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PRESENTING
LUNG CANCER
         BY
 Denmark Guillermo, RN
Lung Cancer

Uncontrolled growth of malignant cells in
 one or both lungs and tracheo-bronchial
 tree
 A result of repeated carcinogenic irritation
 causing increased rates of cell replication
Proliferation of abnormal cells leads to
 hyperplasia, dysplasia or carcinoma
Picture of the Lungs
What is the Function of the Lungs?

                   The lungs consist of five lobes,
                    three in the right lung and two in
                    the left lung

                   Most cells in the lung are epithelial
                    cells, which line the breathing
                    passages and produce mucus,
                    which lubricates and protects the
                    lungs

                   The main function of the lungs is
                    to allow oxygen from the air to
                    enter the bloodstream for delivery
                    to the rest of the body
Normal Cell
 Division
Two types of cell Cycle Mechanisms
CDK cycle mechanism-
 Ensures well delineated transition bet.
 Cell cycle stages

Check- point control mechanism-
 sense flaws in DNA replication and
 chromosome segregation
Risk factors of Lung Cancer

Radiation Exposure
Smoking
Environmental/ Occupational
 Exposure
  Asbestos
  Radon
  Passive smoke
Smoking Facts
 Tobacco use is the
  leading cause of lung
  cancer
 87% of lung cancers
  are related to smoking
 Risk related to:
    age of smoking onset
    amount smoked
    gender
    product smoked
    depth of inhalation
Pathophysiology of
   Lung Cancer
Smoking –
   Chronic
(Carcinogens)
Injury to
Inhalation of
                Pulmonary and
   Smoke           Alveolar
                  Epithelium

     Destruction of
     Walls Between
      the Alveoli
Inhalation of
   Smoke


         Defense
     Mechanism of the
       Lung Lose
      Effectiveness
Carcinogen
 Penetrate
 the lower
  Airways




             Lower Airways
             Inflammations
Carcinogens
               are Lodged in
                 the Lungs
Narrow
Airways

                Increase
                 Sputum
               Production
     Dyspnea
INFECTION




                        Pleuritic Chest
FEVER                        Pain


        SWEATS      Chills
Injury to Pulmonary and Alveolar
            Epithelium




                  Localized
                lesion in the
                 lung area
Bleeding will
occur(hemoptysis)
Destruction of Walls Between
          the Alveoli


              Increase
            “DEAD SPACE”
          (Areas That Do Not
          Participate in Gas or
           Blood Exchange)
Decrease o2
   Increase     supply to the
  Respiratory      blood
     Rate
(Compensatory
  Mechanism)

                   fatigue
Cell cycle
mechanism
 alteration
Undetected
 flaws in DNA
replication and
 chromosome
  segregation
uncontrolled
defective cell
 proliferation
Tumor
formation(cancer
 cells formation)
TUMOR
(Cancer Cells)
METASTASI
    S
1
    Obstruction
       of the
      Regional
    Lymph Node
2


      Direct
    Extension
    to larynx
3


    Compression
         of
     Esophagus
4


    Compression
     of Superior
     Vena Cava
5


    Obstruction
    of Venous
    Blood Flow
Obstruction
  of the
 Regional
  Lymph               Impaired
   Node                 lymph
                      Drainage




    ex.(Mediastinal
        Lymph)
Diaphragm Paralysis
                (Phrenic Nerve
Vocal Cord       Compression)
 Paralysis
Direct
         Extension to
          the larynx




 Laryngeal
   Nerve          Hoarseness
Compression
Compression
      of Esophagus




Dysphagia
Compression
 of Superior
 Vena Cava




        Superior Vena Cava
            Syndrome
Obstruction of
Venous Blood
    Flow
1                   2
    Shortness of          Swelling
      Breath            (Facial Arm
                         and Truck)




3   Distension of   4    Chest
      Thoracic
        Vein             Pain
Syndromes/Symptoms secondary to
regional metastases:

 1.Esophageal compression dysphagia
 2.Laryngeal nerve paralysis hoarseness
 3.Symptomatic nerve paralysis Horner’s
 syndrome
 4.Cervical/thoracic nerve invasion
 5.Pancoast syndrome
 6.Lymphatic obstruction pleural effusion
 7.Vascular obstruction SVC syndrome
 8.Pericardial/cardiac extension effusion,
 tamponade
Where does it travel?


Lymph Nodes, Brain, Liver, Adrenal,
   Gland, Bones

40% of metastasis occurs in the
    Adrenal Gland
How is Lung Cancer Treated?
1.Treatment depends on the stage and type
  of lung cancer
2.Surgery
3.Radiation therapy
4.Chemotherapy (options include a
  combination of drugs)
5.Targeted therapy
6.Lung cancer is usually treated with a
  combination of therapies
Cancer Treatment: Surgery

1.The tumor and the nearby lymph nodes in
  the chest are typically removed to offer the
  best chance for cure
2.For non-small cell lung cancer, a
  lobectomy (removal of the entire lobe
  where the tumor is located), has shown to
  be most effective
3.Surgery may not be possible in some
  patients
Cancer Treatment: Chemotherapy

1.Drugs used to kill cancer cells
2.A combination of medications is often
  used
3.May be prescribed before or after surgery,
  or before, during, or after radiation therapy
4.Can improve survival and lessen lung
  cancer symptoms in all patients, even
  those with widespread lung cancer
Cancer Treatment: Radiation
Therapy
1.The use of high-energy x-rays or other
  particles to destroy cancer cells
2.Side effects include fatigue, malaise
  (feeling unwell), loss of appetite, and skin
  irritation at the treatment site
3.Radiation pneumonitis is the irritation and
  inflammation of the lung; occurs in 15% of
  patients
4.It is important that the radiation treatments
  avoid the healthy parts of the lung
Lung Cancer Staging
1.Staging is a way of describing a cancer,
  such as the size of the tumor and where it
  has spread
2.Staging is the most important tool doctors
  have to determine a patient’s prognosis
3.The type of treatment a person receives
  depends on the stage of the cancer
4.Staging is different for non-small cell lung
  cancer and small cell lung cancer
Stage I Non-Small Cell Lung Cancer
                   1.Cancer is found
                     only in the lung
                   2.Surgical removal
                     recommended
                   3.Radiation therapy
                     and/or
                     chemotherapy
                     may also be used
Stage II Non-Small Cell Lung Cancer
                  1.The cancer has spread
                    to lymph nodes in the
                    lung
                  2.Treatment is surgery to
                    remove the tumor and
                    nearby lymph nodes
                  3.Chemotherapy
                    recommended; radiation
                    therapy sometimes
                    given after
                    chemotherapy
Stage III Non-Small Cell Lung
Cancer
                 1.The cancer has spread to the lymph
                     nodes located in the center of the chest,
                     outside the lung
                 2.Stage IIIA cancer has spread to lymph
                     nodes in the chest, on the same side
                     where the cancer originated
                 3. Stage IIIB cancer has spread to lymph
                     nodes on the opposite side of the chest,
                     under the collarbone, or the pleura
                     (lining of the chest cavity)
                 4.Surgery or radiation therapy with
                     chemotherapy recommended for stage
                     IIIA
                 5.Chemotherapy and sometimes radiation
                     therapy recommended for stage IIIB
Stage IV Non-Small Cell Lung Cancer

                   1.The cancer has spread to
                      different lobes of the lung
                      or to other organs, such
                      as the brain, bones, and
                      liver
                    2.Stage IV non-small cell
                      lung cancer is treated with
                      chemotherapy
Small Cell Lung Cancer–All Stages
1.Patients with limited stage (confined to one area
  of the chest) small cell lung cancer are treated
  with simultaneous radiation therapy and
  chemotherapy
2.Patients with extensive stage (not confined to
  one area of the chest) small cell lung cancer are
  treated with chemotherapy only
3.Because small cell lung cancer can spread to the
  brain, preventative radiation therapy to the brain
  is routinely recommended to all patients whose
  tumors disappear following chemotherapy and
  radiation therapy
Nursing responsibilities
Nursing Management during Diagnostic
  Phase
 1. Obtain nursing history(cough ,
  dyspnea , pain or recurrent infection)
 2. focus on emotional aspect of
  assessment
 3. Educate the client with the required
  physical care and scheduled examinations
 4. Assist to cope with anxiety
Nursing management during
Treatment Phase
1. Put great emphasis on assessment of
   respiratory system to determine ability of
   the client to cope up with surgical
   intervention
2. Clients with impaired pulmonary function
   may be treated with antibiotics,
   bronchodilating medications, and
   supervised breathing exercise
3. Encouraged patient to avoid smoking
  during preoperative because smoking will
  increase pulmonary secretions and
  decrease blood oxygen saturation.
4.Assess the clients understanding and
  further information as needed
5.Explain the procedure to be done and the
  expected outcome
6. Explain and demonstrate post – op
  exercises such as leg exercise and correct
  posture
Postoperative assessments

1.Monitor for signs and symptoms of
  respiratory failure
2. Monitor for signs of tension
  pneumothorax
3. Observe for subcutaneous emphysema
  around incision and in chest and neck
4.Monitor for signs of pulmonary embolism
5. Assess dressing
6. Assess drainage
7. Assess breath sound before and after
  coughing
8. Administer pain medication as ordered
9. Allow adequate rest periods
10. Provide client opportunity to ventilate
  feelings
Nursing Interventions during
Terminal Phase
1. Physical support such as giving of pain
  medication should be given great
  emphasis.
2.Help the client to ventilate thoughts and
  feelings
3. Assist significant others to cope with the
  situation
Quit
Smoking!
!!!!!

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Lung cancer

  • 1. PRESENTING LUNG CANCER BY Denmark Guillermo, RN
  • 2. Lung Cancer Uncontrolled growth of malignant cells in one or both lungs and tracheo-bronchial tree  A result of repeated carcinogenic irritation causing increased rates of cell replication Proliferation of abnormal cells leads to hyperplasia, dysplasia or carcinoma
  • 4. What is the Function of the Lungs?  The lungs consist of five lobes, three in the right lung and two in the left lung  Most cells in the lung are epithelial cells, which line the breathing passages and produce mucus, which lubricates and protects the lungs  The main function of the lungs is to allow oxygen from the air to enter the bloodstream for delivery to the rest of the body
  • 6.
  • 7. Two types of cell Cycle Mechanisms CDK cycle mechanism- Ensures well delineated transition bet. Cell cycle stages Check- point control mechanism- sense flaws in DNA replication and chromosome segregation
  • 8. Risk factors of Lung Cancer Radiation Exposure Smoking Environmental/ Occupational Exposure Asbestos Radon Passive smoke
  • 9. Smoking Facts  Tobacco use is the leading cause of lung cancer  87% of lung cancers are related to smoking  Risk related to:  age of smoking onset  amount smoked  gender  product smoked  depth of inhalation
  • 10. Pathophysiology of Lung Cancer
  • 11. Smoking – Chronic (Carcinogens)
  • 12. Injury to Inhalation of Pulmonary and Smoke Alveolar Epithelium Destruction of Walls Between the Alveoli
  • 13. Inhalation of Smoke Defense Mechanism of the Lung Lose Effectiveness
  • 14. Carcinogen Penetrate the lower Airways Lower Airways Inflammations
  • 15. Carcinogens are Lodged in the Lungs Narrow Airways Increase Sputum Production Dyspnea
  • 16. INFECTION Pleuritic Chest FEVER Pain SWEATS Chills
  • 17. Injury to Pulmonary and Alveolar Epithelium Localized lesion in the lung area
  • 19. Destruction of Walls Between the Alveoli Increase “DEAD SPACE” (Areas That Do Not Participate in Gas or Blood Exchange)
  • 20. Decrease o2 Increase supply to the Respiratory blood Rate (Compensatory Mechanism) fatigue
  • 22. Undetected flaws in DNA replication and chromosome segregation
  • 27. 1 Obstruction of the Regional Lymph Node
  • 28. 2 Direct Extension to larynx
  • 29. 3 Compression of Esophagus
  • 30. 4 Compression of Superior Vena Cava
  • 31. 5 Obstruction of Venous Blood Flow
  • 32. Obstruction of the Regional Lymph Impaired Node lymph Drainage ex.(Mediastinal Lymph)
  • 33. Diaphragm Paralysis (Phrenic Nerve Vocal Cord Compression) Paralysis
  • 34. Direct Extension to the larynx Laryngeal Nerve Hoarseness Compression
  • 35. Compression of Esophagus Dysphagia
  • 36. Compression of Superior Vena Cava Superior Vena Cava Syndrome
  • 38. 1 2 Shortness of Swelling Breath (Facial Arm and Truck) 3 Distension of 4 Chest Thoracic Vein Pain
  • 39. Syndromes/Symptoms secondary to regional metastases: 1.Esophageal compression dysphagia 2.Laryngeal nerve paralysis hoarseness 3.Symptomatic nerve paralysis Horner’s syndrome 4.Cervical/thoracic nerve invasion 5.Pancoast syndrome 6.Lymphatic obstruction pleural effusion 7.Vascular obstruction SVC syndrome 8.Pericardial/cardiac extension effusion, tamponade
  • 40. Where does it travel? Lymph Nodes, Brain, Liver, Adrenal, Gland, Bones 40% of metastasis occurs in the Adrenal Gland
  • 41. How is Lung Cancer Treated? 1.Treatment depends on the stage and type of lung cancer 2.Surgery 3.Radiation therapy 4.Chemotherapy (options include a combination of drugs) 5.Targeted therapy 6.Lung cancer is usually treated with a combination of therapies
  • 42. Cancer Treatment: Surgery 1.The tumor and the nearby lymph nodes in the chest are typically removed to offer the best chance for cure 2.For non-small cell lung cancer, a lobectomy (removal of the entire lobe where the tumor is located), has shown to be most effective 3.Surgery may not be possible in some patients
  • 43. Cancer Treatment: Chemotherapy 1.Drugs used to kill cancer cells 2.A combination of medications is often used 3.May be prescribed before or after surgery, or before, during, or after radiation therapy 4.Can improve survival and lessen lung cancer symptoms in all patients, even those with widespread lung cancer
  • 44. Cancer Treatment: Radiation Therapy 1.The use of high-energy x-rays or other particles to destroy cancer cells 2.Side effects include fatigue, malaise (feeling unwell), loss of appetite, and skin irritation at the treatment site 3.Radiation pneumonitis is the irritation and inflammation of the lung; occurs in 15% of patients 4.It is important that the radiation treatments avoid the healthy parts of the lung
  • 45. Lung Cancer Staging 1.Staging is a way of describing a cancer, such as the size of the tumor and where it has spread 2.Staging is the most important tool doctors have to determine a patient’s prognosis 3.The type of treatment a person receives depends on the stage of the cancer 4.Staging is different for non-small cell lung cancer and small cell lung cancer
  • 46. Stage I Non-Small Cell Lung Cancer 1.Cancer is found only in the lung 2.Surgical removal recommended 3.Radiation therapy and/or chemotherapy may also be used
  • 47. Stage II Non-Small Cell Lung Cancer 1.The cancer has spread to lymph nodes in the lung 2.Treatment is surgery to remove the tumor and nearby lymph nodes 3.Chemotherapy recommended; radiation therapy sometimes given after chemotherapy
  • 48. Stage III Non-Small Cell Lung Cancer 1.The cancer has spread to the lymph nodes located in the center of the chest, outside the lung 2.Stage IIIA cancer has spread to lymph nodes in the chest, on the same side where the cancer originated 3. Stage IIIB cancer has spread to lymph nodes on the opposite side of the chest, under the collarbone, or the pleura (lining of the chest cavity) 4.Surgery or radiation therapy with chemotherapy recommended for stage IIIA 5.Chemotherapy and sometimes radiation therapy recommended for stage IIIB
  • 49. Stage IV Non-Small Cell Lung Cancer 1.The cancer has spread to different lobes of the lung or to other organs, such as the brain, bones, and liver 2.Stage IV non-small cell lung cancer is treated with chemotherapy
  • 50. Small Cell Lung Cancer–All Stages 1.Patients with limited stage (confined to one area of the chest) small cell lung cancer are treated with simultaneous radiation therapy and chemotherapy 2.Patients with extensive stage (not confined to one area of the chest) small cell lung cancer are treated with chemotherapy only 3.Because small cell lung cancer can spread to the brain, preventative radiation therapy to the brain is routinely recommended to all patients whose tumors disappear following chemotherapy and radiation therapy
  • 51. Nursing responsibilities Nursing Management during Diagnostic Phase 1. Obtain nursing history(cough , dyspnea , pain or recurrent infection) 2. focus on emotional aspect of assessment 3. Educate the client with the required physical care and scheduled examinations 4. Assist to cope with anxiety
  • 52. Nursing management during Treatment Phase 1. Put great emphasis on assessment of respiratory system to determine ability of the client to cope up with surgical intervention 2. Clients with impaired pulmonary function may be treated with antibiotics, bronchodilating medications, and supervised breathing exercise
  • 53. 3. Encouraged patient to avoid smoking during preoperative because smoking will increase pulmonary secretions and decrease blood oxygen saturation. 4.Assess the clients understanding and further information as needed 5.Explain the procedure to be done and the expected outcome 6. Explain and demonstrate post – op exercises such as leg exercise and correct posture
  • 54. Postoperative assessments 1.Monitor for signs and symptoms of respiratory failure 2. Monitor for signs of tension pneumothorax 3. Observe for subcutaneous emphysema around incision and in chest and neck 4.Monitor for signs of pulmonary embolism 5. Assess dressing 6. Assess drainage
  • 55. 7. Assess breath sound before and after coughing 8. Administer pain medication as ordered 9. Allow adequate rest periods 10. Provide client opportunity to ventilate feelings
  • 56. Nursing Interventions during Terminal Phase 1. Physical support such as giving of pain medication should be given great emphasis. 2.Help the client to ventilate thoughts and feelings 3. Assist significant others to cope with the situation