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SOME DISEASES CAUSED BY FILAMENTOUS FUNGI ,[object Object],[object Object],[object Object],[object Object],www.freelivedoctorcom
CHROMOBLASTOMYCOSIS A chronic localized infection of the subcutaneous tissue caused by several species of dematiaceous fungi www.freelivedoctorcom
Chromoblastomycosis Fonsecaea  pedrosoi Cladosporium carrionii Phialophora verrucosa www.freelivedoctorcom
Ecological Association Chromoblastomycosis ,[object Object],[object Object],www.freelivedoctorcom
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Sclerotic  Bodies A fungus form resulting from host defenses www.freelivedoctorcom
SCLEROTIC BODIES www.freelivedoctorcom
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Chromoblastomycosis Melanin may be a virulence factor www.freelivedoctorcom
Geographic distribution World-wide (usually warmer climates) www.freelivedoctorcom
CLINICAL SPECIMENS ,[object Object],[object Object],www.freelivedoctorcom
TREATMENT ,[object Object],[object Object],[object Object],[object Object],www.freelivedoctorcom
No Serological Tests Available www.freelivedoctorcom
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Mycetoma ,[object Object],[object Object],[object Object],[object Object],[object Object],www.freelivedoctorcom
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Mycetoma agents ,[object Object],[object Object],[object Object],www.freelivedoctorcom
GEOGRAPHIC DISTRIBUTION WARM CLIMATES (SE United States, South America, Africa) www.freelivedoctorcom
ECOLOGICAL ASSOCIATION SOIL www.freelivedoctorcom
Clinical Specimens Mycetoma ,[object Object],[object Object],www.freelivedoctorcom
IDENTIFICATION ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],www.freelivedoctorcom
De DEMATIACEOUS HYPHAE www.freelivedoctorcom
Serological Test Pseudalescheria Immunodiffusion www.freelivedoctorcom
Therapy Terbinefine Itraconazole Posaconazole www.freelivedoctorcom
Mucormycosis An acute infection characterized by inflammation and vascular invasion and thrombosis. www.freelivedoctorcom
Portal of entry ,[object Object],[object Object],[object Object],www.freelivedoctorcom
Mucormycosis *Rhizopus species Mucor species Absidia species. www.freelivedoctorcom
GEOGRAPHIC DISTRIBUTION WORLDWIDE www.freelivedoctorcom
ECOLOGICAL NICHE ,[object Object],[object Object],[object Object],[object Object],www.freelivedoctorcom
UNCONTROLLED DIABETIC Rapidly fatal www.freelivedoctorcom
MUCORMYCOSIS ,[object Object],[object Object],[object Object],[object Object],[object Object],www.freelivedoctorcom
CHARACTERISITICS OF MUCOR INFECTION ,[object Object],[object Object],[object Object],[object Object],www.freelivedoctorcom
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WIDE,  NON-SEPTATE, RIBBON-LIKE www.freelivedoctorcom
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TREATMENT ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],www.freelivedoctorcom
SEROLOGIC TEST ,[object Object],www.freelivedoctorcom
ASPERGILLOSIS A variety of diseases: pulmonary, external ears, eyes, meninges, sinuses or blood stream www.freelivedoctorcom
CLINICAL TYPES OF PULMONARY DISEASE ,[object Object],[object Object],[object Object],www.freelivedoctorcom
Difficult to diagnose ,[object Object],[object Object],[object Object],[object Object],[object Object],www.freelivedoctorcom
COMMON PATHOGENIC SPECIES ,[object Object],[object Object],[object Object],www.freelivedoctorcom
GEOGRAPHIC DISTRIBUTION WORLD-WIDE www.freelivedoctorcom
ECOLOGICAL ASSOCIATION ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],www.freelivedoctorcom
Culture ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],www.freelivedoctorcom
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HISTOPATHOLOGY ,[object Object],[object Object],www.freelivedoctorcom
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DICHOTOMOUS BRANCHING www.freelivedoctorcom
Aspergilloma Cavity  wall www.freelivedoctorcom
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SEROLOGIC TESTS ,[object Object],[object Object],[object Object],[object Object],www.freelivedoctorcom
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DRUG OF CHOICE VORICONAZOLE AMPHOTERICIN B www.freelivedoctorcom
DIMORPHIC FUNGI (Endemic Mycoses) ,[object Object],[object Object],[object Object],[object Object],[object Object],www.freelivedoctorcom
BLASTOMYCOSIS Blastomyces dermatitidis www.freelivedoctorcom
BLASTOMYCOSIS A CHRONIC SUPPURATIVE AND GRANULOMATOUS DISEASE OF ANY TISSUE WITH A PREDILECTION FOR LUNGS, SKIN, PROSTATE AND BONE. www.freelivedoctorcom
PORTAL OF ENTRY ,[object Object],[object Object],[object Object],www.freelivedoctorcom
CLINICAL FORMS ,[object Object],[object Object],[object Object],[object Object],[object Object],www.freelivedoctorcom
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Pulmonary Symptoms ,[object Object],[object Object],[object Object],[object Object],[object Object],www.freelivedoctorcom
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CLINICAL SPECIMENS ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],www.freelivedoctorcom
ECOLOGICAL ASSOCIATION ORGANIC DEBRIS (SOIL, ROTTED WOOD, DECAYED VEGETATION)  www.freelivedoctorcom
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Virulence Factor BAD1 www.freelivedoctorcom
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Identification ,[object Object],[object Object],[object Object],www.freelivedoctorcom
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Wet Mount  www.freelivedoctorcom
SEROLOGIC TEST ,[object Object],[object Object],[object Object],www.freelivedoctorcom
DRUGS OF CHOICE ,[object Object],[object Object],[object Object],www.freelivedoctorcom
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Filamentous Fungi

Notes de l'éditeur

  1. ECOLOGICAL
  2. Wide, non-septate,mycelium. Ribbon-like