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Design of Experiments
Dr.P.B.Bharate
Head, Department of Statistics
Vice principal, Pratap College,Amalner
Outline of discussion
•
•
•
•
•
•
•

Introduction
Experiment
Example
Models
Strategy of experimentation
Basic principles of design of experiments
Guidelines for the design of experiments
Introduction
System

Process

A system is a set of interacting or
interdependent components
forming an integrated whole.
Ex
Banking System,
Reservation system.
Social system

A Sequence of interdependent and
linked procedures which, at
every stage, consume one or
more resources (employee time,
energy, machines, money) to
convert inputs
(data, material, parts, etc.)
into outputs.
Ex. Chemical process.
Experiment
• Observing a system or process helps us to understand how system and
process works.
• To understand what happens to a process when we change certain factors
, we need to do more than observation.
• To really understand cause and effect relationship in systems we must
deliberately change the input variables to the system and observe the
output. i.e. we need to conduct experiment
• Observations on a system can lead to theories but experiments are
required to prove the theories.
• Investigators perform experiments in all fields of inquiry. Each
experimental run is a test.
• Experiment is a test or series of runs in which purposeful changes are
made to the input variables of a process or system and output response
is observed to identify the reasons for changes on out put response.
Objectives of Experiments
• Identify the input variables responsible for the
observed changes in the response variable
• To develop a model relating the response
variable with input variables.
• To use this model for process or system
improvement or other decision making.
• Experimentation plays important role in
science and engineering.
Manufacturing a car
• Productivity= Annual Revenue/ Annual cost
• Factors that affect the demand of car as follows
•
•
•
•
•
•
•
•

Mileage of car
Convenience of driving
Aesthetic of the car
Selling price of the car
Size of the population
Income level of people
Number of competing brands
Location of consumers

• The objective of company is to identify the optimum level
of production of car so as to increase the productivity
Example
• Comparison of two hardening processes i)oil
quenching and ii) salt water quenching on an
aluminum alloy
• Number of specimens or test coupons are
subjected to two media and hardness is
measured.
• Objective is to decide the best quenching
medium.
Questions about the Experiment
1. Are these two solutions the only quenching media of
interest?
2. Are there any other factors that might affect hardness that
should be investigated or controlled in this
experiment(such as the temperature)?
3. How many coupons of alloy should be tested in each
quenching solution?
4. How should the coupons be assigned to the quenching
solution and in what order data should be collected?
5. What method of data analysis should be used?
6. What difference in average observed hardness between the
two quenching solutions will be considered important?
Models
•
•
•
•
•
•

Mechanistic models
Deductive inference
From general to particular
Follow directly from the
physical mechanism
Example
Oham’s law E=IR
Mathematical model

Empirical models
• Inductive inference
• From particular to general
• Requires experimentation
• Statistical model
• We are concerned with
the turning the results of
experiments into
empirical models
Process or system
A process or system can
be represented by the
diagram
Inputs

Controlling
factors

Process

Un controling factors

outputs
Strategy of Experimentation
• The general approach of planning and conducting the experiment is called
the strategy of experimentation. Let us consider example of preparation of
curd from milk. Some of the factors that influence the preparation of curd
are as follows;
1. The temperature of the milk
2. Quantity of curd culture added to milk
3. PH value of the curd
4. Fat of milk
5. Pot used for curd
6. Room temperature
7. Seasons winter , summer , monsoon
8. Timing of the day morning , evening
9. The list can be extended.
Strategy of Experimentation
Best guess approach
Select an arbitrary combination of
factors and test it.
No guarantee of best solution

One factor at a time
approach(OFAT)
Varying each factor keeping other
factors constant.
It fails to consider any interaction

Both approaches have drawbacks. Factorial design can give better solution in
which we can test both the significance of main effects and interactions also.
Basic principles of design of
experiments
• The statistical design of experiments refers to the process of planning the
experiments so that appropriate data will be collected and analyzed by
statistical methods, resulting in valid and objective conclusions.
• There are two aspects to any experimental problem i) design of the
experiment and ii) statistical analysis of the data.
• There are three basic principles of design of experiments
i) Randomisation ii) replication iii) blocking or local control
Randomization
• Allocation of the experimental material and the order of the runs of the
experiment performed are randomly determined.
• Statistical methods require that observations (or Errors) be independently
distributed random variables. Randomization make this assumption valid.
• Randomization average out effects of extraneous factors
• Randomization can be done by computer programs or random number
tables
Replication
• Replication means independent repeat run of each factor combination.
• Experimenter can obtain the estimate of experimental error . This
estimate of error is the basic unit of measurement for determining
whether observed differences in the data are really statistically significant.
• If sample mean is used to estimate the true mean, then
• variance of sample mean=(variance of the observations)/ no. of
replications

• Increase in replications would give better estimates of mean.
Blocking
• It helps in improving the precision of the experiment
• It is used to reduce or eliminate the variability transmitted from
nuisance factors– factors that may influence the response variable
but in which we are not interested.
• Blocking means putting similar experimental material in one block.
And applying treatments in each block.
• Two batches of raw material for hardness testing experiment.
Guidelines for Designing an
Experiments
1.

Recognition of and statement of the problem

2.

Selection of the response variable

3.

Choice of factors, levels and ranges

4.

Choice of experimental design

5.

Performing the experiment

6.

Statistical analysis of the data

7.

Conclusions and recommendations

The first three points are related to pre experimental planning
Guidelines for Designing an
Experiment
1. Recognition of and statement of the problem
It is necessary to develop all ideas about the objectives of the experiment .
Team approach is useful.
Some of the reasons for running an experiment are
a)Factor screening- To find most influential factors having impact on
response variable.
b)Optimization- To find settings or levels of the important factors that
result in desirable values of response variable
c)Confirmation- To verify some theory or past experience. Testing
effectiveness of new substitute material
d) Discovery To find new material
e) RobustnessTo find the conditions under which response variable
seriously degrade
Guidelines for Designing an
Experiment
2. Selection of the response variable

It should give required information. The measurement system
capability is important.
3. Choice of factors, levels and ranges
The important factors having most influence are called design factors
or nuisance factors. These are classified as controllable,
uncontrollable and noise factors . The levels of controllable factor
are set by experimenter. It is important to minimize the variability
transmitted by noise factors .
Cause –effect diagram , Fishbone diagram, process knowledge will be
helpful in deciding levels.
Guidelines for Designing an
Experiment
4. Choice of experimental design

It depends on the previous steps .There standard designs
available. One can choose among them that best suits our
experiment. Software are also available for deciding the
design to be used. Model is also determined. it is the
empirical relation between factors and response variable
5.Performing the experiment.
Take utmost care to execute experiment as per plan. Any
mistake will lead to increase in error.
Guidelines for Designing an
Experiment
6.Statistical analysis of the data

It assures that the Conclusions are objective.
Use graphical methods and Empirical model
7. Conclusions and recommendations

Draw practical conclusions and recommend the action.
Experimentation is a iterative procedure.
Conduct series of small experiments instead of comprehensive experiment
Best luck for better experimentation

Thank you

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Planning of experiment in industrial research

  • 1. Design of Experiments Dr.P.B.Bharate Head, Department of Statistics Vice principal, Pratap College,Amalner
  • 2. Outline of discussion • • • • • • • Introduction Experiment Example Models Strategy of experimentation Basic principles of design of experiments Guidelines for the design of experiments
  • 3. Introduction System Process A system is a set of interacting or interdependent components forming an integrated whole. Ex Banking System, Reservation system. Social system A Sequence of interdependent and linked procedures which, at every stage, consume one or more resources (employee time, energy, machines, money) to convert inputs (data, material, parts, etc.) into outputs. Ex. Chemical process.
  • 4. Experiment • Observing a system or process helps us to understand how system and process works. • To understand what happens to a process when we change certain factors , we need to do more than observation. • To really understand cause and effect relationship in systems we must deliberately change the input variables to the system and observe the output. i.e. we need to conduct experiment • Observations on a system can lead to theories but experiments are required to prove the theories. • Investigators perform experiments in all fields of inquiry. Each experimental run is a test. • Experiment is a test or series of runs in which purposeful changes are made to the input variables of a process or system and output response is observed to identify the reasons for changes on out put response.
  • 5. Objectives of Experiments • Identify the input variables responsible for the observed changes in the response variable • To develop a model relating the response variable with input variables. • To use this model for process or system improvement or other decision making. • Experimentation plays important role in science and engineering.
  • 6. Manufacturing a car • Productivity= Annual Revenue/ Annual cost • Factors that affect the demand of car as follows • • • • • • • • Mileage of car Convenience of driving Aesthetic of the car Selling price of the car Size of the population Income level of people Number of competing brands Location of consumers • The objective of company is to identify the optimum level of production of car so as to increase the productivity
  • 7. Example • Comparison of two hardening processes i)oil quenching and ii) salt water quenching on an aluminum alloy • Number of specimens or test coupons are subjected to two media and hardness is measured. • Objective is to decide the best quenching medium.
  • 8. Questions about the Experiment 1. Are these two solutions the only quenching media of interest? 2. Are there any other factors that might affect hardness that should be investigated or controlled in this experiment(such as the temperature)? 3. How many coupons of alloy should be tested in each quenching solution? 4. How should the coupons be assigned to the quenching solution and in what order data should be collected? 5. What method of data analysis should be used? 6. What difference in average observed hardness between the two quenching solutions will be considered important?
  • 9. Models • • • • • • Mechanistic models Deductive inference From general to particular Follow directly from the physical mechanism Example Oham’s law E=IR Mathematical model Empirical models • Inductive inference • From particular to general • Requires experimentation • Statistical model • We are concerned with the turning the results of experiments into empirical models
  • 10. Process or system A process or system can be represented by the diagram Inputs Controlling factors Process Un controling factors outputs
  • 11. Strategy of Experimentation • The general approach of planning and conducting the experiment is called the strategy of experimentation. Let us consider example of preparation of curd from milk. Some of the factors that influence the preparation of curd are as follows; 1. The temperature of the milk 2. Quantity of curd culture added to milk 3. PH value of the curd 4. Fat of milk 5. Pot used for curd 6. Room temperature 7. Seasons winter , summer , monsoon 8. Timing of the day morning , evening 9. The list can be extended.
  • 12. Strategy of Experimentation Best guess approach Select an arbitrary combination of factors and test it. No guarantee of best solution One factor at a time approach(OFAT) Varying each factor keeping other factors constant. It fails to consider any interaction Both approaches have drawbacks. Factorial design can give better solution in which we can test both the significance of main effects and interactions also.
  • 13. Basic principles of design of experiments • The statistical design of experiments refers to the process of planning the experiments so that appropriate data will be collected and analyzed by statistical methods, resulting in valid and objective conclusions. • There are two aspects to any experimental problem i) design of the experiment and ii) statistical analysis of the data. • There are three basic principles of design of experiments i) Randomisation ii) replication iii) blocking or local control
  • 14. Randomization • Allocation of the experimental material and the order of the runs of the experiment performed are randomly determined. • Statistical methods require that observations (or Errors) be independently distributed random variables. Randomization make this assumption valid. • Randomization average out effects of extraneous factors • Randomization can be done by computer programs or random number tables
  • 15. Replication • Replication means independent repeat run of each factor combination. • Experimenter can obtain the estimate of experimental error . This estimate of error is the basic unit of measurement for determining whether observed differences in the data are really statistically significant. • If sample mean is used to estimate the true mean, then • variance of sample mean=(variance of the observations)/ no. of replications • Increase in replications would give better estimates of mean.
  • 16. Blocking • It helps in improving the precision of the experiment • It is used to reduce or eliminate the variability transmitted from nuisance factors– factors that may influence the response variable but in which we are not interested. • Blocking means putting similar experimental material in one block. And applying treatments in each block. • Two batches of raw material for hardness testing experiment.
  • 17. Guidelines for Designing an Experiments 1. Recognition of and statement of the problem 2. Selection of the response variable 3. Choice of factors, levels and ranges 4. Choice of experimental design 5. Performing the experiment 6. Statistical analysis of the data 7. Conclusions and recommendations The first three points are related to pre experimental planning
  • 18. Guidelines for Designing an Experiment 1. Recognition of and statement of the problem It is necessary to develop all ideas about the objectives of the experiment . Team approach is useful. Some of the reasons for running an experiment are a)Factor screening- To find most influential factors having impact on response variable. b)Optimization- To find settings or levels of the important factors that result in desirable values of response variable c)Confirmation- To verify some theory or past experience. Testing effectiveness of new substitute material d) Discovery To find new material e) RobustnessTo find the conditions under which response variable seriously degrade
  • 19. Guidelines for Designing an Experiment 2. Selection of the response variable It should give required information. The measurement system capability is important. 3. Choice of factors, levels and ranges The important factors having most influence are called design factors or nuisance factors. These are classified as controllable, uncontrollable and noise factors . The levels of controllable factor are set by experimenter. It is important to minimize the variability transmitted by noise factors . Cause –effect diagram , Fishbone diagram, process knowledge will be helpful in deciding levels.
  • 20. Guidelines for Designing an Experiment 4. Choice of experimental design It depends on the previous steps .There standard designs available. One can choose among them that best suits our experiment. Software are also available for deciding the design to be used. Model is also determined. it is the empirical relation between factors and response variable 5.Performing the experiment. Take utmost care to execute experiment as per plan. Any mistake will lead to increase in error.
  • 21. Guidelines for Designing an Experiment 6.Statistical analysis of the data It assures that the Conclusions are objective. Use graphical methods and Empirical model 7. Conclusions and recommendations Draw practical conclusions and recommend the action. Experimentation is a iterative procedure. Conduct series of small experiments instead of comprehensive experiment
  • 22. Best luck for better experimentation Thank you