Beyond the EU: DORA and NIS 2 Directive's Global Impact
Functions and Disorders of Urinary System
1.
2. Essential Questions
What are the functions of the urinary system?
What are some disorders of the urinary system?
How are disorders of the urinary system treated?
How do you relate the body’s hormone control to
the urinary system?
4.02 Understand the functions and disorders of the urinary system
2
3. Functions:
Excretion
Formation of urine
Fluid and electrolyte balance
Elimination of urine
4.02 Understand the functions and disorders of the urinary system
3
4. Functions:
Excretion
Formation of urine
Fluid and electrolyte balance
Elimination of urine
4.02 Understand the functions and disorders of the urinary system
4
5. Excretion
What is excretion?
Why does the body have excretory functions?
What is the composition of wastes excreted by
the urinary system?
How is it relevant to health?
4.02 Understand the functions and disorders of the urinary system
5
7. 4.02 Understand the functions and disorders of the urinary system
• Blood from renal
artery enters
glomerulus
• High pressure in
glomerulus forces
fluid into Bowman’s
capsule, where it is
filtered
7
8. BOWMAN’S CAPSULE
Bowman’s capsule filters out 125cc of fluid/min.
…how many cc’s per hour is this?
4.02 Understand the functions and disorders of the urinary system
8
9. What substances are reabsorbed?
Where do they go?
If blood levels of certain substances are high, the
substances will not be reabsorbed.
4.02 Understand the functions and disorders of the urinary system
9
10. 4.02 Understand the functions and disorders of the urinary system
What is secretion?
Describe how this
process is the opposite
of reabsorption….
10
11. What substances are secreted into the
collecting tubules?
4.02 Understand the functions and disorders of the urinary system
11
12. Fluid and electrolyte balance
Electrolytes are selectively secreted to maintain
body’s acid-base balance.
• What are electrolytes?
• What do they do?
4.02 Understand the functions and disorders of the urinary system
12
13. Fluid and electrolyte balance
Chemical control
• ADH
• Aldosterone
Nervous control
4.02 Understand the functions and disorders of the urinary system
13
14. Fluid and electrolyte balance
Chemical control
The regulation & secretion of ADH is under
the control of the hypothalamus
ADH is actually secreted from the posterior
pituitary gland
What is the function of
ADH (antidiuretic hormone)?
4.02 Understand the functions and disorders of the urinary system
14
15. Fluid and electrolyte balance
Chemical control
The amount of ADH produced is related to the
level of body hydration
What factors regulate the release of ADH?
4.02 Understand the functions and disorders of the urinary system
15
16. Forming more dilute urine:
What are diuretics?
What effect do they have on the production of
urine?
Give examples of substances that have diuretic
effects.
4.02 Understand the functions and disorders of the urinary system
16
17. Fluid and electrolyte balance
Chemical control
Aldosterone
Where does it come from?
What does it do?
Aldosterone release is the result of the renin-
angiotensin system. What does this mean?
4.02 Understand the functions and disorders of the urinary system
17
18. Fluid and electrolyte balance
4.02 Understand the functions and disorders of the urinary system
What effect does this cycle have on your blood pressure?
18
19. Fluid and electrolyte balance
Nervous control
How does the nervous system
control urinary secretions?
What other systems are involved in
the production and excretion of
urine?
4.02 Understand the functions and disorders of the urinary system
19
20. 4.02 Understand the functions and disorders of the urinary system
Review urine formation, electrolyte exchange,
and some factors that effect urine volume.
20
21. What do you predict will happen to blood
pressure when the blood volume increases?
What if blood
volume decreases?
4.02 Understand the functions and disorders of the urinary system
21
22. If more water is reabsorbed back into the
body---what will happen to urine
concentration?
(more or less concentrated?)
4.02 Understand the functions and disorders of the urinary system
22
23. Elimination of urine
What causes the bladder to empty?
Is this a voluntary or involuntary action?
4.02 Understand the functions and disorders of the urinary system
23
24. Elimination of urine
Urinary output
4.02 Understand the functions and disorders of the urinary system
Average urinary output = 1500 ml per day
What effects the
color of your
urine?
24
25. An examination of urine
What does normal urine look like?
What constitutes an abnormal urinalysis?
4.02 Understand the functions and disorders of the urinary system
25
28. Cystitis
What is cystitis
(cyst= medical term for ____ +itis =___ )
Most common cause: E. Coli
What are the major symptoms of cystitis?
4.02 Understand the functions and disorders of the urinary system
28
29. Cystitis
More common in females—Why ??
4.02 Understand the functions and disorders of the urinary system
29
30. Glomerulonephritis
4.02 Understand the functions and disorders of the urinary system
Disease which
injures the
glomerulus.
What will happen
as a result of
damaged
glomeruli?
30
31. Glomerulonephritis
Two types:
• Acute
• Chronic
What is the prognosis for each?
4.02 Understand the functions and disorders of the urinary system
31
32. Renal calculi (Kidney stones)
Also known as nephrolithiasis
nephro lith iasis
What are renal calculi made of?
What are the symptoms?
4.02 Understand the functions and disorders of the urinary system
32
33. Renal calculi
What will happen if
the ureters are
blocked?
4.02 Understand the functions and disorders of the urinary system
33
34. Renal calculi
How is it treated?
4.02 Understand the functions and disorders of the urinary system
34
35. Renal calculi
How does lithotripsy work?
4.02 Understand the functions and disorders of the urinary system
35
36. Renal failure
Acute
• What causes it?
• What are the symptoms?
4.02 Understand the functions and disorders of the urinary system
36
37. Renal failure
chronic
May be none in early stages, urinalysis
may reveal proteinuria
Why would protein be present in the
urine?
Why is this not normal?
4.02 Understand the functions and disorders of the urinary system
37
38. Renal Failure
Chronic kidney
disease leads to a
buildup of fluid and
waste products in
the body.
4.02 Understand the functions and disorders of the urinary system
38
39. Renal Failure
How is it treated?
• Peritoneal dialysis
• What is the process
involved in this
treatment?
4.02 Understand the functions and disorders of the urinary system
39
40. Renal Failure
How is it treated?
• Hemodialysis
• What is
hemodialysis?
4.02 Understand the functions and disorders of the urinary system
40
41. Renal Failure
Compare the treatment of acute and
chronic renal failure.
4.02 Understand the functions and disorders of the urinary system
41
42. How does hemodialysis mimic
glomerular function?
4.02 Understand the functions and disorders of the urinary system
42
43. Renal transplant
What is involved in this treatment option?
When does a patient get a transplant?
4.02 Understand the functions and disorders of the urinary system
43
44. Renal transplant
4.02 Understand the functions and disorders of the urinary system
What is the
major
complication of
renal
transplantation?
44
45. Essential Questions
What are the functions of the urinary system?
What are some disorders of the urinary system?
How are disorders of the urinary system treated?
How do you relate the body’s hormone control to
the urinary system?
4.02 Understand the functions and disorders of the urinary system
45
Notes de l'éditeur
Excretion is the removal of waste from a cell.
The kidney nephrons form urine in three processes: filtration (glomerulus),reabsorption (within renaltubules), and secretion ( by the tubular cells)
Page 430 in text
7500 mL180 liters in 24 hours
Water glucose amino acids vitamins bicarbonate ions and the chloride salts of calcium sodium potassium and magnesium are resbsorbedGo back into the blood stream
This process secretes substances from the blood into the peritubular capillaries into the urine in the distal and collecting tubules
Ammonia creatinine, hydrogen ions, potassium, and some drugs
Electrically charged particles in a solutionMaintain acid base balance
ADH helps to increase the size of the cell membrane pores in the epithelial cells of the distal tubule and collecting ducts by increasing their permeability to water
Increase in osmotic pressure of the blood will trigger ADH to be released. ADH will inhibit normal urine formation and water may be held in the tissues
Diuretics increase urinary output by inhibiting the reabsorption of waterAlcohol and caffeine are examples of diuretics
Secreted from adrenal cortexPromotes the excretion of potassium and hydrogen ions and the reabsorption of sodium ions. Also chloride ions and water are absorbedAs blood passes through the glomerulus to the Bowmans capsule specialized cells can detect a drop in blood pressure. A hormone called Renin is released by the kidneys into the bloodstream. Renin stimulates the release the release of aldosterone from the adrenal cortex and restricts the blood vessels
Increase blood pressure
Completed directly through the action of nerve impulses on the blood vessels leading to the kidney and on those within the kidney leading to the glomerulus.Indirect nerve control is achieved through the stimulation of certain endocrine glands. Hormones will control urinary secretion.
Internal urinary sphincter is involuntary muscle and keeps the urethra closed External urinary sphincter is voluntary muscle.
Page 433 in text
Inflammation of the mucous membrane lining of the urinary bladder. E. coli is normally found in the rectums/s dysuriapolyuria (frequent urination)
Inflammation of the glomerulus of the nephronThe filtration process is affected. Plama proteins are filtered through and protein will be found in the urine and also RBCs will be present (hematuria)
Acute= short termChronic= long lasting and will result in kidney failure
Calcium phosphate and uric acidExtreme pain is usually first signNausea and vomiting BurningFrequent urge to peeChills FeverWeaknessHematuria
Hydronephrosis- fluid gets backed up
Increase in fluid intake to help flush out the stoneMeds to dissolve the stone
Shockwaves help to break down the stones. The stones become sandlike and then can be passed through the urinary system
Occurs suddenly Causes may be from nephritis (inflammation of the nephron), shock, bleeding, sudden heart failure, or poisoningS/S-oliguria or anuria, Uremia can happen due to anuria. s/s of uremia is headaches, dyspnea, nausea, vomitting, and in extreme cases coma and death
A gradual loss of kidney functionProtein should not be able to pass through the capillary membranes of the glomerulus.
This uses the person’s own peritoneal lining instead of a dialyzer to filter the blood. A cleansing solution called dialysate travels through a catheter implanted into the abdomen. Fluids, wastes, electrolytes, and chemicals pass from the tiny blood vessels in the peritoneal membrane into the dialysate. After several hours, the dialysate is drained from the abdomen which takes the wastes from the blood with it. The abdomen is filled with fresh dialysate and the cleaning process begins again. The most common type of peritoneal dialysis is called Continous ambulatory peritoneal dialysis (CAPD). The dialysate solutions stays in the abdomen for 4 to 6 hours. The process of draining the dialysate and replacing it with fresh solution takes about 30 minutes. Most people change the solution four times a day.Automated peritoneal dialysis is performed overnight while the client sleeps. It usually takes 6-8 hours.Complication is peritonitis (inflammation of the peritoneal lining)
Hemodialysis is a process for purifying blood by passing it through thin membranes and exposing it to a solution which continually circulates around the membrane. Substances in the blood pass through the membranes to the lesser concentrated dialysate. The part of the unit that actually substitutes for the kidney is a glass tube called a dialyzer which is filled with thousands of minute hollow fibers attached firmly at both ends. Blood from the client flows through the fibers which are surrounded by circulating dialysate. The dialysate is customized for each patient with appropriate levels of sodium, bicarbonate and other substances. These cross the membrane and enter the blood. At the same time, extra water and waste products leave the blood to enter the dialysate. A fistula which is an opening between an artery and a vein or a graft which is a vein inserted between an artery and a vein is surgically constructed (lasts 3-5 years) This provides a site for the needle to be inserted for dialysis. 2 to 3 x a week and each tx takes 2-4 hours.
Kidney transplant is done in cases of prolonged chronic renal failure involving both kidneys. Usually the person will be on dialysis for a long time awaiting a compatible organ.The kidney can come from a living donor or post mortem donor. Blood and other cellular material must match in order to ensure the greatest potential for a successful transplant
Rejection of the kidney Meds will be taken every day to prevent rejection.