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5
                                                   Finding solutions
                                                   to maternal
                                                   and perinatal
                                                   mortality

Before you begin this unit, please take the         FINDING SOLUTIONS
corresponding test at the end of the book to
assess your knowledge of the subject matter. You
should redo the test after you’ve worked through    5-1 How can you find solutions to maternal
the unit, to evaluate what you have learned.        and perinatal deaths?

 Objectives                                         There are a number of steps which are needed:
                                                    1. Specific avoidable factors, missed
 When you have completed this unit you                 opportunities and substandard care have to
                                                       be identified.
 should be able to:
                                                    2. You need to know where and how to look
 • Find solutions to the common causes of              for answers to these problems.
   maternal and perinatal deaths.                   3. Answers have to be found.
 • List the potentially avoidable causes of         4. Changes have to be introduced.
   maternal death.
                                                    5-2 What is an avoidable factor?
 • Take steps to prevent maternal death.
 • List the potentially avoidable causes of         An avoidable (or modifiable) factor is
                                                    something which may have prevented the
   perinatal death.
                                                    death, e.g. a woman not immediately going to
 • Take steps to avoid the primary causes of        a clinic or hospital when abdominal pain with
   perinatal death.                                 vaginal bleeding occurs during pregnancy.
 • Improve the care of newborn infants.
                                                    Many avoidable factors are due to missed
                                                    opportunities.


                                                     An avoidable factor may have prevented a death.
FINDING SOLUTIONS TO MATERNAL AND PERINATAL MOR TALITY          65


5-3 What is a missed opportunity?                        Regular mortality meetings are an excellent
                                                         way of identifying problems and avoidable
A missed opportunity is a chance to provide
                                                         factors.
the correct care which was not taken. The
opportunity was there to provide the correct
management but the opportunity was missed,               5-6 How can avoidable factors be
e.g. failing to measure the blood pressure at an         classified?
antenatal visit or not screening for syphilis.           Avoidable factors can usually be classified into
     NOTE A missed opportunity is when an action or      one of three groups:
     omission by the patient, administration or health   1. Patient related factors.
     worker results in an adverse outcome for the
                                                         2. Health worker related factors.
     mother or infant.
                                                         3. Administrative related factors.
5-4 How can you recognise substandard                    For example, if a fetus or newborn infant dies
care?                                                    of congenital syphilis and the mother failed to
                                                         attend antenatal care, then the avoidable factor
Substandard care means that the care that                would have been patient related. However, if
the patient received fell below the standard             the mother attended the antenatal clinic but
that should have been offered to her. It is              the health care worker failed to screen her
necessary to know what correct care is before            for syphilis or failed to collect the result and
substandard care can be recognised. Care may             treat her, then the avoidable factor would
be substandard because of any of the following:          have been health worker related. Finally, if
1.    The patient did not go for care.                   the mother attended antenatal clinic and the
2.    The facilities were inadequate.                    health worker wanted to screen her for syphilis
3.    Shortage of staffing or poor staff training.       but either transport or the facilities to perform
4.    Staff did not provide the correct care             the test were not available, then the avoidable
      needed.                                            factor would have been administrative related.
Substandard care often leads to avoidable                Some avoidable factors are obviously the
factors and missed opportunities. Therefore,             cause of a maternal or perinatal death while
substandard care, avoidable factors and                  other avoidable factors may have contributed
missed opportunities are usually considered              to the death. Therefore, avoidable factors can
together as problems resulting in poor care.             be divided into probable and possible factors.
Typical examples of substandard care are not             Probable avoidable factors are most important.
monitoring the fetal heart during labour and             Often more than one probably avoidable factor
not suctioning the mouth of a meconium                   will be present.
stained infant before delivering the shoulders.          In addition, some substandard care may not be
                                                         related to the death of an infant. This poor care
5-5 How are problems and avoidable                       can still be discussed at a perinatal mortality
factors identified?                                      meeting although it will not be included as an
Answers cannot be found before the problems              avoidable cause of infant death.
and avoidable factors are identified. As
problems (i.e. causes of maternal and perinatal          5-7 How can avoidable factors related to
deaths) differ between different services,               health workers be subdivided?
hospitals or clinics , the particular problems           1. An honest error, e.g. overestimating the
have to be identified for each service, hospital            gestational age.
or clinic. The avoidable factors associated with         2. An oversight, e.g. forgetting to measure the
each problem may also vary between services,                blood pressure.
hospitals or clinics.
66   SAVING MOTHERS AND BABIES



3. A serious deviation from the accepted            6. Adequate public transport and ambulance
   practice, e.g. failing to see the patient when      services.
   called to do so.
                                                    5-11 How can these changes be made?
5-8 Why is it important to identify the             Once answers are found, there are number of
specific avoidable factor?                          steps which can be taken to introduce changes:
Only when the specific avoidable factor or          1. Notifying the health authorities.
missed opportunity has been identified can          2. Altering protocols in clinics and hospitals.
steps be taken to prevent similar deaths in         3. Improving the frequency and content of
future. If one does not know why the care was          training programmes.
substandard, it would be very difficult to solve    4. Involving the community.
the problem. Finding avoidable factors is an
                                                    However, it is not always easy to introduce
important step in improving care.
                                                    the changes needed to reduce mortality. A
                                                    clear idea of what changes are needed together
5-9 Where can you look for answers?                 with the ability to win the co-operation of the
There are many sources where answers can be         authorities and colleagues are essential.
found once the problem has been identified.
Some answers are easy to find. Unfortunately
some problems still do not have easy or effective   AVOIDABLE FACTORS
answers, e.g. how to prevent pre-eclampsia.
                                                    ASSOCIATED WITH
Answers can usually be found:
                                                    MATERNAL DEATHS
1. By consulting colleagues, especially those
   at referral hospitals.
2. In standard textbooks or journals.               5-12 Can maternal deaths be prevented?
3. In training programmes, such as the              Yes. In almost half of the maternal deaths
   Perinatal Education Programme.                   there was a an avoidable factor (missed
4. By attending courses.                            opportunity for preventing that death or
5. In local management protocols.                   substandard care). Avoidable factors were
6. In provincial or national guidelines.            far more common for direct causes (e.g.
7. On the internet.                                 postpartum haemorrhage) than indirect
                                                    causes (e.g. AIDS). The maternal mortality
5-10 What changes should be made to                 rate is still far too high in South Africa.
reduce mortality rates?
                                                      NOTE Information on causes of maternal death
Changes may be needed in a number of                  and avoidable factors is taken from the Saving
different areas:                                      Mothers 2002–2004: Third report on confidential
                                                      enquiries into maternal deaths in South Africa.
1. Changes in the general community, e.g.
   better housing, education and income.
                                                    5-13 What specific patient related avoidable
2. Changes may be needed in antenatal
                                                    factors are associated with maternal death?
   care, e.g. better booking rates, improved
   screening for hypertension and proteinuria.      1. No, late or inadequate antenatal care.
3. Better patient education, e.g. the               2. Delay in seeking help during labour.
   importance of being aware of fetal               3. Not recognising danger signs and
   movements and danger signs in pregnancy.            symptoms.
4. Improved facilities and staff numbers.           4. Self-induced termination of pregnancy.
5. More continuing training for health
   workers.
FINDING SOLUTIONS TO MATERNAL AND PERINATAL MOR TALITY           67


5-14 What specific health worker related             pregnant woman going to the clinic or hospital
avoidable factors are associated with                as soon as labour starts, or transport my not be
maternal death?                                      available at night.
1. Failure to follow management protocols.
2. Failure to adequately resuscitate acutely ill      Every effort must be made to provide good, early
   women.                                             antenatal care to all pregnant women.
3. Inadequate anaesthetic experience.
4. Poor record keeping.
5. Delay in referral to a level 1 or 2 unit.         5-17 What can be done to improve the care
                                                     provided by health workers?
5-15 What specific administrative related            1. Ensure patient access to adequately staffed
avoidable factors are associated with                   and equipped maternity services.
maternal death?                                      2. Easily understandable management
1. Lack or delay of transport.                          protocols are essential.
2. Lack of intensive care facilities and theatres.   3. Simple referral guidelines are essential.
3. Lack of enough, well trained midwives and         4. A culture of ‘patient friendly’ care must be
   medical officers.                                    developed in all health services.
4. Poor communication between health                 5. A system of good record keeping is
   workers.                                             essential.
5. Lack of management protocols.                     6. Basic training must be improved and on-
6. Inadequate supply of blood.                          going ‘in-service’ education provided.
                                                     7. Adequately staffed facilities for termination
5-16 How can patient related factors be                 of pregnancy, antenatal and labour care
addressed?                                              must be made available in all districts.
                                                     8. Provide good patient transport and
Every effort must be made to get women to               telephone or radio communication.
attend an antenatal care clinic from the time
that pregnancy is confirmed. They must also
be educated to recognise danger symptoms             PREVENTING MATERNAL
and signs and report immediately to a clinic or
hospital as soon as these present:                   DEATHS
1. All pregnant women should be referred
   to an antenatal clinic as soon as their           5-18 What are the key recommendations to
   pregnancy is confirmed. This message              prevent maternal deaths?
   should be made known to all general
   practitioners and other health care               1. Clearly understood protocols are needed to
   professionals.                                       manage conditions which commonly result
2. Pregnant women should plan to be                     in maternal deaths.
   delivered by a skilled attendant and not at       2. A simple set of referral criteria is needed.
   home by a family member.                          3. Adequate staffing and equipment norms
3. Schools, community organisations, radio,             are needed and must be implemented.
   newspapers, magazines and TV should               4. The partogram must be used to monitor
   stress the importance of early antenatal care        every labour.
   and the common danger signs in pregnancy.         5. Blood and regional anaesthesia must be
                                                        available at all institutions where caesarean
Patient related factors often depend on                 sections are performed.
the family and community. For example, a
husband or mother-in-law may prevent a
68   SAVING MOTHERS AND BABIES



6. Midwife Obstetric Clinics (nurse base          6. Combination antiretroviral treatment
   primary care clinics) must be established         and prophylactic co-trimoxazole must
   in urban areas.                                   be made available to all HIV positive
7. Termination of pregnancy services must be         pregnant women who meet the clinical or
   expanded.                                         immunological criteria.
8. Family planning services must be
   supported especially for women over 30
   years or with five or more children.           AVOIDABLE FACTORS
9. A national HIV/AIDS policy must be
   widely implemented.                            ASSOCIATED WITH
                                                  PERINATAL DEATHS
5-19 Should every maternal death be
reported?
                                                  5-21 Can perinatal deaths be prevented?
Yes. The routine reporting and a confidential
enquiry into maternal deaths must be              Yes. In about a quarter of perinatal deaths
expanded to include all maternal deaths,          there was a missed opportunity for preventing
especially in districts, regions and provinces    that death. The commonest avoidable factors
where maternal deaths are still under reported.   are patient related. Unfortunately an avoidable
It is important to include all maternal deaths    factor often cannot be identified because of
from private hospitals and the deaths that        poor notes.
occur at home. Only when the majority of
maternal deaths are reported can a reliable
                                                   The commonest avoidable factors in perinatal
estimate of numbers, causes and avoidable
                                                   death are patient related.
factors be obtained.
                                                    NOTE In the 2003-6 Saving Babies report 16% of
5-20 What national HIV/AIDS policy is               avoidable factors were patient related, 15% health
needed for pregnant women?                          worker related and 67% administrative related.
1. Guidelines on how to manage pregnant
   women who are HIV positive must be             5-22 What are the important patient related
   implemented in all districts.                  factors associated with perinatal death?
2. HIV counselling, testing and prophylactic
                                                  The commonest patient related factors are:
   antiretrovirals must urgently be made
   available at all antenatal clinics in order    1. No attendance, late attendance or irregular
   to reduce the risk of mother-to-child             attendance for antenatal care.
   transmission of HIV.                           2. Inadequate response to decreased fetal
3. Contraceptive advice and the option of            movements.
   terminating the pregnancy should be            3. Inadequate response to rupture of the
   available.                                        membranes.
4. All clinics and hospitals have an obligation   4. Inadequate response to antepartum
   to their staff to ensure that the training        haemorrhage.
   and equipment is available to prevent HIV      5. Delay in seeking medical attention in
   transmission to their staff (e.g. gloves,         labour.
   plastic aprons, glasses or masks, blunt-       Failing to book early and then regularly attend
   tipped needles, skin clips and sharps          antenatal care is the commonest patient
   containers).                                   related factor associate with perinatal death.
5. CD4 screening must be done on all              Little understanding of the importance of
   pregnant women who are HIV positive            antenatal care, long distances to the clinic
FINDING SOLUTIONS TO MATERNAL AND PERINATAL MOR TALITY           69


and inadequate public transport all play             5.   No response to hypertension.
an important role in poor attendance for             6.   Multiple pregnancy not diagnosed.
antenatal care.                                      7.   No response to syphilis serology.
                                                     8.   No response to glycosuria.
                                                     9.   No response to post term pregnancy.
 Inadequate antenatal care is the commonest
 patient related factor associated with perinatal     No response by health workers to antenatal
 death.                                               warning signs is a common avoidable factor
                                                      associated with perinatal death.
Because of poor antenatal clinic attendance,
complications of pregnancy such as
hypertension, decreased fetal growth and             5-26 What are the important health worker
syphilis are not identified and managed.             related factors during labour that are
                                                     associated with perinatal death?
5-23 What are the important administrative
                                                     1. Partogram not used.
related factors associated with perinatal
                                                     2. Fetus not adequately monitored.
death?
                                                     3. Signs of fetal distress not interpreted
1. Transport delays in getting the patient              correctly or ignored.
   between health institutions, e.g. getting a       4. No response to poor progress of labour.
   patient from a clinic to a hospital.              5. Prolonged second stage not managed
2. Lack of adequate screening for syphilis.             correctly.
3. Too few staff or inadequately trained staff.      6. Delay in calling a doctor or referring the
4. Inadequate facilities, especially theatre and        patient.
   neonatal care facilities.
                                                      Inadequate fetal monitoring is the commonest
 Inadequate transport to hospital is the commonest    health worker related factor associated with
 administrative related factor associated with        perinatal death during labour.
 perinatal death.
                                                     5-27 What are the important health worker
                                                     related factors during neonatal care that
5-24 When are health worker related
                                                     are associated with perinatal death?
factors associated with perinatal death?
                                                     1. Inadequate resuscitation.
Health worker related factors may be divided
                                                     2. Inadequate monitoring or management
into:
                                                        plan.
1. Antepartum factors (during pregnancy).            3. Delay in calling for assistance or
2. Intrapartum factors (during labour).                 transferring the infant to a level 2 or 3 unit.
3. Neonatal care factors (care of the infant
   after delivery).
                                                      Inadequate resuscitation of the newborn is an
5-25 What are the important health worker             important avoidable cause of perinatal death.
related factors during antenatal care that
are associated with perinatal death?
                                                     5-28 Which primary causes of neonatal
1.   No response to a poor past obstetric history.   mortality urgently need solutions?
2.   Over or underestimating fetal size.
                                                     The three main primary causes of neonatal
3.   No response to poor uterine growth.
                                                     mortality are:
4.   No response to poor fetal movement.
70   SAVING MOTHERS AND BABIES



1. Spontaneous preterm delivery.                  5-31 What should be done to reduce the
2. Intrapartum hypoxia.                           perinatal mortality rate during labour?
3. Infection.
                                                  1. Correct use of the partogram in all labours.
                                                  2. Correct method of monitoring the fetal
                                                     heart rate.
PREVENTING PERINATAL                              3. Clear protocols of management.
MORTALITY                                         4. Indications for referral.
                                                  5. Adequate equipment that is maintained in
                                                     good working order.
5-29 Can perinatal mortality be prevented?
Yes. Many perinatal deaths can be prevented:      5-32 What should be done to reduce the
                                                  perinatal mortality rate after delivery:
1. We know that the perinatal mortality rate
   in South Africa is far too high.               1. Early diagnosis of birth asphyxia (not
2. We know what the major causes are.                breathing well after delivery).
3. We have identified many of the avoidable       2. Knowledge, skills and equipment for good
   factors.                                          resuscitation.
4. We know how to manage most of these            3. Keep infants dry and warm.
   problems.                                      4. Kangaroo mother care.
                                                  5. Weigh all infants to identify low birth
All that we now need is a clear plan of action       weight infants.
and the will to make the plan work.               6. Good basic newborn care.
                                                  7. Breastfeeding (preferably exclusive
 With simple, good management many of the            breastfeeding).
 perinatal deaths can be prevented.               It is essential that the facilities, necessary
                                                  equipment, management protocols and
                                                  adequate numbers of well trained health
5-30 What should be done to reduce the            workers are available at each clinic and hospital.
perinatal mortality rate during pregnancy?        It is every woman’s right to have a safe delivery.
There are many avoidable factors which can
be addressed to reduce the perinatal mortality.   5-33 Why do some infants die of
The most important are:                           intrapartum hypoxia?

1. Early booking, preferably at the time that     Intrapartum hypoxia means that the fetus did
   pregnancy is diagnosed.                        not receive enough oxygen before delivery
2. On-site screening for syphilis and early       (usually during labour). The main reasons for
   treatment.                                     fetal hypoxia are:
3. Clear protocols for good routine antenatal     1. Placental abruption.
   care and indications for referral.             2. Prolonged or obstructed labour.
4. Fetal growth monitoring using symphysis-       3. Fetal growth restriction or wasting (poor
   fundal height measurements correctly.             fetal growth or weight loss).
5. Teaching mothers to monitor fetal              4. Maternal disease, e.g. pre-eclampsia,
   movements.                                        diabetes and syphilis.
6. Teaching mothers the danger signs of           5. Prolapsed umbilical cord.
   complications.
                                                  The infant may also developed hypoxia after
                                                  delivery if they breathe poorly and are not well
                                                  resuscitated.
FINDING SOLUTIONS TO MATERNAL AND PERINATAL MOR TALITY            71


5-34 What can be done to reduce the risk of           This results in a 1 minute Apgar score of
fetal hypoxia?                                        less than 7. It is essential to detect neonatal
                                                      asphyxia early and to resuscitate the infant
Every effort should be made to prevent fetal
                                                      well. Everyone delivering a newborn infant
hypoxia, and detect fetal distress as soon
                                                      must be able to provide basic resuscitation,
as it develops. Careful monitoring of the
                                                      especially bag and mask ventilation. Oxygen is
fetal condition and the progress of labour
                                                      not necessary for resuscitation.
is essential. The partogram must be used
correctly to detect poor progress of labour.
Fetal hypoxia presents with the signs of fetal            The most important step in newborn
distress, i.e. meconium stained liquor and late           resuscitation is bag and mask ventilation.
fetal heart rate decelerations (and poor beat-
to-beat variability on the cardiotocogram).
                                                      5-37 What can be done to decrease the
                                                      mortality of preterm infants?
 Correct use of the partogram with careful fetal
                                                      While it is difficult to prevent preterm delivery,
 monitoring is essential.                             a lot can be done to prevent the early neonatal
                                                      death of preterm infants:
5-35 How can monitoring of the fetal heart            1. Anticipation
rate during labour be improved?
                                                      •     Giving betamethasone to the mother for
It is impractical to have a cardiotochograph                48 hours before delivery to promote lung
(CTG) recorder in every labour ward.                        maturity.
Therefore, the fetal heart must be                    •     Deliver the mother in a level 2 or 3 hospital.
monitored with an ordinary stethoscope,
                                                      2. Early recognition of neonatal asphyxia
a fetal stethoscope or a hand held Doppler
                                                      and good resuscitation
ultrasound fetal heart rate monitor (a
‘Doptone’). An ultrasound fetal heart rate            •     Apgar score.
monitor is by far the best as the fetal heart         •     Bag and mask ventilation if needed.
is often difficult to hear with an ordinary           3. Initial newborn care
stethoscope or fetal stethoscope.
                                                      •     Prevention of hypothermia by drying the
The fetal heart rate must be counted before                 infant and providing a warm environment.
contractions (to determine the baseline               •     Routine use of vitamin K (Konakion)
heart rate) and again during and at the end                 to prevent haemorrhagic disease of the
of a contraction (to detect any early or late               newborn.
decelerations). Late decelerations are caused         •     Screen for hypoglycaemia with reagent
by fetal hypoxia and indicate fetal distress.               strips.
In a low risk labour, the fetal heart should be       •     Sample gastric aspirate at delivery for
monitored every at least every hour.                        bubbles test and Gram stain.
                                                      4. Ongoing care
 Late decelerations must be carefully listened for.
                                                      •     Prevent hypoglycaemia by early milk
                                                            feeding (or intravenous fluids if necessary).
5-36 What can be done to prevent hypoxia              •     Preventing infection by hand washing
after delivery?                                             before handling infants.
                                                      •     Use breast milk.
The most important cause of hypoxia in the            •     Use of kangaroo mother care.
newborn infant is failure to establish good
respiration after birth (neonatal asphyxia).
72       SAVING MOTHERS AND BABIES



•     Safe transfer to a regional neonatal unit if    5-41 How can bacterial infection of the
      required.                                       newborn infant be prevented?
                                                      1. Breast feeding, especially exclusive breast
    As the prevention of preterm labour is often         feeding from the time of delivery.
    not possible, every effort must be made to give   2. Wash or spray hands before handling an
    preterm infants better care.                         infant.
                                                      3. Kangaroo mother care.
                                                      4. Good cord care.
5-38 How can Kangaroo Mother Care                     5. Prophylactic eye care with chloramphenicol
prevent neonatal deaths?                                 (Chloromycetin) ointment after birth.
                                                      6. Discharge the infant home as soon as
Kangaroo Mother Care (skin-to-skin care)                 possible.
keeps the infant warm, promotes bonding
and breast feeding, reduces the risk of serious
                                                      5-42 How can the risk of mother-to-child
infection, and allows for earlier discharge. It
                                                      transmission of hiv be reduced?
is a simple, natural and cheap way of caring
for small infants. It is very effective and           1. Antiretrovirals (AZT plus nevirapine) can
significantly reduces the neonatal mortality of          reduce the risk of HIV transmission to less
small infants, especially in poorly equipped             than 5%. Use antiretroviral treatment when
facilities.                                              indicated.
                                                      2. The risk of passing on HIV after delivery
5-39 How can infection of the fetus be                   can be prevented with formula feeds and
prevented?                                               significantly lowered with exclusive breast
                                                         feeding.
1. On-site screening all pregnant women for           3. HIV negative women must be warned
   syphilis at their first antenatal visit. Usually      against the danger of HIV infection
   the syphilis rapid test or RPR card test is           during pregnancy and while they are still
   used to screen for syphilis. Treatment must           breast feeding.
   be started immediately.                            4. Elective caesarean section reduces the risk
2. All young girls must be immunised against             of HIV transmission during labour and
   rubella before they reach puberty.                    delivery. This is usually not necessary with
3. Every effort must be taken to prevent the             good antiretroviral prophylaxis.
   heterosexual spread of HIV. There is a             5. Avoid prolonged rupture of the
   particularly high risk of spread of HIV to            membranes when possible.
   the fetus if the mother becomes infected           6. Avoid unnecessary episiotomies.
   during pregnancy.
4. Aseptic technique must be used during
                                                      5-43 What can health administrators do to
   vaginal examinations.
                                                      reduce perinatal mortality?
5. Prolonged rupture of the membranes
   should be avoided if possible.                     1. Ensure accessible maternity care facilities.
                                                      2. Basic equipment and facilities must be
5-40 What can be done to prevent infection               made available.
during labour?                                        3. Adequate numbers of staff are essential.
                                                      4. Staff rotation must be stopped to build up a
1. Using an aseptic technique during vaginal             core of experienced midwives.
   examinations.                                      5. Doctors and nurses should work as a team
2. Do not perform unnecessary vaginal                    with clear management protocols.
   examination in labour.                             6. Midwives’ opinions should be respected.
3. Antiretroviral drugs for HIV positive              7. Continuing staff training is essential.
   women.
FINDING SOLUTIONS TO MATERNAL AND PERINATAL MOR TALITY          73


8. A minimal data set must be collected and        instead. The staff should have discussed the
   regular perinatal audit meetings arranged.      problem with the referral hospital.
9. A good transport and referral system must
   be set in place.                                3. Were there any administration related
                                                   factors associated with her death?
 An adequate number of well trained staff are      Yes. Transport was inadequate. The staff may
 essential to reduce both maternal and perinatal   also have been inadequately trained and there
 mortality.                                        may not have been a management protocol for
                                                   eclampsia.

                                                   4. How can early attendance for antental
CASE STUDY 1                                       care be encouraged?
                                                   Schools, community organisations, radio,
A young women presented at an antenatal
                                                   newspapers, magazines and TV should be
clinic for the first time at 36 weeks of
                                                   used to inform the general public, and young
gestation, complaining of severe headache
                                                   women especially, about the important of
for two days. She was told to wait her
                                                   antenatal care.
turn but an hour later had a generalised
convulsion. When she was found to be
hypertensive, eclampsia was diagnosed. She         5. What can be done to improve the care
was given an injection of phenobarbitone           provided at an antenatal clinic?
and an ambulance was ordered to transfer           The clinic staff must be well trained and
her to hospital. The referral hospital was not     must develop a culture of ‘patient friendly’
contacted. Unfortunately the ambulance was         care. Clear management protocols and
delayed. While waiting for the ambulance she       referral criteria are essential, and they must
had another convulsion and died.                   communicate with their referral hospital if
                                                   patients need to be referred.
1. What patient related factors are
associated with this avoidable maternal            6. How can the administration prevent
death?                                             similar maternal deaths at clinics?
The women booked very late for antenatal           Adequate staffing and facilities, good
care. If she attended antenatal care from early    communication and transport must be
in her pregnancy, she may have learned that        provided. Ideally, each community should be
severe headache was a danger sign and that         within reach of a clinic.
she should have reported immediately to the
clinic. Hypertension and proteinuria may also
have been detected at an earlier visit.            CASE STUDY 2
2. What errors did the staff make?                 In a review of potentially avoidable causes of
There were a number of health worker related       perinatal death in an urban health service, a
factors which were associated with this            case study is discussed. The woman presented
woman’s death. She should have been seen           in labour and reported poor fetal movements
immediately but her severe headache was            for the past two days. A partogram was not
not recognised as a danger sign. The correct       used as a short labour was expected. The fetal
management protocol for convulsions was            heart was recorded every 4 hours. After a
not followed and phenobarbitone was given          prolonged second stage with meconium stained
74    SAVING MOTHERS AND BABIES



liquor, a fresh stillborn infant was delivered by   4. What health worker related factors
the midwife. The doctor had not been called.        during neonatal care are associated with
                                                    perinatal death?
1. During this woman’s pregnancy were               Inadequate resuscitation, poor monitoring of
there any patient related avoidable factors         the infant, no management plan and a delay in
associated with the stillbirth?                     calling for help. Inadequate resuscitation is a
Yes. The mother should have come to the             major preventable cause of early neonatal death.
clinic when she first noticed that the fetal
movements had suddenly decreased. Failure           5. What are the three primary causes of
to report important danger signs in pregnancy       neonatal death which urgently need to be
remains a common patient related factor in          addressed in South Africa.
perinatal deaths.
                                                    Spontaneous preterm labour, intrapartum
                                                    hypoxia and infection. The case is an example
2. Should a partogram have been used to             of intrapartum hypoxia.
monitor labour?
Yes. A partogram should always be used. Not
using a partogram at all, or failing to use a       CASE STUDY 3
partogram correctly, is common health worker
related factor in potentially avoidable perinatal   After reading the summary of early neonatal
deaths. The condition of the mother and fetus,      deaths in a large teaching hospital, the doctor
as well as the progress of labour, should have      in charge of newborn care decided that
been carefully assessed at regular intervals. If    something drastic had to be done to reduce
this had been done correctly the stillbirth may     the unacceptably high early neonatal mortality
have been avoided.                                  rate. He called all the nursing and medical
                                                    staff together to discuss the problem and make
3. During the second stage of labour, what          suggestions to prevent further deaths.
were the health worker related factors
associated with the stillbirth?                     1. Can early neonatal deaths be prevented?
With meconium stained labour and a history          Yes. With simple, good management many
of poor fetal movements, the fetal heart rate       early neonatal deaths can be prevented.
should have been very closely monitored
(every half hour). In addition, the second          2. What is needed to prevent most early
stage of labour should not have been allowed        neonatal deaths?
to become prolonged. The doctor should also
have been called. Important health worker           Common causes of death and the important
related factors during labour, which are            avoidable factors need to be identified. Then a
associated with perinatal deaths, include poor      clear plan to manage these common problems
monitoring of the fetus, failure to detect fetal    must be drawn up. As these are already
distress and poor response to fetal distress.       available, all that is now required is the will to
Inadequate monitoring during labour is the          make the plan work.
commonest health worker related factor
associated with perinatal deaths.                   3. What can be done during pregnancy to
                                                    reduce the early neonatal death rate?
                                                    1. Encourage early booking and practice
                                                       good antenatal care.
                                                    2. Screen for and treat syphilis.
                                                    3. Monitor fetal growth and fetal movements.
FINDING SOLUTIONS TO MATERNAL AND PERINATAL MOR TALITY       75


4. Teach pregnant women the danger signs.         the end of contractions in order to detect late
                                                  decelerations. The fetal heart must be clearly
Good antenatal care to prevent, detect and
                                                  heard, with a Doptone if necessary.
manage problems with the fetus should be
made available to all pregnant women. It is
better and cheaper to prevent than to treat a     6. What simple steps can be done after
neonatal problem.                                 delivery to prevent infection in the
                                                  newborn infant.
4. What should be done after delivery to          1. Encourage exclusive breastfeeding.
reduce the early neonatal mortality rate?         2. Wash or spray hands before examining an
                                                     infant.
1. Diagnose and treat asphyxia.
                                                  3. Promote kangaroo mother care.
2. Keep infants warm and dry, preferably with
                                                  4. Give prophylactic cord and eye care.
   kangaroo mother care.
3. Weigh all infants to identify low birth
   weight infants who may need extra care.        7. How can the mother-to-child
4. Promote exclusive breastfeeding.               transmission of HIV be reduced?
5. Provide good basic newborn care.               1. Offer HIV screening to all pregnant women.
                                                  2. Antiretroviral drugs can halve the risk of
5. How can monitoring the fetal heart                HIV transmission to the infant.
during labour be improved?                        3. Exclusive breast or exclusive formula feed.
Staff must be taught to listen to and count the
fetal heart rate between and immediately after

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Finding solutions to prevent maternal and perinatal deaths

  • 1. 5 Finding solutions to maternal and perinatal mortality Before you begin this unit, please take the FINDING SOLUTIONS corresponding test at the end of the book to assess your knowledge of the subject matter. You should redo the test after you’ve worked through 5-1 How can you find solutions to maternal the unit, to evaluate what you have learned. and perinatal deaths? Objectives There are a number of steps which are needed: 1. Specific avoidable factors, missed When you have completed this unit you opportunities and substandard care have to be identified. should be able to: 2. You need to know where and how to look • Find solutions to the common causes of for answers to these problems. maternal and perinatal deaths. 3. Answers have to be found. • List the potentially avoidable causes of 4. Changes have to be introduced. maternal death. 5-2 What is an avoidable factor? • Take steps to prevent maternal death. • List the potentially avoidable causes of An avoidable (or modifiable) factor is something which may have prevented the perinatal death. death, e.g. a woman not immediately going to • Take steps to avoid the primary causes of a clinic or hospital when abdominal pain with perinatal death. vaginal bleeding occurs during pregnancy. • Improve the care of newborn infants. Many avoidable factors are due to missed opportunities. An avoidable factor may have prevented a death.
  • 2. FINDING SOLUTIONS TO MATERNAL AND PERINATAL MOR TALITY 65 5-3 What is a missed opportunity? Regular mortality meetings are an excellent way of identifying problems and avoidable A missed opportunity is a chance to provide factors. the correct care which was not taken. The opportunity was there to provide the correct management but the opportunity was missed, 5-6 How can avoidable factors be e.g. failing to measure the blood pressure at an classified? antenatal visit or not screening for syphilis. Avoidable factors can usually be classified into NOTE A missed opportunity is when an action or one of three groups: omission by the patient, administration or health 1. Patient related factors. worker results in an adverse outcome for the 2. Health worker related factors. mother or infant. 3. Administrative related factors. 5-4 How can you recognise substandard For example, if a fetus or newborn infant dies care? of congenital syphilis and the mother failed to attend antenatal care, then the avoidable factor Substandard care means that the care that would have been patient related. However, if the patient received fell below the standard the mother attended the antenatal clinic but that should have been offered to her. It is the health care worker failed to screen her necessary to know what correct care is before for syphilis or failed to collect the result and substandard care can be recognised. Care may treat her, then the avoidable factor would be substandard because of any of the following: have been health worker related. Finally, if 1. The patient did not go for care. the mother attended antenatal clinic and the 2. The facilities were inadequate. health worker wanted to screen her for syphilis 3. Shortage of staffing or poor staff training. but either transport or the facilities to perform 4. Staff did not provide the correct care the test were not available, then the avoidable needed. factor would have been administrative related. Substandard care often leads to avoidable Some avoidable factors are obviously the factors and missed opportunities. Therefore, cause of a maternal or perinatal death while substandard care, avoidable factors and other avoidable factors may have contributed missed opportunities are usually considered to the death. Therefore, avoidable factors can together as problems resulting in poor care. be divided into probable and possible factors. Typical examples of substandard care are not Probable avoidable factors are most important. monitoring the fetal heart during labour and Often more than one probably avoidable factor not suctioning the mouth of a meconium will be present. stained infant before delivering the shoulders. In addition, some substandard care may not be related to the death of an infant. This poor care 5-5 How are problems and avoidable can still be discussed at a perinatal mortality factors identified? meeting although it will not be included as an Answers cannot be found before the problems avoidable cause of infant death. and avoidable factors are identified. As problems (i.e. causes of maternal and perinatal 5-7 How can avoidable factors related to deaths) differ between different services, health workers be subdivided? hospitals or clinics , the particular problems 1. An honest error, e.g. overestimating the have to be identified for each service, hospital gestational age. or clinic. The avoidable factors associated with 2. An oversight, e.g. forgetting to measure the each problem may also vary between services, blood pressure. hospitals or clinics.
  • 3. 66 SAVING MOTHERS AND BABIES 3. A serious deviation from the accepted 6. Adequate public transport and ambulance practice, e.g. failing to see the patient when services. called to do so. 5-11 How can these changes be made? 5-8 Why is it important to identify the Once answers are found, there are number of specific avoidable factor? steps which can be taken to introduce changes: Only when the specific avoidable factor or 1. Notifying the health authorities. missed opportunity has been identified can 2. Altering protocols in clinics and hospitals. steps be taken to prevent similar deaths in 3. Improving the frequency and content of future. If one does not know why the care was training programmes. substandard, it would be very difficult to solve 4. Involving the community. the problem. Finding avoidable factors is an However, it is not always easy to introduce important step in improving care. the changes needed to reduce mortality. A clear idea of what changes are needed together 5-9 Where can you look for answers? with the ability to win the co-operation of the There are many sources where answers can be authorities and colleagues are essential. found once the problem has been identified. Some answers are easy to find. Unfortunately some problems still do not have easy or effective AVOIDABLE FACTORS answers, e.g. how to prevent pre-eclampsia. ASSOCIATED WITH Answers can usually be found: MATERNAL DEATHS 1. By consulting colleagues, especially those at referral hospitals. 2. In standard textbooks or journals. 5-12 Can maternal deaths be prevented? 3. In training programmes, such as the Yes. In almost half of the maternal deaths Perinatal Education Programme. there was a an avoidable factor (missed 4. By attending courses. opportunity for preventing that death or 5. In local management protocols. substandard care). Avoidable factors were 6. In provincial or national guidelines. far more common for direct causes (e.g. 7. On the internet. postpartum haemorrhage) than indirect causes (e.g. AIDS). The maternal mortality 5-10 What changes should be made to rate is still far too high in South Africa. reduce mortality rates? NOTE Information on causes of maternal death Changes may be needed in a number of and avoidable factors is taken from the Saving different areas: Mothers 2002–2004: Third report on confidential enquiries into maternal deaths in South Africa. 1. Changes in the general community, e.g. better housing, education and income. 5-13 What specific patient related avoidable 2. Changes may be needed in antenatal factors are associated with maternal death? care, e.g. better booking rates, improved screening for hypertension and proteinuria. 1. No, late or inadequate antenatal care. 3. Better patient education, e.g. the 2. Delay in seeking help during labour. importance of being aware of fetal 3. Not recognising danger signs and movements and danger signs in pregnancy. symptoms. 4. Improved facilities and staff numbers. 4. Self-induced termination of pregnancy. 5. More continuing training for health workers.
  • 4. FINDING SOLUTIONS TO MATERNAL AND PERINATAL MOR TALITY 67 5-14 What specific health worker related pregnant woman going to the clinic or hospital avoidable factors are associated with as soon as labour starts, or transport my not be maternal death? available at night. 1. Failure to follow management protocols. 2. Failure to adequately resuscitate acutely ill Every effort must be made to provide good, early women. antenatal care to all pregnant women. 3. Inadequate anaesthetic experience. 4. Poor record keeping. 5. Delay in referral to a level 1 or 2 unit. 5-17 What can be done to improve the care provided by health workers? 5-15 What specific administrative related 1. Ensure patient access to adequately staffed avoidable factors are associated with and equipped maternity services. maternal death? 2. Easily understandable management 1. Lack or delay of transport. protocols are essential. 2. Lack of intensive care facilities and theatres. 3. Simple referral guidelines are essential. 3. Lack of enough, well trained midwives and 4. A culture of ‘patient friendly’ care must be medical officers. developed in all health services. 4. Poor communication between health 5. A system of good record keeping is workers. essential. 5. Lack of management protocols. 6. Basic training must be improved and on- 6. Inadequate supply of blood. going ‘in-service’ education provided. 7. Adequately staffed facilities for termination 5-16 How can patient related factors be of pregnancy, antenatal and labour care addressed? must be made available in all districts. 8. Provide good patient transport and Every effort must be made to get women to telephone or radio communication. attend an antenatal care clinic from the time that pregnancy is confirmed. They must also be educated to recognise danger symptoms PREVENTING MATERNAL and signs and report immediately to a clinic or hospital as soon as these present: DEATHS 1. All pregnant women should be referred to an antenatal clinic as soon as their 5-18 What are the key recommendations to pregnancy is confirmed. This message prevent maternal deaths? should be made known to all general practitioners and other health care 1. Clearly understood protocols are needed to professionals. manage conditions which commonly result 2. Pregnant women should plan to be in maternal deaths. delivered by a skilled attendant and not at 2. A simple set of referral criteria is needed. home by a family member. 3. Adequate staffing and equipment norms 3. Schools, community organisations, radio, are needed and must be implemented. newspapers, magazines and TV should 4. The partogram must be used to monitor stress the importance of early antenatal care every labour. and the common danger signs in pregnancy. 5. Blood and regional anaesthesia must be available at all institutions where caesarean Patient related factors often depend on sections are performed. the family and community. For example, a husband or mother-in-law may prevent a
  • 5. 68 SAVING MOTHERS AND BABIES 6. Midwife Obstetric Clinics (nurse base 6. Combination antiretroviral treatment primary care clinics) must be established and prophylactic co-trimoxazole must in urban areas. be made available to all HIV positive 7. Termination of pregnancy services must be pregnant women who meet the clinical or expanded. immunological criteria. 8. Family planning services must be supported especially for women over 30 years or with five or more children. AVOIDABLE FACTORS 9. A national HIV/AIDS policy must be widely implemented. ASSOCIATED WITH PERINATAL DEATHS 5-19 Should every maternal death be reported? 5-21 Can perinatal deaths be prevented? Yes. The routine reporting and a confidential enquiry into maternal deaths must be Yes. In about a quarter of perinatal deaths expanded to include all maternal deaths, there was a missed opportunity for preventing especially in districts, regions and provinces that death. The commonest avoidable factors where maternal deaths are still under reported. are patient related. Unfortunately an avoidable It is important to include all maternal deaths factor often cannot be identified because of from private hospitals and the deaths that poor notes. occur at home. Only when the majority of maternal deaths are reported can a reliable The commonest avoidable factors in perinatal estimate of numbers, causes and avoidable death are patient related. factors be obtained. NOTE In the 2003-6 Saving Babies report 16% of 5-20 What national HIV/AIDS policy is avoidable factors were patient related, 15% health needed for pregnant women? worker related and 67% administrative related. 1. Guidelines on how to manage pregnant women who are HIV positive must be 5-22 What are the important patient related implemented in all districts. factors associated with perinatal death? 2. HIV counselling, testing and prophylactic The commonest patient related factors are: antiretrovirals must urgently be made available at all antenatal clinics in order 1. No attendance, late attendance or irregular to reduce the risk of mother-to-child attendance for antenatal care. transmission of HIV. 2. Inadequate response to decreased fetal 3. Contraceptive advice and the option of movements. terminating the pregnancy should be 3. Inadequate response to rupture of the available. membranes. 4. All clinics and hospitals have an obligation 4. Inadequate response to antepartum to their staff to ensure that the training haemorrhage. and equipment is available to prevent HIV 5. Delay in seeking medical attention in transmission to their staff (e.g. gloves, labour. plastic aprons, glasses or masks, blunt- Failing to book early and then regularly attend tipped needles, skin clips and sharps antenatal care is the commonest patient containers). related factor associate with perinatal death. 5. CD4 screening must be done on all Little understanding of the importance of pregnant women who are HIV positive antenatal care, long distances to the clinic
  • 6. FINDING SOLUTIONS TO MATERNAL AND PERINATAL MOR TALITY 69 and inadequate public transport all play 5. No response to hypertension. an important role in poor attendance for 6. Multiple pregnancy not diagnosed. antenatal care. 7. No response to syphilis serology. 8. No response to glycosuria. 9. No response to post term pregnancy. Inadequate antenatal care is the commonest patient related factor associated with perinatal No response by health workers to antenatal death. warning signs is a common avoidable factor associated with perinatal death. Because of poor antenatal clinic attendance, complications of pregnancy such as hypertension, decreased fetal growth and 5-26 What are the important health worker syphilis are not identified and managed. related factors during labour that are associated with perinatal death? 5-23 What are the important administrative 1. Partogram not used. related factors associated with perinatal 2. Fetus not adequately monitored. death? 3. Signs of fetal distress not interpreted 1. Transport delays in getting the patient correctly or ignored. between health institutions, e.g. getting a 4. No response to poor progress of labour. patient from a clinic to a hospital. 5. Prolonged second stage not managed 2. Lack of adequate screening for syphilis. correctly. 3. Too few staff or inadequately trained staff. 6. Delay in calling a doctor or referring the 4. Inadequate facilities, especially theatre and patient. neonatal care facilities. Inadequate fetal monitoring is the commonest Inadequate transport to hospital is the commonest health worker related factor associated with administrative related factor associated with perinatal death during labour. perinatal death. 5-27 What are the important health worker related factors during neonatal care that 5-24 When are health worker related are associated with perinatal death? factors associated with perinatal death? 1. Inadequate resuscitation. Health worker related factors may be divided 2. Inadequate monitoring or management into: plan. 1. Antepartum factors (during pregnancy). 3. Delay in calling for assistance or 2. Intrapartum factors (during labour). transferring the infant to a level 2 or 3 unit. 3. Neonatal care factors (care of the infant after delivery). Inadequate resuscitation of the newborn is an 5-25 What are the important health worker important avoidable cause of perinatal death. related factors during antenatal care that are associated with perinatal death? 5-28 Which primary causes of neonatal 1. No response to a poor past obstetric history. mortality urgently need solutions? 2. Over or underestimating fetal size. The three main primary causes of neonatal 3. No response to poor uterine growth. mortality are: 4. No response to poor fetal movement.
  • 7. 70 SAVING MOTHERS AND BABIES 1. Spontaneous preterm delivery. 5-31 What should be done to reduce the 2. Intrapartum hypoxia. perinatal mortality rate during labour? 3. Infection. 1. Correct use of the partogram in all labours. 2. Correct method of monitoring the fetal heart rate. PREVENTING PERINATAL 3. Clear protocols of management. MORTALITY 4. Indications for referral. 5. Adequate equipment that is maintained in good working order. 5-29 Can perinatal mortality be prevented? Yes. Many perinatal deaths can be prevented: 5-32 What should be done to reduce the perinatal mortality rate after delivery: 1. We know that the perinatal mortality rate in South Africa is far too high. 1. Early diagnosis of birth asphyxia (not 2. We know what the major causes are. breathing well after delivery). 3. We have identified many of the avoidable 2. Knowledge, skills and equipment for good factors. resuscitation. 4. We know how to manage most of these 3. Keep infants dry and warm. problems. 4. Kangaroo mother care. 5. Weigh all infants to identify low birth All that we now need is a clear plan of action weight infants. and the will to make the plan work. 6. Good basic newborn care. 7. Breastfeeding (preferably exclusive With simple, good management many of the breastfeeding). perinatal deaths can be prevented. It is essential that the facilities, necessary equipment, management protocols and adequate numbers of well trained health 5-30 What should be done to reduce the workers are available at each clinic and hospital. perinatal mortality rate during pregnancy? It is every woman’s right to have a safe delivery. There are many avoidable factors which can be addressed to reduce the perinatal mortality. 5-33 Why do some infants die of The most important are: intrapartum hypoxia? 1. Early booking, preferably at the time that Intrapartum hypoxia means that the fetus did pregnancy is diagnosed. not receive enough oxygen before delivery 2. On-site screening for syphilis and early (usually during labour). The main reasons for treatment. fetal hypoxia are: 3. Clear protocols for good routine antenatal 1. Placental abruption. care and indications for referral. 2. Prolonged or obstructed labour. 4. Fetal growth monitoring using symphysis- 3. Fetal growth restriction or wasting (poor fundal height measurements correctly. fetal growth or weight loss). 5. Teaching mothers to monitor fetal 4. Maternal disease, e.g. pre-eclampsia, movements. diabetes and syphilis. 6. Teaching mothers the danger signs of 5. Prolapsed umbilical cord. complications. The infant may also developed hypoxia after delivery if they breathe poorly and are not well resuscitated.
  • 8. FINDING SOLUTIONS TO MATERNAL AND PERINATAL MOR TALITY 71 5-34 What can be done to reduce the risk of This results in a 1 minute Apgar score of fetal hypoxia? less than 7. It is essential to detect neonatal asphyxia early and to resuscitate the infant Every effort should be made to prevent fetal well. Everyone delivering a newborn infant hypoxia, and detect fetal distress as soon must be able to provide basic resuscitation, as it develops. Careful monitoring of the especially bag and mask ventilation. Oxygen is fetal condition and the progress of labour not necessary for resuscitation. is essential. The partogram must be used correctly to detect poor progress of labour. Fetal hypoxia presents with the signs of fetal The most important step in newborn distress, i.e. meconium stained liquor and late resuscitation is bag and mask ventilation. fetal heart rate decelerations (and poor beat- to-beat variability on the cardiotocogram). 5-37 What can be done to decrease the mortality of preterm infants? Correct use of the partogram with careful fetal While it is difficult to prevent preterm delivery, monitoring is essential. a lot can be done to prevent the early neonatal death of preterm infants: 5-35 How can monitoring of the fetal heart 1. Anticipation rate during labour be improved? • Giving betamethasone to the mother for It is impractical to have a cardiotochograph 48 hours before delivery to promote lung (CTG) recorder in every labour ward. maturity. Therefore, the fetal heart must be • Deliver the mother in a level 2 or 3 hospital. monitored with an ordinary stethoscope, 2. Early recognition of neonatal asphyxia a fetal stethoscope or a hand held Doppler and good resuscitation ultrasound fetal heart rate monitor (a ‘Doptone’). An ultrasound fetal heart rate • Apgar score. monitor is by far the best as the fetal heart • Bag and mask ventilation if needed. is often difficult to hear with an ordinary 3. Initial newborn care stethoscope or fetal stethoscope. • Prevention of hypothermia by drying the The fetal heart rate must be counted before infant and providing a warm environment. contractions (to determine the baseline • Routine use of vitamin K (Konakion) heart rate) and again during and at the end to prevent haemorrhagic disease of the of a contraction (to detect any early or late newborn. decelerations). Late decelerations are caused • Screen for hypoglycaemia with reagent by fetal hypoxia and indicate fetal distress. strips. In a low risk labour, the fetal heart should be • Sample gastric aspirate at delivery for monitored every at least every hour. bubbles test and Gram stain. 4. Ongoing care Late decelerations must be carefully listened for. • Prevent hypoglycaemia by early milk feeding (or intravenous fluids if necessary). 5-36 What can be done to prevent hypoxia • Preventing infection by hand washing after delivery? before handling infants. • Use breast milk. The most important cause of hypoxia in the • Use of kangaroo mother care. newborn infant is failure to establish good respiration after birth (neonatal asphyxia).
  • 9. 72 SAVING MOTHERS AND BABIES • Safe transfer to a regional neonatal unit if 5-41 How can bacterial infection of the required. newborn infant be prevented? 1. Breast feeding, especially exclusive breast As the prevention of preterm labour is often feeding from the time of delivery. not possible, every effort must be made to give 2. Wash or spray hands before handling an preterm infants better care. infant. 3. Kangaroo mother care. 4. Good cord care. 5-38 How can Kangaroo Mother Care 5. Prophylactic eye care with chloramphenicol prevent neonatal deaths? (Chloromycetin) ointment after birth. 6. Discharge the infant home as soon as Kangaroo Mother Care (skin-to-skin care) possible. keeps the infant warm, promotes bonding and breast feeding, reduces the risk of serious 5-42 How can the risk of mother-to-child infection, and allows for earlier discharge. It transmission of hiv be reduced? is a simple, natural and cheap way of caring for small infants. It is very effective and 1. Antiretrovirals (AZT plus nevirapine) can significantly reduces the neonatal mortality of reduce the risk of HIV transmission to less small infants, especially in poorly equipped than 5%. Use antiretroviral treatment when facilities. indicated. 2. The risk of passing on HIV after delivery 5-39 How can infection of the fetus be can be prevented with formula feeds and prevented? significantly lowered with exclusive breast feeding. 1. On-site screening all pregnant women for 3. HIV negative women must be warned syphilis at their first antenatal visit. Usually against the danger of HIV infection the syphilis rapid test or RPR card test is during pregnancy and while they are still used to screen for syphilis. Treatment must breast feeding. be started immediately. 4. Elective caesarean section reduces the risk 2. All young girls must be immunised against of HIV transmission during labour and rubella before they reach puberty. delivery. This is usually not necessary with 3. Every effort must be taken to prevent the good antiretroviral prophylaxis. heterosexual spread of HIV. There is a 5. Avoid prolonged rupture of the particularly high risk of spread of HIV to membranes when possible. the fetus if the mother becomes infected 6. Avoid unnecessary episiotomies. during pregnancy. 4. Aseptic technique must be used during 5-43 What can health administrators do to vaginal examinations. reduce perinatal mortality? 5. Prolonged rupture of the membranes should be avoided if possible. 1. Ensure accessible maternity care facilities. 2. Basic equipment and facilities must be 5-40 What can be done to prevent infection made available. during labour? 3. Adequate numbers of staff are essential. 4. Staff rotation must be stopped to build up a 1. Using an aseptic technique during vaginal core of experienced midwives. examinations. 5. Doctors and nurses should work as a team 2. Do not perform unnecessary vaginal with clear management protocols. examination in labour. 6. Midwives’ opinions should be respected. 3. Antiretroviral drugs for HIV positive 7. Continuing staff training is essential. women.
  • 10. FINDING SOLUTIONS TO MATERNAL AND PERINATAL MOR TALITY 73 8. A minimal data set must be collected and instead. The staff should have discussed the regular perinatal audit meetings arranged. problem with the referral hospital. 9. A good transport and referral system must be set in place. 3. Were there any administration related factors associated with her death? An adequate number of well trained staff are Yes. Transport was inadequate. The staff may essential to reduce both maternal and perinatal also have been inadequately trained and there mortality. may not have been a management protocol for eclampsia. 4. How can early attendance for antental CASE STUDY 1 care be encouraged? Schools, community organisations, radio, A young women presented at an antenatal newspapers, magazines and TV should be clinic for the first time at 36 weeks of used to inform the general public, and young gestation, complaining of severe headache women especially, about the important of for two days. She was told to wait her antenatal care. turn but an hour later had a generalised convulsion. When she was found to be hypertensive, eclampsia was diagnosed. She 5. What can be done to improve the care was given an injection of phenobarbitone provided at an antenatal clinic? and an ambulance was ordered to transfer The clinic staff must be well trained and her to hospital. The referral hospital was not must develop a culture of ‘patient friendly’ contacted. Unfortunately the ambulance was care. Clear management protocols and delayed. While waiting for the ambulance she referral criteria are essential, and they must had another convulsion and died. communicate with their referral hospital if patients need to be referred. 1. What patient related factors are associated with this avoidable maternal 6. How can the administration prevent death? similar maternal deaths at clinics? The women booked very late for antenatal Adequate staffing and facilities, good care. If she attended antenatal care from early communication and transport must be in her pregnancy, she may have learned that provided. Ideally, each community should be severe headache was a danger sign and that within reach of a clinic. she should have reported immediately to the clinic. Hypertension and proteinuria may also have been detected at an earlier visit. CASE STUDY 2 2. What errors did the staff make? In a review of potentially avoidable causes of There were a number of health worker related perinatal death in an urban health service, a factors which were associated with this case study is discussed. The woman presented woman’s death. She should have been seen in labour and reported poor fetal movements immediately but her severe headache was for the past two days. A partogram was not not recognised as a danger sign. The correct used as a short labour was expected. The fetal management protocol for convulsions was heart was recorded every 4 hours. After a not followed and phenobarbitone was given prolonged second stage with meconium stained
  • 11. 74 SAVING MOTHERS AND BABIES liquor, a fresh stillborn infant was delivered by 4. What health worker related factors the midwife. The doctor had not been called. during neonatal care are associated with perinatal death? 1. During this woman’s pregnancy were Inadequate resuscitation, poor monitoring of there any patient related avoidable factors the infant, no management plan and a delay in associated with the stillbirth? calling for help. Inadequate resuscitation is a Yes. The mother should have come to the major preventable cause of early neonatal death. clinic when she first noticed that the fetal movements had suddenly decreased. Failure 5. What are the three primary causes of to report important danger signs in pregnancy neonatal death which urgently need to be remains a common patient related factor in addressed in South Africa. perinatal deaths. Spontaneous preterm labour, intrapartum hypoxia and infection. The case is an example 2. Should a partogram have been used to of intrapartum hypoxia. monitor labour? Yes. A partogram should always be used. Not using a partogram at all, or failing to use a CASE STUDY 3 partogram correctly, is common health worker related factor in potentially avoidable perinatal After reading the summary of early neonatal deaths. The condition of the mother and fetus, deaths in a large teaching hospital, the doctor as well as the progress of labour, should have in charge of newborn care decided that been carefully assessed at regular intervals. If something drastic had to be done to reduce this had been done correctly the stillbirth may the unacceptably high early neonatal mortality have been avoided. rate. He called all the nursing and medical staff together to discuss the problem and make 3. During the second stage of labour, what suggestions to prevent further deaths. were the health worker related factors associated with the stillbirth? 1. Can early neonatal deaths be prevented? With meconium stained labour and a history Yes. With simple, good management many of poor fetal movements, the fetal heart rate early neonatal deaths can be prevented. should have been very closely monitored (every half hour). In addition, the second 2. What is needed to prevent most early stage of labour should not have been allowed neonatal deaths? to become prolonged. The doctor should also have been called. Important health worker Common causes of death and the important related factors during labour, which are avoidable factors need to be identified. Then a associated with perinatal deaths, include poor clear plan to manage these common problems monitoring of the fetus, failure to detect fetal must be drawn up. As these are already distress and poor response to fetal distress. available, all that is now required is the will to Inadequate monitoring during labour is the make the plan work. commonest health worker related factor associated with perinatal deaths. 3. What can be done during pregnancy to reduce the early neonatal death rate? 1. Encourage early booking and practice good antenatal care. 2. Screen for and treat syphilis. 3. Monitor fetal growth and fetal movements.
  • 12. FINDING SOLUTIONS TO MATERNAL AND PERINATAL MOR TALITY 75 4. Teach pregnant women the danger signs. the end of contractions in order to detect late decelerations. The fetal heart must be clearly Good antenatal care to prevent, detect and heard, with a Doptone if necessary. manage problems with the fetus should be made available to all pregnant women. It is better and cheaper to prevent than to treat a 6. What simple steps can be done after neonatal problem. delivery to prevent infection in the newborn infant. 4. What should be done after delivery to 1. Encourage exclusive breastfeeding. reduce the early neonatal mortality rate? 2. Wash or spray hands before examining an infant. 1. Diagnose and treat asphyxia. 3. Promote kangaroo mother care. 2. Keep infants warm and dry, preferably with 4. Give prophylactic cord and eye care. kangaroo mother care. 3. Weigh all infants to identify low birth weight infants who may need extra care. 7. How can the mother-to-child 4. Promote exclusive breastfeeding. transmission of HIV be reduced? 5. Provide good basic newborn care. 1. Offer HIV screening to all pregnant women. 2. Antiretroviral drugs can halve the risk of 5. How can monitoring the fetal heart HIV transmission to the infant. during labour be improved? 3. Exclusive breast or exclusive formula feed. Staff must be taught to listen to and count the fetal heart rate between and immediately after