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Adverse Events Following Immunization (AEFI)‏
Learning Objectives ,[object Object],[object Object],[object Object],At the end of the unit, you should be able to:
Contents ,[object Object],[object Object],[object Object],[object Object],[object Object]
What is an AEFI ? ,[object Object],[object Object],[object Object],[object Object],[object Object]
Is it really safe? ,[object Object],[object Object]
Types of AEFIs   ,[object Object],[object Object],[object Object],[object Object],[object Object]
1. Programmatic error ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],BCG injection given sub-cutaneously instead of Intradermally: local lymphadenitis and abcess
Types of Programmatic Errors Programmatic Errors Possible Adverse event that may occur  ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Re-use of disposable syringe and needle ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Vaccine transportation/storage incorrect ,[object Object],[object Object],Contraindications ignored ,[object Object]
2. Vaccine Reaction   Rare event caused by inherent properties of vaccine, not by Programmatic error. Child  has an allergic reaction to Vaccine.
True AEFIs ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
3. Coincidence   Event not caused by the vaccine (a chance association)‏ Child shows signs of measles a few days/ weeks after DPT vaccine is given.
4. Injection reaction   Event is caused by pain from (or fear about) the injection itself.  Child screams and faints at the sight of the needle.
5. Unknown Cause of  event cannot be determined. Child develops respiratory infection or fever a few days after Injection.
Elicit past history of AEFIs Ask parents about  history of any adverse reaction following earlier vaccinations, such as convulsion after DPT vaccination.
How to minimize AEFIs? ,[object Object]
[object Object],[object Object],How to minimize AEFIs?
[object Object],How to minimize AEFIs?
[object Object],[object Object],How to minimize AEFIs?
[object Object],How to minimize AEFIs?
[object Object],How to minimize AEFIs?
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],What to do if AEFI occurs?
Why Monitor AEFIs? ,[object Object],[object Object],[object Object],[object Object],[object Object]
What to Report? ,[object Object],[object Object],[object Object]
What not to Report?   Minor Reactions due to vaccines Mild vaccine reactions Treatment When to report Local reaction (pain, swelling, redness)‏ ,[object Object],[object Object],[object Object],Fever > 38.5 0 C ,[object Object],[object Object],[object Object],[object Object],[object Object],Irritability, malaise and systemic Symptoms ,[object Object],[object Object],[object Object]

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AEFI Immunization Basics

  • 1. Adverse Events Following Immunization (AEFI)‏
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  • 9. 2. Vaccine Reaction Rare event caused by inherent properties of vaccine, not by Programmatic error. Child has an allergic reaction to Vaccine.
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  • 11. 3. Coincidence Event not caused by the vaccine (a chance association)‏ Child shows signs of measles a few days/ weeks after DPT vaccine is given.
  • 12. 4. Injection reaction Event is caused by pain from (or fear about) the injection itself. Child screams and faints at the sight of the needle.
  • 13. 5. Unknown Cause of event cannot be determined. Child develops respiratory infection or fever a few days after Injection.
  • 14. Elicit past history of AEFIs Ask parents about history of any adverse reaction following earlier vaccinations, such as convulsion after DPT vaccination.
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