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The Peripheral
Nervous System

     PART 3
Peripheral Nervous System
The Peripheral Nervous System
• Nervous structures outside the brain and
    spinal cord
•   Nerves allow the CNS to receive
    information and take action
•   Functional components of the PNS
    • Sensory inputs and motor outputs
        categorized as somatic or visceral
    •   Sensory inputs also classified as general or
        special
Sensory Input and Motor Output
• Sensory (afferent) signals picked up by sensor receptors,
    carried by nerve fibers of PNS to the CNS
•   Motor (efferent) signals are carried away from the CNS,
    innervate muscles and glands
•   Divided according to region they serve
    • Somatic body region
    • Visceral body region
• Results in four main subdivisions
    •   Somatic sensory
    •   Visceral sensory
    •   Somatic motor
    •   Visceral motor
PNS Afferent Division
• Afferent (sensory) division – transmits impulses from
  receptors to the CNS.
   • Somatic afferent fibers – carry impulses from skin, skeletal
       muscles, and joints
   •   Visceral afferent fibers – transmit impulses from visceral
       organs
PNS Efferent Division
• Motor (efferent) division – transmits impulses from the CNS to
   effector organs. Two subdivisions:
    • Somatic nervous system – provides conscious control of skeletal
       muscles
    • Autonomic nervous system – regulates smooth muscle, cardiac
       muscle, and glands
Types of Sensory and Motor Information




                                 Figure 12.3
Sensory
• General somatic senses – include touch,
    pain, vibration, pressure, temperature
•   Proprioceptive senses – detect stretch in
    tendons and muscle provide information on
    body position, orientation and movement of
    body in space
•   Special Senses - hearing, balance, vision,
    olfaction (smell), gustation (taste)
Motor
• General somatic motor
  • Signals contraction of skeletal muscles
  • Under our voluntary control
• Visceral motor
  • Makes up autonomic nervous system (ANS)
  • Regulates the contraction of smooth and
    cardiac muscle, controls function of visceral
    organs
  • ANS has two divisions
     • Parasympathetic
     • Sympathetic
Divisions of the ANS
• Sympathetic - “fight or flight”
    •   Catabolic (expend energy)
    •   Mass activation prepares for intense
        activity.
         • Heart rate (HR) increases.
         • Bronchioles dilate.
         • Blood [glucose] increases.
• Parasympathetic - “feed & breed”, “rest
   & digest”
    •   Maintain homeostasis
    •   Normally not activated as a whole,
        stimulation of separate
        parasympathetic nerves.
    •   Relaxing effects:
         • Decreases HR.
         • Dilates visceral blood vessels.
         • Increases digestive activity.
• Dual innervation of many organs —
   having a brake and an accelerator
   provides more control
Sympathetic Division Organization
• Preganglionic neurons in
   segments T1 to L2
• Ganglia near the vertebral
   column
• Sympathetic ganglia
    • Paired sympathetic chain
       ganglia
    • Unpaired collateral ganglia
• Preganglionic fibers to adrenal
   medullae
    • Epinephrine (adrenalin) into
       blood stream
The Autonomic Nervous System

• Effects of Sympathetic Activation
  • Generalized response in crises
  • Increased alertness/energy
  • Increased cardiovascular activity
  • Increased respiratory activity
  • Increased muscle tone
Parasympathetic Division Organization

• Preganglionic neurons in
    brain stem and sacral
    spinal segment
•   Ganglionic neurons
    (peripheral ganglia) in or
    near target organ
•   Sacral fibers form pelvic
    nerves
The Autonomic Nervous System

• Effects of Parasympathetic Activation
  • Relaxation
  • Food processing
  • Energy absorption
  • Brief effects at specific sites
Basic Structural Components of the PNS
• Sensory receptors – pick up stimuli from inside or outside the body
• Motor endings – axon terminals of motor neurons innervate effectors
    (muscle fibers and glands)
•   Nerves and ganglia
     • Nerves – bundles of peripheral axons
     • Ganglia – clusters of peripheral neuronal cell bodies
Nerves
• Nerves – cablelike organs in the
    PNS
•   Consists of numerous axons
    wrapped in connective tissue
    • Endoneurium – layer of delicate
      connective tissue surrounding the axon
    • Perineurium – connective tissue wrapping
      surrounding a nerve fascicle
    • Nerve fascicles – groups of axons bound into
      bundles
    • Epineurium – whole nerve is surrounded
      by tough fibrous sheath
• Axon is surrounded by Schwann
    cells
Cranial Nerves
• Attach to the brain and pass through
    foramina of the skull
•   Numbered from I–XII
•   Cranial nerves I and II attach to the
    forebrain
    • All others attach to the brain stem
• Primarily serve head and neck structures
    • The vagus nerve (X) extends into the
      abdomen
The 12 Pairs of Cranial Nerves




                                 Figure 14.5
Olfactory Nerves (I)
• Sensory nerves of smell
                                     olfactory nerve (I)
                                     Olfactory bulb
                                     Olfactory tract
                                     Optic nerve (II)
                                     Optic chiasma

                                     Optic tract
                                     Oculomotor nerve (III)

                                     Trochlear nerve (IV)
                                     Trigeminal nerve (V)


                                     Abducens nerve (VI)


                                     Cerebellum
                                     Medulla



                                 Table 14.3 (1 of 12)
Optic Nerve (II)
• Sensory nerve of vision

                                     Filaments of
                                     olfactory nerve (I)
                                     Olfactory bulb
                                     Olfactory tract
                                     Optic nerve (II)
                                     Optic chiasma

                                     Optic tract
                                     Oculomotor nerve (III)

                                     Trochlear nerve (IV)
                                     Trigeminal nerve (V)


                                     Abducens nerve (VI)


                                     Cerebellum
                                     Medulla


                                Table 14.3 (2 of 12)
Oculomotor Nerve (III)
• Innervates four of the extrinsic eye muscles

                                           Filaments of
                                           olfactory nerve (I)
                                           Olfactory bulb
                                           Olfactory tract
                                           Optic nerve (II)
                                           Optic chiasma

                                           Optic tract
                                        Oculomotor nerve (III)
                                           Trochlear nerve (IV)
                                           Trigeminal nerve (V)


                                           Abducens nerve (VI)


                                           Cerebellum
                                           Medulla


                                      Table 14.3 (3 of 12)
Trochlear Nerve (IV)
• Innervates the superior oblique muscle (an
  extrinsic eye muscle)

                                               Filaments of
                                               olfactory nerve (I)
                                               Olfactory bulb
                                               Olfactory tract
                                               Optic nerve (II)
                                               Optic chiasma

                                               Optic tract
                                               Oculomotor nerve (III)

                                               Trochlear nerve
                                               (IV)
                                               Trigeminal nerve (V)


                                               Abducens nerve (VI)


                                               Cerebellum
                                               Medulla


                                          Table 14.3 (4 of 12)
Trigeminal Nerve (V)
• Provides sensory innervation to the face
• Motor innervation to chewing muscles

                                              Filaments of
                                              olfactory nerve (I)
                                              Olfactory bulb
                                              Olfactory tract
                                              Optic nerve (II)
                                              Optic chiasma

                                              Optic tract
                                              Oculomotor nerve (III)

                                              Trochlear nerve (IV)

                                             Trigeminal nerve (V)

                                              Abducens nerve (VI)


                                              Cerebellum
                                              Medulla
Abducens Nerve (VI)
• Abducts the eyeball – innervates lateral
  rectus muscle
                                           Filaments of
                                           olfactory nerve (I)
                                           Olfactory bulb
                                           Olfactory tract
                                           Optic nerve (II)
                                           Optic chiasma

                                           Optic tract
                                           Oculomotor nerve (III)

                                           Trochlear nerve (IV)
                                           Trigeminal nerve (V)


                                          Abducens nerve (VI)

                                           Cerebellum
                                           Medulla


                                      Table 14.3 (6 of 12)
Facial Nerve (VII)
• Innervates muscles of facial expression




                           Facial nerve (VII)
                            Vestibulocochlear
                            nerve (VIII)


                            Glossopharyngeal
                            nerve (IX)
                            Vagus nerve (X)
                            Accessory nerve (XI)
                            Hypoglossal nerve (XII)


                                                      Table 14.3 (7 of 12)
Vestibulocochlear Nerve (VIII)
• Sensory nerve of hearing and balance




                         Facial nerve (VII)

                        Vestibulocochlear
                        nerve (VIII)

                         Glossopharyngeal
                         nerve (IX)
                         Vagus nerve (X)
                         Accessory nerve (XI)
                         Hypoglossal nerve (XII)


                                                   Table 14.3 (8 of 12)
Glossopharyngeal Nerve (IX)
• Innervates structures of the tongue and
  pharynx




                          Facial nerve (VII)

                          Vestibulocochlear
                          nerve (VIII)

                         Glossopharyngeal
                         nerve (IX)
                          Vagus nerve (X)
                          Accessory nerve (XI)
                          Hypoglossal nerve (XII)

                                                    Table 14.3 (9 of 12)
Vagus Nerve (X)
• A mixed sensory and motor nerve - “Wanders” into thorax and abdomen




                                     Facial nerve (VII)

                                     Vestibulocochlear
                                     nerve (VIII)


                                     Glossopharyngeal
                                     nerve (IX)
                                     Vagus nerve (X)
                                     Accessory nerve (XI)
                                     Hypoglossal nerve (XII)


                                                               Table 14.3 (10 of 12)
Accessory Nerve (XI)
• An accessory part of the vagus nerve -innervates
  trapezius muscle




                              Facial nerve (VII)

                              Vestibulocochlear
                              nerve (VIII)

                              Glossopharyngeal
                              nerve (IX)
                              Vagus nerve (X)
                            Accessory nerve (XI)
                              Hypoglossal nerve (XII)

                                                        Table 14.3 (11 of 12)
Hypoglossal Nerve (XII)
• Runs inferior to the tongue - innervates the tongue
  muscles




                               Facial nerve (VII)

                               Vestibulocochlear
                               nerve (VIII)

                               Glossopharyngeal
                               nerve (IX)
                               Vagus nerve (X)
                               Accessory nerve (XI)
                             Hypoglossal nerve (XII)

                                                       Table 14.3 (12 of 12)
Spinal Nerves
• 31 pairs – contain thousands of
    nerve fibers
•   Connect to the spinal cord
•   Named for point of issue from the
    spinal cord
     •   8 pairs of cervical nerves (C1–C8)
     •   12 pairs of thoracic nerves (T1–T12)
     •   5 pairs of lumbar nerves (L1–L5)
     •   5 pairs of sacral nerves (S1–S5)
     •   1 pair of coccygeal nerves (Co1)
Spinal Nerves
• Connect to the spinal cord
    by the dorsal root and
    ventral root
     • Dorsal root – contains
         sensory fibers
     •   Dorsal root ganglion – of
         afferent cell bodies
     •   Ventral root – contains
         motor fibers arising from
         anterior gray column
• Branch into dorsal ramus
    and ventral ramus both
    contain sensory and motor
    fibers
•   Rami communicantes
    connect to the base of the
    ventral ramus and lead to
    the sympathetic chain
    ganglia
Spinal Nerves

                  Ventral root                   White matter
                  Dorsal root                    Gray matter
Dorsal root                                      Dorsal and ventral
ganglion                                         rootlets of spinal
Dorsal ramus                                     nerve
of spinal nerve
Ventral ramus
of spinal nerve
Spinal nerve
Rami communicantes
Sympathetic trunk
(chain) ganglion

(a)
Innervation of the Back
• Dorsal rami
  •   Innervate back muscles
  •   Follow a neat, segmented pattern
  •   Innervate a horizontal strip of muscle and skin
  •   In line with emergence point from the vertebral column
Innervation of the Thoracic region
• Ventral rami arranged in simple, segmented pattern
• Intercostal nerves – supply intercostal muscles, skin, and
  abdominal wall
    • Each gives off lateral and anterior cutaneous branches
Introduction to Nerve Plexuses
• Nerve plexus – a network of
    nerves
•   Ventral rami (except T2 – T12)
     • Branch and join with one
         another
     •   Form nerve plexuses
          •   Cervical
          •   Brachial
          •   Lumbar
          •   Sacral
     • Primarily serve the limbs
     • Fibers from ventral rami
         crisscross
The Cervical Plexus
•   Buried deep in the neck under the sternocleidomastoid muscle
•   Formed by ventral rami of first four cervical nerves (C 1 – 4)
•   Most are cutaneous nerves
•   Some innervate muscles of the anterior neck
Brachial Plexus
• Brachial plexus lies in the neck and axilla
• Formed by ventral rami of C5 – C8 give rise to cords
• Cords give rise to main nerves of the upper limb




                                                         Figure 14.9d
Lumbar Plexus
• Arises from L1– L4
• Smaller branches innervate the posterior abdominal wall and psoas
    muscle
•   Main branches innervate the anterior thigh
The Sacral Plexus
•   Arises from spinal nerves L4–S4
•   Often considered with the lumbar plexus referred to as the lumbosacral plexus
•   Sciatic nerve – the largest nerve of the sacral plexus is actually two nerves in one sheath
     • Tibial nerve – innervates most of the posterior lower limb
     • Common fibular (peroneal) nerve – innervates muscles of the anterolateral leg

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2304 nervouspart3

  • 3. The Peripheral Nervous System • Nervous structures outside the brain and spinal cord • Nerves allow the CNS to receive information and take action • Functional components of the PNS • Sensory inputs and motor outputs categorized as somatic or visceral • Sensory inputs also classified as general or special
  • 4. Sensory Input and Motor Output • Sensory (afferent) signals picked up by sensor receptors, carried by nerve fibers of PNS to the CNS • Motor (efferent) signals are carried away from the CNS, innervate muscles and glands • Divided according to region they serve • Somatic body region • Visceral body region • Results in four main subdivisions • Somatic sensory • Visceral sensory • Somatic motor • Visceral motor
  • 5. PNS Afferent Division • Afferent (sensory) division – transmits impulses from receptors to the CNS. • Somatic afferent fibers – carry impulses from skin, skeletal muscles, and joints • Visceral afferent fibers – transmit impulses from visceral organs
  • 6. PNS Efferent Division • Motor (efferent) division – transmits impulses from the CNS to effector organs. Two subdivisions: • Somatic nervous system – provides conscious control of skeletal muscles • Autonomic nervous system – regulates smooth muscle, cardiac muscle, and glands
  • 7. Types of Sensory and Motor Information Figure 12.3
  • 8. Sensory • General somatic senses – include touch, pain, vibration, pressure, temperature • Proprioceptive senses – detect stretch in tendons and muscle provide information on body position, orientation and movement of body in space • Special Senses - hearing, balance, vision, olfaction (smell), gustation (taste)
  • 9. Motor • General somatic motor • Signals contraction of skeletal muscles • Under our voluntary control • Visceral motor • Makes up autonomic nervous system (ANS) • Regulates the contraction of smooth and cardiac muscle, controls function of visceral organs • ANS has two divisions • Parasympathetic • Sympathetic
  • 10. Divisions of the ANS • Sympathetic - “fight or flight” • Catabolic (expend energy) • Mass activation prepares for intense activity. • Heart rate (HR) increases. • Bronchioles dilate. • Blood [glucose] increases. • Parasympathetic - “feed & breed”, “rest & digest” • Maintain homeostasis • Normally not activated as a whole, stimulation of separate parasympathetic nerves. • Relaxing effects: • Decreases HR. • Dilates visceral blood vessels. • Increases digestive activity. • Dual innervation of many organs — having a brake and an accelerator provides more control
  • 11. Sympathetic Division Organization • Preganglionic neurons in segments T1 to L2 • Ganglia near the vertebral column • Sympathetic ganglia • Paired sympathetic chain ganglia • Unpaired collateral ganglia • Preganglionic fibers to adrenal medullae • Epinephrine (adrenalin) into blood stream
  • 12. The Autonomic Nervous System • Effects of Sympathetic Activation • Generalized response in crises • Increased alertness/energy • Increased cardiovascular activity • Increased respiratory activity • Increased muscle tone
  • 13. Parasympathetic Division Organization • Preganglionic neurons in brain stem and sacral spinal segment • Ganglionic neurons (peripheral ganglia) in or near target organ • Sacral fibers form pelvic nerves
  • 14. The Autonomic Nervous System • Effects of Parasympathetic Activation • Relaxation • Food processing • Energy absorption • Brief effects at specific sites
  • 15. Basic Structural Components of the PNS • Sensory receptors – pick up stimuli from inside or outside the body • Motor endings – axon terminals of motor neurons innervate effectors (muscle fibers and glands) • Nerves and ganglia • Nerves – bundles of peripheral axons • Ganglia – clusters of peripheral neuronal cell bodies
  • 16. Nerves • Nerves – cablelike organs in the PNS • Consists of numerous axons wrapped in connective tissue • Endoneurium – layer of delicate connective tissue surrounding the axon • Perineurium – connective tissue wrapping surrounding a nerve fascicle • Nerve fascicles – groups of axons bound into bundles • Epineurium – whole nerve is surrounded by tough fibrous sheath • Axon is surrounded by Schwann cells
  • 17. Cranial Nerves • Attach to the brain and pass through foramina of the skull • Numbered from I–XII • Cranial nerves I and II attach to the forebrain • All others attach to the brain stem • Primarily serve head and neck structures • The vagus nerve (X) extends into the abdomen
  • 18. The 12 Pairs of Cranial Nerves Figure 14.5
  • 19. Olfactory Nerves (I) • Sensory nerves of smell olfactory nerve (I) Olfactory bulb Olfactory tract Optic nerve (II) Optic chiasma Optic tract Oculomotor nerve (III) Trochlear nerve (IV) Trigeminal nerve (V) Abducens nerve (VI) Cerebellum Medulla Table 14.3 (1 of 12)
  • 20. Optic Nerve (II) • Sensory nerve of vision Filaments of olfactory nerve (I) Olfactory bulb Olfactory tract Optic nerve (II) Optic chiasma Optic tract Oculomotor nerve (III) Trochlear nerve (IV) Trigeminal nerve (V) Abducens nerve (VI) Cerebellum Medulla Table 14.3 (2 of 12)
  • 21. Oculomotor Nerve (III) • Innervates four of the extrinsic eye muscles Filaments of olfactory nerve (I) Olfactory bulb Olfactory tract Optic nerve (II) Optic chiasma Optic tract Oculomotor nerve (III) Trochlear nerve (IV) Trigeminal nerve (V) Abducens nerve (VI) Cerebellum Medulla Table 14.3 (3 of 12)
  • 22. Trochlear Nerve (IV) • Innervates the superior oblique muscle (an extrinsic eye muscle) Filaments of olfactory nerve (I) Olfactory bulb Olfactory tract Optic nerve (II) Optic chiasma Optic tract Oculomotor nerve (III) Trochlear nerve (IV) Trigeminal nerve (V) Abducens nerve (VI) Cerebellum Medulla Table 14.3 (4 of 12)
  • 23. Trigeminal Nerve (V) • Provides sensory innervation to the face • Motor innervation to chewing muscles Filaments of olfactory nerve (I) Olfactory bulb Olfactory tract Optic nerve (II) Optic chiasma Optic tract Oculomotor nerve (III) Trochlear nerve (IV) Trigeminal nerve (V) Abducens nerve (VI) Cerebellum Medulla
  • 24. Abducens Nerve (VI) • Abducts the eyeball – innervates lateral rectus muscle Filaments of olfactory nerve (I) Olfactory bulb Olfactory tract Optic nerve (II) Optic chiasma Optic tract Oculomotor nerve (III) Trochlear nerve (IV) Trigeminal nerve (V) Abducens nerve (VI) Cerebellum Medulla Table 14.3 (6 of 12)
  • 25. Facial Nerve (VII) • Innervates muscles of facial expression Facial nerve (VII) Vestibulocochlear nerve (VIII) Glossopharyngeal nerve (IX) Vagus nerve (X) Accessory nerve (XI) Hypoglossal nerve (XII) Table 14.3 (7 of 12)
  • 26. Vestibulocochlear Nerve (VIII) • Sensory nerve of hearing and balance Facial nerve (VII) Vestibulocochlear nerve (VIII) Glossopharyngeal nerve (IX) Vagus nerve (X) Accessory nerve (XI) Hypoglossal nerve (XII) Table 14.3 (8 of 12)
  • 27. Glossopharyngeal Nerve (IX) • Innervates structures of the tongue and pharynx Facial nerve (VII) Vestibulocochlear nerve (VIII) Glossopharyngeal nerve (IX) Vagus nerve (X) Accessory nerve (XI) Hypoglossal nerve (XII) Table 14.3 (9 of 12)
  • 28. Vagus Nerve (X) • A mixed sensory and motor nerve - “Wanders” into thorax and abdomen Facial nerve (VII) Vestibulocochlear nerve (VIII) Glossopharyngeal nerve (IX) Vagus nerve (X) Accessory nerve (XI) Hypoglossal nerve (XII) Table 14.3 (10 of 12)
  • 29. Accessory Nerve (XI) • An accessory part of the vagus nerve -innervates trapezius muscle Facial nerve (VII) Vestibulocochlear nerve (VIII) Glossopharyngeal nerve (IX) Vagus nerve (X) Accessory nerve (XI) Hypoglossal nerve (XII) Table 14.3 (11 of 12)
  • 30. Hypoglossal Nerve (XII) • Runs inferior to the tongue - innervates the tongue muscles Facial nerve (VII) Vestibulocochlear nerve (VIII) Glossopharyngeal nerve (IX) Vagus nerve (X) Accessory nerve (XI) Hypoglossal nerve (XII) Table 14.3 (12 of 12)
  • 31. Spinal Nerves • 31 pairs – contain thousands of nerve fibers • Connect to the spinal cord • Named for point of issue from the spinal cord • 8 pairs of cervical nerves (C1–C8) • 12 pairs of thoracic nerves (T1–T12) • 5 pairs of lumbar nerves (L1–L5) • 5 pairs of sacral nerves (S1–S5) • 1 pair of coccygeal nerves (Co1)
  • 32. Spinal Nerves • Connect to the spinal cord by the dorsal root and ventral root • Dorsal root – contains sensory fibers • Dorsal root ganglion – of afferent cell bodies • Ventral root – contains motor fibers arising from anterior gray column • Branch into dorsal ramus and ventral ramus both contain sensory and motor fibers • Rami communicantes connect to the base of the ventral ramus and lead to the sympathetic chain ganglia
  • 33. Spinal Nerves Ventral root White matter Dorsal root Gray matter Dorsal root Dorsal and ventral ganglion rootlets of spinal Dorsal ramus nerve of spinal nerve Ventral ramus of spinal nerve Spinal nerve Rami communicantes Sympathetic trunk (chain) ganglion (a)
  • 34. Innervation of the Back • Dorsal rami • Innervate back muscles • Follow a neat, segmented pattern • Innervate a horizontal strip of muscle and skin • In line with emergence point from the vertebral column
  • 35. Innervation of the Thoracic region • Ventral rami arranged in simple, segmented pattern • Intercostal nerves – supply intercostal muscles, skin, and abdominal wall • Each gives off lateral and anterior cutaneous branches
  • 36. Introduction to Nerve Plexuses • Nerve plexus – a network of nerves • Ventral rami (except T2 – T12) • Branch and join with one another • Form nerve plexuses • Cervical • Brachial • Lumbar • Sacral • Primarily serve the limbs • Fibers from ventral rami crisscross
  • 37. The Cervical Plexus • Buried deep in the neck under the sternocleidomastoid muscle • Formed by ventral rami of first four cervical nerves (C 1 – 4) • Most are cutaneous nerves • Some innervate muscles of the anterior neck
  • 38. Brachial Plexus • Brachial plexus lies in the neck and axilla • Formed by ventral rami of C5 – C8 give rise to cords • Cords give rise to main nerves of the upper limb Figure 14.9d
  • 39. Lumbar Plexus • Arises from L1– L4 • Smaller branches innervate the posterior abdominal wall and psoas muscle • Main branches innervate the anterior thigh
  • 40. The Sacral Plexus • Arises from spinal nerves L4–S4 • Often considered with the lumbar plexus referred to as the lumbosacral plexus • Sciatic nerve – the largest nerve of the sacral plexus is actually two nerves in one sheath • Tibial nerve – innervates most of the posterior lower limb • Common fibular (peroneal) nerve – innervates muscles of the anterolateral leg