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Platforms for
    Data Science



                               Deepak Singh
       P r i n c i p a l   P r o d u c t   M a n a g e r
bioinformatics
collection
curation
analysis
so what?
Image:Yael Fitzpatrick (AAAS)
lots of data
lots of people
lots of places
constant change
we want to make our
data more effective
versioning
provenance
filter


Via asklar under a CC-BY license
aggregate


Image: Chris Heiler
extend


Image: Bethan
human interfaces


Image: Sebastian Anthony
share
communicate


image: Leo Reynolds
hard problem
really hard problem
so how do
get there?
information
 platforms
Image: Drew Conway
dataspaces


Further reading: Jeff Hammerbacher, Information Platforms and the rise of the data scientist, Beautiful Data
the unreasonable
          effectiveness of data

Halevy, et al. IEEE Intelligent Systems, 24, 8-12 (2009)
accept all data
   formats
evolve APIs
data as a
programmable
   resource
data is a
royal garden
compute is a
fungible commodity
constraints
everywhere
CPU, storage,
   Hardware
                       memory

                  Collections, datasets,
Data management
                       provenance

                     parallelization,
   Software
                      optimization

                  Backup, redundant,
  Availability
                      replicated


     Cost                 Small
remove constraints



Credit: Pieter Musterd a CC-BY-NC-ND license
amazon web services
your
infrastructure
ec2-run-instances
on demand
  global
 secure
programmable
elastic
Netflix needed to transcode
                                   17,000 titles (80TB of data) to
                                   support the launch of Sony PS3.
                                   They provisioned 1200 Amazon
                                   EC2 instances and completed
                                   the transcoding process in just
                                   days.




Source: Adrian Cockroft (Netflix)
Source: Adrian Cockroft (Netflix)
durable
99.999999999%
I did say data was a
    royal garden
performance
“Our 40-instance (m2.2xlarge) cluster can
scan, filter, and aggregate 1 billion rows in
950 milliseconds.”

Mike Driscoll - Metamarkets
WIEN2K Parallel
                                                                    Performance

                                                                          H size 56,000 (25GB)
                                                                     Runtime (16x8 processors)
                                                                        Local (Infiniband) 3h:48
                                                                   Cloud (10Gbps) 1h:30 ($40)




                    1200 atom unit cell; SCALAPACK+MPI
                    diagonalization, matrix size 50k-100k

Credit: K. Jorissen, F. D. Villa, and J. J. Rehr (U. Washington)
“Our tests have shown more than 90
percent scaling efficiency on
clusters of up to 128 GPUs each”
consumption
  models
on-demand
Reserved Instances
what is the value of
   your data?
the clouds
biggest value
remove constraints
Image: Chris Dagdigian
Credit: Angel Pizzaro, U. Penn
13k sequences
 - 10 min
 - 0.1s per sequence
mapreduce for
  genomics
 http://bowtie-bio.sourceforge.net/crossbow/index.shtml
            http://contrail-bio.sourceforge.net
   http://bowtie-bio.sourceforge.net/myrna/index.shtml
30,472 cores
$1279/hr
http://cloudbiolinux.org/
http://usegalaxy.org/cloud
“The process of moving StarMolsim over to the cloud to support the “Introduction to
Modeling and Simulation” course at MIT was a huge success. The cloud enabled the STAR
group to move away from the responsibility of owning and maintaing dedicated hardware
and instead focus on their core mission of developing software and services for faculty,
students, and researchers at MIT”




                       http://web.mit.edu/stardev/cluster/about.html
in summary
large scale data
requires a rethink
data architecture
compute architecture
distributed,
programmable
 infrastructure
amazon web services
remove constraints
can we build data
science platforms?
there is no magic
there is only awesome
deesingh@amazon.com
                                                             Twitter:@mndoci
                                               http://slideshare.net/mndoci
                                                          http://mndoci.com




         Inspiration and ideas from
          Matt Wood& Larry Lessig


Credit” Oberazzi under a CC-BY-NC-SA license

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