08 hiv and aids[1]

HIV and AIDS HIV: Human Immunodeficiency Virus

HIV and AIDS AIDS: Acquired Immune Deficiency Syndrome OR Acquired Immunodeficiency Syndrome

HIV and AIDS: MYTHS ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],TRUE FALSE

[object Object],[object Object],[object Object],HIV and AIDS

HIV and AIDS Peripheral Fat Wasting (lipodystrophy)

Central Dogma DNA  RNA  Protein ,[object Object],[object Object],[object Object],[object Object],[object Object],HIV and AIDS

Transcription HIV and AIDS Copying DNA into RNA Reverse Transcription? Copying RNA into DNA

HIV: A retrovirus Receptors: CD4 molecules Coreceptors: fusin, CCR5 HIV and AIDS

Retroviruses (RNA Virus) Retroviruses have an enzyme (called reverse transcriptase) that is capable of reverse transcribing their RNA into DNA . This viral DNA can then be integrated into the host cell’s genome. HIV and AIDS

[object Object],[object Object],[object Object],[object Object],Retroviruses (RNA Virus) HIV and AIDS

[object Object],Retroviruses (RNA Virus) HIV and AIDS

[object Object],Retroviruses (RNA Virus) HIV and AIDS http://www.youtube.com/watch?v=dn1tNIrMPRk&feature=related

Retroviruses (RNA Virus) Retroviruses replicate with a high mutation rate, because reverse transcriptase makes several errors! This increases it’s ability to evolve and survive. HIV and AIDS Some mutations will change the virus’ “appearance” and make it unrecognizable to the immune system

T-Cells ,[object Object],[object Object],[object Object],[object Object],HIV and AIDS

Pathology of HIV ,[object Object],[object Object],[object Object],Campbell Fig. 43.19 HIV and AIDS

HIV targets helper T-Cells ,[object Object],HIV and AIDS

HIV targets helper T-Cells HIV and AIDS

HIV and AIDS Helper T-cells are essential to the immune system HIV infects helper T-cells Therefore HIV stops the immune system from working

Helper T-cells are essential to the immune system HIV and AIDS HIV Destroy foreign cells Kill infected cells

HIV treatment http://www.youtube.com/watch?v=mzfnxCEsck4 HIV and AIDS

http://www.youtube.com/watch?v=eS1GODinO8w

How HIV is spread ,[object Object],[object Object],[object Object],[object Object],HIV and AIDS

How HIV is spread HIV and AIDS

How vaccines work http://www.youtube.com/watch?v=C061bmvk7Hw HIV and AIDS

Challenges with AIDS vaccines ,[object Object],[object Object],[object Object],HIV and AIDS

Retroviruses (RNA Virus) HIV and AIDS

08 hiv and aids[1]

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08 hiv and aids[1]

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