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Copyright  ©  The McGraw-Hill Companies, Inc. Permission required for reproduction or display. Chapter 10 Molecular Biology of Inheritance
DNA Is the Genetic Material
10.1 DNA is a transforming substance ,[object Object],Figure 10.1 Griffith’s transformation experiment
10.2 DNA, not protein,  is the genetic material ,[object Object],[object Object],Figure 10.2A Structure of the virus (T2 bacteriophage) used by Hershey and Chase
Figure 10.2B Hershey and Chase experiment I
Figure 10.2C Hershey and Chase experiment II
10.3 DNA and RNA are  polymers of nucleotides ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Figure 10.3A DNA is a polynucleotide—contains many nucleotides
Figure 10.3B The four bases in DNA nucleotides
RNA ,[object Object],[object Object],[object Object],[object Object],Figure 10.3C The uracil nucleotide in RNA replaces thymine in DNA
10.4 DNA meets the criteria for the genetic material ,[object Object],[object Object],[object Object],[object Object]
Figure 10.4  Complementary  base pairing
10.5 DNA is a double helix ,[object Object],Figure 10.5A X-ray diffraction of DNA
Figure 10.5B The Watson and Crick model of DNA
DNA Can Be Duplicated
10.6 DNA replication is semiconservative ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Figure 10.6 Semiconservative replication (simplified)
10.7 Many different proteins  help DNA replicate Figure 10.7 DNA replication (in depth)
Genes Specify the Makeup of Proteins
10.8 Genes are linked to proteins Figure 10.8 Chemical basis of sickle-cell disease in humans
10.9 The making of a protein requires transcription and translation ,[object Object],[object Object],[object Object],[object Object]
Figure 10.9 Overview of gene expression
10.10 The genetic code for amino acids is a triplet code ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Figure 10.10  RNA codons
10.11 During transcription, a gene passes its coded information to an mRNA ,[object Object],[object Object],[object Object],[object Object]
Figure 10.11A Transcription:  synthesis of RNA
Figure 10.11B mRNA transcripts extending from horizontal DNA
10.12 In eukaryotes, an mRNA  is processed before  leaving the nucleus ,[object Object],[object Object],[object Object],[object Object],[object Object]
Figure 10.12 mRNA processing in eukaryotes
10.13 During translation,  each transfer RNA carries a  particular amino acid ,[object Object],[object Object],[object Object],[object Object]
Figure 10.13A Cloverleaf model  of tRNA
Figure 10.13B Space-filling model of tRNA molecule
10.14 Translation occurs at ribosomes in cytoplasm ,[object Object],[object Object]
Figure 10.14 Ribosome structure and function
10.15 Initiation begins the process  of polypeptide production ,[object Object],Figure 10.15 Initiation
10.16 Elongation builds a polypeptide  one amino acid at a time ,[object Object],Figure 10.16 Elongation cycle
10.17 Let’s review gene expression
 
Mutations Are Changes in the Sequence of DNA Bases
10.18 Mutations affect genetic information and expression ,[object Object],[object Object],[object Object]
Figure 10.18A Types of point mutations
APPLYING THE CONCEPTS—HOW BIOLOGY IMPACTS OUR LIVES 10.19 Many agents can  cause mutations ,[object Object],[object Object],[object Object],[object Object],[object Object]
APPLYING THE CONCEPTS—HOW SCIENCE PROGRESSES 10.20 Transposons are  “jumping genes” ,[object Object],[object Object],[object Object],[object Object],[object Object]
Connecting the Concepts: Chapter 10 ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

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