3. About us
ttopstart is a consultancy firm for business generation in the life
sciences, healthcare and medical technology. We deliver the intelligence
required for strategic decisions, develop strong business plans and realise
business and project financing.
ttopstart is passionate to turn groundbreaking innovations into profitable
products and services.
• INTELLIGENCE • TRUST • QUALITY
3
5. SECTORS
Life Sciences Medical Technology
Novel medication for cancer patients, reliable diagnoses Improved MRI scan results, 3D simulation of the human
based on gene profiling, enzymes as catalyst in chemistry: body, telemonitoring of hearth patients: high-tech research
innovations in the Life sciences bring valuable technolo- delivers exiting new technologies with a large impact
gies to society. However, successful commercialisation on existing medical practice. In contrast the market is
of innovations is a major challenge due to hard to raise highly competitive, products have a short life cycle and the
financing, long development trajectories, strict regula- transparency in the application areas is not eminent. It is
tions and difficult reimbursement models. We work from our commitment to identify the challenges that your tech-
the premise that science has to be combined with market nology will face and anticipate accordingly.
intelligence to optimally leverage valuable innovations in
this challenging sector.
Healthcare
Increasing market force, pressure on reimbursement, an
aging population, demanding patients and automation
threaten the quality of healthcare. Innovations can con-
tribute in many ways to maintain and improve this quality.
In order to successfully introduce and finance healthcare
innovations ttopstart supports healthcare organizations
during the entire innovation process. Doing so, new prod-
ucts, services and processes are successfully implemented
in daily practice.
5
6. BUSINESS DEVELOPMENT
The healthcare and life sciences market is highly Business Plan
competitive and promising research does not guarantee ttopstart offers the service to set up a sound and per-
successful commercialisation. Under influence of defiant suasive business plan for new activities. It is our task to
conditions your business should be cleverly shaped. visualise your plans, deliver key market insights and assess
ttopstart is specialised in analysing the options for com- commercial and financial feasibility. Your business plan
mercial activity and in calculating feasibility of different with ttopstart label will allow you to objectively review
concepts. Based on such crucial information we offer the concept and to convince investors to provide financial
support in setting up a strong business plan. With our backup.
support, a number of clients has been able to determine
the best route of commercialisation and to convince stake- Business Case
holders and investors of their business concept. By sup- In early stages of commercialisation a business case offers
porting business development activities, ttopstart is able rapid insight in the added value of innovations. Such docu-
to offer entrepreneurs and organizations the extra tools ment is helpful to inform third parties on your plans and
to manage a healthy business. allows you to quickly oversee commercial routes. This gives
you the essential basis for further development. ttopstart
is dedicated to support you in formulating a well-struc-
tured business case, built on relevant market information.
Project Management
During innovation processes it is crucial to initiate and
continue management activities in addition to product
development. We are able to support you in carrying
part of these responsibilities. Please contact us for more
information.
6
7. “Thanks to ttopstart, DCPrime has
access to market insights and other
intelligence needed for preparation
of its VC and company presentations.”
Prof. Dr. A.M. (Ada) Kruisbeek, CEO/CSO DCPrime B.V.
8.
9. INTELLIGENCE
Reliable market information is of key importance in set- Market research
ting up business activities. Strategic decisions have to In landscaping your market, we use our extensive network
be based on insights in market size, segmentation, the and consult direct stakeholders and experts. Furthermore,
competitive landscape, the latest state of art and reim- we dig into proprietary databases and analyse competi-
bursement options. Besides, the IP landscape influences tive behavior. We present these data in a transparent and
the potential of winning a strong market position. For this structured report and talk you through the most impor-
reason it is crucial to identify key opportunities and to tant conclusions. This will not only give you an apprehen-
determine the market impact of your innovation. sion of market statistics and trends, but also provides you
By consulting key opinion leaders and market players we with essential information on potential customers and
are able to map niche markets, identify critical unmet market opportunities.
medical needs and recognise interesting business oppor-
tunities. Based on the objective market view generated by IP Landscaping
ttopstart, you will be able to comprehend commercial and By mapping the IP landscape of your innovation we offer
technological feasibility. you insight into potential prior art and into competitive
activities. We are skilled in patent database searches and
deliver a lucid IP overview.
“For the VIRGO consortium, we are continuously looking for new opportunities for which
a business plan or market analysis is essential. ttopstart has gained our trust by delivering
high-quality information for decision making.”
Prof.Dr. E.H.J.H.M (Eric) Claassen, Valorisation Manager VIRGO Consortium and CEO of Vironovative BV
9
10. FINANCING
For every business activity, financing is essential. ttopstart Subsidies
supports by mapping the financing opportunities and The ttopstart team has a background in both life sciences/
actively contributes in their raising. It is our expertise to healthcare and business and is therefore able to rapidly
support the financing of the following activities: translate scientific concepts into strong propositions. We
are specialised in translational and commercially targeted
• Translational research subsidies.
• Commercialisation or valorisation of research
• Start an innovative company Subsidy scan
• Upscaling and internationalisation of commercial We can provide you with a complete and tailored overview
activities of subsidies and other financial means for which your
• Targeting new markets company or project is eligible.
• Starting innovative healthcare concepts
• Strengthening of your proposition towards industry Private capital
Venture capital, bank loans and innovation credit: ttopstart
For this, we use a wide variety of financial resources, provides optimal advice to maximize your finance possi-
including national and international subsidies, patient bilities.
societies and funds, bank loans, innovation credit, tax
incentives and risk capital.
10
11. “The application for subsidies and grants is extraordinary
complex. ttopstart offered us the most promising opportu-
nities and a realistic outlook on the chance for success. It is
pleasant that they support you during the whole process.
So far we have received all the grants we applied for thanks
to the support of ttopstart.”
Dr. S.A. (Servaas) Morré, CSO Microbiome Ltd.
12.
13. CLIENT PROFILES
The TU/e Innovation Lab in Eindhoven fulfils an active and Steef Blok: “For us, ttopstart delivers capacity and profes-
supportive role in relation to knowledge valorisation and sionalism. They have the brains to deliver high quality
innovation. They encourage entrepreneurship by identifying, products that make us able to assist promising research
supporting and providing guidance for potential high-tech even better. Our projects are highly divers. The flexibility
startups and spin-off companies originating at the TU Eind- of ttopstart makes it possible to join forces on a variety of
hoven. For innovative research in Eindhoven the assistance projects.”
of the Innovation Lab is probably the most familiar first step
towards commercial success.
The Innovation Lab works together with ttopstart on several
projects to offer promising researchers the tools they need for
optimal valorisation. The role of ttopstart in assisting these
projects is diverse. Depending on the needs of the clients, the
Innovation Lab asks ttopstart to take care of either a business
plan; to carry out market research or to assist in acquiring
public and private capital for a project.
As a team the TU/e Innovation Lab and ttopstart were able
to assist the valorisation of promising research projects in
medical technology and healthcare. The trustworthy relation
has resulted in the successful progress of cutting edge tech-
nology towards society and industry.
13
14. Microbiome Ltd. is a molecular diagnostics company in the Because setting up a subsidy application is a time consum-
field of infectious diseases. As a spin-off from the VU Univer- ing task that requires full attention, ttopstart took care of the
sity medical center in Amsterdam, Microbiome is active in the complete process. To make the proposition as persuasive and
discovery, manufacturing and marketing of microbiological lucid as possible multiple experts within the field and key
techniques, tools, systems and characterisations. In 2008 the decision makers where consulted.
company received the Amsterdam Innovation Award for the
groundbreaking research concerning Chlamydia testing and Microbiome successfully applied for a EuroTransBio grant of
in 2011 they were nominated for the FD-Gazellen award 660.000 EUR for the development of the diagnostic test. The
grant enables the company to further develop the diagnostic
One of the R&D programs of Microbiome is the development test.
of a certified host genetic based diagnostic test to assess
Chlamydia trachomatis (CT) and other Sexually Transmitted Dr. Servaas Morré: “The application for subsidies and
Diseases (STD) associated tubal damage in subfertile women grants is extraordinary complex. ttopstart offered us the
to triage subfertile better for laparoscopy as compared to CT most promising opportunities and a realistic outlook on
serology only. the chance for success. It is pleasant that they support you
during the whole process. So far we have received all the
To realise sufficient funding for R&D, Microbiome works grants we applied for thanks to the support of ttopstart.”
together with ttopstart. In a close cooperation ttopstart Patrick de Boer MSc: “Microbiome has several promising
investigated the possibilities for Microbiome to receive R&D projects that are close to market. Therefore, we sup-
funding for the development of the genetic test. After select- ported Microbiome in attracting funding specifically for
ing the most promising funding possibilities, it was decided SMEs. With these proceeds, Microbiome is able to validate,
to apply for a European and National subsidy program. certify and market their diagnostic test”.
14
