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T

A

C

A

G

G

A

G

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C

A

G

A

C

T

A

T

G

T

C

C

T

C

A

G

T

C

T

G

A
Cytoplasm

Nucleus

Ribosome
Cytoplasm

Nucleus

Ribosome
Cytoplasm

Nucleus

Ribosome
Cytoplasm

Nucleus

Ribosome
Cytoplasm

Nucleus

Ribosome
Nucleus

T

A

C

A

G

G

A

G

T

C

A

G

A

C

T

A

T

G

T

C

C

T

C

A

G

T

C

T

G

A
RNA
Polymerase

A

C

T

G

T

G

A

G

C

C

A

T

T

C

Coding Region

A

G

T

C

A

G

T

C

A

G

G

C

T

A

A

T

Promoter

Termination
sequence
TAC

RNA
Polymerase

A

C

T

G

T

G

A

G

C

C

A

T

T

C

Coding Region

A

G

T

C

A

G

T

C

A

G

G

C

T
A

A

T

Promoter

Termination
sequence
TAC

RNA
Polymerase

C

A

G

T

T

A

G

G

C

A

C

T

C

T

G

T

Coding Region

A

A

C

C

G

G

T

G

A

C

T

A

A

T

Promoter

Termination
sequence
TACAGG

RNA
Polymerase

T
A

C

G

G

T

C

A

G

T

C

A

Coding Region

A

T

C

C

G

C

T

G

T

A

A

G

G

C

T

A

A

T

Promoter

Termination
sequence
TACAGGAGT

RNA
Polymerase
C

T

G

A

C

T

G

T

A

A

A

Coding Region

G

T

C

C

G

T

C

A

G

T

C

A

G

G

C

T

A

A

T

Promoter

Termination
sequence
TACAGGAGTCAG

RNA
Polymerase

A

C

T

G

T

G

A

G

C

C

A

Coding Region

T

T

C

A

G

T

C

A

G

T

C

A

G

G

C

T

A

A

T

Promoter

Termination
sequence
TACAGGAGTCAGACT

A

C

T

G

U

G

A

G

C

C

A

U

T

C

Coding Region

A

G

U

C

A

G

U

C

A

G

G

C

U

A

A

T

Promoter

RNA
Polymerase

Termination
sequence
TACAGGAGTCAGACT

=mRNA strand

TACAGGAGTCAGACT

T

A

C

A

G

G

A

G

T

C

A

G

A

C

T

A

T

G

T

C

C

T

C

A

G

T

C

T

G

A
=mRNA
strand

Cytoplasm

Nucleus
Nuclear Pore
Ribosome
s
Amino
Acid

tRNA

AUG
Anti
Codo
n

TAC
Start
Codon

AGG

AGT

Codon

Codon

CAG

ACT

Codon

Stop
Codon
Large
ribosome
subunit
Amino
Acid

tRNA
AUG
TAC
Start
Codon

AGG

AGT

Codon
Small
ribosome
subunit

Codon

CAG

ACT

Codon

Stop
Codon
Large
ribosome
subunit
tRNA
Amino
Acid
UCC

tRNA
AUG
TAC
Start
Codon

AGG

AGT

Codon
Small
ribosome
subunit

Codon

CAG

ACT

Codon

Stop
Codon
Large
ribosome
subunit
Amino
Acid Peptide
bond
tRNA
tRNA
AUG

UCC

TAC

AGG

AGT

Codon
Small
ribosome
subunit

Codon

Start
Codon

CAG

ACT

Codon

Stop
Codon
RNA

Large
ribosome
subunit
Amino
Acid PeptidetRNA
bond
UCA
tRNA
AUG

UCC

TAC

AGG

AGT

Codon
Small
ribosome
subunit

Codon

Start
Codon

CAG

ACT

Codon

Stop
Codon
Large
ribosome
subunit
Amino
Acid Peptide
bond
tRNA

tRNA
AUG

UCC

TAC

AGG

AGT

Codon
Small
ribosome
subunit

Codon

Start
Codon

UCA
CAG

ACT

Codon

Stop
Codon
Large
ribosome
subunit
Amino
Acid Peptide
bond

tRNA
GUC

tRNA

tRNA
AUG

UCC

TAC

AGG

AGT

Codon
Small
ribosome
subunit

Codon

Start
Codon

UCA
CAG

ACT

Codon

Stop
Codon
Large
ribosome
subunit
Amino
Acid Peptide
bond

tRNA

tRNA
AUG

UCC

TAC

AGG

Start
Codon

Codon

UCA
AGT

GUC
CAG

Codon
Codon
Small
ribosome
subunit

ACT
Stop
Codon
tRNA

Large
ribosome
subunit

STOP
Amino
Acid Peptide
bond

tRNA
AUG

UCC

TAC

AGG

Start
Codon

Codon

UCA
AGT

GUC
CAG

Codon
Codon
Small
ribosome
subunit

ACT
Stop
Codon
Large
ribosome
subunit
Amino
Acid Peptide
bond
tRNA
AUG

UCC

TAC

AGG

Start
Codon

Codon

UCA
AGT

GUC
CAG

Codon
Codon
Small
ribosome
subunit

STOP
ACT
Stop
Codon
Large
ribosome
subunit
Amino
Acid Peptide
bond
tRNA
AUG

UCC

TAC

AGG

Start
Codon

Codon

UCA
AGT

GUC
CAG

Codon
Codon
Small
ribosome
subunit

STOP
ACT
Stop
Codon
Large
ribosome
subunit
Amino
Acid Peptide
bond

tRNA
AUG

UCC

TAC

AGG

Start
Codon

Codon

UCA
AGT

GUC
CAG

Codon
Codon
Small
ribosome
subunit

STOP
ACT
Stop
Codon
Large
ribosome
subunit
Amino
Acid Peptide
bond

AUG

UCC

TAC

AGG

Start
Codon

Codon

UCA
AGT

GUC
CAG

Codon
Codon
Small
ribosome
subunit

STOP
ACT
Stop
Codon
Protein Synthesis
• Protein synthesis has two steps, which are transcription
and translation. Transcription is first and RNA
polymerase binds onto the double helix strand. It then
works it way down the DNA and temporarily unwinds
it. It also builds a mRNA strand of the top part of DNA.
When the mRNA strand is built the DNA goes back
together. When it is finished the mRNA strand breaks
off and leaves the nucleus through little holes called
nuclear pores. When it is in the cytoplasm it gets on a
ribosome and that leads to the next step. It starts at
the promoter and ends with the termination sequence.
Everything in between is called the coding region.
Protein Synthesis(Con.)
• Translation is the second step of protein synthesis.
When the mRNA strand leaves the nucleus it catches
onto a ribosome. tRNA messengers then carry in both
an anti codon and an amino acid. When the next tRNA
messenger comes in a peptide bond is formed between
the amino acids and the first tRNA messenger goes
away. This continues on until it get to the stop codon
which is ACT. When it gets to stop the amino acids
break off and start to fold up on itself, which then
makes it a protein. The way the protein folds up on
itself tells what the function is.

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