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23/02/2012



                   HAPPY SEXY
                   HORMONES
                   BY

MORWENNA GIVEN
BA MA (OXON) BSC M.OHA BHG RH
MEDICAL HERBALIST
WW.MEDICUSHERBIS.COM
                                1
               ©
2         23/02/2012




         Who am I?


oI am a Medical Herbalist
 practising in downtown Toronto
 treating a variety of disease
 and specialising in cancer and
 pre cancerous conditions. Most
 of which start with hormone
 imbalances
              ©
3                   23/02/2012




         HOW AM I TRAINED?
   I did 6 years of training in University, Hospital
    and Clinic settings

   Training in the Western bio-chemical physician
    model ( like an MD )

   Additional training in pharmacology,
    biochemistry, phytochemistry, to treat
    medical conditions with plant medicine and
    to work with conventional drugs/MD’s

                         ©
4                 23/02/2012




        WHAT IS A MEDICAL
           HERBALIST?
 We  use a wholistic approach to disease
 A specialist in the use of medicinal plants
  to resolve disease
 Practice is based on internationally
  accepted scientific evidence
 We can treat in combination with
  orthodox drugs
 We treat individually & compound

                     ©
5                  23/02/2012




          EVIDENCE BASE
 MD’s    and Medical Herbalists apply their
  skills using the same internationally
  accepted evidence base
 Composed of peer reviewed journals,
  trials, studies, observation, in vivo and in
  vitro evidence most of which can be
  found on the database known as
  Pubmed.
                     ©
6                                23/02/2012




             My      patient contract contains the words:

       “I may recommend walks, movies, laughter as well as
        specific herbs and nutritional therapies. “


 This is apparently now acceptable - It is evidence
    based!!!

   “ Laughter & therapy could go a long way for the heart” European Society of Cardiology 20ll study on
    endothelial function & laughter
                                              ©
7               23/02/2012




          HOMEOSTASIS
 Thisis the term for the body to be in
  perfect equilibrium to undertake its
  functions.
 UNHAPPY Hormones indicate the body is
  not in equilibrium – whatever the cause

A  herbalist always approaches resolving
  disease by considering homeostasis
                  ©
8                 23/02/2012




     WHAT IS A HORMONE
A  substance produced in the body from a
  gland
 Thyroid e.g. TSH


 They   are broadly divided into 2 groups –
  fat or water soluble
 And carried to other parts of the body to
  elicit a response from a tissue, structure or
  chemical receptor e.g. T4
9           23/02/2012




WHERE DO WE FIND THEM ?
 Hormones  are found in :
 Brain & HPA & Pineal glands
 Thyroid/parathyroid/kidney
 Adrenal glands/pancreas/liver
 Ovaries/breast/uterus
 Prostate/breast
 Fat


                                          ©
10               23/02/2012




       EACH LOCATION
        HAS AN ACTION
 Pineal gland stores and releases
  melatonin
 The Adrenal gland syntheses and releases
  cortisol, oestrogen
 The parathyroid gland stores and releases
  calcitonin


                                                ©
11                   23/02/2012




                    THYROID
   This is one of the most important glands
   In Ontario subclinical hypothyroidism is endemic
   Affects all metabolic functions
   Affects the liver, immunity, sex hormones, energy
    hormones, bone health
   Principal hormones are TSH, free T3 free T4
   Thyroid peroxidase
    No conventional treatment for subclinical disorder
   But I have lots of plants for this problem

                                                           ©
12                 23/02/2012




                    LIVER
 The    most important organ of the body

 It   makes cholesterol and other hormones

 Itclears and breaks down for removal
  steroid hormones. (sexual and energy)
 Liver health is the key to happy hormones


                                                    ©
13               23/02/2012




            7 AGES OF MAN
 Hormones change as we change
 Men every 24hrs in women every 28 days


 If   music be the food of love play on

 12th    Night & Apologies to Shakespeare!

 And     change again as we age
                     ©
14                   23/02/2012




     Which ones change?
 Hormones   that do not tend to change
 significantly with age are:

 TSH,   Cortisol, Insulin, Oestrogen in men,

 Unless
       there is a lifestyle or disease
 problem


                                                        ©
15              23/02/2012




   Hormones that change
 With age are:
 ACTH, FSH, SHBG, DHEA
 - the sexy hormones


 Adrenaline/noradrenaline, parathyroid,
  ANP, digestive hormones, melatonin
 - The energy hormones


                                               ©
16              23/02/2012




        FEED BACK LOOP
 Hormones    operate in a feedback loop
  mechanism
 Problems occur when this feed back loop
  is altered/inhibited in any way.
 And creates disease
 Known as the endocrine axes =
  endocrinology


                                              ©
17                   23/02/2012


FEMALE CYCLE

Feed back loop
                                HPA

           hcg

                                      THYROID
         PROGE
         STERON
            E

                                      OESTRO
                                       GEN
                  FSH/LH


                                                        ©
18                23/02/2012




    WORK IN PARTNERSHIP
  hormones do not work in isolation
 They respond to other physiological
  signals
 The whole body is a jigsaw of
  interconnectedness and when one
  aspect is out sync then it causes dis-ease
 Adequate levels of zinc, selenium,
  chromium

                                                  ©
19                  23/02/2012




       CONSEQUENCES OF
       UNHAPPY HORMONES
 Cancer     – chronic endocrine disease
 Diabetes – insulin resistance
 Cushings - stress
 Hashimoto’s , Graves (thyroid)
 Infertility, women’s problems PMS etc.,
  PCOS
 Osteoporosis,
 Insomnia
                                                    ©
20               23/02/2012




              CANCER
 The most common cancers, breast,
  prostate are hormone driven
 The next most common cancers
  colon/lung and driven secondarily by
  hormones
 The approach of cut, burn, poison cannot
  control hormones and does not address
  the cause of the cancer.
 Plants can!!

                                               ©
21                23/02/2012




    MALE VS FEMALE HORMONES


 OESTROGEN (3) PROGESTERONE
Fsh, Lh, prolactin, oxytocin, androgens

o   TESTOSTERONE, OESTROGEN, Lh, Fsh,
    androgens

                                                  ©
22                 23/02/2012




 LIBIDO PCOS MENOPAUSE
 Problems
         with these conditions can be
 caused by hormones

 Libido– lack of LH, oestrogen
 PCOS – imbalance Fsh/LH, insulin
 Menopause – imbalance
  oestrogen/progesterone
 ALL AFFECTED BY THYROID HORMONES
23               23/02/2012




        BPH MALE INFERTILITY
           ANDROPAUSE

 Benign    Prostatic hyperplasia – DHT,
  testosterone, oestrogen
 Infertility – LH, testosterone
 Andropause – all male hormones


 ALL   AFFECTED BY THYROID HORMONES
24              23/02/2012




                  PLANTS

    A huge variety of plants have
    applications for hormonal control – some
    are Black cohorsh, Chaste berry, Dong
    Quai, Red Clover, St John’s wort, Saw
    palmetto, nettle each addressing various
    aspects of the hormonal cycle with
    different parts of the plant having a
    specific effect
                                                 ©
25   23/02/2012
26   23/02/2012




                               Hormonal plants
   VITEX – Agnus Castus
   A member of the verbenaceae genus traditionally
    used for menopause, fertility, dysmenorrhea, BPH,
    cancer, hyperprolactaemia, PCOS, acne etc.
   It has the capacity to balance hormones at the
    HPA, and is antimicrobial
   inhibits arachinadonic acid metabolism helps to
    block tumour growth cox/lox pathways
   anti emetic effect thru blocking 5HTT receptors
   releases substance P potential use in anti
    anxiolytic and anti inflammatory mechanisms



    2009 Chen. Chinese double blind trial shows effectiveness in PMS use
    2009 Mesaick. Casticin a potent anti inflammatory and immodulatory flavonoid
                                                                                                ©
   BMJ. 2001 January 20; 322(7279): 134–137. PMCID: PMC26589
   Treatment for the premenstrual syndrome
27                                   23/02/2012


                      Synergy
   Plants have survived by
    adapting to hostile
    environments which has
    resulted in the production
    of secondary metabolites
    which we use in plant
    medicine.
   Plants when used
    together have a greater
    result than the sum of
    their parts.
   Unlike conventional
    medicine which is reliant
    on a single
    action/pathway               Fitoterapia. 2011 Apr;82(3):474-80. Pharmacological
                                 studies in an herbal drug combination of St. John's
    although now some            Wort (Hypericum perforatum)
    recognition of multi drug    and Passion Flower (Passiflora incarnata): in vitro and
                                  in vivo evidence of synergy between Hypericum and
    therapies. ©                 Passiflora . Fiebich BL et al . University of Freiburg Medical
                                 School,
28                  23/02/2012




      STEROID HORMONES
 HORMONES:   ARE STEROID COMPOUNDS
 DERIVED INITIALLY FROM CHOLESTEROL.

 Progestins,   corticosteroids, oestrogens,
 androgens

 DRUGS SUCH AS STATINS & HRT interfere
 with hormones and vitamin absorption
                                                       ©
29                 23/02/2012




       CHOLESTROL/STATINS
 An artificially low level of cholesterol in the
  body can cause significant problems -
including diabetes; auto immune
conditions, raised pain levels

Happy hormones are hormones produced
in balanced quantities for their function in
the body

                                                     ©
30                     23/02/2012




         Hormonal resolution
   The only solution that has successfully been
    shown to support hormonal changes without
    further issues is plants

   Synthetic hormones are not plants
   Dietary restriction. ( Fat is totally relevant)

   Drugs produce severe side effects in many
    cases leading to further disease
   E.g. HRT, Avandia, statins, bisphosphonates

                                                              ©
31               23/02/2012




          Hormonal plants
 Red   Clover

A lovely sweet tasting plant which can be
 used for both upper respiratory conditions
 and women’s problems. Traditionally used
 for skin complaints. Its phytoestrogens
 have agonist and antagonist properties &
 lymphatic actions

                                                ©
32                23/02/2012




                CAUTIONS
   The compounds that I give do not come from
    over the counter products
   Only registered herbalists may compound
    and use these products which are made
    under the same regulations as drugs

   If you self treat, you may cause further
    problems
   Please do not confuse these plants/medicine
    with supplements which by law cannot have
    medically therapeutic effects.

                                                    ©
33               23/02/2012




                REFERENCES
   For a complete copy of all references used in
    this presentation (@15 pages), please email:
    mrsmg@sympatico.ca

   Please note that many peer reviewed articles
    are based on supplements not whole plant
    extracts e.g. Canmat 2009

   All reference material is available on
    Pubmed/Science Direct
                                                      ©
34              23/02/2012




    THANKYOU




      Morwenna Given
Registered Medical Herbalist
 www.medicusherbis.com                 ©

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Happy sexy hormones

  • 1. 23/02/2012 HAPPY SEXY HORMONES BY MORWENNA GIVEN BA MA (OXON) BSC M.OHA BHG RH MEDICAL HERBALIST WW.MEDICUSHERBIS.COM 1 ©
  • 2. 2 23/02/2012 Who am I? oI am a Medical Herbalist practising in downtown Toronto treating a variety of disease and specialising in cancer and pre cancerous conditions. Most of which start with hormone imbalances ©
  • 3. 3 23/02/2012 HOW AM I TRAINED?  I did 6 years of training in University, Hospital and Clinic settings  Training in the Western bio-chemical physician model ( like an MD )  Additional training in pharmacology, biochemistry, phytochemistry, to treat medical conditions with plant medicine and to work with conventional drugs/MD’s ©
  • 4. 4 23/02/2012 WHAT IS A MEDICAL HERBALIST?  We use a wholistic approach to disease  A specialist in the use of medicinal plants to resolve disease  Practice is based on internationally accepted scientific evidence  We can treat in combination with orthodox drugs  We treat individually & compound ©
  • 5. 5 23/02/2012 EVIDENCE BASE  MD’s and Medical Herbalists apply their skills using the same internationally accepted evidence base  Composed of peer reviewed journals, trials, studies, observation, in vivo and in vitro evidence most of which can be found on the database known as Pubmed. ©
  • 6. 6 23/02/2012  My patient contract contains the words:  “I may recommend walks, movies, laughter as well as specific herbs and nutritional therapies. “  This is apparently now acceptable - It is evidence based!!!  “ Laughter & therapy could go a long way for the heart” European Society of Cardiology 20ll study on endothelial function & laughter  ©
  • 7. 7 23/02/2012 HOMEOSTASIS  Thisis the term for the body to be in perfect equilibrium to undertake its functions.  UNHAPPY Hormones indicate the body is not in equilibrium – whatever the cause A herbalist always approaches resolving disease by considering homeostasis ©
  • 8. 8 23/02/2012 WHAT IS A HORMONE A substance produced in the body from a gland  Thyroid e.g. TSH  They are broadly divided into 2 groups – fat or water soluble  And carried to other parts of the body to elicit a response from a tissue, structure or chemical receptor e.g. T4
  • 9. 9 23/02/2012 WHERE DO WE FIND THEM ?  Hormones are found in :  Brain & HPA & Pineal glands  Thyroid/parathyroid/kidney  Adrenal glands/pancreas/liver  Ovaries/breast/uterus  Prostate/breast  Fat ©
  • 10. 10 23/02/2012 EACH LOCATION HAS AN ACTION  Pineal gland stores and releases melatonin  The Adrenal gland syntheses and releases cortisol, oestrogen  The parathyroid gland stores and releases calcitonin ©
  • 11. 11 23/02/2012 THYROID  This is one of the most important glands  In Ontario subclinical hypothyroidism is endemic  Affects all metabolic functions  Affects the liver, immunity, sex hormones, energy hormones, bone health  Principal hormones are TSH, free T3 free T4  Thyroid peroxidase  No conventional treatment for subclinical disorder  But I have lots of plants for this problem ©
  • 12. 12 23/02/2012 LIVER  The most important organ of the body  It makes cholesterol and other hormones  Itclears and breaks down for removal steroid hormones. (sexual and energy)  Liver health is the key to happy hormones ©
  • 13. 13 23/02/2012 7 AGES OF MAN  Hormones change as we change  Men every 24hrs in women every 28 days  If music be the food of love play on  12th Night & Apologies to Shakespeare!  And change again as we age ©
  • 14. 14 23/02/2012 Which ones change?  Hormones that do not tend to change significantly with age are:  TSH, Cortisol, Insulin, Oestrogen in men,  Unless there is a lifestyle or disease problem ©
  • 15. 15 23/02/2012 Hormones that change  With age are:  ACTH, FSH, SHBG, DHEA  - the sexy hormones  Adrenaline/noradrenaline, parathyroid, ANP, digestive hormones, melatonin  - The energy hormones ©
  • 16. 16 23/02/2012 FEED BACK LOOP  Hormones operate in a feedback loop mechanism  Problems occur when this feed back loop is altered/inhibited in any way.  And creates disease  Known as the endocrine axes = endocrinology ©
  • 17. 17 23/02/2012 FEMALE CYCLE Feed back loop HPA hcg THYROID PROGE STERON E OESTRO GEN FSH/LH ©
  • 18. 18 23/02/2012 WORK IN PARTNERSHIP  hormones do not work in isolation  They respond to other physiological signals  The whole body is a jigsaw of interconnectedness and when one aspect is out sync then it causes dis-ease  Adequate levels of zinc, selenium, chromium ©
  • 19. 19 23/02/2012 CONSEQUENCES OF UNHAPPY HORMONES  Cancer – chronic endocrine disease  Diabetes – insulin resistance  Cushings - stress  Hashimoto’s , Graves (thyroid)  Infertility, women’s problems PMS etc., PCOS  Osteoporosis,  Insomnia ©
  • 20. 20 23/02/2012 CANCER  The most common cancers, breast, prostate are hormone driven  The next most common cancers colon/lung and driven secondarily by hormones  The approach of cut, burn, poison cannot control hormones and does not address the cause of the cancer.  Plants can!! ©
  • 21. 21 23/02/2012 MALE VS FEMALE HORMONES  OESTROGEN (3) PROGESTERONE Fsh, Lh, prolactin, oxytocin, androgens o TESTOSTERONE, OESTROGEN, Lh, Fsh, androgens ©
  • 22. 22 23/02/2012 LIBIDO PCOS MENOPAUSE  Problems with these conditions can be caused by hormones  Libido– lack of LH, oestrogen  PCOS – imbalance Fsh/LH, insulin  Menopause – imbalance oestrogen/progesterone  ALL AFFECTED BY THYROID HORMONES
  • 23. 23 23/02/2012 BPH MALE INFERTILITY ANDROPAUSE  Benign Prostatic hyperplasia – DHT, testosterone, oestrogen  Infertility – LH, testosterone  Andropause – all male hormones  ALL AFFECTED BY THYROID HORMONES
  • 24. 24 23/02/2012 PLANTS  A huge variety of plants have applications for hormonal control – some are Black cohorsh, Chaste berry, Dong Quai, Red Clover, St John’s wort, Saw palmetto, nettle each addressing various aspects of the hormonal cycle with different parts of the plant having a specific effect ©
  • 25. 25 23/02/2012
  • 26. 26 23/02/2012 Hormonal plants  VITEX – Agnus Castus  A member of the verbenaceae genus traditionally used for menopause, fertility, dysmenorrhea, BPH, cancer, hyperprolactaemia, PCOS, acne etc.  It has the capacity to balance hormones at the HPA, and is antimicrobial  inhibits arachinadonic acid metabolism helps to block tumour growth cox/lox pathways  anti emetic effect thru blocking 5HTT receptors  releases substance P potential use in anti anxiolytic and anti inflammatory mechanisms   2009 Chen. Chinese double blind trial shows effectiveness in PMS use 2009 Mesaick. Casticin a potent anti inflammatory and immodulatory flavonoid ©  BMJ. 2001 January 20; 322(7279): 134–137. PMCID: PMC26589  Treatment for the premenstrual syndrome
  • 27. 27 23/02/2012 Synergy  Plants have survived by adapting to hostile environments which has resulted in the production of secondary metabolites which we use in plant medicine.  Plants when used together have a greater result than the sum of their parts.  Unlike conventional medicine which is reliant on a single action/pathway Fitoterapia. 2011 Apr;82(3):474-80. Pharmacological studies in an herbal drug combination of St. John's although now some Wort (Hypericum perforatum) recognition of multi drug and Passion Flower (Passiflora incarnata): in vitro and in vivo evidence of synergy between Hypericum and therapies. © Passiflora . Fiebich BL et al . University of Freiburg Medical School,
  • 28. 28 23/02/2012 STEROID HORMONES  HORMONES: ARE STEROID COMPOUNDS DERIVED INITIALLY FROM CHOLESTEROL.  Progestins, corticosteroids, oestrogens, androgens  DRUGS SUCH AS STATINS & HRT interfere with hormones and vitamin absorption ©
  • 29. 29 23/02/2012 CHOLESTROL/STATINS  An artificially low level of cholesterol in the body can cause significant problems - including diabetes; auto immune conditions, raised pain levels Happy hormones are hormones produced in balanced quantities for their function in the body ©
  • 30. 30 23/02/2012 Hormonal resolution  The only solution that has successfully been shown to support hormonal changes without further issues is plants  Synthetic hormones are not plants  Dietary restriction. ( Fat is totally relevant)  Drugs produce severe side effects in many cases leading to further disease  E.g. HRT, Avandia, statins, bisphosphonates ©
  • 31. 31 23/02/2012 Hormonal plants  Red Clover A lovely sweet tasting plant which can be used for both upper respiratory conditions and women’s problems. Traditionally used for skin complaints. Its phytoestrogens have agonist and antagonist properties & lymphatic actions ©
  • 32. 32 23/02/2012 CAUTIONS  The compounds that I give do not come from over the counter products  Only registered herbalists may compound and use these products which are made under the same regulations as drugs  If you self treat, you may cause further problems  Please do not confuse these plants/medicine with supplements which by law cannot have medically therapeutic effects. ©
  • 33. 33 23/02/2012 REFERENCES  For a complete copy of all references used in this presentation (@15 pages), please email: mrsmg@sympatico.ca  Please note that many peer reviewed articles are based on supplements not whole plant extracts e.g. Canmat 2009  All reference material is available on Pubmed/Science Direct ©
  • 34. 34 23/02/2012 THANKYOU Morwenna Given Registered Medical Herbalist www.medicusherbis.com ©