David Klatte (Pfizer) presented on this potential new working group during the "Dragons' Den" portion of the Pistoia Alliance Conference in Boston, MA, on April 24, 2012.
3. Imagine a World Without MOL
Chemical tools couldn’t talk to each other.
CROs would require custom formats (or pharma
companies would have to design a format and require
it of them)
Acquiring a large compound file would be a
nightmare
4.
5. There Is A Better Way
HELM: A Hierarchical Editing Language for
Macromolecules
Intuitive, Hierarchical, Extensible, Computer Readable,
Canonicalizable (and there are tools!)
6. Why a Pistoia Standard?
More complex than CTAB/MOL/SD.
Extensible means there is more than one way to do
things. One way needs to be agreed upon.
Pistoia is best positioned to publicize a standard.
A de facto standard for macromolecules would not
work.
7. ROI
Pharma invests less time figuring out how to interact
with CROs for macromolecules.
Software companies have a representation they can
use for interoperability.
Tools already exist. Everything won’t need to be
written from scratch.
Most of the hard work has been done already. Let’s
prove that Pistoia can create a standard.