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What Is Cholesterol?
• We may associate cholesterol
with fatty foods, but most of the
waxy substance is made by
our own bodies. The liver
produces 75% of the
cholesterol that circulates in
our blood. The other 25%
comes from food. At normal
levels, cholesterol actually
plays an important role in
helping cells do their jobs. But
cholesterol levels are
precariously high in more than
100 million Indians.
Symptoms of High Cholesterol
• High cholesterol does not
cause any symptoms. But it
does cause damage deep
within the body. Over time, too
much cholesterol may lead to
a buildup of plaque inside the
arteries. Known as
atherosclerosis, this condition
narrows the space available
for blood flow and can trigger
heart disease. The good news
is high cholesterol is simple to
detect, and there are many
ways to bring it down.
Cholesterol Testing
• People older than 20 should
have their cholesterol levels
checked at least once every
five years. This is done with a
simple blood test known as a
fasting lipoprotein profile. It
measures the different forms
of cholesterol that are
circulating in your blood after
you avoid eating for 9 to 12
hours. The results show your
levels of "bad" cholesterol,
"good" cholesterol, and
triglycerides.
"Bad" Cholesterol
• Most of the cholesterol in the
blood is carried by proteins
called low density lipoproteins
or LDL. This is known as the
bad cholesterol because it
combines with other
substances to clog the
arteries. A diet high in
saturated fats and trans fats
tends to raise the level of LDL
cholesterol. For most people,
an LDL score below 100 is
healthy, but people with heart
disease may need to aim even
lower.
"Good" Cholesterol
• Up to a third of blood
cholesterol is carried by high-
density lipoproteins or HDL.
This is called good cholesterol
because it helps remove bad
cholesterol, preventing it from
building up inside the arteries.
The higher the level of HDL
cholesterol, the better. People
with too little are more likely to
develop heart disease. Eating
healthy fats, such as olive oil,
may help boost HDL
cholesterol.
Triglycerides
• The body converts excess
calories, sugar, and alcohol
into triglycerides, a type of fat
that is carried in the blood and
stored in fat cells throughout
the body. People who are
overweight, inactive, smokers,
or heavy drinkers tend to have
high triglycerides, as do those
who eat a very high-carb diet.
A triglycerides score of 150 or
higher puts you at risk for
metabolic syndrome, which is
linked to heart disease and
diabetes.
Total Cholesterol
• Total cholesterol measures the
combination of LDL, HDL, and
VLDL (very low density
lipoprotein) in your
bloodstream. VLDL is a
precursor of LDL, the bad
cholesterol. A total cholesterol
score of under 200 is
considered healthy in most
cases. People who score in
the "high" range have an
increased risk of developing
heart disease compared to
those who score below 200.
Cholesterol Ratio
• To calculate your cholesterol
ratio, divide your total
cholesterol by your HDL
cholesterol. For example, a
total score of 200 divided by
an HDL score of 50 equals a
cholesterol ratio of 4 to 1.
Doctors recommend
maintaining a ratio of 4 to 1 or
lower. The smaller the ratio,
the better. While this figure is
useful in estimating heart
disease risk, it's not as
important in guiding treatment.
Doctors look at total
cholesterol, HDL cholesterol,
and LDL cholesterol to
determine treatment.
Cholesterol in Food
• Cholesterol-rich foods, like
eggs, shrimp, and lobster are
no longer completely
forbidden. Research shows
that the cholesterol we eat has
only a small effect on blood
cholesterol levels for most
people. A few people are
"responders," whose blood
levels spike up after eating
eggs. But for most, saturated
fat and trans fats are bigger
concerns. Daily cholesterol
limits are 300 mg for healthy
people and 200 mg for those
at higher risk. One egg has
186 mg of cholesterol.
Cholesterol and Family History
• Cholesterol comes from two
sources -- the body and food --
and either one can contribute
to high cholesterol. Some
people inherit genes that
trigger too much cholesterol
production. For others, diet is
the main culprit. Saturated fat
and cholesterol occur in
animal-based foods, including
meat, eggs, and dairy products
made with milk. In many
cases, high cholesterol stems
from a combination of diet and
genetics.
What Boosts Your Risk?
Several factors can make
you more likely to
develop high cholesterol:
• A diet high in saturated
fats and cholesterol
• A family history of high
cholesterol
• Being overweight or
obese
• Getting older
Cholesterol and Gender
• Until menopause, women
typically have lower total
cholesterol levels than men of
the same age. They also have
higher levels of HDL
cholesterol, the good kind.
One reason is estrogen: The
female sex hormone raises the
level of HDL cholesterol.
Estrogen production peaks
during the childbearing years
and drops off during
menopause. After age 55, a
woman's risk of developing
high cholesterol begins to
climb.
Cholesterol and Children
• There's evidence that
cholesterol can begin
clogging the arteries
during childhood, leading
to atherosclerosis and
heart disease later in life.
The American Heart
Association recommends
kids and teenagers with
high cholesterol take
steps to bring it down.
Ideally, total cholesterol
should be below 170 in
people ages 2 to 19.
Why High Cholesterol Matters
• High cholesterol is one of the
major risk factors for coronary
artery disease, heart attacks,
and strokes. It also appears to
boost the risk of Alzheimer's
disease. As we saw earlier,
high cholesterol leads to a
buildup of plaque that narrows
the arteries. This is dangerous
because it can restrict blood
flow. If the blood supply to a
part of the heart or brain is
completely cut off, the result is
a heart attack or stroke.
Cholesterol Buster: Eat More Fiber
• Diet changes offer a
powerful way to fight high
cholesterol. If you've ever
wondered why some
cereals claim to be heart-
healthy, it's the fiber. The
soluble fiber found in
many foods helps reduce
LDL, the bad cholesterol.
Good sources of soluble
fiber include whole-grain
breads and cereals,
oatmeal, fruits, dried
fruits, vegetables, and
legumes such as kidney
beans.
Cholesterol Buster: Know Your
Fats
• No more than 35% of your daily
calories should come from fat.
But not all fats are equal.
Saturated fats -- from animal
products and tropical oils --
raise LDL cholesterol. Trans
fats carry a double-whammy,
boosting bad cholesterol,
while lowering the good kind.
These two bad fats are found
in many baked goods, fried
foods (doughnuts, french fries,
chips), stick margarine, and
cookies. Unsaturated fats may
lower LDL when combined
with other healthy diet
changes. They're found in
avocados, olive oil, and peanut
oil.
Cholesterol Buster: Smart Protein
• Meat and full-fat milk offer
plenty of protein, but they are
also major sources of
cholesterol. You may be able
to reduce LDL cholesterol by
switching to soy protein, such
as tofu, at some meals. Fish is
another great choice. It's rich
in omega-3 fatty acids, which
can improve cholesterol levels.
The American Heart
Association recommends
eating fish at least twice a
week.
Cholesterol Buster: Low-Carb Diet
• There's growing evidence
that low-carb diets may
be better than low-fat
diets for improving
cholesterol levels. In a
two-year study funded by
the National Institutes of
Health, people who
followed a low-carb plan
had significantly better
HDL (good cholesterol)
levels than those who
followed a low-fat plan.
Cholesterol Buster: Lose Weight
• If you're overweight, talk
to your doctor about
beginning a weight loss
program. Losing weight
can help you reduce your
levels of triglycerides,
LDL, and total
cholesterol. Shedding
even a few pounds can
also boost your good
cholesterol level -- it
tends to go up 1 point for
every 6 pounds you lose.
Cholesterol Buster: Quit Smoking
• Giving up tobacco is
tough, but here's one
more reason to try. When
you stop smoking, your
good cholesterol is likely
to improve by as much as
10%. You may be more
successful if you combine
several smoking
cessation strategies. Talk
to your doctor about
which options are best for
you.
Cholesterol Buster: Exercise
• If you're healthy but not very
active, starting an aerobic
exercise program could
increase your good cholesterol
by 5% in the first two months.
Regular exercise also lowers
bad cholesterol. Choose an
activity that boosts your heart
rate, such as running,
swimming, or walking briskly,
and aim for at least 30 minutes
on most days of the week. It
doesn't have to be 30
continuous minutes; two 15-
minute walks works just as
well.
Treatment: Medications
• If high cholesterol runs in your
family, diet and exercise may
not be enough to get your
numbers where you want
them. In that case, medication
can give your cholesterol
levels an extra nudge. Statins
are usually the first choice.
They block the production of
cholesterol in the liver. Other
options include cholesterol
absorption inhibitors, bile acid
resins, and fibrates. Your
doctor may recommend a
combination of these
medications.
Treatment: Supplements
• Certain dietary supplements
may also improve cholesterol
levels. These include flaxseed
oil, fish oil, and plant sterols,
such as beta-sitosterol.
Prescription niacin, a b-
complex vitamin, has been
found to raise good cholesterol
while reducing bad cholesterol.
Niacin found in ordinary
supplements should not be
used to lower cholesterol.
Herbal Remedies
Some studies suggest
garlic can knock a few
percentage points off total
cholesterol. But garlic
pills can have side effects
and may interact with
medications. Other herbs
that may reduce
cholesterol include:
• Fenugreek seeds
• Artichoke leaf extract
• Yarrow
• Holy basil
How Low Should You Go?
• Many people are able to lower
cholesterol levels through a
combination of medication and
lifestyle changes. But how low
is low enough? For people with
diabetes or a high risk of
developing heart disease, an
LDL score of less than 100 is
desirable. If you already have
heart disease or coronary
artery disease, some doctors
recommend reducing LDL to
70 or lower.
Can the Damage Be Undone?
• It takes years for high
cholesterol to clog the arteries
with plaque. But there is
evidence that atherosclerosis
can be reversed, at least to
some degree. Dean Ornish,
MD, has published several
studies showing that a low-fat
vegetarian diet, stress
management, and moderate
exercise can chip away at the
build-up inside the coronary
arteries. Other research
supports the idea that big
drops in cholesterol can
somewhat help open clogged
arteries.
What is Cholesterol? Understanding the Types and How to Lower Your Levels

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What is Cholesterol? Understanding the Types and How to Lower Your Levels

  • 1. What Is Cholesterol? • We may associate cholesterol with fatty foods, but most of the waxy substance is made by our own bodies. The liver produces 75% of the cholesterol that circulates in our blood. The other 25% comes from food. At normal levels, cholesterol actually plays an important role in helping cells do their jobs. But cholesterol levels are precariously high in more than 100 million Indians.
  • 2. Symptoms of High Cholesterol • High cholesterol does not cause any symptoms. But it does cause damage deep within the body. Over time, too much cholesterol may lead to a buildup of plaque inside the arteries. Known as atherosclerosis, this condition narrows the space available for blood flow and can trigger heart disease. The good news is high cholesterol is simple to detect, and there are many ways to bring it down.
  • 3. Cholesterol Testing • People older than 20 should have their cholesterol levels checked at least once every five years. This is done with a simple blood test known as a fasting lipoprotein profile. It measures the different forms of cholesterol that are circulating in your blood after you avoid eating for 9 to 12 hours. The results show your levels of "bad" cholesterol, "good" cholesterol, and triglycerides.
  • 4. "Bad" Cholesterol • Most of the cholesterol in the blood is carried by proteins called low density lipoproteins or LDL. This is known as the bad cholesterol because it combines with other substances to clog the arteries. A diet high in saturated fats and trans fats tends to raise the level of LDL cholesterol. For most people, an LDL score below 100 is healthy, but people with heart disease may need to aim even lower.
  • 5. "Good" Cholesterol • Up to a third of blood cholesterol is carried by high- density lipoproteins or HDL. This is called good cholesterol because it helps remove bad cholesterol, preventing it from building up inside the arteries. The higher the level of HDL cholesterol, the better. People with too little are more likely to develop heart disease. Eating healthy fats, such as olive oil, may help boost HDL cholesterol.
  • 6. Triglycerides • The body converts excess calories, sugar, and alcohol into triglycerides, a type of fat that is carried in the blood and stored in fat cells throughout the body. People who are overweight, inactive, smokers, or heavy drinkers tend to have high triglycerides, as do those who eat a very high-carb diet. A triglycerides score of 150 or higher puts you at risk for metabolic syndrome, which is linked to heart disease and diabetes.
  • 7. Total Cholesterol • Total cholesterol measures the combination of LDL, HDL, and VLDL (very low density lipoprotein) in your bloodstream. VLDL is a precursor of LDL, the bad cholesterol. A total cholesterol score of under 200 is considered healthy in most cases. People who score in the "high" range have an increased risk of developing heart disease compared to those who score below 200.
  • 8. Cholesterol Ratio • To calculate your cholesterol ratio, divide your total cholesterol by your HDL cholesterol. For example, a total score of 200 divided by an HDL score of 50 equals a cholesterol ratio of 4 to 1. Doctors recommend maintaining a ratio of 4 to 1 or lower. The smaller the ratio, the better. While this figure is useful in estimating heart disease risk, it's not as important in guiding treatment. Doctors look at total cholesterol, HDL cholesterol, and LDL cholesterol to determine treatment.
  • 9. Cholesterol in Food • Cholesterol-rich foods, like eggs, shrimp, and lobster are no longer completely forbidden. Research shows that the cholesterol we eat has only a small effect on blood cholesterol levels for most people. A few people are "responders," whose blood levels spike up after eating eggs. But for most, saturated fat and trans fats are bigger concerns. Daily cholesterol limits are 300 mg for healthy people and 200 mg for those at higher risk. One egg has 186 mg of cholesterol.
  • 10. Cholesterol and Family History • Cholesterol comes from two sources -- the body and food -- and either one can contribute to high cholesterol. Some people inherit genes that trigger too much cholesterol production. For others, diet is the main culprit. Saturated fat and cholesterol occur in animal-based foods, including meat, eggs, and dairy products made with milk. In many cases, high cholesterol stems from a combination of diet and genetics.
  • 11. What Boosts Your Risk? Several factors can make you more likely to develop high cholesterol: • A diet high in saturated fats and cholesterol • A family history of high cholesterol • Being overweight or obese • Getting older
  • 12. Cholesterol and Gender • Until menopause, women typically have lower total cholesterol levels than men of the same age. They also have higher levels of HDL cholesterol, the good kind. One reason is estrogen: The female sex hormone raises the level of HDL cholesterol. Estrogen production peaks during the childbearing years and drops off during menopause. After age 55, a woman's risk of developing high cholesterol begins to climb.
  • 13. Cholesterol and Children • There's evidence that cholesterol can begin clogging the arteries during childhood, leading to atherosclerosis and heart disease later in life. The American Heart Association recommends kids and teenagers with high cholesterol take steps to bring it down. Ideally, total cholesterol should be below 170 in people ages 2 to 19.
  • 14. Why High Cholesterol Matters • High cholesterol is one of the major risk factors for coronary artery disease, heart attacks, and strokes. It also appears to boost the risk of Alzheimer's disease. As we saw earlier, high cholesterol leads to a buildup of plaque that narrows the arteries. This is dangerous because it can restrict blood flow. If the blood supply to a part of the heart or brain is completely cut off, the result is a heart attack or stroke.
  • 15. Cholesterol Buster: Eat More Fiber • Diet changes offer a powerful way to fight high cholesterol. If you've ever wondered why some cereals claim to be heart- healthy, it's the fiber. The soluble fiber found in many foods helps reduce LDL, the bad cholesterol. Good sources of soluble fiber include whole-grain breads and cereals, oatmeal, fruits, dried fruits, vegetables, and legumes such as kidney beans.
  • 16. Cholesterol Buster: Know Your Fats • No more than 35% of your daily calories should come from fat. But not all fats are equal. Saturated fats -- from animal products and tropical oils -- raise LDL cholesterol. Trans fats carry a double-whammy, boosting bad cholesterol, while lowering the good kind. These two bad fats are found in many baked goods, fried foods (doughnuts, french fries, chips), stick margarine, and cookies. Unsaturated fats may lower LDL when combined with other healthy diet changes. They're found in avocados, olive oil, and peanut oil.
  • 17. Cholesterol Buster: Smart Protein • Meat and full-fat milk offer plenty of protein, but they are also major sources of cholesterol. You may be able to reduce LDL cholesterol by switching to soy protein, such as tofu, at some meals. Fish is another great choice. It's rich in omega-3 fatty acids, which can improve cholesterol levels. The American Heart Association recommends eating fish at least twice a week.
  • 18. Cholesterol Buster: Low-Carb Diet • There's growing evidence that low-carb diets may be better than low-fat diets for improving cholesterol levels. In a two-year study funded by the National Institutes of Health, people who followed a low-carb plan had significantly better HDL (good cholesterol) levels than those who followed a low-fat plan.
  • 19. Cholesterol Buster: Lose Weight • If you're overweight, talk to your doctor about beginning a weight loss program. Losing weight can help you reduce your levels of triglycerides, LDL, and total cholesterol. Shedding even a few pounds can also boost your good cholesterol level -- it tends to go up 1 point for every 6 pounds you lose.
  • 20. Cholesterol Buster: Quit Smoking • Giving up tobacco is tough, but here's one more reason to try. When you stop smoking, your good cholesterol is likely to improve by as much as 10%. You may be more successful if you combine several smoking cessation strategies. Talk to your doctor about which options are best for you.
  • 21. Cholesterol Buster: Exercise • If you're healthy but not very active, starting an aerobic exercise program could increase your good cholesterol by 5% in the first two months. Regular exercise also lowers bad cholesterol. Choose an activity that boosts your heart rate, such as running, swimming, or walking briskly, and aim for at least 30 minutes on most days of the week. It doesn't have to be 30 continuous minutes; two 15- minute walks works just as well.
  • 22. Treatment: Medications • If high cholesterol runs in your family, diet and exercise may not be enough to get your numbers where you want them. In that case, medication can give your cholesterol levels an extra nudge. Statins are usually the first choice. They block the production of cholesterol in the liver. Other options include cholesterol absorption inhibitors, bile acid resins, and fibrates. Your doctor may recommend a combination of these medications.
  • 23. Treatment: Supplements • Certain dietary supplements may also improve cholesterol levels. These include flaxseed oil, fish oil, and plant sterols, such as beta-sitosterol. Prescription niacin, a b- complex vitamin, has been found to raise good cholesterol while reducing bad cholesterol. Niacin found in ordinary supplements should not be used to lower cholesterol.
  • 24. Herbal Remedies Some studies suggest garlic can knock a few percentage points off total cholesterol. But garlic pills can have side effects and may interact with medications. Other herbs that may reduce cholesterol include: • Fenugreek seeds • Artichoke leaf extract • Yarrow • Holy basil
  • 25. How Low Should You Go? • Many people are able to lower cholesterol levels through a combination of medication and lifestyle changes. But how low is low enough? For people with diabetes or a high risk of developing heart disease, an LDL score of less than 100 is desirable. If you already have heart disease or coronary artery disease, some doctors recommend reducing LDL to 70 or lower.
  • 26. Can the Damage Be Undone? • It takes years for high cholesterol to clog the arteries with plaque. But there is evidence that atherosclerosis can be reversed, at least to some degree. Dean Ornish, MD, has published several studies showing that a low-fat vegetarian diet, stress management, and moderate exercise can chip away at the build-up inside the coronary arteries. Other research supports the idea that big drops in cholesterol can somewhat help open clogged arteries.