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Welcome to the Session of
Unipril
(Ramipril BP 2.5 & 5)
Presented by
Mohammed Moshiur Rahaman
Brand Executive
Brand Management Department
The ACME Laboratories Ltd.
Product Information
 Brand Name : Unipril 2.5 & 5
 Composition : Ramipril BP 2.5 & 5
 Therapeutic group : Antihypertensive (ACE inhibitor)
 Product group :
 Pack Size : 3 X10’s
 Unit Price : 5.01 tk/unit (2.5 mg) tablet
8.04 tk/unit (5 mg) tablet
Mechanism of Action
Unipril inhibits conversion of Angiotensin I to
Angiotensin II by inhibiting Angiotensin converting
Enzyme (ACE).
Angiotensinogen (from the liver)
Renin from Kidney
Angiotensin I
ACE enzyme
No production of Angiotensin II
Blood pressure decreases
Unipril inhibits
ACE enzyme
Unipril (Ramipril) ppt
Market Information:
The market size of Ramipril is 22 crore (appr.) with Growth 15.9%.
Brand Company Sales value(crore)
yearly
Ramoril Incepta 7.92
Ramace Opsonin 3.32
Tritace Sanofi Aventis 2.91
Ripril Square 1.50
Piramil Sandoz 1.41
Indications
 Mild to severe hypertension, where it may be used alone
or in combination with thiazide diuretics.
 Congestive heart failure
 To reduce the risk of stroke, myocardial infarction and
death from cardiovascular events in patients with a
history of cardiovascular diseases
 Proteinuric non-diabetic nephropathy
Unipril reduces CV events in high risk patients
According to HOPE study, Ramipril significantly reduces the rate of death, myocardial
infarction and stroke in a broad range of high risk patients who are not known to have a
low ejection fraction or heart failure.
…..An appropriate choice for CV
patients
Unipril shows the highest survival rate among all ACE
inhibitors
After the incidence of acute MI, patients were treated with different ACE
inhibitors. Ramipril shows significant lower mortality than other ACE
inhibitors.
……Better for MI patients
Unipril offers beneficial effects in people with diabetic
patients
According to MICRO-HOPE study, Ramipril significantly reduces the
cardiovascular death, stroke and heart attack in patients with diabetes.
……A perfect choice for diabetic
patients
Unipril provides effective improvement of all
parameters in Chronic Nephropathy
 
According to REIN study, in patient with chronic nephropathy & high risk of
rapid progression of ESRD, Ramipril reversed the tendency of GFR to decline
with time. Moreover, a treatment period of sufficient duration (≥36 months )
eliminated the need for dialysis.
……shows effective and consistent renoprotective effect
Use In Pregnancy And Lactation
Pregnancy
Pregnancy should be excluded before start of treatment with
Ramipril and avoided during treatment. However, if
pregnancy is detected, Unipril (Ramipril) should be
discontinued as early as possible unless continued use is
considered life saving.
Lactation
Ramipril should not be used during lactation.
Target Doctors
 Cardiologist
 Neurologist
 Medicine specialist
 General practitioners
 Hospital practitioners
Highlighting Points
Unipril…
 is an appropriate choice for CV patients
 prevents premature death in acute MI
 reduces the atherosclerosis progression
 offers beneficial effects in diabetic patients
 ensures effective renal protection
 shows better tolerability
Unipril (Ramipril) ppt
Thank you all

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Unipril (Ramipril) ppt

  • 1. Welcome to the Session of Unipril (Ramipril BP 2.5 & 5) Presented by Mohammed Moshiur Rahaman Brand Executive Brand Management Department The ACME Laboratories Ltd.
  • 2. Product Information  Brand Name : Unipril 2.5 & 5  Composition : Ramipril BP 2.5 & 5  Therapeutic group : Antihypertensive (ACE inhibitor)  Product group :  Pack Size : 3 X10’s  Unit Price : 5.01 tk/unit (2.5 mg) tablet 8.04 tk/unit (5 mg) tablet
  • 3. Mechanism of Action Unipril inhibits conversion of Angiotensin I to Angiotensin II by inhibiting Angiotensin converting Enzyme (ACE).
  • 4. Angiotensinogen (from the liver) Renin from Kidney Angiotensin I ACE enzyme No production of Angiotensin II Blood pressure decreases Unipril inhibits ACE enzyme
  • 6. Market Information: The market size of Ramipril is 22 crore (appr.) with Growth 15.9%. Brand Company Sales value(crore) yearly Ramoril Incepta 7.92 Ramace Opsonin 3.32 Tritace Sanofi Aventis 2.91 Ripril Square 1.50 Piramil Sandoz 1.41
  • 7. Indications  Mild to severe hypertension, where it may be used alone or in combination with thiazide diuretics.  Congestive heart failure  To reduce the risk of stroke, myocardial infarction and death from cardiovascular events in patients with a history of cardiovascular diseases  Proteinuric non-diabetic nephropathy
  • 8. Unipril reduces CV events in high risk patients According to HOPE study, Ramipril significantly reduces the rate of death, myocardial infarction and stroke in a broad range of high risk patients who are not known to have a low ejection fraction or heart failure. …..An appropriate choice for CV patients
  • 9. Unipril shows the highest survival rate among all ACE inhibitors After the incidence of acute MI, patients were treated with different ACE inhibitors. Ramipril shows significant lower mortality than other ACE inhibitors. ……Better for MI patients
  • 10. Unipril offers beneficial effects in people with diabetic patients According to MICRO-HOPE study, Ramipril significantly reduces the cardiovascular death, stroke and heart attack in patients with diabetes. ……A perfect choice for diabetic patients
  • 11. Unipril provides effective improvement of all parameters in Chronic Nephropathy   According to REIN study, in patient with chronic nephropathy & high risk of rapid progression of ESRD, Ramipril reversed the tendency of GFR to decline with time. Moreover, a treatment period of sufficient duration (≥36 months ) eliminated the need for dialysis. ……shows effective and consistent renoprotective effect
  • 12. Use In Pregnancy And Lactation Pregnancy Pregnancy should be excluded before start of treatment with Ramipril and avoided during treatment. However, if pregnancy is detected, Unipril (Ramipril) should be discontinued as early as possible unless continued use is considered life saving. Lactation Ramipril should not be used during lactation.
  • 13. Target Doctors  Cardiologist  Neurologist  Medicine specialist  General practitioners  Hospital practitioners
  • 14. Highlighting Points Unipril…  is an appropriate choice for CV patients  prevents premature death in acute MI  reduces the atherosclerosis progression  offers beneficial effects in diabetic patients  ensures effective renal protection  shows better tolerability