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Essential Questions
 What are the functions of the urinary system?
 What are some disorders of the urinary system?
 How are disorders of the urinary system treated?
 How do you relate the body’s hormone control to
the urinary system?
4.02 Understand the functions and disorders of the urinary system
2
Functions:
 Excretion
 Formation of urine
 Fluid and electrolyte balance
 Elimination of urine
4.02 Understand the functions and disorders of the urinary system
3
Functions:
 Excretion
 Formation of urine
 Fluid and electrolyte balance
 Elimination of urine
4.02 Understand the functions and disorders of the urinary system
4
Excretion
 What is excretion?
 Why does the body have excretory functions?
 What is the composition of wastes excreted by
the urinary system?
 How is it relevant to health?
4.02 Understand the functions and disorders of the urinary system
5
Filtration
Reabsorption
Secretion
4.02 Understand the functions and disorders of the urinary system
6
4.02 Understand the functions and disorders of the urinary system
• Blood from renal
artery enters
glomerulus
• High pressure in
glomerulus forces
fluid into Bowman’s
capsule, where it is
filtered
7
BOWMAN’S CAPSULE
 Bowman’s capsule filters out 125cc of fluid/min.
…how many cc’s per hour is this?
4.02 Understand the functions and disorders of the urinary system
8
 What substances are reabsorbed?
 Where do they go?
 If blood levels of certain substances are high, the
substances will not be reabsorbed.
4.02 Understand the functions and disorders of the urinary system
9
4.02 Understand the functions and disorders of the urinary system
What is secretion?
Describe how this
process is the opposite
of reabsorption….
10
 What substances are secreted into the
collecting tubules?
4.02 Understand the functions and disorders of the urinary system
11
Fluid and electrolyte balance
 Electrolytes are selectively secreted to maintain
body’s acid-base balance.
• What are electrolytes?
• What do they do?
4.02 Understand the functions and disorders of the urinary system
12
Fluid and electrolyte balance
Chemical control
• ADH
• Aldosterone
Nervous control
4.02 Understand the functions and disorders of the urinary system
13
Fluid and electrolyte balance
Chemical control
 The regulation & secretion of ADH is under
the control of the hypothalamus
 ADH is actually secreted from the posterior
pituitary gland
 What is the function of
ADH (antidiuretic hormone)?
4.02 Understand the functions and disorders of the urinary system
14
Fluid and electrolyte balance
Chemical control
 The amount of ADH produced is related to the
level of body hydration
 What factors regulate the release of ADH?
4.02 Understand the functions and disorders of the urinary system
15
Forming more dilute urine:
 What are diuretics?
 What effect do they have on the production of
urine?
 Give examples of substances that have diuretic
effects.
4.02 Understand the functions and disorders of the urinary system
16
Fluid and electrolyte balance
Chemical control
Aldosterone
 Where does it come from?
 What does it do?
 Aldosterone release is the result of the renin-
angiotensin system. What does this mean?
4.02 Understand the functions and disorders of the urinary system
17
Fluid and electrolyte balance
4.02 Understand the functions and disorders of the urinary system
What effect does this cycle have on your blood pressure?
18
Fluid and electrolyte balance
Nervous control
 How does the nervous system
control urinary secretions?
 What other systems are involved in
the production and excretion of
urine?
4.02 Understand the functions and disorders of the urinary system
19
4.02 Understand the functions and disorders of the urinary system
Review urine formation, electrolyte exchange,
and some factors that effect urine volume.
20
 What do you predict will happen to blood
pressure when the blood volume increases?
 What if blood
volume decreases?
4.02 Understand the functions and disorders of the urinary system
21
 If more water is reabsorbed back into the
body---what will happen to urine
concentration?
 (more or less concentrated?)
4.02 Understand the functions and disorders of the urinary system
22
Elimination of urine
What causes the bladder to empty?
Is this a voluntary or involuntary action?
4.02 Understand the functions and disorders of the urinary system
23
Elimination of urine
Urinary output
4.02 Understand the functions and disorders of the urinary system
Average urinary output = 1500 ml per day
What effects the
color of your
urine?
24
An examination of urine
 What does normal urine look like?
 What constitutes an abnormal urinalysis?
4.02 Understand the functions and disorders of the urinary system
25
4.02 Understand the functions and disorders of the urinary system
26
4.02 Understand the functions and disorders of the urinary system
27
Cystitis
 What is cystitis
(cyst= medical term for ____ +itis =___ )
Most common cause: E. Coli
What are the major symptoms of cystitis?
4.02 Understand the functions and disorders of the urinary system
28
Cystitis
 More common in females—Why ??
4.02 Understand the functions and disorders of the urinary system
29
Glomerulonephritis
4.02 Understand the functions and disorders of the urinary system
Disease which
injures the
glomerulus.
What will happen
as a result of
damaged
glomeruli?
30
Glomerulonephritis
 Two types:
• Acute
• Chronic
 What is the prognosis for each?
4.02 Understand the functions and disorders of the urinary system
31
Renal calculi (Kidney stones)
Also known as nephrolithiasis
nephro lith iasis
What are renal calculi made of?
What are the symptoms?
4.02 Understand the functions and disorders of the urinary system
32
Renal calculi
 What will happen if
the ureters are
blocked?
4.02 Understand the functions and disorders of the urinary system
33
Renal calculi
How is it treated?
4.02 Understand the functions and disorders of the urinary system
34
Renal calculi
How does lithotripsy work?
4.02 Understand the functions and disorders of the urinary system
35
Renal failure
Acute
• What causes it?
• What are the symptoms?
4.02 Understand the functions and disorders of the urinary system
36
Renal failure
chronic
May be none in early stages, urinalysis
may reveal proteinuria
Why would protein be present in the
urine?
Why is this not normal?
4.02 Understand the functions and disorders of the urinary system
37
Renal Failure
 Chronic kidney
disease leads to a
buildup of fluid and
waste products in
the body.
4.02 Understand the functions and disorders of the urinary system
38
Renal Failure
 How is it treated?
• Peritoneal dialysis
• What is the process
involved in this
treatment?
4.02 Understand the functions and disorders of the urinary system
39
Renal Failure
 How is it treated?
• Hemodialysis
• What is
hemodialysis?
4.02 Understand the functions and disorders of the urinary system
40
Renal Failure
Compare the treatment of acute and
chronic renal failure.
4.02 Understand the functions and disorders of the urinary system
41
How does hemodialysis mimic
glomerular function?
4.02 Understand the functions and disorders of the urinary system
42
Renal transplant
 What is involved in this treatment option?
 When does a patient get a transplant?
4.02 Understand the functions and disorders of the urinary system
43
Renal transplant
4.02 Understand the functions and disorders of the urinary system
What is the
major
complication of
renal
transplantation?
44
 Essential Questions
 What are the functions of the urinary system?
 What are some disorders of the urinary system?
 How are disorders of the urinary system treated?
 How do you relate the body’s hormone control to
the urinary system?
4.02 Understand the functions and disorders of the urinary system
45

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Functions and Disorders of Urinary System

  • 1.
  • 2. Essential Questions  What are the functions of the urinary system?  What are some disorders of the urinary system?  How are disorders of the urinary system treated?  How do you relate the body’s hormone control to the urinary system? 4.02 Understand the functions and disorders of the urinary system 2
  • 3. Functions:  Excretion  Formation of urine  Fluid and electrolyte balance  Elimination of urine 4.02 Understand the functions and disorders of the urinary system 3
  • 4. Functions:  Excretion  Formation of urine  Fluid and electrolyte balance  Elimination of urine 4.02 Understand the functions and disorders of the urinary system 4
  • 5. Excretion  What is excretion?  Why does the body have excretory functions?  What is the composition of wastes excreted by the urinary system?  How is it relevant to health? 4.02 Understand the functions and disorders of the urinary system 5
  • 6. Filtration Reabsorption Secretion 4.02 Understand the functions and disorders of the urinary system 6
  • 7. 4.02 Understand the functions and disorders of the urinary system • Blood from renal artery enters glomerulus • High pressure in glomerulus forces fluid into Bowman’s capsule, where it is filtered 7
  • 8. BOWMAN’S CAPSULE  Bowman’s capsule filters out 125cc of fluid/min. …how many cc’s per hour is this? 4.02 Understand the functions and disorders of the urinary system 8
  • 9.  What substances are reabsorbed?  Where do they go?  If blood levels of certain substances are high, the substances will not be reabsorbed. 4.02 Understand the functions and disorders of the urinary system 9
  • 10. 4.02 Understand the functions and disorders of the urinary system What is secretion? Describe how this process is the opposite of reabsorption…. 10
  • 11.  What substances are secreted into the collecting tubules? 4.02 Understand the functions and disorders of the urinary system 11
  • 12. Fluid and electrolyte balance  Electrolytes are selectively secreted to maintain body’s acid-base balance. • What are electrolytes? • What do they do? 4.02 Understand the functions and disorders of the urinary system 12
  • 13. Fluid and electrolyte balance Chemical control • ADH • Aldosterone Nervous control 4.02 Understand the functions and disorders of the urinary system 13
  • 14. Fluid and electrolyte balance Chemical control  The regulation & secretion of ADH is under the control of the hypothalamus  ADH is actually secreted from the posterior pituitary gland  What is the function of ADH (antidiuretic hormone)? 4.02 Understand the functions and disorders of the urinary system 14
  • 15. Fluid and electrolyte balance Chemical control  The amount of ADH produced is related to the level of body hydration  What factors regulate the release of ADH? 4.02 Understand the functions and disorders of the urinary system 15
  • 16. Forming more dilute urine:  What are diuretics?  What effect do they have on the production of urine?  Give examples of substances that have diuretic effects. 4.02 Understand the functions and disorders of the urinary system 16
  • 17. Fluid and electrolyte balance Chemical control Aldosterone  Where does it come from?  What does it do?  Aldosterone release is the result of the renin- angiotensin system. What does this mean? 4.02 Understand the functions and disorders of the urinary system 17
  • 18. Fluid and electrolyte balance 4.02 Understand the functions and disorders of the urinary system What effect does this cycle have on your blood pressure? 18
  • 19. Fluid and electrolyte balance Nervous control  How does the nervous system control urinary secretions?  What other systems are involved in the production and excretion of urine? 4.02 Understand the functions and disorders of the urinary system 19
  • 20. 4.02 Understand the functions and disorders of the urinary system Review urine formation, electrolyte exchange, and some factors that effect urine volume. 20
  • 21.  What do you predict will happen to blood pressure when the blood volume increases?  What if blood volume decreases? 4.02 Understand the functions and disorders of the urinary system 21
  • 22.  If more water is reabsorbed back into the body---what will happen to urine concentration?  (more or less concentrated?) 4.02 Understand the functions and disorders of the urinary system 22
  • 23. Elimination of urine What causes the bladder to empty? Is this a voluntary or involuntary action? 4.02 Understand the functions and disorders of the urinary system 23
  • 24. Elimination of urine Urinary output 4.02 Understand the functions and disorders of the urinary system Average urinary output = 1500 ml per day What effects the color of your urine? 24
  • 25. An examination of urine  What does normal urine look like?  What constitutes an abnormal urinalysis? 4.02 Understand the functions and disorders of the urinary system 25
  • 26. 4.02 Understand the functions and disorders of the urinary system 26
  • 27. 4.02 Understand the functions and disorders of the urinary system 27
  • 28. Cystitis  What is cystitis (cyst= medical term for ____ +itis =___ ) Most common cause: E. Coli What are the major symptoms of cystitis? 4.02 Understand the functions and disorders of the urinary system 28
  • 29. Cystitis  More common in females—Why ?? 4.02 Understand the functions and disorders of the urinary system 29
  • 30. Glomerulonephritis 4.02 Understand the functions and disorders of the urinary system Disease which injures the glomerulus. What will happen as a result of damaged glomeruli? 30
  • 31. Glomerulonephritis  Two types: • Acute • Chronic  What is the prognosis for each? 4.02 Understand the functions and disorders of the urinary system 31
  • 32. Renal calculi (Kidney stones) Also known as nephrolithiasis nephro lith iasis What are renal calculi made of? What are the symptoms? 4.02 Understand the functions and disorders of the urinary system 32
  • 33. Renal calculi  What will happen if the ureters are blocked? 4.02 Understand the functions and disorders of the urinary system 33
  • 34. Renal calculi How is it treated? 4.02 Understand the functions and disorders of the urinary system 34
  • 35. Renal calculi How does lithotripsy work? 4.02 Understand the functions and disorders of the urinary system 35
  • 36. Renal failure Acute • What causes it? • What are the symptoms? 4.02 Understand the functions and disorders of the urinary system 36
  • 37. Renal failure chronic May be none in early stages, urinalysis may reveal proteinuria Why would protein be present in the urine? Why is this not normal? 4.02 Understand the functions and disorders of the urinary system 37
  • 38. Renal Failure  Chronic kidney disease leads to a buildup of fluid and waste products in the body. 4.02 Understand the functions and disorders of the urinary system 38
  • 39. Renal Failure  How is it treated? • Peritoneal dialysis • What is the process involved in this treatment? 4.02 Understand the functions and disorders of the urinary system 39
  • 40. Renal Failure  How is it treated? • Hemodialysis • What is hemodialysis? 4.02 Understand the functions and disorders of the urinary system 40
  • 41. Renal Failure Compare the treatment of acute and chronic renal failure. 4.02 Understand the functions and disorders of the urinary system 41
  • 42. How does hemodialysis mimic glomerular function? 4.02 Understand the functions and disorders of the urinary system 42
  • 43. Renal transplant  What is involved in this treatment option?  When does a patient get a transplant? 4.02 Understand the functions and disorders of the urinary system 43
  • 44. Renal transplant 4.02 Understand the functions and disorders of the urinary system What is the major complication of renal transplantation? 44
  • 45.  Essential Questions  What are the functions of the urinary system?  What are some disorders of the urinary system?  How are disorders of the urinary system treated?  How do you relate the body’s hormone control to the urinary system? 4.02 Understand the functions and disorders of the urinary system 45

Notes de l'éditeur

  1. Excretion is the removal of waste from a cell.
  2. The kidney nephrons form urine in three processes: filtration (glomerulus),reabsorption (within renaltubules), and secretion ( by the tubular cells)
  3. Page 430 in text
  4. 7500 mL180 liters in 24 hours
  5. Water glucose amino acids vitamins bicarbonate ions and the chloride salts of calcium sodium potassium and magnesium are resbsorbedGo back into the blood stream
  6. This process secretes substances from the blood into the peritubular capillaries into the urine in the distal and collecting tubules
  7. Ammonia creatinine, hydrogen ions, potassium, and some drugs
  8. Electrically charged particles in a solutionMaintain acid base balance
  9. ADH helps to increase the size of the cell membrane pores in the epithelial cells of the distal tubule and collecting ducts by increasing their permeability to water
  10. Increase in osmotic pressure of the blood will trigger ADH to be released. ADH will inhibit normal urine formation and water may be held in the tissues
  11. Diuretics increase urinary output by inhibiting the reabsorption of waterAlcohol and caffeine are examples of diuretics
  12. Secreted from adrenal cortexPromotes the excretion of potassium and hydrogen ions and the reabsorption of sodium ions. Also chloride ions and water are absorbedAs blood passes through the glomerulus to the Bowmans capsule specialized cells can detect a drop in blood pressure. A hormone called Renin is released by the kidneys into the bloodstream. Renin stimulates the release the release of aldosterone from the adrenal cortex and restricts the blood vessels
  13. Increase blood pressure
  14. Completed directly through the action of nerve impulses on the blood vessels leading to the kidney and on those within the kidney leading to the glomerulus.Indirect nerve control is achieved through the stimulation of certain endocrine glands. Hormones will control urinary secretion.
  15. Internal urinary sphincter is involuntary muscle and keeps the urethra closed External urinary sphincter is voluntary muscle.
  16. Page 433 in text
  17. Inflammation of the mucous membrane lining of the urinary bladder. E. coli is normally found in the rectums/s dysuriapolyuria (frequent urination)
  18. Inflammation of the glomerulus of the nephronThe filtration process is affected. Plama proteins are filtered through and protein will be found in the urine and also RBCs will be present (hematuria)
  19. Acute= short termChronic= long lasting and will result in kidney failure
  20. Calcium phosphate and uric acidExtreme pain is usually first signNausea and vomiting BurningFrequent urge to peeChills FeverWeaknessHematuria
  21. Hydronephrosis- fluid gets backed up
  22. Increase in fluid intake to help flush out the stoneMeds to dissolve the stone
  23. Shockwaves help to break down the stones. The stones become sandlike and then can be passed through the urinary system
  24. Occurs suddenly Causes may be from nephritis (inflammation of the nephron), shock, bleeding, sudden heart failure, or poisoningS/S-oliguria or anuria, Uremia can happen due to anuria. s/s of uremia is headaches, dyspnea, nausea, vomitting, and in extreme cases coma and death
  25. A gradual loss of kidney functionProtein should not be able to pass through the capillary membranes of the glomerulus.
  26. This uses the person’s own peritoneal lining instead of a dialyzer to filter the blood. A cleansing solution called dialysate travels through a catheter implanted into the abdomen. Fluids, wastes, electrolytes, and chemicals pass from the tiny blood vessels in the peritoneal membrane into the dialysate. After several hours, the dialysate is drained from the abdomen which takes the wastes from the blood with it. The abdomen is filled with fresh dialysate and the cleaning process begins again. The most common type of peritoneal dialysis is called Continous ambulatory peritoneal dialysis (CAPD). The dialysate solutions stays in the abdomen for 4 to 6 hours. The process of draining the dialysate and replacing it with fresh solution takes about 30 minutes. Most people change the solution four times a day.Automated peritoneal dialysis is performed overnight while the client sleeps. It usually takes 6-8 hours.Complication is peritonitis (inflammation of the peritoneal lining)
  27. Hemodialysis is a process for purifying blood by passing it through thin membranes and exposing it to a solution which continually circulates around the membrane. Substances in the blood pass through the membranes to the lesser concentrated dialysate. The part of the unit that actually substitutes for the kidney is a glass tube called a dialyzer which is filled with thousands of minute hollow fibers attached firmly at both ends. Blood from the client flows through the fibers which are surrounded by circulating dialysate. The dialysate is customized for each patient with appropriate levels of sodium, bicarbonate and other substances. These cross the membrane and enter the blood. At the same time, extra water and waste products leave the blood to enter the dialysate. A fistula which is an opening between an artery and a vein or a graft which is a vein inserted between an artery and a vein is surgically constructed (lasts 3-5 years) This provides a site for the needle to be inserted for dialysis. 2 to 3 x a week and each tx takes 2-4 hours.
  28. Kidney transplant is done in cases of prolonged chronic renal failure involving both kidneys. Usually the person will be on dialysis for a long time awaiting a compatible organ.The kidney can come from a living donor or post mortem donor. Blood and other cellular material must match in order to ensure the greatest potential for a successful transplant
  29. Rejection of the kidney Meds will be taken every day to prevent rejection.