This document outlines the dermal filler Outline, which is an absorbable polyacrylamide. It has a half-life of 2 years for Outline Original and 5 years for Outline Ultra. It is metabolized by tissue esterases into smaller fragments that are eliminated, allowing for predictable breakdown. It can be injected at different tissue levels using thin needles and provides volume restoration with few side effects for up to a year. Contraindications include allergies, immunosuppression, infections and anticoagulant use.

1. DERMAL FILLERS OUTLINE - ABSORBABLE POLYACRYLAMIDE

9. INSERTION OF WEAK ESTER BONDS: DEFINING LENGTH

10. METABOLISM OF WEAK ESTER BONDS BY ESTERASES

14. OUTLINE ORIGINAL 0, 4 WEEKS, 6 MONTHS

16. FROWN LINE; 0 AND 1 YEAR