times as necessary by allowing the offspring to reproduce with another until desired goal has been achieved.
  • 13. Selective Breeding Dogs are another good example of selective breeding. Gamekeepers who hunted birds for leisure in the 1800s wanted a dog that didn’t actually exist so they selectively breed a mastiff and a bulldog to get the qualities that they wanted. Mastiffs were big and strong who were also good companions but they lacked in speed and aggression. The bulldog however was aggressive and fast but lacked in strength. The selective breeding process eventually produced a bullmastiff which was large, quick, strong and aggressive.
  • 14. Selective Breeding bulldog + mastiff = bullmastiff
  • 15. Selective Breeding http://www.pbs.org/wgbh/harvest/engineer/select.html
  • 16. Genetically engineered Breeding http://www.pbs.org/wgbh/harvest/etc/video.html
  • 17. Genetically Engineered Plants Genetic engineering can produce improvements in crop plants (corn, wheat, rice). You select a gene that produces a desired trait in one plant and then insert that gene(s) into a different plant.
  • 19. Genetically Engineered Plants http://www.pbs.org/wgbh/harvest/coming/coming.html
  • 20. Stem Cells learn.genetics.com The Nature of Stem Cells video - watch together Unlocking the Stem Cell Potential - video - watch together Go, Go Stems Cells - students must choose 3 types of cells and answer various questions (where are the stem cells located for this tissue?) Stem Cell Quick Reference - students do on own with worksheet The Stem Cell Debate - students do on own with worksheet
  • 21.
  • 24. Cloning learn.genetics.com Click and Clone - online lab - students do on own Is it cloning or not - online quiz Why Clone - students do on own with worksheet What are the Risks of Cloning? - students do on own with worksheet What are some Issues in Cloning? - discuss as a class