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Carcinoma Rectum

 A CASE PRESENTATION



  DR. JOY ZAKHARIA RAB
     ASSISTANT REGISTRAR
       SURGERY UNIT – I
       SBMCH,BARISAL.
Mr. Aiub Ali
     65 yrs
Before operation
Case presentation

1. PARTICULARS OF THE PATIENT:


Name:             Ayub Ali         Date Admission:    29/08/09
Father’s name:    Late Abdul Ali   Hospital :         SBMCH
Age:              65 years.        Department :       SU-I
Sex:              male.            Ward :              11
Marital status:   married .        Bed :               16
Religion:         Islam.
Occupation:       farmer
Social status :   Poor
Address:          Kawer Char
                  Barisal Sadar
                  Dist- Barisal
Case presentation


2. PRESENTING COMPLAINTS :

   Weakness for 6 months
   Feeling of incomplete defecation for 3 months
   Pain or discomfort during defecation for same duration
   Per rectal bleeding for 3 months
Case presentation

3. HISTORY OF PRESENT ILLNESS:

 According to the statement of the patient he was quite
 well 6 months back. Since then he developed nausea
 and found himself unwilling to do any daily activities
 due to unusual weakness. He went to village doctor
 who advised him some vitamin tablets but these were
 not very fruitful to overcome his weakness or nausea.
 Then after 3 months he noticed passing of hard stool
 followed by small amount of bleeding at end of
 defecation.
Case presentation
3. HISTORY OF PRESENT ILLNESS:
 He ignored this bleeding and thought this may
 be due to constipation. But after few days he
 felt abdominal cramp which made him to get up
 early in the morning due to urge for defecation
 but only some amount of muciod watery stool
 came out which could not satisfy his defecation
 urge, as well as passage of rectal bleeding didn’t
 stop. And for last 15 days rectal bleeding
 worsened so he came to our hospital for better
 management.
Case presentation

4. HISTORY OF PAST ILLNESS:
  HTN.

5. PERSONAL HISTORY:
  Diet habit :
        He took high fibre and roughage
        Vegetables almost daily
        Less animal fat
        Red meat usually once in a month

  Nonsmoker
  Nonalcoholic .

6. FAMILY HISTORY:
  None of His family members were suffering from this type of disease
Case presentation


7. DRUG HISTORY:
             Anti-hypertensive:
                    Tenoren
                    Amdocal
             Syp. Antacid



8. HISTORY OF IMMUNIZATION: Not Completed.
Case presentation
9. GENERAL EXAMINATION:

 Appearance:       ill looking            Anemia     : present
 Height      :     5 ft. 2 inches         Jaundice   : absent.
 Weight      :     50 kg.                 Edema      : absent.
 Body build :      Below average.         Pulse      : 80/min.
 Decubitus :       on patient’s choice.   B.P        :160/100mm/Hg.
 Dehydration:      absent
                                          Temp.      : 98`F
 Enlarged lymph node: absent.
 Nutrition :       below average.         RR         : 22 breaths/min.
Case presentation


10. SYSTEMIC EXAMINATION:

                         THE ABDOMEN
A. INSPECTION:
         Shape                 : Scaphoid
         Flanks                : not full.
         Umbilicus             : normal, centrally placed.
         Visible vein          : absent.
         Visible pulsation     : absent.
         Visible peristalsis   : absent.
         Visible swelling      : absent.
         Hernial orifices      : intact.
         Scar                  : absent.
Case presentation
The Abdomen cont ...

B. PALPATION:
                       1. SUPERFICAL PALPATION:

      Local temperature     : not raised.
      Tenderness            : absent.
      Muscle guard/Rigidity : absent


                          2. DEEP PALPATION:

      Liver                     : not enlarged.
      Gallbladder               : non palpable.
      Spleen                    : non palpable .
      Kidneys                   : kidneys were nonballotable.
Case presentation
The Abdomen cont ...



C. PERCUSSION :
              Percussion note : Normal.

D. AUSCULTATION :
              Bowel sound      : normal.

E. DRE FINDINGS : an annular growth encircling the whole
   circumference of the rectum which was hard in consistency with
   irregular margin associated with multiple small polypoid lesion
   around the growth which seems to be fixed with the surrounding
   muscles and involving the anal sphincter was found about 3 cm
   from the anal verge.
Case presentation

11. OTHER SYSTEMS EXAMINATION :



    Cardiovascular system     : normal.

    Respiratory system        : normal.

    Nervous system            : normal.

    Genito Urinary System     : normal.
Case presentation




12. CLINICAL DIAGNOSIS:

             Carcinoma of rectum
Case presentation
13. INVESTIGATIONS :
    A. COMPLETE BLOOD COUNT:
         Total Count :     8000/ cmm of blood
         Differential Count :
                               Neutrophil – 57%
                               Lymphocyte count – 37%
                               Mono cyte- 01%
                               Eosinophil – 05%
                               Basophil – 00%
         Hb%                  : 50%.
         ESR                  : 40 mm in 1st hour.
        (anaemia was corrected by 2 unit blood transfusion)
      B. BLOOD FOR RBS AND SERUM CREATININE:
        RBS – 310 mg/dl
             112 mg/dl after control with inj. insulin
       Creatinine – 0.9mg/dl
Case presentation
Investigations cont …

  C. URINE FOR RME:
                        Color              –   Straw
                        Appearance         –   Clear
                        Albumin            –   absent
                        Epithelial cells   –   (2-4) / HPF
                        RBC                –   Nil
                        Pus Cells          –   (1-2) /HPF




  D. PLAIN X-RAY OF CHEST P/A VIEW:                    Normal
Case presentation
Investigations cont …



    F. USG OF WHOLE ABDOMEN (01/09/2009)

    Liver:    An echogenic area with surrounding halo is seen in
              posterior superior quadrant of right lobe of liver near
              gall bllader.
    All other viscera were normal and no lymphadenopathy or
    ascites

    Impression: suggestive of SOL of liver.
                     most possibly 2ndary
Case presentation
Investigations cont …

              G. Proctoscopic biopsy:
                       Proctoscopic biopsy was taken from the
                        annular rectal growth and after proper
                        preservation and labelling was sent for
                        hislogical examiantion.
                       Histological examination revealed –
                        adenocarcinoma, moderately differentiated.

              ( Colonoscopy        & CEA – not done)
Case presentation
15. TREATMENT

 Plan Of Treatment :
 Abdominoperineal excision
 Ratinonale: The growth was 3 cm from the anal verge and
 involving the sphincter
 Pre Operative Preparation :
 The pt. was made fit for general anesthesia with proper
 diet, nutrition , blood transfusion and adequate glycaemic control
 with inj. insulin and control of BP with anti- hypertensive and
 required investigations were done.
 Two units of fresh human blood were arranged for operation.
Case presentation
15. TREATMENT

 Bowel preparation:
      NPO from 10 pm (day before surgery)
      Inf. Hartman’s solution 1000 ml: IV @ 10 drop/min
      Inj. Ciprofloxacin 500 mg: IV bd
      Inj. Metronidazole 400 mg: IV tds
      Inj. Mannitol: 250 ml orally at 5pm
                    125 ml orally if necessary at 6 pm
      Enema Simplex: at 10 pm (day before surgery)
                       at 7 am ( on day of surgery)
 Consent :
1.       An informed written consent was taken from the pt. and his wife for
         abdomenoperineal excision along with permanent colostomy in left iliac
         fossa under general anesthesia.
2.        Patient and his wife was briefed about management of colostomy.
Case presentation
Treatment ( Surgical management ) cont …

                         OPERATION NOTE :

 Venue                           : General OT in SBMCH, Barisal.
 Date                          : 25/10/2009.
 Time                          : 11:30 am.
 Indication                      : carcinoma rectum.
 Name of operation           : abdomenoperineal excision
                              with permanent end colostomy.
 Name of anesthesia         : GA with endotracheal intubation.
 Name of Surgeon                 : Prof. A M S M Sharfuzzaman.
                             FCPS, MRCS (Edin)

                             Dr. Zahurul Haq FCPS (surgery)
                             Assistant Professor, Surgery
Case presentation
Treatment ( operation note ) cont …


 Position:
   Trendelenburg lithotomy position (with urinary catheter in
   situ)

 Incision:
         Abdominal surgeon – made a midline incision
         Perineal surgeon – made an elliptical incision between
         the coccyx and the central perineal point, around anus.
Case presentation
15. TREATMENT
  Procedure and findings       :
 With all aseptic precaution abdominal surgeon opened the
  abdomen through a midline incision. Liver and peritoneal
  cavity was assessed for any metastasis. Which was not found.
  So decision for curative Total mesorectal excision was taken
 Coils of small intestine was packed using mops to keep them
  away from the pelvic cavity. Retractors were used for proper
  exposure and sigmoid colon was freed by dividing the
  peritoneal reflection on the left side.
 The sigmoid colon was mobilized to the midline on its
  mesentry, and the left ureter and testicular vessels were
  identified and secured.
Case presentation
Treatment ( operation note ) cont …


 The mesocolon was divided at the site of proposed
  division of the colon and the inferior mesenteric artery
  ligated and divided distal to the first sigmoidal branch.
 Then the sigmoid colon at this point, is cut in between the
  intestinal clumps. Peritoneal fold over the rectosigmoid
  junction is divided to make it free. Middle rectal artery
  was ligated and divided. Median sacral artery were also
  secured. Sigmoid colon and rectum were freed from the
  pelvic cavity by both sharp and blunt dissection
  preserving the nerves of sacral plexus.
Case presentation
Treatment ( operation note ) cont …
 The perineal surgeon closed the anus with purse-string sutures
  using no. 1 cutting body silk.
 An elliptical shaped incision around the anus through the
  transverse perineal muscle anteriorly and levator ani muscle
  posteriorly and keeping the dissection line away from the
  prostate and urethra through Denonviller’s fascia.
 The left forefinger was insinuated into the levator ani, which was
  divided lateral to the finger, first on one side then on another
  side. Dissecting the Waledeyer’s fascia by diathermy and
  scissors, then contact was made with the abdominal surgeon.
  The apex of the skin anterior to the anus was grasped by artery
  forceps acting as a retractor. The wound was deepened by
  dissection by diathermy, scissors and gauge. When the catheter
  within the membranous urethra was felt, a plane of cleavage was
  formed between the rectum and prostate.
Case presentation
Treatment ( operation note ) cont …
 Denonviller’s fascia was divided after which the rectum
  was separated from the prostate. The abdominal surgeon
  freed the rectum from pelvic cavity. Whole of the
  anus, rectum and part of the sigmoid colon was drawn
  downwards and removed through the perineal wound.
 Haemostasis was done using diathermy, ligation and hot
  mopping. The perineal muscle was closed in layers with
  1/0 round body vicryl. Skin was closed with 2/0 cutting
  body silk. A drain was applied in the peritoneal cavity
  through the right ischeorectal fossa.
Case presentation
Treatment ( operation note ) cont …
 A permanent end colostomy was made 2.5 cm above the
  left spino-umbilical line.
 Peritoneal defects were sutured with 1/0 round body
  catgut. Abdomen was closed in layers. Peritoneum
  sutured by 1/0 catgut ,Linea alba by no. 1 prolene and skin
  by 2/0 silk.
 Sterile dressings were placed on the abdominal and
  perineal wound
Video of APER
Case presentation
Treatment ( operation note ) cont …
16. Postoperative period:
   NPO for 48 hours then food was given orally
   IV fluid for 48 hours
   IV antibiotic for 5 days
   IM analgesic for 48 hours then switched to oral formulation
   Colostomy was managed by colostomy bag
   Catheter – removed on 5th POD
   Perineal wound infection was noticed on 6th POD, stitches
    were removed , and wound was managed by Seitz bath
Figure showing :
midline incision mark
colostomy bag in place (covering
The colostomy in left iliac fossa)
Figure showing:
Gap in the perineal wound
Which was later on managed by
Seitz bath
Case presentation
Treatment ( operation note ) cont …

18. DISCHARGE AND ADVICE :
  Patient was advised to contact with radiotherapy
  department on 15th post operative day for further
  oncological surveillance.
THANK YOU ALL

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Carcinoma rectum

  • 1. Carcinoma Rectum A CASE PRESENTATION DR. JOY ZAKHARIA RAB ASSISTANT REGISTRAR SURGERY UNIT – I SBMCH,BARISAL.
  • 2. Mr. Aiub Ali 65 yrs Before operation
  • 3. Case presentation 1. PARTICULARS OF THE PATIENT: Name: Ayub Ali Date Admission: 29/08/09 Father’s name: Late Abdul Ali Hospital : SBMCH Age: 65 years. Department : SU-I Sex: male. Ward : 11 Marital status: married . Bed : 16 Religion: Islam. Occupation: farmer Social status : Poor Address: Kawer Char Barisal Sadar Dist- Barisal
  • 4. Case presentation 2. PRESENTING COMPLAINTS : Weakness for 6 months Feeling of incomplete defecation for 3 months Pain or discomfort during defecation for same duration Per rectal bleeding for 3 months
  • 5. Case presentation 3. HISTORY OF PRESENT ILLNESS: According to the statement of the patient he was quite well 6 months back. Since then he developed nausea and found himself unwilling to do any daily activities due to unusual weakness. He went to village doctor who advised him some vitamin tablets but these were not very fruitful to overcome his weakness or nausea. Then after 3 months he noticed passing of hard stool followed by small amount of bleeding at end of defecation.
  • 6. Case presentation 3. HISTORY OF PRESENT ILLNESS: He ignored this bleeding and thought this may be due to constipation. But after few days he felt abdominal cramp which made him to get up early in the morning due to urge for defecation but only some amount of muciod watery stool came out which could not satisfy his defecation urge, as well as passage of rectal bleeding didn’t stop. And for last 15 days rectal bleeding worsened so he came to our hospital for better management.
  • 7. Case presentation 4. HISTORY OF PAST ILLNESS: HTN. 5. PERSONAL HISTORY: Diet habit : He took high fibre and roughage Vegetables almost daily Less animal fat Red meat usually once in a month Nonsmoker Nonalcoholic . 6. FAMILY HISTORY: None of His family members were suffering from this type of disease
  • 8. Case presentation 7. DRUG HISTORY: Anti-hypertensive: Tenoren Amdocal Syp. Antacid 8. HISTORY OF IMMUNIZATION: Not Completed.
  • 9. Case presentation 9. GENERAL EXAMINATION: Appearance: ill looking Anemia : present Height : 5 ft. 2 inches Jaundice : absent. Weight : 50 kg. Edema : absent. Body build : Below average. Pulse : 80/min. Decubitus : on patient’s choice. B.P :160/100mm/Hg. Dehydration: absent Temp. : 98`F Enlarged lymph node: absent. Nutrition : below average. RR : 22 breaths/min.
  • 10. Case presentation 10. SYSTEMIC EXAMINATION: THE ABDOMEN A. INSPECTION: Shape : Scaphoid Flanks : not full. Umbilicus : normal, centrally placed. Visible vein : absent. Visible pulsation : absent. Visible peristalsis : absent. Visible swelling : absent. Hernial orifices : intact. Scar : absent.
  • 11. Case presentation The Abdomen cont ... B. PALPATION: 1. SUPERFICAL PALPATION: Local temperature : not raised. Tenderness : absent. Muscle guard/Rigidity : absent 2. DEEP PALPATION: Liver : not enlarged. Gallbladder : non palpable. Spleen : non palpable . Kidneys : kidneys were nonballotable.
  • 12. Case presentation The Abdomen cont ... C. PERCUSSION : Percussion note : Normal. D. AUSCULTATION : Bowel sound : normal. E. DRE FINDINGS : an annular growth encircling the whole circumference of the rectum which was hard in consistency with irregular margin associated with multiple small polypoid lesion around the growth which seems to be fixed with the surrounding muscles and involving the anal sphincter was found about 3 cm from the anal verge.
  • 13. Case presentation 11. OTHER SYSTEMS EXAMINATION : Cardiovascular system : normal. Respiratory system : normal. Nervous system : normal. Genito Urinary System : normal.
  • 14. Case presentation 12. CLINICAL DIAGNOSIS: Carcinoma of rectum
  • 15. Case presentation 13. INVESTIGATIONS : A. COMPLETE BLOOD COUNT:  Total Count : 8000/ cmm of blood  Differential Count : Neutrophil – 57% Lymphocyte count – 37% Mono cyte- 01% Eosinophil – 05% Basophil – 00%  Hb% : 50%.  ESR : 40 mm in 1st hour. (anaemia was corrected by 2 unit blood transfusion) B. BLOOD FOR RBS AND SERUM CREATININE: RBS – 310 mg/dl 112 mg/dl after control with inj. insulin Creatinine – 0.9mg/dl
  • 16. Case presentation Investigations cont … C. URINE FOR RME: Color – Straw Appearance – Clear Albumin – absent Epithelial cells – (2-4) / HPF RBC – Nil Pus Cells – (1-2) /HPF D. PLAIN X-RAY OF CHEST P/A VIEW: Normal
  • 17. Case presentation Investigations cont … F. USG OF WHOLE ABDOMEN (01/09/2009) Liver: An echogenic area with surrounding halo is seen in posterior superior quadrant of right lobe of liver near gall bllader. All other viscera were normal and no lymphadenopathy or ascites Impression: suggestive of SOL of liver. most possibly 2ndary
  • 18. Case presentation Investigations cont … G. Proctoscopic biopsy:  Proctoscopic biopsy was taken from the annular rectal growth and after proper preservation and labelling was sent for hislogical examiantion.  Histological examination revealed – adenocarcinoma, moderately differentiated. ( Colonoscopy & CEA – not done)
  • 19. Case presentation 15. TREATMENT Plan Of Treatment : Abdominoperineal excision Ratinonale: The growth was 3 cm from the anal verge and involving the sphincter Pre Operative Preparation : The pt. was made fit for general anesthesia with proper diet, nutrition , blood transfusion and adequate glycaemic control with inj. insulin and control of BP with anti- hypertensive and required investigations were done. Two units of fresh human blood were arranged for operation.
  • 20. Case presentation 15. TREATMENT  Bowel preparation:  NPO from 10 pm (day before surgery)  Inf. Hartman’s solution 1000 ml: IV @ 10 drop/min  Inj. Ciprofloxacin 500 mg: IV bd  Inj. Metronidazole 400 mg: IV tds  Inj. Mannitol: 250 ml orally at 5pm 125 ml orally if necessary at 6 pm  Enema Simplex: at 10 pm (day before surgery) at 7 am ( on day of surgery)  Consent : 1. An informed written consent was taken from the pt. and his wife for abdomenoperineal excision along with permanent colostomy in left iliac fossa under general anesthesia. 2. Patient and his wife was briefed about management of colostomy.
  • 21. Case presentation Treatment ( Surgical management ) cont … OPERATION NOTE : Venue : General OT in SBMCH, Barisal. Date : 25/10/2009. Time : 11:30 am. Indication : carcinoma rectum. Name of operation : abdomenoperineal excision with permanent end colostomy. Name of anesthesia : GA with endotracheal intubation. Name of Surgeon : Prof. A M S M Sharfuzzaman. FCPS, MRCS (Edin) Dr. Zahurul Haq FCPS (surgery) Assistant Professor, Surgery
  • 22. Case presentation Treatment ( operation note ) cont …  Position: Trendelenburg lithotomy position (with urinary catheter in situ)  Incision: Abdominal surgeon – made a midline incision Perineal surgeon – made an elliptical incision between the coccyx and the central perineal point, around anus.
  • 23. Case presentation 15. TREATMENT Procedure and findings :  With all aseptic precaution abdominal surgeon opened the abdomen through a midline incision. Liver and peritoneal cavity was assessed for any metastasis. Which was not found. So decision for curative Total mesorectal excision was taken  Coils of small intestine was packed using mops to keep them away from the pelvic cavity. Retractors were used for proper exposure and sigmoid colon was freed by dividing the peritoneal reflection on the left side.  The sigmoid colon was mobilized to the midline on its mesentry, and the left ureter and testicular vessels were identified and secured.
  • 24. Case presentation Treatment ( operation note ) cont …  The mesocolon was divided at the site of proposed division of the colon and the inferior mesenteric artery ligated and divided distal to the first sigmoidal branch.  Then the sigmoid colon at this point, is cut in between the intestinal clumps. Peritoneal fold over the rectosigmoid junction is divided to make it free. Middle rectal artery was ligated and divided. Median sacral artery were also secured. Sigmoid colon and rectum were freed from the pelvic cavity by both sharp and blunt dissection preserving the nerves of sacral plexus.
  • 25. Case presentation Treatment ( operation note ) cont …  The perineal surgeon closed the anus with purse-string sutures using no. 1 cutting body silk.  An elliptical shaped incision around the anus through the transverse perineal muscle anteriorly and levator ani muscle posteriorly and keeping the dissection line away from the prostate and urethra through Denonviller’s fascia.  The left forefinger was insinuated into the levator ani, which was divided lateral to the finger, first on one side then on another side. Dissecting the Waledeyer’s fascia by diathermy and scissors, then contact was made with the abdominal surgeon. The apex of the skin anterior to the anus was grasped by artery forceps acting as a retractor. The wound was deepened by dissection by diathermy, scissors and gauge. When the catheter within the membranous urethra was felt, a plane of cleavage was formed between the rectum and prostate.
  • 26. Case presentation Treatment ( operation note ) cont …  Denonviller’s fascia was divided after which the rectum was separated from the prostate. The abdominal surgeon freed the rectum from pelvic cavity. Whole of the anus, rectum and part of the sigmoid colon was drawn downwards and removed through the perineal wound.  Haemostasis was done using diathermy, ligation and hot mopping. The perineal muscle was closed in layers with 1/0 round body vicryl. Skin was closed with 2/0 cutting body silk. A drain was applied in the peritoneal cavity through the right ischeorectal fossa.
  • 27. Case presentation Treatment ( operation note ) cont …  A permanent end colostomy was made 2.5 cm above the left spino-umbilical line.  Peritoneal defects were sutured with 1/0 round body catgut. Abdomen was closed in layers. Peritoneum sutured by 1/0 catgut ,Linea alba by no. 1 prolene and skin by 2/0 silk.  Sterile dressings were placed on the abdominal and perineal wound
  • 29. Case presentation Treatment ( operation note ) cont … 16. Postoperative period:  NPO for 48 hours then food was given orally  IV fluid for 48 hours  IV antibiotic for 5 days  IM analgesic for 48 hours then switched to oral formulation  Colostomy was managed by colostomy bag  Catheter – removed on 5th POD  Perineal wound infection was noticed on 6th POD, stitches were removed , and wound was managed by Seitz bath
  • 30.
  • 31. Figure showing : midline incision mark colostomy bag in place (covering The colostomy in left iliac fossa)
  • 32. Figure showing: Gap in the perineal wound Which was later on managed by Seitz bath
  • 33. Case presentation Treatment ( operation note ) cont … 18. DISCHARGE AND ADVICE : Patient was advised to contact with radiotherapy department on 15th post operative day for further oncological surveillance.