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RecuRRent
  AbdominAl
     PAin
Dr. Ravi Malik
CMD Radix Hospital
IMA Headquaters
DMC medical education
 convenor
INTRODUCTION
RAP
 3 episodes over 3 months
 Severe enough to affect activities
 Inter periods of well being
  No specific cause identified
epIDemIOlOgy
10-12% of school aged children.
Peak incidence at 4-6 years and at 7-12
 years.
Obesity and RAP.
Fruits consumption and RAP.
ClINICal pROfIle
Pain is genuine
Peri-umbilical pain
Nausea, vomiting
Pallor
Headache & limb pains
Family history
ClassIfICaTION
• It can be organic or nonorganic.
• Nonorganic(functional) abd pain
  • Functional dyspepsia
  • Irritable bowel syndrome
  • Abdominal migraine
  • Functional abdominal pain
eTIOlOgy
                          Organic Pain (10%)   Non-organic Pain (90%)
Site                      Flanks, suprapubic   Central and often epigastric
Family History                    - VE                     + VE
Psychological History             - VE                     + VE
Headache                          - VE                     + VE
Weight Loss                       +VE                      - VE
Abnormal Signs                    +VE                      - VE
Abnormal Investigations           +VE                      - VE
Alarming Symptoms                 + VE                     - VE
Functional dyspepsia
 Pain or discomfort in the upper abd.
 Stomach fullness
 Bloating
 Nausea
 Retching or vomiting.


Irritable bowel syndrome
Abdominal migraine
 Intense abdominal pain
 Mid-abdomen
 Anorexia, nausea, vomiting, pallor,
  headache, or sensitivity to light
 A family history of migraine


Functional abdominal pain syndrome
Rap (ORgaNIC)
GIT
 Infections – ameba, giardia, dysentry, H.
  pylori
 Inflammatory-IBD, Hepatitis,
  appendicitis
 Constipation
 GI reflux disease
 Acid peptic disease
CaUses Of Rap
Urinary tract (ORgaNIC)
                Gynecological Miscellaneous

Urinary tract     Ovarian cyst
infection                         Abdominal
Urinary calculi                   epilepsy
                  Endometriosis
Pelvi-ureteric                    Physical,
junction          Pelvic          emotional and
obstruction       inflammatory    sexual abuse
                  disease
Chronic
pancreatitis
paThOphysIOlOgy
Gastrointestinal motility- High levels of
 emotional stress and abnormalities in
 autonomic nervous system may contribute.

Visceral hypersensitivity-
Intensity of signals from GIT is exaggerated.
Abnormal bowel sensitivity to physiological,
 psychologic or noxious stimuli may be present.
May occur following viral gastroenteritis or
 after psychologically traumatic events.
Emotional stress
Patients can sometimes date the onset of pain to
 a specific stressful event, such as change in school,
 birth of a sibling or separation of parents, family
 member's illess.
Higher levels of anxiety and depression are found
 in patients with RAP than in healthy children.
Starting school may also trigger recurrent
 abdominal pain.
Psychological factors:-
A child can develop chronic abdominal pain related
 to his or her need for attention.
Parental response to child's pain can reinforce the
 child's behavior. If parents are worried about child's
 pain, the child may become more anxious, and the
 pain may worsen.
Parents should pay attention to the child's other
 activities, this might satisfy the child's need for
 attention & reduce the abdominal pain.
alaRm sympTOms
       (NeeDINg fURTheR INvesTIgaTIONs)

  Features that suggest an organic disorder may include one or
  more of the following:
 Pain that awakens the child,
 Significant vomiting/constipation/bloating
 Persistent right upper/lower quadrant pain
 Unexplained fever
 Dysphagia
 Chronic severe diarrhea
 G.I. blood loss
 Unintentional weight loss or slowed growth
 Delayed puberty
 Pain/ bleeding with urination
 Family H/O inflammatory bowel disease, celiac or peptic ulcer disease
alaRm sIgNs
   (NeeDINg fURTheR INvesTIgaTIONs)
Localized tenderness in right upper/lower quadrant
Localized fullness or mass
Hepatomegaly/Splenomegaly
Jaundice
Costovertebral angle tenderness
Arthritis
Spinal tenderness
Perianal disease
Unexplained physical findings
Pallor/Rash
Hernia
DIagNOsIs
RAP should not require an exhaustive
 series of diagnostic tests to rule out organic
 causes
History – absence of alarming symptoms
Meticulous examination
Other associated symptoms
Normal investigations
Organic & nonorganic may co-exist
INvesTIgaTIONs IN ReCURReNT
      abDOmINal paIN
Basic investigations (1st line investigations)
 Full blood count
 ESR/C-reactive protein
 Urine analysis & Urine culture
 Stool for ova, cysts and parasites
Second line investigations
 Plain X-ray abdomen
 LFT & KFT
 Celiac panel
 Abdominal ultrasound
 Breath hydrogen test for lactose intolerance
 Tests for Helicobacter pylori
 Barium follow through
 Esophageal manometry and pH-metry
 Upper and lower gastrointestinal endoscopy
 Intravenous urogram/micturition cystourethrogram
Only basic urine, stool and blood examinations are
 recommended to exclude organic causes in the
 diagnosis of RAP.
Ultrasound scanning, extensive radiographic
 evaluation and invasive investigations like endoscopy
 in these children are rarely diagnostic or cost
 effective.
Presence of an abnormal test result alone does not
 pinpoint to a diagnosis unless it is clinically relevant.
abDOmINal paIN
      TReaTmeNT
Treat organic cause if present.
For functional abdominal pain variety
 of treatments.
Close follow up required.
gUIDelINes fOR maNagemeNT
 Of ReCURReNT abDOmINal
            paIN

Rule out organic cause
Reassurance & education of the family.
Discuss the apprehensions of family.
Explore stressors.
Acknowledge but no undue attention.
Avoid psychological labelling.
gUIDelINes fOR maNagemeNT Of
     ReCURReNT abDOmINal paIN-(II)

Allow normal activity.
Establish regular follow-up system of return visits to
 monitor the symptoms.
Be available Assure parents that you are available to see
 the child if changes occur or the parents become anxious.
Allow appropriate time, in an unrushed environment for
 them.
Make judicious use of “second opinions”
DRUg TheRapIes
Pharmacological treatments are commonly used in an
 effort to manage symptoms despite the lack of data
 supporting their efficacy.
Usually a part of the multidisciplinary approach.
Commonly used medications include acid suppressants
 for dyspepsia symptoms, antispasmodics & low dose
 amitriptyline .
For chronic abdominal pain with IBS symptoms,
 antidiarrheals and nonstimulating laxatives are used.
Peppermint oil found to be very effective in the treatment
 of irritable bowel syndrome in children.
PPIs and anticholinergics are often unhelpful.
DIeTaRy mODIfICaTIONs
There is no evidence that lactose-restricted diet and
 fiber supplements decrease the frequency of attacks
 in chronic abd. pain.
In some children, there are foods, drinks, and
 medicines that make symptoms worse.
Common triggers include: High-fat foods, Caffeine &
 foods that increase gas (beans, onions, raisins,
 bananas, apricots, prunes, cabbage, cauliflower,
 broccoli etc.)
Medicines that can cause upset stomach include
 aspirin and ibuprofen etc.
behavIORal TheRapIes
Recommended for children or adolescents with functional
 abdominal pain that has severely impacted activities of
 daily living.
Cognitive-behavioral therapy is help full in short term for
 managing pain and functional disability.
Relaxation techniques, hypnosis, biofeedback, and
 psychotherapy help to reduce a child's anxiety levels, help
 them to participate in normal activities and to better
 tolerate the pain.
A significant improvement of symptoms and fewer school
 absences in children with RAP following a short period of
 cognitive behavioral family treatment is reported.
pROgNOsIs
With this approach, approximately 30% to 60% of
 children have resolution of their pain.
Remainder continue to exhibit symptoms and go
 on to be adults with abdominal pain, anxiety, or
 other somatic disorders.
Other studies have reported development of irritable
 bowel syndrome in 25-29% of them in later life.
Abdominal pain

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Abdominal pain

  • 1. RecuRRent AbdominAl PAin Dr. Ravi Malik CMD Radix Hospital IMA Headquaters DMC medical education convenor
  • 2. INTRODUCTION RAP 3 episodes over 3 months Severe enough to affect activities Inter periods of well being No specific cause identified
  • 3. epIDemIOlOgy 10-12% of school aged children. Peak incidence at 4-6 years and at 7-12 years. Obesity and RAP. Fruits consumption and RAP.
  • 4. ClINICal pROfIle Pain is genuine Peri-umbilical pain Nausea, vomiting Pallor Headache & limb pains Family history
  • 5. ClassIfICaTION • It can be organic or nonorganic. • Nonorganic(functional) abd pain • Functional dyspepsia • Irritable bowel syndrome • Abdominal migraine • Functional abdominal pain
  • 6. eTIOlOgy Organic Pain (10%) Non-organic Pain (90%) Site Flanks, suprapubic Central and often epigastric Family History - VE + VE Psychological History - VE + VE Headache - VE + VE Weight Loss +VE - VE Abnormal Signs +VE - VE Abnormal Investigations +VE - VE Alarming Symptoms + VE - VE
  • 7. Functional dyspepsia Pain or discomfort in the upper abd. Stomach fullness Bloating Nausea Retching or vomiting. Irritable bowel syndrome
  • 8. Abdominal migraine Intense abdominal pain Mid-abdomen Anorexia, nausea, vomiting, pallor, headache, or sensitivity to light A family history of migraine Functional abdominal pain syndrome
  • 9. Rap (ORgaNIC) GIT Infections – ameba, giardia, dysentry, H. pylori Inflammatory-IBD, Hepatitis, appendicitis Constipation GI reflux disease Acid peptic disease
  • 10. CaUses Of Rap Urinary tract (ORgaNIC) Gynecological Miscellaneous Urinary tract Ovarian cyst infection Abdominal Urinary calculi epilepsy Endometriosis Pelvi-ureteric Physical, junction Pelvic emotional and obstruction inflammatory sexual abuse disease Chronic pancreatitis
  • 11. paThOphysIOlOgy Gastrointestinal motility- High levels of emotional stress and abnormalities in autonomic nervous system may contribute. Visceral hypersensitivity- Intensity of signals from GIT is exaggerated. Abnormal bowel sensitivity to physiological, psychologic or noxious stimuli may be present. May occur following viral gastroenteritis or after psychologically traumatic events.
  • 12. Emotional stress Patients can sometimes date the onset of pain to a specific stressful event, such as change in school, birth of a sibling or separation of parents, family member's illess. Higher levels of anxiety and depression are found in patients with RAP than in healthy children. Starting school may also trigger recurrent abdominal pain.
  • 13. Psychological factors:- A child can develop chronic abdominal pain related to his or her need for attention. Parental response to child's pain can reinforce the child's behavior. If parents are worried about child's pain, the child may become more anxious, and the pain may worsen. Parents should pay attention to the child's other activities, this might satisfy the child's need for attention & reduce the abdominal pain.
  • 14. alaRm sympTOms (NeeDINg fURTheR INvesTIgaTIONs) Features that suggest an organic disorder may include one or more of the following:  Pain that awakens the child,  Significant vomiting/constipation/bloating  Persistent right upper/lower quadrant pain  Unexplained fever  Dysphagia  Chronic severe diarrhea  G.I. blood loss  Unintentional weight loss or slowed growth  Delayed puberty  Pain/ bleeding with urination  Family H/O inflammatory bowel disease, celiac or peptic ulcer disease
  • 15. alaRm sIgNs (NeeDINg fURTheR INvesTIgaTIONs) Localized tenderness in right upper/lower quadrant Localized fullness or mass Hepatomegaly/Splenomegaly Jaundice Costovertebral angle tenderness Arthritis Spinal tenderness Perianal disease Unexplained physical findings Pallor/Rash Hernia
  • 16. DIagNOsIs RAP should not require an exhaustive series of diagnostic tests to rule out organic causes History – absence of alarming symptoms Meticulous examination Other associated symptoms Normal investigations Organic & nonorganic may co-exist
  • 17. INvesTIgaTIONs IN ReCURReNT abDOmINal paIN Basic investigations (1st line investigations)  Full blood count  ESR/C-reactive protein  Urine analysis & Urine culture  Stool for ova, cysts and parasites Second line investigations  Plain X-ray abdomen  LFT & KFT  Celiac panel  Abdominal ultrasound  Breath hydrogen test for lactose intolerance  Tests for Helicobacter pylori  Barium follow through  Esophageal manometry and pH-metry  Upper and lower gastrointestinal endoscopy  Intravenous urogram/micturition cystourethrogram
  • 18. Only basic urine, stool and blood examinations are recommended to exclude organic causes in the diagnosis of RAP. Ultrasound scanning, extensive radiographic evaluation and invasive investigations like endoscopy in these children are rarely diagnostic or cost effective. Presence of an abnormal test result alone does not pinpoint to a diagnosis unless it is clinically relevant.
  • 19. abDOmINal paIN TReaTmeNT Treat organic cause if present. For functional abdominal pain variety of treatments. Close follow up required.
  • 20. gUIDelINes fOR maNagemeNT Of ReCURReNT abDOmINal paIN Rule out organic cause Reassurance & education of the family. Discuss the apprehensions of family. Explore stressors. Acknowledge but no undue attention. Avoid psychological labelling.
  • 21. gUIDelINes fOR maNagemeNT Of ReCURReNT abDOmINal paIN-(II) Allow normal activity. Establish regular follow-up system of return visits to monitor the symptoms. Be available Assure parents that you are available to see the child if changes occur or the parents become anxious. Allow appropriate time, in an unrushed environment for them. Make judicious use of “second opinions”
  • 22. DRUg TheRapIes Pharmacological treatments are commonly used in an effort to manage symptoms despite the lack of data supporting their efficacy. Usually a part of the multidisciplinary approach. Commonly used medications include acid suppressants for dyspepsia symptoms, antispasmodics & low dose amitriptyline . For chronic abdominal pain with IBS symptoms, antidiarrheals and nonstimulating laxatives are used. Peppermint oil found to be very effective in the treatment of irritable bowel syndrome in children. PPIs and anticholinergics are often unhelpful.
  • 23. DIeTaRy mODIfICaTIONs There is no evidence that lactose-restricted diet and fiber supplements decrease the frequency of attacks in chronic abd. pain. In some children, there are foods, drinks, and medicines that make symptoms worse. Common triggers include: High-fat foods, Caffeine & foods that increase gas (beans, onions, raisins, bananas, apricots, prunes, cabbage, cauliflower, broccoli etc.) Medicines that can cause upset stomach include aspirin and ibuprofen etc.
  • 24. behavIORal TheRapIes Recommended for children or adolescents with functional abdominal pain that has severely impacted activities of daily living. Cognitive-behavioral therapy is help full in short term for managing pain and functional disability. Relaxation techniques, hypnosis, biofeedback, and psychotherapy help to reduce a child's anxiety levels, help them to participate in normal activities and to better tolerate the pain. A significant improvement of symptoms and fewer school absences in children with RAP following a short period of cognitive behavioral family treatment is reported.
  • 25. pROgNOsIs With this approach, approximately 30% to 60% of children have resolution of their pain. Remainder continue to exhibit symptoms and go on to be adults with abdominal pain, anxiety, or other somatic disorders. Other studies have reported development of irritable bowel syndrome in 25-29% of them in later life.