Leptospira

Leptospira G.HARIPRASAD M.Sc.,(Med micro),M.phil., Lecturer in Microbiology Department of Microbiology Thoothukudi Govt. Medical College Thoothukudi LEPTOSPIRA

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Classification ,[object Object],[object Object],[object Object],[object Object]

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Leptospira interrogans-Pathogenicity ,[object Object],The primary reservoir is rodents because, once infected, they shed the organisms for life. ANIMAL RESERVOIR FOR LEPTOSPIRA RODENT

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WEIL’S DISEASE ,[object Object],[object Object],[object Object],[object Object]

Laboratory diagnosis ,[object Object],[object Object],[object Object],[object Object]

DARK-GROUND MICROSCOPY Gold standard method for detection of spirochetes including Leptospira

CULTURE ,[object Object],[object Object],[object Object],[object Object]

ANIMAL INOCULATION ,[object Object],[object Object]

SEROLOGICAL TESTS ,[object Object],[object Object],[object Object],[object Object],[object Object]

SCREENING TEST ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Serotype specific tests ,[object Object],[object Object],[object Object]

[object Object],[object Object],[object Object],[object Object],PROPHYLAXIS: Rodent control Disinfection of water Wearing of protective clothes No vaccines!!!! Natural immunity develops after infection with corresponding serotype

Leptospira

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Leptospira