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UNAIDS World AIDS Day Report | 2012
Results   1
Foreword




                             T
                                        he sun finds a way to shine into even the deepest parts of the forest.
                                        It is a metaphor for all of us who are working to restore hope and
                                        dignity around the world.

                             In the history of the AIDS response there have been, and still exist, many
                             obstacles to overcome but our path is clear—we work together to get results
                             for all people.

                             To the millions who have come together with compassion and determination,
                             on this World AIDS Day we say, your blood, sweat and tears are changing
                             the world.

                             Results are accelerating

                             There were more than 700 000 fewer new HIV infections globally in
                             2011 than in 2001. Africa has cut AIDS-related deaths by one third in the
                             past six years.

                             And as services have been scaled up, uptake has followed. In fact, what had
                             taken a decade before is now being achieved in 24 months. In the past two
                             years there has been a 60% increase in the number of people accessing
                             lifesaving treatment—8 million people are on antiretroviral therapy.

                             In most parts of the world we have seen a reduction in new HIV infections
                             among young people. We have a special message to you. We can all see by
                             the results that you already are “the change we want to see in the world”.
                             We want to know more about your aspirations and dreams. We urge you
                             to continue to engage and lead—and we are counting on you to use your
                             youth as best as you possibly can.

                             As we enter into the final years of working towards the Millennium
                             Development Goals and the United Nations Political Declaration on
                             HIV/AIDS, much remains to be done to reach our targets.




2   UNAIDS World AIDS Day Report 2012
Treatment has not yet reached 7 million people. We have three years
to eliminate all new HIV infections among children. The people who are most
affected by HIV still experience marginalization and exclusion.

The results we have seen show us that the momentum of our collective
political will and follow through can overcome the biggest of obstacles and
challenges—even the shortness of time.

It shows us that with our steadfast determination and compassion—that
invisible cord that binds us to other human beings regardless of race,
gender, personal status, religion or national borders—we can get results for
all people.




Aung San Suu Kyi                                Michel Sidibé
UNAIDS Global Advocate                          UNAIDS Executive Director
for Zero Discrimination



                                                                               Results   3
Keywords




                        Countries like South
                          Africa and India                        UNAIDS call for
                         scale up services                    the elimination of new             81 countries increase
    2012                                                       HIV infections among              domestic investments
                                                                 children in 2009                      by 50%
                             Reduction
                =           in new HIV
                             infections                           Reaching                              More
                                                                  pregnant                           investments
                                          +                        women

                                                              +                 +                +                 +
                                              Fewer
                                              deaths
                                                                                      Young
                                                                                      people                      Community
                                         Faster scale up of                         leadership                   engagement
                                          HIV treatment




4    UNAIDS World AIDS Day Report 2012
Yay!                                                                                  Gap to fill
                                                                                           by 2015
                                                                    Key populations
Results for                             HIV                           not reached
 people                              prevention                                       =
                                      services
              –                       needed
=                                –                                 Marginalization
                  Low HIV
                   testing                   –
                   uptake
                                                                   –
                                                HIV
              50% of people living
              with HIV do not know
                                             treatment
                 their HIV status             needed


                                           6.8 million people
                                        eligible and waiting for
                                               treatment




                                                                                              Results   5
At a glance

A look at the number of people living with
HIV in the world, 2011
Source: UNAIDS 2012 Global Report




                                                                             Number of AIDS-related deaths
                                                                             1.7 million
    Global overview

     34 million
     ± 50% know their HIV status




                                                                                    New HIV infections
                                                                                    2.5 million




                                         People eligible for HIV treatment
                                         14.8 million

                                                 People on HIV treatment
                                                 8 million




6    UNAIDS World AIDS Day Report 2012
Regional overview

                                                                                                North America,                   Oceania
    Asia                                                Eastern Europe         Latin America
                                                                                                Western and                      53 000
    4.8 million                                         1.4 million            1.4 million
                                                                                                Central Europe
                                                                                                2.3 million




                                                                                                                                 caribbean
                                                          Russian
                                                          Federation




                                                                                                                                 230 000
                                                          990 000


                                                                                                   United States of America
   China                                                                                           1.3 million
   780 000                                                                                                                        Middle
                            Thailand                                               Brazil                                         East
                            480 000                                                470 000                                        and
                                            Indonesia                                                                             North
                                            370 000                                                                               Africa
                                                                                                                                  300 000




    Sub-Saharan Africa
    23.5 million


                                       South Africa
                                       5.1 million                                             Uganda
     United Republic of Tanzania                                                               1.2 million
     1.3 million




     Nigeria
     3 million


                                                                                                Mozambique
                                                                                                1.2 million




                                       Zambia                          Zimbabwe
                                       800 000                         1 million                Kenya
                                                                                                1.4 million




                                       Ethiopia
                                       610 000




                                                                                                                              Results        7
Tweetable

Countries are making historic gains towards ending
 #AIDS: 700K fewer new HIV infections across the
       world in 2011 than in 2001 #Results
Sustained progress in halting
new HIV infections




               I
                  n the last ten years the landscape of national HIV epidemics has
                  changed dramatically, for the better in most countries, especially in
                  sub-Saharan Africa. Countries are making historic gains towards ending
                the AIDS epidemic: 700 000 fewer new HIV infections across the world in
                2011 than in 2001.

                Latest data show that a 50% reduction in the rate of new HIV infections
                (HIV incidence) has been achieved in 25 low- and middle-income countries
                between 2001 and 2011. More than half of these countries are in sub-
                Saharan Africa where the majority of the new HIV infections occur. In a further
                nine countries the rate of new HIV infections fell steeply—by at least one
                third between 2001 and 2011.

                The national declines in HIV incidence in populations shows that sustained
                investments and increased political leadership for the AIDS response are
                paying dividends. In particular, countries with a concurrent scale up of
                HIV prevention and treatment programmes are seeing a drop in new HIV
                infections to record lows.

                Prevention leads to behaviour change; treatment reduces a person’s viral
                load. Both reduce the potential for the virus to be transmitted. The historic
                slow-down indicates HIV prevention and treatment programmes are
                successfully reaching the people in need.

                In Southern Africa, where most countries have large numbers of people living
                with HIV or high HIV prevalence, the number of people acquiring HIV has
                been dramatically reduced. Between 2001 and 2011, in Malawi, the rate of
                new HIV infections dropped by 73%, in Botswana by 71%, in Namibia by
                68%, in Zambia by 58% and in Zimbabwe by 50%. South Africa, the country
                with the largest number of HIV infections, reduced new HIV infections by
                41%. In Swaziland, which has the highest HIV prevalence in the world, new
                HIV infections dropped by 37%.

                In West and Central Africa, Ghana was at the top of the list with a drop of 66%
                followed by Burkina Faso at 60% and Djibouti at 58%. The Central African


                                                                                                  Results   9
Republic, Gabon, Rwanda and Togo, achieved significant declines of more
                               than 50%. Other countries with significant declines in the region include
                               Burundi, Cameroon, Mali and Sierra Leone where the decline was more than
                               one third. Ethiopia achieved a 90% reduction in the rate of new HIV infections
                               in the last decade. Despite a 25% reduction in sub-Saharan Africa, the region
                               accounted for 72% of all new HIV infections worldwide in 2011.

                               The region with the sharpest declines in number of new HIV infections is the
                               Caribbean where there has been a drop of more than 42%. In Suriname, the
                               rate of new HIV infections fell by 86% and in the Dominican Republic by 73%.
                               A more than 50% decline was observed in the Bahamas, Barbados, Belize
                               and Haiti. In Jamaica and Trinidad and Tobago, new HIV infections fell by
                               more than one third. In Latin America, the number of new HIV infections has
                               remained stable.

                               In Asia and Oceania, Nepal drastically reduced new HIV infections by 91%
                               and Cambodia by 88%. Four countries that account for a large number of
                               people living with HIV in the region—India, Myanmar, Papua New Guinea
                               and Thailand—reduced new HIV infections by more than 50%. Malaysia’s new
                               infections dropped by 34%. However, the epidemic significantly increased in
                               Bangladesh, Indonesia, Philippines and Sri Lanka.




10   UNAIDS World AIDS Day Report 2012
Despite the encouraging news, national epidemics in many parts of the world
continue to expand. There is an opportunity for the redoubling of energy and
focus by these countries.

In the Middle East and North Africa, the number of people newly infected
with HIV increased by 35% between 2001 and 2011, and the rate of new HIV
infections continues to rise in Eastern Europe and Central Asia. In Georgia,
Kazakhstan, Kyrgyzstan and the Republic of Moldova the rate of new HIV
infections rose by more than 25%. In the Russian Federation the annual
number of new infections has dramatically increased in recent years, as
reflected in an increase in reported cases of new HIV diagnoses, from less
than 40 000 in 2006 to over 60 000 in 2011.

The road from 2.5 million new HIV infections—the number in 2011—to
zero new HIV infections is a long one, and there is a significant effort
required to accelerate HIV prevention programmes. But the positive
national trends for the most part compellingly indicate that with
expanded and sustained HIV prevention and treatment programmes—
that are evidence-informed and reach people at highest risk and need—
rapid declines are possible.




                                                                               Results   11
Incidence meter:
    Towards zero new HIV infections
    The rate of new HIV infections has been reduced
    by more than 50% among adults (15-49 years) in 25
    countries between 2001 and 2011

    Source: AIDSinfo




                                                                                         .18


                                  .02
                                                                          0         52%                .37
                                                                                                                                                                                         .10


                   29%                                                              Bahamas

                                                                                                                                                                               45%
             0                          .02             .10
                    Mexico                                                               .03
                                                                                                                                                                          0                                .18                      .0


                            .15               0    54%                        .22    0          73%          .09
                                                                                                                      .03                                     .12                    Mali
                                                                                                                                                                                                           0     29%
                                                                                                                           66%                    37%
                                                            Haiti                   Dominican Republic                                                                                                            Niger
                                                                               .13                                                                                             .06                                                .29

                            54
                                                                                                                                            0                         .20
                                        %                                                                    .09 0
                                                                                                                           Barbados
                                                                                                                                      .08
                                                                                                                                                Sierra Leone
                                                                33%                                                                                                            60%                                            56
                    0                             .31
                                                                                                                                                .08

                                                                                                      40
                            Belize                      0                                 .20
                                                                                                             %                                                            0                                .15         0
                                                                                                                                                                              Burkina Faso
                                                                                                                                                  66%
                                                                Jamaica                          0                   .15
                                                                                                                                                                                                                 .36       Centra
                                                                                                Trinidad and Tobago                         0                         .24                                                    Rep

                                                                                                                                                                                                       43%
                                                                                                                                                      Ghana         .23


                                                                                                      86     %
                                                                                                .02                                                                                            0                              .63


                                                                                                                                                                    57
                                                                                                                                                                                                       Cameroon
                                                                                                 0                   .11
                                                                                                                                                                              %                      .34
                                                                                                                                                                                                                                    0
                                                                                                      Suriname                                           0                                   .55
                                                                                                                                                                     Togo

                                                                                                                                                                                     0             54%                 .74
                                                                                                                                                                                                   Gabon                      0



                                                                                                                                                                                               .77



                                                                                                                                                                                         0           68%                   2.39
                                                                                                                                                                                                     Namibia
                                                                                                                                                                                                                       1.00
Percentage change in HIV
    incidence (2001-2011)
                                                                                                                                                                                                                   0          71
      HIV incidence 2001                                                                                                                                                                                                      Bots
      HIV incidence 2011


                                              86%
                              .02
                                                                                                                                                                                                                              0
                                  0                                 .11
                                                                                                                                                                                                                                    So
                                              Country




    12   UNAIDS World AIDS Day Report 2012
.01
                                                                                                        0     91%              .09
                                                                                                                Nepal
                                          .11
08                                                                                                                            .03


     .11                      0       58%                     .27
                                                                                                        .02
                                                                                                                          0          74%              .10
                                                                                                                                     Myanmar
                                                                                                       57%
                                          Djibouti
                                                                                                  0                     .04

                                                                                                                                                            88%
                                                                                                                                                .01

6     %                                                                                                     India

                                          90      %
                                                                                                                                      .03        0                     .07
                   .67       .03
                               0                              .29                                                                                           Cambodia
al African                                                                            .45
public
           .15
                                          Ethiopia
                                                                                                                                    53%                                      .04

                                                                            32     %                                      0                           .05
                                                        .04
                                                                 0                          .66                                      Thailand

           53%                                                                Kenya                                                                              34%                          .04

                                                 49
                                                                                                                                                             0                     .05
0
           Rwanda
                                    .31
                                      0
                                                          %           .09                                                                                        Malaysia
     .08
                                                 Burundi
                                                                                                                                                                                         0   53%              .09


    58%
                                          .49
                                                                                                                                                                                         Papua New Guinea

     Zambia
                 1.05
                             1.89
                                      0          72%                  1.74
                                                 Malawi


            50%
                                                                     1.13
     0                                    2.11
            Zimbabwe
                                            0      31%                      1.63
                                                 Mozambique

1%               3.49
                                                 2.60


 wana
            1.43
                         0          37%                   4.11
                                   Swaziland

    41%                      2.42
 outh Africa




                                                                                                                                                                                                    Results    13
What keeps me going is the knowledge that ARVs are affordable and
available…The number of people I know who have HIV and are living a
       normal life, even starting families, really keeps me going.

                    Person living with HIV, Uganda
Record access to HIV treatment,
record drop in AIDS-related deaths




               T
                        he latest data gathered from countries around the world tell a story of
                        clear success. Sustained investments in access to antiretroviral therapy
                        by donors and national governments have led to record numbers of
               lives being saved in the past six years. In 2011 more than half a million fewer
               people died from AIDS-related illnesses than six years earlier. It’s a dramatic
               turning point. In 14 countries, AIDS-related deaths dropped by more than
               50% between 2005 and 2011. Numbers can quantify, but alone cannot
               express the impact of each averted death on the whole community, including
               its children.

               For the first time, a majority of people eligible for HIV treatment in low-
               and middle-income countries—54%, a record eight million people—were
               receiving antiretroviral therapy. This means more people than ever who are
               living with HIV are being helped to live longer, healthier and more productive
               lives. Lessons learned through the past decade have led to improved
               collaboration between governments, donors, partners, and a combination of
               innovation, efficiency and increased domestic investments have seen a return
               on investment unparalleled in the AIDS response.

               The part of the world most impacted by HIV, sub-Saharan Africa, has cut the
               number of people dying of AIDS-related causes by 32% between 2005 and
               2011. The largest drop in AIDS-related deaths was in some of those countries
               where HIV has the strongest grip. In South Africa, 100 000 fewer deaths
               occurred, followed by nearly 90 000 in Zimbabwe, 71 000 in Kenya, 59 000 in
               Ethiopia and 48 000 in the United Republic of Tanzania.

               A number of the region’s countries with smaller populations but high HIV
               prevalence have also made significant gains in averting deaths related to
               AIDS. Botswana cut AIDS-related deaths by 71%, Rwanda by 68%, Namibia
               by 60%, Zambia by 56% and Burundi and Côte d’Ivoire by 51%. Benin,
               Burkina Faso, Eritrea, Guniea, Lesotho, Malawi and Mali all reduced AIDS-
               related deaths by one third.

               The countries of the Caribbean experienced a 48% decline in AIDS-related
               deaths while in Oceania the drop was 41%. The Dominican Republic had


                                                                                                   Results   15
Declines in TB-related AIDS deaths among
people living with HIV, 2005-2011
Source: Global Tuberculosis Report 2012. Geneva, World Health
Organization, 2012: www.who.int/tb/publications/global_report/en                                 Global estimate
                                                                                                 Africa estimate
                                        600 000
     Number of TB-related AIDS deaths




                                                                                       9%
       among people living with HIV




                                        500 000
                                                                                                             13%
                                                                                       10%
                                        400 000
                                                                                                             15%
                                        300 000
                                                                   Four years                    24 months
                                        200 000

                                        100 000

                                             0
                                                  2005      2006     2007       2008     2009      2010        2011



                                                         61% fewer people dying from AIDS-related causes while Guyana, Haiti,
                                                         Jamaica and Suriname saw a more than 40% reduction.

                                                         In Asia, Cambodia reduced its AIDS-related deaths by 77% and Thailand
                                                         by 49%. Peru reduced AIDS-related deaths by 55% and Mexico by 27%.
                                                         Countries like Argentina, Brazil, Chile, Ecuador, El Salvador, Nicaragua,
                                                         Paraguay and Venezuela provided access to drugs to between 60% and 79%
                                                         of people eligible for HIV treatment.

                                                         Worrisome increases in AIDS-related mortality were observed in Eastern
                                                         Europe and Central Asia (21%) and the Middle East and North Africa (17%).
                                                         However, Djibouti showed a decline of 26% in AIDS-related deaths.

                                                         Impressive gains were also made in cutting deaths from tuberculosis (TB) in
                                                         people living with HIV. Between 2004 and 2011, TB-related AIDS deaths fell
                                                         by 25% worldwide and by 28% in sub-Saharan Africa. In the last 24 months, a
                                                         13% decrease in TB-related AIDS deaths was observed in 2011, compared to
                                                         a 10% decrease over the four-year period between 2004 and 2008.

                                                         This accomplishment is due to record numbers of people with HIV/TB co-
                                                         infection accessing antiretroviral treatment—a 45% increase between 2009
                                                         and 2011. India, Kenya, South Africa, Zambia and Zimbabwe accounted
                                                         for two thirds of all new people with HIV/TB co-infection being treated, but
                                                         much more needs to be done. No-one should die of TB and HIV.


                                                         How have lives been saved?

                                                         In just the past two years, HIV treatment access grew by 63% around
                                                         the world. The massive scale up over the last 24 months enabled tens of
                                                         thousands of people living with HIV to receive lifesaving antiretroviral therapy
                                                         for the first time. The increase came at a time when international funding for
                                                         AIDS remained flat. Countries are better implementing programmes. They
                                                         have used a combination of innovation, efficiency and increased domestic
                                                         investments to sustain the rapid growth in access to treatment. The price of


16                UNAIDS World AIDS Day Report 2012
antiretroviral drugs has reduced dramatically from US$ 10 000 per person a
decade ago to around US$ 100 annually in some countries.

In sub-Saharan Africa, a record 2.3 million people were added to treatment
programmes in the last two years—an increase of 59%. South Africa scaled
up its treatment services to reach 1.7 million people—an increase of 75% in
the last two years. In Zimbabwe, 260 000 additional people accessed HIV
treatment, registering a 118% expansion rate. In Kenya, 200 000 people
were added—a 59% increase. Upwards of 100 000 people living with HIV
were enrolled in HIV treatment in Malawi, Mozambique, Nigeria, Uganda
and Zambia each. Five countries in the region have achieved more than 80%
coverage of HIV treatment—Botswana, Namibia, Rwanda, Swaziland and
Zambia. Outside of sub-Saharan Africa, China has increased the number of
people on HIV treatment by nearly 50% in the last year alone.

Since 1995, antiretroviral therapy has saved 14 million life years in low- and
middle-income countries, including nine million in sub-Saharan Africa. Fewer
deaths from AIDS-related illnesses has transformed societies: more people,
regaining their health, are returning to work and taking care of their families.

However, the gap between people who can access treatment and people
in need is still very large, nearly 46%, and as the demand for treatment
as prevention continues to rise and increasingly outstrips availability, this
treatment gap is set to grow.




                                                                                   Results   17
Showing impact:
HIV treatment saves lives

The number of people dying from AIDS-related causes
began to decline in the mid-2000s because of scaled
up antiretroviral therapy and the steady decline in HIV
incidence since the peak of the epidemic in 1997.

In 2011, this decline continued, with evidence showing that
the drop in the number of people dying from AIDS-related
causes is accelerating in several countries.

                                                                                                                                                                   673      413
Source: UNAIDS 2012 Global Report

                                                                                                                                                                   39
                                                                                                                                                                   Germany
                                                                                                                                                                            %


                                                                                                                                                                                    18


                                                                                                                                                                                28  Cro


                                                      508       373


                                                     27
                                                      Bahamas
                                                                %
                                                                                                                                                                                         1
                                                                                                                                       9,925     6,553
                  6,678


                   27
                          4,862

                          %                        % 61
                                                              10,884      5,825
                                                                                   4,323         1,696

                                                                                                 %                                      34%
                                            49% 46
                                           3,208      1,646
                                                                                                                                              Mali
                                                                                                                            6,157      4,028                               14,982        1
                    Mexico
                                                                   Haiti Dominican Republic
                                                                                                                                                                             31%
                                                                                                                                                12,717    6,758
                                             Jamaica
                                                                                                         36    26            35%                     47%
                                                                                                         28%                  Guinea                                     Central Af
                                                                                                                                                Burkina Faso
                                                                                                                                                                           Republ
                                                                                                         Barbados
                                                                                                                                                         5,451     2,759


                                                                                                                                                          49       %
                                                                                                                    3,353    2,331


                                                                                                                     30% 51%
                                                                                                                                     46,684     22,800

                                                                               600         243
                                                                                                                                                             Benin
                                                                               60          %
                                                                                                 675     294
                                                                                                                       Liberia
                                                                                                                                     Côte d’Ivoire                 6,614      4,630
                                                                                  Guyana
                                                                                             56%
                                                                                                                                                21,803    15,337
                                                                                                                                                                    30        %
                                                                                                 Suriname                                            30
                                                                                                                                                     Ghana
                                                                                                                                                          %           Congo
                                                                                                                                                                             70,685


                                                                                                                                                                                  56
                                                    6,722       3,029


                                                     55%               2,196      1,592
                                                                                                                                                                                    Zam
                                                        Peru
                                                                        28Bolivia
                                                                                  %
                                                                                      399         299                                                              12,825      5,184


                                                                                      25
                                                                                      Paraguay
                                                                                                  %                                                                  60        %
                                                                                                                                                                         Namibia
AIDS-related deaths in 2005                                                                                                                                                   370,874
AIDS-related deaths in 2011

                                    46,684         22,800                                                                                                                      South
                                                                                                                                                                                    27
     Percentage of decline in
        AIDS-related deaths
                                       51% Country
                (2005 - 2011)




18     UNAIDS World AIDS Day Report 2012
13


8%
oatia




15,967       12,034


  25%                          2,121          1,402

     Chad
10,278
                                34%
                                  Eritrea
                                                                     45,146   23,147


%                                              1,184     880
                                                                       49     %
                                                26
            113,825          53,831
                                                         %
                   53%
                                                                        Thailand
frican
lic                                              Djibouti                      6,232   1,449


                                                                                77
                   Ethiopia
                                                                                       %
                                                                                Cambodia
 19,788           6,353    133,503           61,691


   68         %                54         %                                                      2,113   1,134

    Rwanda                       Kenya         131,704      83,528
                                                                                                  46%
              11,904


                   51
                             5,787

                             %                    37%
                                             United Republic
                                                                                               Papua New Guinea

   31,282                                      of Tanzania
                    Burundi
6%
mbia
   14,542          4,208       76,589         43,858


        71
     Botswana
                   %             43Malawi
                                              %

                   147,876       58,339



    270,190
                      61%
                      Zimbabwe
7   %
h Africa
                                     9,914       6,813
         21,714       13,986
                                       31        %
           36%
            Lesotho
                                      Swaziland




                                                                                                     Results     19
Tweetable

The aspiration that the world can fully fund the
AIDS response is achievable w/ continued shared
   responsibility & global solidarity #Results
Global solidarity and shared
responsibility is sustaining
investments in AIDS




               L
                     ow- and middle-income countries are driving the global increase
                     in HIV investments. The global gap in resources needed by 2015 has
                     now dropped to about 30%. The aspiration that the world can fully
                fund the AIDS response is achievable with continued shared responsibility
                and global solidarity.

                For the first time ever, domestic investments have surpassed global giving
                for AIDS, tipping the aid dependency balance. Domestic investments rose
                from US$ 3.9 billion in 2005 to almost US$ 8.6 billion in 2011. Some 81
                countries increased domestic investments for the AIDS response by more
                than 50% between 2006 and 2011. However, international investments still
                remain critical and indispensable.

                Increased country ownership for domestic investments

                South Africa is the country that has made the highest domestic investment in
                AIDS among all low- and middle-income countries. It alone invested US$ 1.9
                billion last year from public sources, resulting in a five-fold increase between
                2006 and 2011. This strategic leadership is an example being echoed across
                the region. Kenya doubled its domestic investments for AIDS between 2008
                and 2010, and Togo did the same between 2007 and 2010. This year, Zambia
                has put a massive injection of funds into its health budget, increasing it by
                45%.

                Many middle-income countries are increasingly taking responsibility for
                funding the majority of their AIDS response needs.

                Exceptional leadership is coming from the world’s fastest-growing
                emerging economies: Brazil, Russia, India, China and South Africa (BRICS).
                Together, they contribute to more than half of all domestic spending on
                AIDS in low- and middle-income countries. Their momentum is unparalleled,
                having increased domestic public spending by more than 122% between
                2006 and 2011.

                Brazil and Russia fund almost all of their national AIDS responses from
                domestic sources. Brazil has for years invested adequately and focussed on


                                                                                                   Results   21
the most vulnerable and marginalized and reaped benefits. Russia on the
                              other hand has not realised the same value for money as its AIDS investment
                              strategy is not optimized to its epidemic patterns. China currently invests more
                              than 80% domestically, and the country has announced it will fully fund its AIDS
                              response in the coming years. India, too, has committed to increase domestic
                              funding to more than 90% in its next phase of the AIDS response. These fast-
                              growing economies have the potential to support others in the region, as
                              well as exert leadership and influence on the AIDS response, both locally and
                              globally.

                              International investments—fragile status quo

                              Against the backdrop of continued economic uncertainties in high-income
                              countries, international investments have remained stable at around US$ 8.2
                              billion in 2011, although the economic downturn has impacted development
                              assistance budgets. The healthy growth in domestic investments is most
                              welcome, and it has indeed become critical to service delivery. However,
                              international assistance remains a crucial lifeline for many countries with low
                              income and high HIV prevalence that have little fiscal space to absorb cuts in
                              development aid. In 26 of 33 countries in sub-Saharan Africa, donor support
                              accounts for more than half of the current AIDS response investments in the
                              region.

                              The lion’s share of international assistance is directed towards supporting
                              HIV treatment, in particular in high burden countries in sub-Saharan Africa.
                              This could render gains in coverage of lifesaving treatments fragile should
                              international assistance drop in the coming years. It is heartening to note
                              many high-income countries have maintained their current levels of funding,
                              in spite of the persistent fragility of their economies. The United States of
                              America continues to be the largest international donor—both bilaterally
                              and through multilateral funding channels—accounting for 48% of all such
                              assistance. As economies recover, international investments must increase,
                              and the donor base has to become more diversified and include the
                              increasing capabilities of emerging economy countries.



22   UNAIDS World AIDS Day Report 2012
Making strategic use of AIDS investments

An important strategy for enhancing value for money is to maximize impact
and cost-efficiency by focusing limited resources where the epidemic is most
severe and on the populations in the greatest need—the spending pattern
differs between regions and countries according to their type of epidemic. In
some settings, investing more strategically requires focusing a larger share of
prevention spending on the general population. In other countries, the focus
needs to be on the key populations that represent the largest percentage of
people newly infected. It is estimated that by 2015 the share of investment
needs for basic prevention programmes, such as male circumcision,
preventing mother-to-child transmission and key populations at higher risk,
will have to be increased. For example, today, programmes to reach key
populations receive only 4% of investments globally, but for an optimized HIV
response in 2015, this share will need to be about 14%.

Closing the resource gap

Multiple avenues will need to be pursued if the world is to reach the target of
mobilizing US$ 22-24 billion annually for the response. Countries should ensure
that HIV spending is focused on effective investments and take steps to further
increase their domestic spending for the AIDS response, including developing
innovative and sustainable AIDS funding sources. Efforts must be intensified
to improve the efficiency of AIDS spending through such means as capturing
productivity gains, continuing to reduce the price of antiretroviral medicines,
integrating services and improving service delivery. Economic growth in
low- and middle-income countries can help expand the fiscal space for HIV
investment, and further efforts are needed to cultivate emerging economies as
international AIDS donors. In the context of shared responsibility and global
solidarity, current international donors must also remain engaged in closing the
resource gap for countries in need. Only by applying the investment approach
and working within a framework of shared responsibility will countries reach
their 2015 goal.




                                                                                   Results   23
A smaller funding gap to close

There is increasing country ownership and shared responsibility for investments in the AIDS response.
Domestic investments now account for the majority of AIDS investments. The gap for investment needs
in 2015 is closing, but much more can be done to make investments effective and efficient.




Resources available for HIV in
low- and middle- income countries, 2007-2011
Source: UNAIDS 2012 Global Report




                                                           2011

                                                           2010

                                                           2009

                                                           2008

                                                           2007
                                               43%

                                                     42%
                                         44%
                                 50%
                          51%




                                                                      58%




                                                                                        50%
                                                                                  56%
                                                                            57%




                                                                                              49%
         Domestic                                                                                   International




                 International investment
                 Domestic investment




24   UNAIDS World AIDS Day Report 2012
Resources needed for HIV in low-
and middle-income countries in 2015
Source: UNAIDS 2012 Global Report


                                                        Need in 2015
                                                      US$ 24 billion




                                                 Current HIV investments
                                                     US$ 16.8 billion




       Key populations at
           higher risk
        US$ 1.7 billion                                                                  Male circumcision

        US$ 228 million                                                                  US$ 134.5 million
                                                                                         US$ 26.5 million



                                                Investments for basic HIV
                                                prevention and treatment                 Condom promotion
                                                      programmes
                                                                                           US$ 300 million
                                                     US$ 10.7 billion
                                                                                           US$ 110 million
                                                     US$ 5.7 billion


                                                                            Behavioural Change
                                                                             US$ 625 million
                                                                             US$   70 million



                  Treatment, care and support
                          US$ 6.8 billion
                                                Prevention of mother-
                          US$ 5.1 billion       to-child transmission
                                                  US$     1.1 billion              Investment needs in 2015
                                                  US$ 201 million                  Current investments




                                                                                                             Results   25
Having been born with HIV, I have always lived with the virus.
Today it represents taking a couple of pills two times each day…
       and it doesn’t have to be anything more than that.

                     Alejandro, Argentina
Declining new HIV infections in
children and young people




                Rapid declines in new HIV infections among children



               N
                        ew HIV infections in children dropped by 43% from 2003 to 2011.
                        In fact, new HIV infections in children declined by 24% in the last
                        two years alone, which is much sharper than the 19% drop seen in
                the four year period between 2004 and 2008. Half of all new HIV infections
                averted—in adults and children—in the 24-month period between 2009 and
                2011 were among newborn children. This reduction has been accelerated by
                the rapid progress made in the last two years in giving more women living
                with HIV access to prevention and treatment services.

                When women living with HIV receive antiretroviral prophylaxis during
                pregnancy, delivery and breastfeeding, the risk of HIV transmission is reduced
                to less than 5%.This accelerated progress in cutting new HIV infections
                has happened as countries move forward in implementing the Global Plan
                towards the elimination of new HIV infections among children by 2015 and
                keeping their mothers alive.

                However, acute geographic inequalities continue. Of the children who
                acquired HIV in 2011, close to zero live in high-income countries and more
                than 90% live in sub-Saharan Africa. Encouragingly, the number of children
                newly infected in the region fell by 24% from 2009 to 2011. Countries with
                generalized epidemics have the overwhelming majority of children newly
                infected and they have made major gains during the past decade. In six
                countries—Burundi, Kenya, Namibia, South Africa, Togo and Zambia—the
                number of children newly infected fell by between 40% and 59% from 2009
                to 2011. In 16 additional countries, declines of between 20% and 39%
                occurred during the same period.

                The number of children acquiring HIV infection has declined significantly
                in the Caribbean (32%) and Oceania (36%), with a more modest decline in
                Asia (12%). New infections also dropped in Latin America (24%) and Eastern
                Europe and Central Asia (13%), regions that had already significantly reduced
                the numbers of children newly acquiring HIV infection. The Middle East and



                                                                                                 Results   27
New HIV infections among children
(0-14 years old) 2003-2011
Source: UNAIDS 2012 Global Report


                                           600 000
       Number of children newly infected




                                                                                                           23%
                                           500 000

                                           400 000                                                                                  24%
                  with HIV




                                           300 000
                                                                                       Six years                        24 months
                                           200 000

                                           100 000

                                                0
                                                     2003   2004      2005      2006       2007     2008         2009     2010      2011



                                                      North Africa is the only region that has yet to see a reduction in the number
                                                      of children newly infected.


                                                      Reaching pregnant women living with HIV

                                                      Although reductions in the number of adults acquiring HIV infection are
                                                      helping to lower children’s risk of HIV, recent gains in bringing antiretroviral
                                                      and infant feeding–based prevention services to scale are primarily
                                                      responsible for the sharp reductions in the number of children newly infected.
                                                      From 2009 to 2011, antiretroviral prophylaxis prevented 409 000 children
                                                      from acquiring HIV infection in low- and middle-income countries.

                                                      In low- and middle-income countries, coverage of effective antiretroviral
                                                      regimens for preventing mother-to-child transmission reached 57% in 2011.
                                                      Apart from high-income countries, which have long had near-universal
                                                      coverage for antiretroviral medicines for pregnant women, the Caribbean is
                                                      the only region approaching similarly high coverage levels at 79%.

                                                      In sub-Saharan Africa, the region where 92% of the world’s HIV-positive
                                                      pregnant women live, 59% of them received antiretroviral therapy
                                                      or prophylaxis during pregnancy and delivery in 2011.

                                                      Ensuring a mother living with HIV has access to HIV treatment not only has
                                                      health benefits for her, but also for her family. Studies indicate that children
                                                      whose mothers stay alive and healthy have a decreased risk of death
                                                      regardless of the child’s HIV status. Recent estimates suggest that pregnancy-
                                                      related deaths among women living with HIV have declined from 46 000 in
                                                      2005 to an estimated 37 000 in 2010. More effort is needed to ensure that
                                                      pregnant women tested for HIV during antenatal care are also tested for
                                                      eligibility for antiretroviral therapy.




28   UNAIDS World AIDS Day Report 2012
Young people—bringing change, shaping the future

The actions of young people are shaping the future of AIDS across the world.
Between 2001 and 2011, prevalence of HIV—a proxy indicator of new HIV
infections—fell by nearly 27% among young people aged 15-24 globally. The
largest progress was seen in South and South-East Asia where HIV prevalence
among young men and women fell by 50%. Sub-Saharan Africa and the
Caribbean followed with a drop of more than 35% among young men and
women. In Latin America, HIV prevalence decreased by nearly 20% among
young people. Significantly, the decline was much higher at 33% among
young men, the group where the majority of new HIV infections among young
people in Latin America occur.

This encouraging trend is reversed in Eastern Europe and Central Asia where
there has been a 20% increase in new HIV infections among young people.
The majority of young people who are acquiring HIV are those who inject
drugs, very few of whom have access to evidence-informed HIV prevention
and treatment services.

Today, young people account for 40% of all new adult HIV infections. Each
day, more than 2400 young people become infected with HIV—and some five
million young people are living with HIV. Young people are a fulcrum. They
remain at the centre of the epidemic and they have the power, through their
leadership, to definitively change the course of the AIDS epidemic. Today,
they are already doing so.




                                                                               Results   29
Global plan progress

Much progress has been made in stopping new HIV infections among children in the 21 countries covered by
the Global Plan towards the elimination of new HIV infections among children by 2015 and keeping their mothers
alive. This chart provides a snapshot of progress made against three select indicators—1) the number of children
acquiring HIV infections from mother-to-child HIV transmission; 2) the percentage of women receiving antiretroviral
drugs (excluding single dose nevirapine) to reduce transmission during pregnancy and 3) the percentage of
pregnant women living with HIV eligible for HIV treatment receiving antiretroviral therapy.


Source: A progress report on the Global Plan, 2012. UNAIDS




                                  5300                                                500                                                        1900



                    0
                    0           16 %                  5300
                                                      100
                                                                   0
                                                                   0                93 %                  700
                                                                                                          100
                                                                                                                                 0
                                                                                                                                 0              38 %             2700
                                                                                                                                                                 100



                                     0%                                               77%                                                        0%


                               Angola                                              Botswana                                                 Burundi


                                  13000                                              2700                                                        13200




                    0
                    0           24 %                  18900
                                                      100
                                                                   0
                                                                   0                75 %                  3900
                                                                                                          100
                                                                                                                                 0
                                                                                                                                 0              67%              23200
                                                                                                                                                                 100
                        24%


                                                                                      0%                                                         61%


                              Ethiopia                                              Ghana                                                       Kenya


                                                                                     69300
                                            800                                                                                                          29100


                   0
                   0            85 %                  1900
                                                      100
                                                                   0
                                                                   0                18 %                  70900
                                                                                                          100
                                                                                                                                 0
                                                                                                                                 0
                                                                                                                                            >   95%              56500
                                                                                                                                                                 100
                                                                             27%

                               84%                                                                                                         69%



                              Namibia                                              Nigeria                                              South Africa




     Number of new HIV infections among children, 2011                 500

                                            2015 target
                        Percentage of women receiving
                                                                   93 %
                                                              0                            700            Number of new HIV infections among children, 2009
                    antiretroviral therapy to reduce HIV
                         transmission during pregnancy        0                            100



                                                                    77%                          Percentage of pregnant women living with HIV
                                                                                                 receiving antiretroviral therapy

                                                                  Country



30   UNAIDS World AIDS Day Report 2012
6800                       4800                                 4400



0
0           54 %       8900
                       100
                              0
                              0
                                  19%
                                          13 %            5000
                                                          100
                                                                     0
                                                                     0          68 %           5400
                                                                                               100
    28%


                                                                                 0%


      Cameroon                            Chad                            Côte d’Ivoire


                3700                       15700                                27100



0
0           63 %       4700
                       100
                              0
                              0           53 %            21300
                                                          100
                                                                     0
                                                                     0          51%            28400
                                                                                               100
                                                                         25%
     45%
                                    51%




           Lesotho                        Malawi                          Mozambique


                1200                       20600                                21900



0
0           95 %       2000
                       100
                              0
                              0   15%
                                          50 %            27300
                                                          100
                                                                     0
                                                                     0          74 %           26900
                                                                                               100

                                                                         40%
          71%



          Swaziland                     Uganda                    United Republic of Tanzania



                                                                                        9700
                                                   9500


                              0
                              0           85 %            21000
                                                          100
                                                                     0
                                                                     0          78 %           17700
                                                                                               100

                                                                          51%
                                          88%


                                        Zambia                             Zimbabwe




                                                                                                       Results   31
I have learned to rise above stigma by standing up for
what I believe in. I speak of universal access to comprehensive health
    care for all—without any form of stigma and discrimination.

                          Michael, Nigeria
The miles we need to go in 1000 days




               A
                       mere thousand days remain before the world has to achieve
                       its 2015 global AIDS targets—reduce sexual transmission
                       of HIV and new HIV infections among people who inject
               drugs by 50%, eliminate new HIV infections among children, provide
               antiretroviral treatment to 15 million people and reduce TB-related
               AIDS deaths by 50%. To enable this to happen, nations committed to
               investing up to US$ 24 billion annually by 2015.

               The destination is clear. Strides forward have to be long, steady
               and purposeful.

               Multiplying the power of HIV treatment

               Antiretroviral therapy has emerged as a powerful force for saving lives. Yet
               despite the unprecedented growth in numbers of people on HIV treatment
               in the last two years, nearly half of all who are eligible (having a CD4 count
               of less than 350 per ml, the current threshold) do not have access—that’s
               6.8 million people in 2011. Half will die within 24 months if they don’t start
               antiretroviral therapy. The number eligible will rise as more of the 34 million
               people living with HIV become eligible for treatment for their own health.

               UNAIDS estimates that an additional four million discordant couples (where
               one partner is living with HIV) would benefit from access to antiretroviral
               therapy to protect their partners from HIV. Using antiretroviral therapy
               as a prophylaxis for people at high risk of HIV infection is also gaining
               momentum.

               HIV treatment is for life and people living with HIV need to take pills every
               day without fail. There is an urgent need to improve retention rates for
               people enrolled in HIV treatment as studies show that adherence can
               fall as people regain good health. Nearly half of the people who began
               antiretroviral therapy at a treatment centre in Malawi are no longer in care
               five years later and this proportion is nearly 40% in centres in Kenya. Where
               communities actively engage in providing care, retention rates are steady.
               Two-year retention rates in Mozambique climbed to 98% in a programme


                                                                                                 Results   33
where community support strategies were introduced to complement
                              clinical services.

                              Though treatment prices continue to plummet, second and third line treatment
                              regimens are still very expensive and many countries experience human resource
                              constraints for delivery. Both programme management costs and drug prices can
                              and will have to fall significantly to contain the treatment bottom line.

                              A number of strategies would help. Programmes can better leverage
                              opportunities to link treatment to other services like couples counselling and
                              testing or opioid substitution therapy. A shift from international to domestic
                              production of drugs and a strong vigilance on trade agreements could spread the
                              risks to sustained delivery of lifesaving medicines in the medium and long-term.

                              Despite considerable increases in domestic funding, countries continue to rely
                              on overseas development assistance for their HIV response. International funding
                              accounted for more than half of spending in 59 countries and contributed more
                              than 75% of spending in 43 of the 102 low- and middle-income countries.

                              Knowing your HIV status

                              Increases in access to treatment can be partly attributed to a growing number
                              of people living with HIV knowing their HIV status. In Ethiopia an estimated 21%
                              of adult men were tested for HIV in 2011 up from approximately 2% in 2005. In
                              Rwanda nearly 39% of adult women were tested for HIV in 2010 compared to
                              about 12% in 2005. In Lesotho an estimated 42% of adult women reported that
                              they had been tested for HIV in 2009 compared to about 6% in 2004. Surveys in
                              14 countries in sub-Saharan Africa between 2004 and 2011 found significantly
                              more adults had taken an HIV test in the previous year. Multi-disease prevention
                              campaigns in Kenya and Uganda show the potential of innovative community-
                              based HIV testing and counselling approaches. In Kenya around 23% of adult
                              men were tested for HIV between 2008 and 2009 compared to 8% in 2003.

                              Although the trend towards increased population-based testing rates is
                              encouraging, the available evidence does not conclusively show that HIV testing
                              programmes are reaching the people at highest risk. At the end of 2011 it is
                              estimated that only half of all people living with HIV know their HIV status.

                              Reaching children and pregnant women living with HIV

                              While much progress has been made in sub-Saharan Africa in increasing services
                              to prevent mother-to-child transmission of HIV, reported coverage is substantially
                              lower in South and South-East Asia (18%) and in the Middle East and North Africa
                              (7%). It is also difficult to estimate service needs and coverage among women at
                              highest risk of HIV in countries with concentrated epidemics.




34   UNAIDS World AIDS Day Report 2012
The percentage of treatment-eligible pregnant women living with HIV who are
receiving antiretroviral therapy was 30% in 2011—lower than the estimated 54%
coverage for all adults eligible according to WHO guidelines. Qualitative research
is needed to determine why despite improving access to health care, pregnant
women are not starting, or being reported to start, antiretroviral therapy.

While the drop in new adult HIV infections is helping to lower children’s risk
of acquiring HIV, the recent growth of antiretroviral- and infant feeding-based
prevention services are primarily responsible for the sharp reductions in the
number of children newly infected. From 2009 to 2011, antiretroviral prophylaxis
prevented 409 000 children from acquiring HIV infection in low- and middle-
income countries. Greater efforts are required to stop primary HIV infection
among women and provide reproductive and sexual health services for women
living with HIV who do not want to get pregnant. At the same time there are
disturbing reports of forced sterilization of women living with HIV in many parts
of the world—acts which are a violation of human rights and a gross abuse of
authority and trust.

Bringing combination HIV prevention programmes to scale

There were 2.7 million new HIV infections among adults and children in
2011—a long way from the vision of getting to zero. Despite impressive gains,
sub-Saharan Africa accounted for 72% of all new HIV infections and new HIV
infections are rising in Eastern Europe and Central Asia. HIV prevention gains can
be accelerated if all the current HIV prevention options are made available to
people at risk in a smart and efficient manner.

Male circumcision: Scaling up voluntary medical male circumcision has the
potential to prevent an estimated one in five new HIV infections in Eastern
and Southern Africa by 2025. The unit cost is relatively low and is a one-time
rather than lifelong expenditure. Nevertheless, countries allocate relatively few
resources towards this service—less than 2% of total HIV expenditure in six of the
14 priority countries where data is available.

In Kenya nearly 54% of adults in the Nyanza province have been circumcised
and more than 20% in Ethiopia and Swaziland. But in six countries—Malawi,
Mozambique, Namibia, Rwanda, Uganda and Zimbabwe—less than 5% of the
target number of men had been voluntarily circumcised by end of 2011.

Changing sexual behaviour to avert HIV: Sexual behaviour among men and
women has changed to become safer in numerous countries with generalized
epidemics including Kenya, Malawi, Mozambique, Namibia, Nigeria and Zambia.
In other countries—such as Côte d’Ivoire, Guyana and Rwanda—sexual risk
behaviour is increasing, highlighting the need to intensify support for behaviour
change efforts.




                                                                                 Results   35
Age-appropriate sexuality education may increase knowledge and contribute
                               to more responsible sexual behaviour however there are gaps in even
                               basic knowledge about HIV and its transmission. In 26 of 31 countries with
                               generalized epidemics in which nationally representative surveys were
                               recently carried out, less than 50% of young women have comprehensive and
                               correct knowledge about HIV.

                               Although population-level behaviour change has been shown to reduce the
                               prevalence of HIV infection in several countries with generalized epidemics,
                               linking behaviour change programming to specific HIV outcomes remains
                               challenging.

                               Increasing consistent, correct, condom use: Condom use is a critical
                               element of combination HIV prevention and one of the most efficient
                               technologies available to reduce the sexual transmission of HIV. Although
                               levels of reported condom use appear to be increasing in several countries
                               with a high HIV prevalence, recent data from nationally representative surveys
                               indicate declines in Benin, Burkina Faso, Côte d’Ivoire and Uganda.

                               The United Nations Population Fund (UNFPA) estimates that only nine donor-
                               provided male condoms were available for every man aged 15–49 years in
                               sub-Saharan Africa in 2011 and one female condom for every 10 women
                               aged 15–49 years in the region. Less is known about the condoms directly
                               procured by low- and middle-income countries. One estimate suggests more
                               than two billion condoms were directly procured in 2010, far short of the 13
                               billion estimated for HIV prevention in 2015.

                               Reaching populations at highest risk: HIV continues to have a
                               disproportionate impact on sex workers, men who have sex with men and
                               people who inject drugs. A recent review of data in 50 countries showed that
                               12% of female sex workers are living with HIV and the chance of women who
                               engage in sex work being infected is 13.5 times higher than others. Often
                               countries with generalized epidemics—where more than one in 100 adults
                               have HIV—fail to recognize the severity of burden faced by sex workers,
                               nearly one in four of whom in their capital cities are living with HIV.

                               Similar trends are seen among men who have sex with men. Go to any capital
                               city in the world, men who have sex with men are significantly more likely to
                               have HIV—on average 13 times more than the general population. As global
                               HIV prevalence trends appear to have stabilized there is disturbing evidence
                               suggesting that global HIV prevalence among men who have sex with men
                               may have increased between 2010 and 2012.

                               People who inject drugs are the worst off: evidence from 49 countries shows
                               that their risk of being infected with HIV is 22 times higher than the general
                               population. In 11 countries the chances are 50 fold higher.



36   UNAIDS World AIDS Day Report 2012
In countries of Eastern Europe up to 40% of new HIV infections occur among
people who inject drugs and their sexual partners. In Armenia, in addition to drug
use, nearly a quarter of new infections occur among men who have sex with men.

Popular opinion in countries with generalized epidemics is that HIV infection
is found evenly across the adult population. Evidence points otherwise. For
example, modelling studies conducted in Kenya show that 33 out of every 100
new HIV infections occur among sex workers, their clients, people who inject
drugs, men who have sex with men and people in prisons.

About two thirds of countries report having risk reduction programmes for sex
workers. New data from surveys conducted in capital cities of 58 countries
suggest that median coverage of HIV prevention services is 56%, up very slightly
from 2010. Coverage is lower in countries lacking legal protection for sex
workers. However where services are provided 85 countries say that nearly nine
out of 10 sex workers used a condom the last time they had sex.

Likewise for men who have sex with men—in capital cities the median coverage
was 55%. But levels of consistent condom use are insufficient. Although a
majority of surveyed men who have sex with men said that they used a condom
during their last sexual episode, only 13 countries reported more than 75%
consistent condom use, while 58 countries reported between 50%-75% condom
use. The number who know their HIV status is also low—fewer than one in
three tested for HIV in the past 12 months in South and South-East Asia and in
Western and Central Europe, regions where sex between men plays a key role in
national HIV epidemics.

According to country reports, nearly 80% of people who inject drugs reached
in surveys in 49 capital cities have access to safe injecting equipment. However
a separate 2010 study estimated that, globally, two needle-syringes (range
1–4) were distributed monthly per person who injects drugs—far too little to
effectively stop needle sharing and thus the transmission of HIV. Another study
estimates that people who inject drugs only use sterile equipment for 5% of
injections globally. Studies suggest there is a gender gap in services for drug
users whereby women who inject drugs have even poorer access to HIV services.

To end the AIDS epidemic, sex workers, men who have sex with men and people
who inject drugs cannot remain invisible. They have to be counted in. Getting
to zero will require better mapping and effective combination prevention.
That means combined behavioural, biomedical and structural strategies, both
intensively in specific populations in concentrated epidemics and across the
whole population in generalized epidemics.




                                                                                 Results   37
The treatment gap in low-
and middle-income countries
Antiretroviral therapy reached 8 million people by the end of 2011, a twenty-fold increase since
2003. In 2011, for the first time, a majority (54%) of people eligible for antiretroviral therapy in
low- and middle-income countries were receiving it. This chart shows the gap in 2011 between the
number of people receiving antiretroviral therapy and the number of people eligible for treatment.

Source: UNAIDS 2012 Global Report



                     People receiving HIV treatment 000 000
                    People eligible for HIV treatment 000 000



                        Middle East and North Africa
                                               17 000
                                              116 000




                  Eastern Europe and Central Asia
                                          130 000
                                          510 000




                                            Asia and Pacific
                                                    1 100 000
                                                   2 400 000




                                         Sub-Saharan Africa
                                                    6 200 000
                                                   11 000 000




                         Latin America and Caribbean
                                               580 000
                                               850 000




                                                   Globally
                                                    8 000 000
                                                   14 800 000




38   UNAIDS World AIDS Day Report 2012
treatment gap




85        %


75        %


54        %


44        %


32        %


46        %

                Results   39
UNAIDS World AIDS Day Report Results Summary
UNAIDS World AIDS Day Report Results Summary
UNAIDS World AIDS Day Report Results Summary
UNAIDS World AIDS Day Report Results Summary
UNAIDS World AIDS Day Report Results Summary
UNAIDS World AIDS Day Report Results Summary
UNAIDS World AIDS Day Report Results Summary

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UNAIDS World AIDS Day Report Results Summary

  • 1. UNAIDS World AIDS Day Report | 2012
  • 2.
  • 4. Foreword T he sun finds a way to shine into even the deepest parts of the forest. It is a metaphor for all of us who are working to restore hope and dignity around the world. In the history of the AIDS response there have been, and still exist, many obstacles to overcome but our path is clear—we work together to get results for all people. To the millions who have come together with compassion and determination, on this World AIDS Day we say, your blood, sweat and tears are changing the world. Results are accelerating There were more than 700 000 fewer new HIV infections globally in 2011 than in 2001. Africa has cut AIDS-related deaths by one third in the past six years. And as services have been scaled up, uptake has followed. In fact, what had taken a decade before is now being achieved in 24 months. In the past two years there has been a 60% increase in the number of people accessing lifesaving treatment—8 million people are on antiretroviral therapy. In most parts of the world we have seen a reduction in new HIV infections among young people. We have a special message to you. We can all see by the results that you already are “the change we want to see in the world”. We want to know more about your aspirations and dreams. We urge you to continue to engage and lead—and we are counting on you to use your youth as best as you possibly can. As we enter into the final years of working towards the Millennium Development Goals and the United Nations Political Declaration on HIV/AIDS, much remains to be done to reach our targets. 2 UNAIDS World AIDS Day Report 2012
  • 5. Treatment has not yet reached 7 million people. We have three years to eliminate all new HIV infections among children. The people who are most affected by HIV still experience marginalization and exclusion. The results we have seen show us that the momentum of our collective political will and follow through can overcome the biggest of obstacles and challenges—even the shortness of time. It shows us that with our steadfast determination and compassion—that invisible cord that binds us to other human beings regardless of race, gender, personal status, religion or national borders—we can get results for all people. Aung San Suu Kyi Michel Sidibé UNAIDS Global Advocate UNAIDS Executive Director for Zero Discrimination Results 3
  • 6. Keywords Countries like South Africa and India UNAIDS call for scale up services the elimination of new 81 countries increase 2012 HIV infections among domestic investments children in 2009 by 50% Reduction = in new HIV infections Reaching More pregnant investments + women + + + + Fewer deaths Young people Community Faster scale up of leadership engagement HIV treatment 4 UNAIDS World AIDS Day Report 2012
  • 7. Yay! Gap to fill by 2015 Key populations Results for HIV not reached people prevention = services – needed = – Marginalization Low HIV testing – uptake – HIV 50% of people living with HIV do not know treatment their HIV status needed 6.8 million people eligible and waiting for treatment Results 5
  • 8. At a glance A look at the number of people living with HIV in the world, 2011 Source: UNAIDS 2012 Global Report Number of AIDS-related deaths 1.7 million Global overview 34 million ± 50% know their HIV status New HIV infections 2.5 million People eligible for HIV treatment 14.8 million People on HIV treatment 8 million 6 UNAIDS World AIDS Day Report 2012
  • 9. Regional overview North America, Oceania Asia Eastern Europe Latin America Western and 53 000 4.8 million 1.4 million 1.4 million Central Europe 2.3 million caribbean Russian Federation 230 000 990 000 United States of America China 1.3 million 780 000 Middle Thailand Brazil East 480 000 470 000 and Indonesia North 370 000 Africa 300 000 Sub-Saharan Africa 23.5 million South Africa 5.1 million Uganda United Republic of Tanzania 1.2 million 1.3 million Nigeria 3 million Mozambique 1.2 million Zambia Zimbabwe 800 000 1 million Kenya 1.4 million Ethiopia 610 000 Results 7
  • 10. Tweetable Countries are making historic gains towards ending #AIDS: 700K fewer new HIV infections across the world in 2011 than in 2001 #Results
  • 11. Sustained progress in halting new HIV infections I n the last ten years the landscape of national HIV epidemics has changed dramatically, for the better in most countries, especially in sub-Saharan Africa. Countries are making historic gains towards ending the AIDS epidemic: 700 000 fewer new HIV infections across the world in 2011 than in 2001. Latest data show that a 50% reduction in the rate of new HIV infections (HIV incidence) has been achieved in 25 low- and middle-income countries between 2001 and 2011. More than half of these countries are in sub- Saharan Africa where the majority of the new HIV infections occur. In a further nine countries the rate of new HIV infections fell steeply—by at least one third between 2001 and 2011. The national declines in HIV incidence in populations shows that sustained investments and increased political leadership for the AIDS response are paying dividends. In particular, countries with a concurrent scale up of HIV prevention and treatment programmes are seeing a drop in new HIV infections to record lows. Prevention leads to behaviour change; treatment reduces a person’s viral load. Both reduce the potential for the virus to be transmitted. The historic slow-down indicates HIV prevention and treatment programmes are successfully reaching the people in need. In Southern Africa, where most countries have large numbers of people living with HIV or high HIV prevalence, the number of people acquiring HIV has been dramatically reduced. Between 2001 and 2011, in Malawi, the rate of new HIV infections dropped by 73%, in Botswana by 71%, in Namibia by 68%, in Zambia by 58% and in Zimbabwe by 50%. South Africa, the country with the largest number of HIV infections, reduced new HIV infections by 41%. In Swaziland, which has the highest HIV prevalence in the world, new HIV infections dropped by 37%. In West and Central Africa, Ghana was at the top of the list with a drop of 66% followed by Burkina Faso at 60% and Djibouti at 58%. The Central African Results 9
  • 12. Republic, Gabon, Rwanda and Togo, achieved significant declines of more than 50%. Other countries with significant declines in the region include Burundi, Cameroon, Mali and Sierra Leone where the decline was more than one third. Ethiopia achieved a 90% reduction in the rate of new HIV infections in the last decade. Despite a 25% reduction in sub-Saharan Africa, the region accounted for 72% of all new HIV infections worldwide in 2011. The region with the sharpest declines in number of new HIV infections is the Caribbean where there has been a drop of more than 42%. In Suriname, the rate of new HIV infections fell by 86% and in the Dominican Republic by 73%. A more than 50% decline was observed in the Bahamas, Barbados, Belize and Haiti. In Jamaica and Trinidad and Tobago, new HIV infections fell by more than one third. In Latin America, the number of new HIV infections has remained stable. In Asia and Oceania, Nepal drastically reduced new HIV infections by 91% and Cambodia by 88%. Four countries that account for a large number of people living with HIV in the region—India, Myanmar, Papua New Guinea and Thailand—reduced new HIV infections by more than 50%. Malaysia’s new infections dropped by 34%. However, the epidemic significantly increased in Bangladesh, Indonesia, Philippines and Sri Lanka. 10 UNAIDS World AIDS Day Report 2012
  • 13. Despite the encouraging news, national epidemics in many parts of the world continue to expand. There is an opportunity for the redoubling of energy and focus by these countries. In the Middle East and North Africa, the number of people newly infected with HIV increased by 35% between 2001 and 2011, and the rate of new HIV infections continues to rise in Eastern Europe and Central Asia. In Georgia, Kazakhstan, Kyrgyzstan and the Republic of Moldova the rate of new HIV infections rose by more than 25%. In the Russian Federation the annual number of new infections has dramatically increased in recent years, as reflected in an increase in reported cases of new HIV diagnoses, from less than 40 000 in 2006 to over 60 000 in 2011. The road from 2.5 million new HIV infections—the number in 2011—to zero new HIV infections is a long one, and there is a significant effort required to accelerate HIV prevention programmes. But the positive national trends for the most part compellingly indicate that with expanded and sustained HIV prevention and treatment programmes— that are evidence-informed and reach people at highest risk and need— rapid declines are possible. Results 11
  • 14. Incidence meter: Towards zero new HIV infections The rate of new HIV infections has been reduced by more than 50% among adults (15-49 years) in 25 countries between 2001 and 2011 Source: AIDSinfo .18 .02 0 52% .37 .10 29% Bahamas 45% 0 .02 .10 Mexico .03 0 .18 .0 .15 0 54% .22 0 73% .09 .03 .12 Mali 0 29% 66% 37% Haiti Dominican Republic Niger .13 .06 .29 54 0 .20 % .09 0 Barbados .08 Sierra Leone 33% 60% 56 0 .31 .08 40 Belize 0 .20 % 0 .15 0 Burkina Faso 66% Jamaica 0 .15 .36 Centra Trinidad and Tobago 0 .24 Rep 43% Ghana .23 86 % .02 0 .63 57 Cameroon 0 .11 % .34 0 Suriname 0 .55 Togo 0 54% .74 Gabon 0 .77 0 68% 2.39 Namibia 1.00 Percentage change in HIV incidence (2001-2011) 0 71 HIV incidence 2001 Bots HIV incidence 2011 86% .02 0 0 .11 So Country 12 UNAIDS World AIDS Day Report 2012
  • 15. .01 0 91% .09 Nepal .11 08 .03 .11 0 58% .27 .02 0 74% .10 Myanmar 57% Djibouti 0 .04 88% .01 6 % India 90 % .03 0 .07 .67 .03 0 .29 Cambodia al African .45 public .15 Ethiopia 53% .04 32 % 0 .05 .04 0 .66 Thailand 53% Kenya 34% .04 49 0 .05 0 Rwanda .31 0 % .09 Malaysia .08 Burundi 0 53% .09 58% .49 Papua New Guinea Zambia 1.05 1.89 0 72% 1.74 Malawi 50% 1.13 0 2.11 Zimbabwe 0 31% 1.63 Mozambique 1% 3.49 2.60 wana 1.43 0 37% 4.11 Swaziland 41% 2.42 outh Africa Results 13
  • 16. What keeps me going is the knowledge that ARVs are affordable and available…The number of people I know who have HIV and are living a normal life, even starting families, really keeps me going. Person living with HIV, Uganda
  • 17. Record access to HIV treatment, record drop in AIDS-related deaths T he latest data gathered from countries around the world tell a story of clear success. Sustained investments in access to antiretroviral therapy by donors and national governments have led to record numbers of lives being saved in the past six years. In 2011 more than half a million fewer people died from AIDS-related illnesses than six years earlier. It’s a dramatic turning point. In 14 countries, AIDS-related deaths dropped by more than 50% between 2005 and 2011. Numbers can quantify, but alone cannot express the impact of each averted death on the whole community, including its children. For the first time, a majority of people eligible for HIV treatment in low- and middle-income countries—54%, a record eight million people—were receiving antiretroviral therapy. This means more people than ever who are living with HIV are being helped to live longer, healthier and more productive lives. Lessons learned through the past decade have led to improved collaboration between governments, donors, partners, and a combination of innovation, efficiency and increased domestic investments have seen a return on investment unparalleled in the AIDS response. The part of the world most impacted by HIV, sub-Saharan Africa, has cut the number of people dying of AIDS-related causes by 32% between 2005 and 2011. The largest drop in AIDS-related deaths was in some of those countries where HIV has the strongest grip. In South Africa, 100 000 fewer deaths occurred, followed by nearly 90 000 in Zimbabwe, 71 000 in Kenya, 59 000 in Ethiopia and 48 000 in the United Republic of Tanzania. A number of the region’s countries with smaller populations but high HIV prevalence have also made significant gains in averting deaths related to AIDS. Botswana cut AIDS-related deaths by 71%, Rwanda by 68%, Namibia by 60%, Zambia by 56% and Burundi and Côte d’Ivoire by 51%. Benin, Burkina Faso, Eritrea, Guniea, Lesotho, Malawi and Mali all reduced AIDS- related deaths by one third. The countries of the Caribbean experienced a 48% decline in AIDS-related deaths while in Oceania the drop was 41%. The Dominican Republic had Results 15
  • 18. Declines in TB-related AIDS deaths among people living with HIV, 2005-2011 Source: Global Tuberculosis Report 2012. Geneva, World Health Organization, 2012: www.who.int/tb/publications/global_report/en Global estimate Africa estimate 600 000 Number of TB-related AIDS deaths 9% among people living with HIV 500 000 13% 10% 400 000 15% 300 000 Four years 24 months 200 000 100 000 0 2005 2006 2007 2008 2009 2010 2011 61% fewer people dying from AIDS-related causes while Guyana, Haiti, Jamaica and Suriname saw a more than 40% reduction. In Asia, Cambodia reduced its AIDS-related deaths by 77% and Thailand by 49%. Peru reduced AIDS-related deaths by 55% and Mexico by 27%. Countries like Argentina, Brazil, Chile, Ecuador, El Salvador, Nicaragua, Paraguay and Venezuela provided access to drugs to between 60% and 79% of people eligible for HIV treatment. Worrisome increases in AIDS-related mortality were observed in Eastern Europe and Central Asia (21%) and the Middle East and North Africa (17%). However, Djibouti showed a decline of 26% in AIDS-related deaths. Impressive gains were also made in cutting deaths from tuberculosis (TB) in people living with HIV. Between 2004 and 2011, TB-related AIDS deaths fell by 25% worldwide and by 28% in sub-Saharan Africa. In the last 24 months, a 13% decrease in TB-related AIDS deaths was observed in 2011, compared to a 10% decrease over the four-year period between 2004 and 2008. This accomplishment is due to record numbers of people with HIV/TB co- infection accessing antiretroviral treatment—a 45% increase between 2009 and 2011. India, Kenya, South Africa, Zambia and Zimbabwe accounted for two thirds of all new people with HIV/TB co-infection being treated, but much more needs to be done. No-one should die of TB and HIV. How have lives been saved? In just the past two years, HIV treatment access grew by 63% around the world. The massive scale up over the last 24 months enabled tens of thousands of people living with HIV to receive lifesaving antiretroviral therapy for the first time. The increase came at a time when international funding for AIDS remained flat. Countries are better implementing programmes. They have used a combination of innovation, efficiency and increased domestic investments to sustain the rapid growth in access to treatment. The price of 16 UNAIDS World AIDS Day Report 2012
  • 19. antiretroviral drugs has reduced dramatically from US$ 10 000 per person a decade ago to around US$ 100 annually in some countries. In sub-Saharan Africa, a record 2.3 million people were added to treatment programmes in the last two years—an increase of 59%. South Africa scaled up its treatment services to reach 1.7 million people—an increase of 75% in the last two years. In Zimbabwe, 260 000 additional people accessed HIV treatment, registering a 118% expansion rate. In Kenya, 200 000 people were added—a 59% increase. Upwards of 100 000 people living with HIV were enrolled in HIV treatment in Malawi, Mozambique, Nigeria, Uganda and Zambia each. Five countries in the region have achieved more than 80% coverage of HIV treatment—Botswana, Namibia, Rwanda, Swaziland and Zambia. Outside of sub-Saharan Africa, China has increased the number of people on HIV treatment by nearly 50% in the last year alone. Since 1995, antiretroviral therapy has saved 14 million life years in low- and middle-income countries, including nine million in sub-Saharan Africa. Fewer deaths from AIDS-related illnesses has transformed societies: more people, regaining their health, are returning to work and taking care of their families. However, the gap between people who can access treatment and people in need is still very large, nearly 46%, and as the demand for treatment as prevention continues to rise and increasingly outstrips availability, this treatment gap is set to grow. Results 17
  • 20. Showing impact: HIV treatment saves lives The number of people dying from AIDS-related causes began to decline in the mid-2000s because of scaled up antiretroviral therapy and the steady decline in HIV incidence since the peak of the epidemic in 1997. In 2011, this decline continued, with evidence showing that the drop in the number of people dying from AIDS-related causes is accelerating in several countries. 673 413 Source: UNAIDS 2012 Global Report 39 Germany % 18 28 Cro 508 373 27 Bahamas % 1 9,925 6,553 6,678 27 4,862 % % 61 10,884 5,825 4,323 1,696 % 34% 49% 46 3,208 1,646 Mali 6,157 4,028 14,982 1 Mexico Haiti Dominican Republic 31% 12,717 6,758 Jamaica 36 26 35% 47% 28% Guinea Central Af Burkina Faso Republ Barbados 5,451 2,759 49 % 3,353 2,331 30% 51% 46,684 22,800 600 243 Benin 60 % 675 294 Liberia Côte d’Ivoire 6,614 4,630 Guyana 56% 21,803 15,337 30 % Suriname 30 Ghana % Congo 70,685 56 6,722 3,029 55% 2,196 1,592 Zam Peru 28Bolivia % 399 299 12,825 5,184 25 Paraguay % 60 % Namibia AIDS-related deaths in 2005 370,874 AIDS-related deaths in 2011 46,684 22,800 South 27 Percentage of decline in AIDS-related deaths 51% Country (2005 - 2011) 18 UNAIDS World AIDS Day Report 2012
  • 21. 13 8% oatia 15,967 12,034 25% 2,121 1,402 Chad 10,278 34% Eritrea 45,146 23,147 % 1,184 880 49 % 26 113,825 53,831 % 53% Thailand frican lic Djibouti 6,232 1,449 77 Ethiopia % Cambodia 19,788 6,353 133,503 61,691 68 % 54 % 2,113 1,134 Rwanda Kenya 131,704 83,528 46% 11,904 51 5,787 % 37% United Republic Papua New Guinea 31,282 of Tanzania Burundi 6% mbia 14,542 4,208 76,589 43,858 71 Botswana % 43Malawi % 147,876 58,339 270,190 61% Zimbabwe 7 % h Africa 9,914 6,813 21,714 13,986 31 % 36% Lesotho Swaziland Results 19
  • 22. Tweetable The aspiration that the world can fully fund the AIDS response is achievable w/ continued shared responsibility & global solidarity #Results
  • 23. Global solidarity and shared responsibility is sustaining investments in AIDS L ow- and middle-income countries are driving the global increase in HIV investments. The global gap in resources needed by 2015 has now dropped to about 30%. The aspiration that the world can fully fund the AIDS response is achievable with continued shared responsibility and global solidarity. For the first time ever, domestic investments have surpassed global giving for AIDS, tipping the aid dependency balance. Domestic investments rose from US$ 3.9 billion in 2005 to almost US$ 8.6 billion in 2011. Some 81 countries increased domestic investments for the AIDS response by more than 50% between 2006 and 2011. However, international investments still remain critical and indispensable. Increased country ownership for domestic investments South Africa is the country that has made the highest domestic investment in AIDS among all low- and middle-income countries. It alone invested US$ 1.9 billion last year from public sources, resulting in a five-fold increase between 2006 and 2011. This strategic leadership is an example being echoed across the region. Kenya doubled its domestic investments for AIDS between 2008 and 2010, and Togo did the same between 2007 and 2010. This year, Zambia has put a massive injection of funds into its health budget, increasing it by 45%. Many middle-income countries are increasingly taking responsibility for funding the majority of their AIDS response needs. Exceptional leadership is coming from the world’s fastest-growing emerging economies: Brazil, Russia, India, China and South Africa (BRICS). Together, they contribute to more than half of all domestic spending on AIDS in low- and middle-income countries. Their momentum is unparalleled, having increased domestic public spending by more than 122% between 2006 and 2011. Brazil and Russia fund almost all of their national AIDS responses from domestic sources. Brazil has for years invested adequately and focussed on Results 21
  • 24. the most vulnerable and marginalized and reaped benefits. Russia on the other hand has not realised the same value for money as its AIDS investment strategy is not optimized to its epidemic patterns. China currently invests more than 80% domestically, and the country has announced it will fully fund its AIDS response in the coming years. India, too, has committed to increase domestic funding to more than 90% in its next phase of the AIDS response. These fast- growing economies have the potential to support others in the region, as well as exert leadership and influence on the AIDS response, both locally and globally. International investments—fragile status quo Against the backdrop of continued economic uncertainties in high-income countries, international investments have remained stable at around US$ 8.2 billion in 2011, although the economic downturn has impacted development assistance budgets. The healthy growth in domestic investments is most welcome, and it has indeed become critical to service delivery. However, international assistance remains a crucial lifeline for many countries with low income and high HIV prevalence that have little fiscal space to absorb cuts in development aid. In 26 of 33 countries in sub-Saharan Africa, donor support accounts for more than half of the current AIDS response investments in the region. The lion’s share of international assistance is directed towards supporting HIV treatment, in particular in high burden countries in sub-Saharan Africa. This could render gains in coverage of lifesaving treatments fragile should international assistance drop in the coming years. It is heartening to note many high-income countries have maintained their current levels of funding, in spite of the persistent fragility of their economies. The United States of America continues to be the largest international donor—both bilaterally and through multilateral funding channels—accounting for 48% of all such assistance. As economies recover, international investments must increase, and the donor base has to become more diversified and include the increasing capabilities of emerging economy countries. 22 UNAIDS World AIDS Day Report 2012
  • 25. Making strategic use of AIDS investments An important strategy for enhancing value for money is to maximize impact and cost-efficiency by focusing limited resources where the epidemic is most severe and on the populations in the greatest need—the spending pattern differs between regions and countries according to their type of epidemic. In some settings, investing more strategically requires focusing a larger share of prevention spending on the general population. In other countries, the focus needs to be on the key populations that represent the largest percentage of people newly infected. It is estimated that by 2015 the share of investment needs for basic prevention programmes, such as male circumcision, preventing mother-to-child transmission and key populations at higher risk, will have to be increased. For example, today, programmes to reach key populations receive only 4% of investments globally, but for an optimized HIV response in 2015, this share will need to be about 14%. Closing the resource gap Multiple avenues will need to be pursued if the world is to reach the target of mobilizing US$ 22-24 billion annually for the response. Countries should ensure that HIV spending is focused on effective investments and take steps to further increase their domestic spending for the AIDS response, including developing innovative and sustainable AIDS funding sources. Efforts must be intensified to improve the efficiency of AIDS spending through such means as capturing productivity gains, continuing to reduce the price of antiretroviral medicines, integrating services and improving service delivery. Economic growth in low- and middle-income countries can help expand the fiscal space for HIV investment, and further efforts are needed to cultivate emerging economies as international AIDS donors. In the context of shared responsibility and global solidarity, current international donors must also remain engaged in closing the resource gap for countries in need. Only by applying the investment approach and working within a framework of shared responsibility will countries reach their 2015 goal. Results 23
  • 26. A smaller funding gap to close There is increasing country ownership and shared responsibility for investments in the AIDS response. Domestic investments now account for the majority of AIDS investments. The gap for investment needs in 2015 is closing, but much more can be done to make investments effective and efficient. Resources available for HIV in low- and middle- income countries, 2007-2011 Source: UNAIDS 2012 Global Report 2011 2010 2009 2008 2007 43% 42% 44% 50% 51% 58% 50% 56% 57% 49% Domestic International International investment Domestic investment 24 UNAIDS World AIDS Day Report 2012
  • 27. Resources needed for HIV in low- and middle-income countries in 2015 Source: UNAIDS 2012 Global Report Need in 2015 US$ 24 billion Current HIV investments US$ 16.8 billion Key populations at higher risk US$ 1.7 billion Male circumcision US$ 228 million US$ 134.5 million US$ 26.5 million Investments for basic HIV prevention and treatment Condom promotion programmes US$ 300 million US$ 10.7 billion US$ 110 million US$ 5.7 billion Behavioural Change US$ 625 million US$ 70 million Treatment, care and support US$ 6.8 billion Prevention of mother- US$ 5.1 billion to-child transmission US$ 1.1 billion Investment needs in 2015 US$ 201 million Current investments Results 25
  • 28. Having been born with HIV, I have always lived with the virus. Today it represents taking a couple of pills two times each day… and it doesn’t have to be anything more than that. Alejandro, Argentina
  • 29. Declining new HIV infections in children and young people Rapid declines in new HIV infections among children N ew HIV infections in children dropped by 43% from 2003 to 2011. In fact, new HIV infections in children declined by 24% in the last two years alone, which is much sharper than the 19% drop seen in the four year period between 2004 and 2008. Half of all new HIV infections averted—in adults and children—in the 24-month period between 2009 and 2011 were among newborn children. This reduction has been accelerated by the rapid progress made in the last two years in giving more women living with HIV access to prevention and treatment services. When women living with HIV receive antiretroviral prophylaxis during pregnancy, delivery and breastfeeding, the risk of HIV transmission is reduced to less than 5%.This accelerated progress in cutting new HIV infections has happened as countries move forward in implementing the Global Plan towards the elimination of new HIV infections among children by 2015 and keeping their mothers alive. However, acute geographic inequalities continue. Of the children who acquired HIV in 2011, close to zero live in high-income countries and more than 90% live in sub-Saharan Africa. Encouragingly, the number of children newly infected in the region fell by 24% from 2009 to 2011. Countries with generalized epidemics have the overwhelming majority of children newly infected and they have made major gains during the past decade. In six countries—Burundi, Kenya, Namibia, South Africa, Togo and Zambia—the number of children newly infected fell by between 40% and 59% from 2009 to 2011. In 16 additional countries, declines of between 20% and 39% occurred during the same period. The number of children acquiring HIV infection has declined significantly in the Caribbean (32%) and Oceania (36%), with a more modest decline in Asia (12%). New infections also dropped in Latin America (24%) and Eastern Europe and Central Asia (13%), regions that had already significantly reduced the numbers of children newly acquiring HIV infection. The Middle East and Results 27
  • 30. New HIV infections among children (0-14 years old) 2003-2011 Source: UNAIDS 2012 Global Report 600 000 Number of children newly infected 23% 500 000 400 000 24% with HIV 300 000 Six years 24 months 200 000 100 000 0 2003 2004 2005 2006 2007 2008 2009 2010 2011 North Africa is the only region that has yet to see a reduction in the number of children newly infected. Reaching pregnant women living with HIV Although reductions in the number of adults acquiring HIV infection are helping to lower children’s risk of HIV, recent gains in bringing antiretroviral and infant feeding–based prevention services to scale are primarily responsible for the sharp reductions in the number of children newly infected. From 2009 to 2011, antiretroviral prophylaxis prevented 409 000 children from acquiring HIV infection in low- and middle-income countries. In low- and middle-income countries, coverage of effective antiretroviral regimens for preventing mother-to-child transmission reached 57% in 2011. Apart from high-income countries, which have long had near-universal coverage for antiretroviral medicines for pregnant women, the Caribbean is the only region approaching similarly high coverage levels at 79%. In sub-Saharan Africa, the region where 92% of the world’s HIV-positive pregnant women live, 59% of them received antiretroviral therapy or prophylaxis during pregnancy and delivery in 2011. Ensuring a mother living with HIV has access to HIV treatment not only has health benefits for her, but also for her family. Studies indicate that children whose mothers stay alive and healthy have a decreased risk of death regardless of the child’s HIV status. Recent estimates suggest that pregnancy- related deaths among women living with HIV have declined from 46 000 in 2005 to an estimated 37 000 in 2010. More effort is needed to ensure that pregnant women tested for HIV during antenatal care are also tested for eligibility for antiretroviral therapy. 28 UNAIDS World AIDS Day Report 2012
  • 31. Young people—bringing change, shaping the future The actions of young people are shaping the future of AIDS across the world. Between 2001 and 2011, prevalence of HIV—a proxy indicator of new HIV infections—fell by nearly 27% among young people aged 15-24 globally. The largest progress was seen in South and South-East Asia where HIV prevalence among young men and women fell by 50%. Sub-Saharan Africa and the Caribbean followed with a drop of more than 35% among young men and women. In Latin America, HIV prevalence decreased by nearly 20% among young people. Significantly, the decline was much higher at 33% among young men, the group where the majority of new HIV infections among young people in Latin America occur. This encouraging trend is reversed in Eastern Europe and Central Asia where there has been a 20% increase in new HIV infections among young people. The majority of young people who are acquiring HIV are those who inject drugs, very few of whom have access to evidence-informed HIV prevention and treatment services. Today, young people account for 40% of all new adult HIV infections. Each day, more than 2400 young people become infected with HIV—and some five million young people are living with HIV. Young people are a fulcrum. They remain at the centre of the epidemic and they have the power, through their leadership, to definitively change the course of the AIDS epidemic. Today, they are already doing so. Results 29
  • 32. Global plan progress Much progress has been made in stopping new HIV infections among children in the 21 countries covered by the Global Plan towards the elimination of new HIV infections among children by 2015 and keeping their mothers alive. This chart provides a snapshot of progress made against three select indicators—1) the number of children acquiring HIV infections from mother-to-child HIV transmission; 2) the percentage of women receiving antiretroviral drugs (excluding single dose nevirapine) to reduce transmission during pregnancy and 3) the percentage of pregnant women living with HIV eligible for HIV treatment receiving antiretroviral therapy. Source: A progress report on the Global Plan, 2012. UNAIDS 5300 500 1900 0 0 16 % 5300 100 0 0 93 % 700 100 0 0 38 % 2700 100 0% 77% 0% Angola Botswana Burundi 13000 2700 13200 0 0 24 % 18900 100 0 0 75 % 3900 100 0 0 67% 23200 100 24% 0% 61% Ethiopia Ghana Kenya 69300 800 29100 0 0 85 % 1900 100 0 0 18 % 70900 100 0 0 > 95% 56500 100 27% 84% 69% Namibia Nigeria South Africa Number of new HIV infections among children, 2011 500 2015 target Percentage of women receiving 93 % 0 700 Number of new HIV infections among children, 2009 antiretroviral therapy to reduce HIV transmission during pregnancy 0 100 77% Percentage of pregnant women living with HIV receiving antiretroviral therapy Country 30 UNAIDS World AIDS Day Report 2012
  • 33. 6800 4800 4400 0 0 54 % 8900 100 0 0 19% 13 % 5000 100 0 0 68 % 5400 100 28% 0% Cameroon Chad Côte d’Ivoire 3700 15700 27100 0 0 63 % 4700 100 0 0 53 % 21300 100 0 0 51% 28400 100 25% 45% 51% Lesotho Malawi Mozambique 1200 20600 21900 0 0 95 % 2000 100 0 0 15% 50 % 27300 100 0 0 74 % 26900 100 40% 71% Swaziland Uganda United Republic of Tanzania 9700 9500 0 0 85 % 21000 100 0 0 78 % 17700 100 51% 88% Zambia Zimbabwe Results 31
  • 34. I have learned to rise above stigma by standing up for what I believe in. I speak of universal access to comprehensive health care for all—without any form of stigma and discrimination. Michael, Nigeria
  • 35. The miles we need to go in 1000 days A mere thousand days remain before the world has to achieve its 2015 global AIDS targets—reduce sexual transmission of HIV and new HIV infections among people who inject drugs by 50%, eliminate new HIV infections among children, provide antiretroviral treatment to 15 million people and reduce TB-related AIDS deaths by 50%. To enable this to happen, nations committed to investing up to US$ 24 billion annually by 2015. The destination is clear. Strides forward have to be long, steady and purposeful. Multiplying the power of HIV treatment Antiretroviral therapy has emerged as a powerful force for saving lives. Yet despite the unprecedented growth in numbers of people on HIV treatment in the last two years, nearly half of all who are eligible (having a CD4 count of less than 350 per ml, the current threshold) do not have access—that’s 6.8 million people in 2011. Half will die within 24 months if they don’t start antiretroviral therapy. The number eligible will rise as more of the 34 million people living with HIV become eligible for treatment for their own health. UNAIDS estimates that an additional four million discordant couples (where one partner is living with HIV) would benefit from access to antiretroviral therapy to protect their partners from HIV. Using antiretroviral therapy as a prophylaxis for people at high risk of HIV infection is also gaining momentum. HIV treatment is for life and people living with HIV need to take pills every day without fail. There is an urgent need to improve retention rates for people enrolled in HIV treatment as studies show that adherence can fall as people regain good health. Nearly half of the people who began antiretroviral therapy at a treatment centre in Malawi are no longer in care five years later and this proportion is nearly 40% in centres in Kenya. Where communities actively engage in providing care, retention rates are steady. Two-year retention rates in Mozambique climbed to 98% in a programme Results 33
  • 36. where community support strategies were introduced to complement clinical services. Though treatment prices continue to plummet, second and third line treatment regimens are still very expensive and many countries experience human resource constraints for delivery. Both programme management costs and drug prices can and will have to fall significantly to contain the treatment bottom line. A number of strategies would help. Programmes can better leverage opportunities to link treatment to other services like couples counselling and testing or opioid substitution therapy. A shift from international to domestic production of drugs and a strong vigilance on trade agreements could spread the risks to sustained delivery of lifesaving medicines in the medium and long-term. Despite considerable increases in domestic funding, countries continue to rely on overseas development assistance for their HIV response. International funding accounted for more than half of spending in 59 countries and contributed more than 75% of spending in 43 of the 102 low- and middle-income countries. Knowing your HIV status Increases in access to treatment can be partly attributed to a growing number of people living with HIV knowing their HIV status. In Ethiopia an estimated 21% of adult men were tested for HIV in 2011 up from approximately 2% in 2005. In Rwanda nearly 39% of adult women were tested for HIV in 2010 compared to about 12% in 2005. In Lesotho an estimated 42% of adult women reported that they had been tested for HIV in 2009 compared to about 6% in 2004. Surveys in 14 countries in sub-Saharan Africa between 2004 and 2011 found significantly more adults had taken an HIV test in the previous year. Multi-disease prevention campaigns in Kenya and Uganda show the potential of innovative community- based HIV testing and counselling approaches. In Kenya around 23% of adult men were tested for HIV between 2008 and 2009 compared to 8% in 2003. Although the trend towards increased population-based testing rates is encouraging, the available evidence does not conclusively show that HIV testing programmes are reaching the people at highest risk. At the end of 2011 it is estimated that only half of all people living with HIV know their HIV status. Reaching children and pregnant women living with HIV While much progress has been made in sub-Saharan Africa in increasing services to prevent mother-to-child transmission of HIV, reported coverage is substantially lower in South and South-East Asia (18%) and in the Middle East and North Africa (7%). It is also difficult to estimate service needs and coverage among women at highest risk of HIV in countries with concentrated epidemics. 34 UNAIDS World AIDS Day Report 2012
  • 37. The percentage of treatment-eligible pregnant women living with HIV who are receiving antiretroviral therapy was 30% in 2011—lower than the estimated 54% coverage for all adults eligible according to WHO guidelines. Qualitative research is needed to determine why despite improving access to health care, pregnant women are not starting, or being reported to start, antiretroviral therapy. While the drop in new adult HIV infections is helping to lower children’s risk of acquiring HIV, the recent growth of antiretroviral- and infant feeding-based prevention services are primarily responsible for the sharp reductions in the number of children newly infected. From 2009 to 2011, antiretroviral prophylaxis prevented 409 000 children from acquiring HIV infection in low- and middle- income countries. Greater efforts are required to stop primary HIV infection among women and provide reproductive and sexual health services for women living with HIV who do not want to get pregnant. At the same time there are disturbing reports of forced sterilization of women living with HIV in many parts of the world—acts which are a violation of human rights and a gross abuse of authority and trust. Bringing combination HIV prevention programmes to scale There were 2.7 million new HIV infections among adults and children in 2011—a long way from the vision of getting to zero. Despite impressive gains, sub-Saharan Africa accounted for 72% of all new HIV infections and new HIV infections are rising in Eastern Europe and Central Asia. HIV prevention gains can be accelerated if all the current HIV prevention options are made available to people at risk in a smart and efficient manner. Male circumcision: Scaling up voluntary medical male circumcision has the potential to prevent an estimated one in five new HIV infections in Eastern and Southern Africa by 2025. The unit cost is relatively low and is a one-time rather than lifelong expenditure. Nevertheless, countries allocate relatively few resources towards this service—less than 2% of total HIV expenditure in six of the 14 priority countries where data is available. In Kenya nearly 54% of adults in the Nyanza province have been circumcised and more than 20% in Ethiopia and Swaziland. But in six countries—Malawi, Mozambique, Namibia, Rwanda, Uganda and Zimbabwe—less than 5% of the target number of men had been voluntarily circumcised by end of 2011. Changing sexual behaviour to avert HIV: Sexual behaviour among men and women has changed to become safer in numerous countries with generalized epidemics including Kenya, Malawi, Mozambique, Namibia, Nigeria and Zambia. In other countries—such as Côte d’Ivoire, Guyana and Rwanda—sexual risk behaviour is increasing, highlighting the need to intensify support for behaviour change efforts. Results 35
  • 38. Age-appropriate sexuality education may increase knowledge and contribute to more responsible sexual behaviour however there are gaps in even basic knowledge about HIV and its transmission. In 26 of 31 countries with generalized epidemics in which nationally representative surveys were recently carried out, less than 50% of young women have comprehensive and correct knowledge about HIV. Although population-level behaviour change has been shown to reduce the prevalence of HIV infection in several countries with generalized epidemics, linking behaviour change programming to specific HIV outcomes remains challenging. Increasing consistent, correct, condom use: Condom use is a critical element of combination HIV prevention and one of the most efficient technologies available to reduce the sexual transmission of HIV. Although levels of reported condom use appear to be increasing in several countries with a high HIV prevalence, recent data from nationally representative surveys indicate declines in Benin, Burkina Faso, Côte d’Ivoire and Uganda. The United Nations Population Fund (UNFPA) estimates that only nine donor- provided male condoms were available for every man aged 15–49 years in sub-Saharan Africa in 2011 and one female condom for every 10 women aged 15–49 years in the region. Less is known about the condoms directly procured by low- and middle-income countries. One estimate suggests more than two billion condoms were directly procured in 2010, far short of the 13 billion estimated for HIV prevention in 2015. Reaching populations at highest risk: HIV continues to have a disproportionate impact on sex workers, men who have sex with men and people who inject drugs. A recent review of data in 50 countries showed that 12% of female sex workers are living with HIV and the chance of women who engage in sex work being infected is 13.5 times higher than others. Often countries with generalized epidemics—where more than one in 100 adults have HIV—fail to recognize the severity of burden faced by sex workers, nearly one in four of whom in their capital cities are living with HIV. Similar trends are seen among men who have sex with men. Go to any capital city in the world, men who have sex with men are significantly more likely to have HIV—on average 13 times more than the general population. As global HIV prevalence trends appear to have stabilized there is disturbing evidence suggesting that global HIV prevalence among men who have sex with men may have increased between 2010 and 2012. People who inject drugs are the worst off: evidence from 49 countries shows that their risk of being infected with HIV is 22 times higher than the general population. In 11 countries the chances are 50 fold higher. 36 UNAIDS World AIDS Day Report 2012
  • 39. In countries of Eastern Europe up to 40% of new HIV infections occur among people who inject drugs and their sexual partners. In Armenia, in addition to drug use, nearly a quarter of new infections occur among men who have sex with men. Popular opinion in countries with generalized epidemics is that HIV infection is found evenly across the adult population. Evidence points otherwise. For example, modelling studies conducted in Kenya show that 33 out of every 100 new HIV infections occur among sex workers, their clients, people who inject drugs, men who have sex with men and people in prisons. About two thirds of countries report having risk reduction programmes for sex workers. New data from surveys conducted in capital cities of 58 countries suggest that median coverage of HIV prevention services is 56%, up very slightly from 2010. Coverage is lower in countries lacking legal protection for sex workers. However where services are provided 85 countries say that nearly nine out of 10 sex workers used a condom the last time they had sex. Likewise for men who have sex with men—in capital cities the median coverage was 55%. But levels of consistent condom use are insufficient. Although a majority of surveyed men who have sex with men said that they used a condom during their last sexual episode, only 13 countries reported more than 75% consistent condom use, while 58 countries reported between 50%-75% condom use. The number who know their HIV status is also low—fewer than one in three tested for HIV in the past 12 months in South and South-East Asia and in Western and Central Europe, regions where sex between men plays a key role in national HIV epidemics. According to country reports, nearly 80% of people who inject drugs reached in surveys in 49 capital cities have access to safe injecting equipment. However a separate 2010 study estimated that, globally, two needle-syringes (range 1–4) were distributed monthly per person who injects drugs—far too little to effectively stop needle sharing and thus the transmission of HIV. Another study estimates that people who inject drugs only use sterile equipment for 5% of injections globally. Studies suggest there is a gender gap in services for drug users whereby women who inject drugs have even poorer access to HIV services. To end the AIDS epidemic, sex workers, men who have sex with men and people who inject drugs cannot remain invisible. They have to be counted in. Getting to zero will require better mapping and effective combination prevention. That means combined behavioural, biomedical and structural strategies, both intensively in specific populations in concentrated epidemics and across the whole population in generalized epidemics. Results 37
  • 40. The treatment gap in low- and middle-income countries Antiretroviral therapy reached 8 million people by the end of 2011, a twenty-fold increase since 2003. In 2011, for the first time, a majority (54%) of people eligible for antiretroviral therapy in low- and middle-income countries were receiving it. This chart shows the gap in 2011 between the number of people receiving antiretroviral therapy and the number of people eligible for treatment. Source: UNAIDS 2012 Global Report People receiving HIV treatment 000 000 People eligible for HIV treatment 000 000 Middle East and North Africa 17 000 116 000 Eastern Europe and Central Asia 130 000 510 000 Asia and Pacific 1 100 000 2 400 000 Sub-Saharan Africa 6 200 000 11 000 000 Latin America and Caribbean 580 000 850 000 Globally 8 000 000 14 800 000 38 UNAIDS World AIDS Day Report 2012
  • 41. treatment gap 85 % 75 % 54 % 44 % 32 % 46 % Results 39