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Airway pH: Measuring Aerosolized Acidity and Alkalinity New Product Technology Review
1974 The Johnson – DeMeester Score
[object Object],San Diego based Endonetics Young engineer / inventor  Ross Tsukashima Medical Advisor  Dr. Tom DeMeester Sold to Medtronics
2006  Restech patented Oropharyngeal Probe ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object]
Esophageal pH Probe Placement Esophagus (20-24 cm) Upper Esophageal Sphincter Lower Esophageal Sphincter Dual Channel Catheter
Sensor Design of Esophageal pH Catheters   Reference Sensor ,[object Object],[object Object],[object Object],[object Object],Traditional Dual Channel Probe
Problems Using Esophageal Sensor in the Pharynx ,[object Object],Esophagus (20-24 cm) Upper Esophageal Sphincter Lower Esophageal Sphincter »  If the 2nd channel is placed  higher it dries out due to  air contact »  Sensor can be fouled  by mucus »  Mucosal contact can  mask reflux events
Restech Sensor Technology  »  Coplanar Ionic Bridge pH sensor »  Does not require immersion in Liquid »  Designed to work in the Oropharynx
Sensitivity Improvements ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Antimony Reference
Manometry Free Positioning ,[object Object]
Data Feed Adapter ,[object Object],[object Object],[object Object],[object Object]
 
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object]
 
 
 
 
 
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
 
Current Diagnostic Techniques ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
 
Normal Study
Patient 1 ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Patient 1 ,[object Object],[object Object],[object Object],[object Object],[object Object]
Patient 1 ,[object Object],[object Object],[object Object]
Patient 2 ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Patient 2 ,[object Object],[object Object]
Patient 2 ,[object Object],[object Object],[object Object]
Application of Ambulatory Supraesophageal pH Probe Monitoring in Infants and Children ,[object Object],[object Object],[object Object]
Pulmonary Manifestations of  Gastroesophageal Reflux Disease   Apnea   Aspiration Pneumonia   Atelectasis   Bronchiectasis   Bronchitis   Chronic Asthma   Hemoptysis   Hoarseness or Laryngitis   Pulmonary Fibrosis   Seizures relate to Hypoxia
Age 3 months ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Age 4 months ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Age 15 months ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Age 5 years ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
 
 
 
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Clinical Value of Restech’s Dx-pH System? ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Exposure / Penetration 2007 North America Respiratory Devices  Product Innovation of the Year Award Award Recipient: Respiratory Technology Corporation Presentations in GERD Reviewed by Joel E. Richter, MD Richard L. Evans Professor of Medicine Chairman, Department of Medicine Temple University School of Medicine Dx–pH Measurement System:  A Sensitive Device for Detecting Liquid and Aerosolized Supraesophageal Gastric Reflux
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Restech Presentation

  • 1. Airway pH: Measuring Aerosolized Acidity and Alkalinity New Product Technology Review
  • 2. 1974 The Johnson – DeMeester Score
  • 3.
  • 4.
  • 5.
  • 6. Esophageal pH Probe Placement Esophagus (20-24 cm) Upper Esophageal Sphincter Lower Esophageal Sphincter Dual Channel Catheter
  • 7.
  • 8.
  • 9. Restech Sensor Technology » Coplanar Ionic Bridge pH sensor » Does not require immersion in Liquid » Designed to work in the Oropharynx
  • 10.
  • 11.
  • 12.
  • 13.  
  • 14.
  • 15.
  • 16.  
  • 17.  
  • 18.  
  • 19.  
  • 20.  
  • 21.
  • 22.  
  • 23.
  • 24.  
  • 26.
  • 27.
  • 28.
  • 29.
  • 30.
  • 31.
  • 32.
  • 33. Pulmonary Manifestations of Gastroesophageal Reflux Disease  Apnea  Aspiration Pneumonia  Atelectasis  Bronchiectasis  Bronchitis  Chronic Asthma  Hemoptysis  Hoarseness or Laryngitis  Pulmonary Fibrosis  Seizures relate to Hypoxia
  • 34.
  • 35.
  • 36.
  • 37.
  • 38.  
  • 39.  
  • 40.  
  • 41.
  • 42.
  • 43. Exposure / Penetration 2007 North America Respiratory Devices Product Innovation of the Year Award Award Recipient: Respiratory Technology Corporation Presentations in GERD Reviewed by Joel E. Richter, MD Richard L. Evans Professor of Medicine Chairman, Department of Medicine Temple University School of Medicine Dx–pH Measurement System: A Sensitive Device for Detecting Liquid and Aerosolized Supraesophageal Gastric Reflux

Editor's Notes

  1. Toturing patients – Electrical ground burned the forearm of a patient
  2. Esophageal pH catheters not validated for use in pharynx (n o accepted normative pharyngeal data in children) resulting in high rate of false negatives when used in the pharynx (poor sensitivity) Access to and acceptance by Pediatric Gastroenterologists of LPR Tx Trial: Empiric trial with PPIs/H2 Blockers Restech probe: The only commercially available pH probe that can detect aerosolized reflux above the UES
  3. Aug 07: +LPR; Aug 07: AM/PM marked LPR treated with Prevacid [dosage?]
  4. Dec 07: Repeat study performed on therapy. Normal study (mark graphs with meal periods like Bravo SW does)
  5. Positive Supine LPR Treatment w/ Pepcid (dose?)
  6. Repeat 24 hour pH study - Normal study on Rx
  7. Atelectasis is the collapse of part or all of a lung. It is caused by a blockage of the air passages (bronchus or bronchioles) or by pressure on the lung. Bronchiectasis is an irreversible widening (dilation) of portions of the breathing tubes or airways (bronchi) resulting from damage to the airway wall. The most common cause is severe or repeated respiratory infections. Hemoptysis or haemoptysis (see American and British spelling differences ) is the expectoration ( coughing up) of blood or of blood-stained sputum from the bronchi , larynx , trachea , or lungs (e.g. in tuberculosis or other respiratory infections). http://www.ctccomm.com/Publishing/gastro/GastroSS1104gerd.html