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EVERYONE
IMAGING ANATOMY OF
OESOPHAGUS
DR.Sateesh kumar
Primary D.N.B
KMIO
Introduction
Embryology
Gross Anatomy
Blood, Nervous supply
 lymphatic drainage
Physiology of
swallowing(oesophageal
phase)
Imaging Modalities
Conclusion
Introduction:
The esophagus serves as a
conduit between the
pharynx and the stomach .
 It begins at the
cricopharyngeus (c5-C6)
 passes through the
diaphragm to join the
cardia of stomach (D10)
 Length 23-37 cms
correlates with
individual's height and it is
usually longer in men than
in women.
Normal wall Thickness:
adequately distended: 3mm
incompletely distended:5mm
A-P diameter <16mm
Lateral diameter <24mm
New born :
length: 8-10cms
starts at c4-c5 up to T9
Anatomically divided
into three parts
Cervical(jn to notch)
4-5cms
Thoracic(notch to
hiatus)
abdominal
Functionally divided
into
upper esophageal
sphincter
esophageal body
lower esophageal
sphincter
UES
3 cm long zone of increased pressure at upper end
of esophagus
Relaxes with swallowing – normally remains
closed (prevents swallowing of air with
inspiration)
Located at the C5-C6 level
same as criopharyngeus muscle
LES (functional sphincter)
3-5 cm zone of increased pressure at lower end of
esophagus
Relaxes with swallowing
Contracts thereafter in sequence with transmitted
pressure increases – prevents reflux
Sphincter tone provided by intrinsic myogenic
activity
Sphincter relaxation due to neural activity
Esophagogastric Junction Definitions
The mucosal junction is marked by irregular
interdigitations, hence the term ‘Z line’. (ora serrata
or Z line) – most clinically practical
Point at which tubular esophagus joins gastric pouch
Junction of esophageal circular muscle layer with
oblique sling fibers of stomach (loop of Willis or
collar of Helvetius)
The gastro-oesophageal junction is found
constantly 40 cm distance from the incisor teeth.
Embryology:
Foregut
Intraembryonic part of
yolksac
10th
week single
esophageal lumen with
a superficial layer of
ciliated epithelial cells
4th month - stratified
squamous
epithelium except
upper n lower ends
 primitive foregut endoderm is the origin for both the
future esophageal epithelium and submucosal glands.
smooth muscle ,- mesenchyme of the somites
surrounding the foregut.
 striated muscle-mesenchyme of the branchial arches
4, 5, and 6. vagus 5th
RLN 6th
.
Histology:
The wall of the oesophagus comprises four layers
1. The outer fibrous coat(Adventitia)
2. Muscle layer with outer longitudinal and inner circular
fibers
3. Sub mucosa
4. Mucosa.
The mucosal lining of the oesophagus is stratified
squamous epithelium throughout its length, changing to
columnar epithelium only at the gastro-oesophageal
junction
Unlike the remainder of the GI tract, the esophagus does
not have a serosal layer, thus permitting rapid
dissemination of infection and tumor
Striated muscle predominates in the upper
esophagus, with smooth muscle in the lower two
thirds of the esophagus.
 The transition from striated to smooth muscle varies
but usually occurs at the level of the aortic arch.
Course & Relations:
Cervical oesophagus:
Anteriorly: trachea
Posteriorly: vertebral
column
Laterally: carotid sheath
Thyroid
Course & Relations
At the thoracic inlet,- it
lies slightly to the left of
midline
At the mid chest -
closely apposes the left
mainstem bronchus and
the pericardium of the
left atrium
Distally lies anterior to
the descending aorta to
the left of midline as it
enters its diaphragmatic
hiatus.
Course & Relations
 The esophagus abuts the pleura on the right but is
relatively protected from the left pleural space by the
intervening aorta.
As a result, processes involving the mid-thoracic
esophagus tend to spread into the right pleural space.
On CT, there may be small collections of air in the
esophageal lumen, but the presence of fluid or a
luminal caliber greater than 10 mm is abnormal and
suggests obstruction or a motility disorder
Oesophageal impressions: (constrictions)
Cervical : cricoid
Thoracic : Arch of aorta, left main bronchus,left
atrium.
Abdominal: oesophageal hiatus
Anatomy – Blood Supply
Cervical – inferior thyroid
arteries
Thoracic – 4-6 aortic
esophageal arteries and
branches of left bronchial
arteries
Abdominal – left gastric
artery and inferior phrenic
artery
Rich interconnecting
submucosal arterial plexus
– runs longitudinally
Venous Drainage
Subepithelial channels
Periesophageal plexus
Cervical drainage –
inferior thyroid veins
Thoracic drainage –
azygos/hemiazygos
veins
Abdominal drainage –
left gastric vein
Anatomy – Lymphatic Drainage
Vessels run
longitudinally, then
penetrate wall to enter
regional nodes
Cervical – lt
supraclavicular
Thoracic – tracheal,
tracheobronchial,
posterior mediastinal,
diaphragmatic
Abdominal – celiac axis
Esophagus Innervation
. A rich network of intrinsic neurons capable of
producing secondary peristalsis is found in the
submucosa and between the circular and
longitudinal muscle layers.
 This network communicates to the central
nervous system via the vagi(parasympathetic) and
sympathetic
 Cervical: from superior and inferior cervical
sympathetic ganglia
Thorax: from upper thoracic and splanchnic
nerves
Abdominal: from celiac ganglion
Physiology of Swallowing
Primary peristalsis – progressive, triggered by
voluntary swallowing
Secondary peristalsis – progressive, generated by
distention or irritation usually from bolus not
traversing through the esophagus.propels
remaining bolus distally.
Tertiary peristalsis – nonprogressive
(simultaneous) and uncoordinated, after
voluntary or spontaneously between swallows –
responsible for “corkscrew” appearance of spasm
of Barium Swallow
Imaging modalities
Plain radiography
Contrast Swallow
USG
CT
MRI
PET CT
Radionuclide scan
Plain Radiography:
 Per se plain chest xray
is not modality for
imaging Normal
oesophagus
 A chest radiograph
may give clue regarding
perforation ,foreign
bodies, achalasia etc.
Contrast swallow
Contrast medium::
Single contrast
1. Barium sulphate 80% suspension
2. Gastrografin
3. Gastromiro (Iopamidol) non ionic water
soluble
Gastrografin should NOT be used for the investigation of a tracheo-
oesophageal fistula or when aspiration is a possibility.
Barium should NOT be used if perforation is suspected.
Double contrast study: 200-250% high density , low
viscocity 15-20ml . Effervescent powder(or NG Tube)
is given with another mouth full of barium.
Erect>prone>supine
Medications: Buscopan or glucagon for hypotonia for
longer retention (not for assessment of motility
disorders)
Positions: RAO ,LAO, Frontal,Lateral in erect
Motility disorders(prone swallow)
Severe dysphagia?? 5ml diluted barium initially further filming n
contrast based on abnormality observed
Barium has superior contrast qualities and unless
there are specific contraindications, its use (rather
than water-soluble agents) is preferred.
Rapid serial radiography (2 frames per s) or video
recording may be required for assessment of the
laryngopharynx and upper oesophagus during
deglutition
The patient is in the erect RAO position to throw the
oesophagus clear of the spine.
 An ample mouthful of barium is swallowed, and spot
films of the upper and lower oesophagus are taken.
.
If rapid serial radiography is required, it may be
performed in the right lateral, RAO and PA positions
AP or PA Projection
Pt. supine or prone
Center midsagittal
plane to cassette
Bottom of cassette
should be placed just
below tip of xyphoid
Pt. drinks contrast
before exposure and
continues drinking
during exposure
Structures Shown/Film Evaluation
Entire barium filled
esophagus from lower
neck to stomach
Barium should be
sufficiently penetrated
Surrounding structures
should be visible, not
overpenetrated
No rotation on AP, PA, or
lateral projections
Esophagus should be
displayed between heart
and spine on oblique
projections
Lateral Projection
Place pt in lateral
position
Center midcoronal
plane to cassette
Bottom of cassette
below xyphoid process
Pt must drink
continuously before
and during exposure
RPO VIEW
LATERAL VIEW
Tertiary peristalisis
Primary follows
Bulbous distention of
the distal esophagus is
called the vestibule and
corresponds to the
manometrically-defined
lower esophageal
sphincter.

This distention is best
demonstrated by breath
holding in inspiration or
a Valsalva maneuver.
Do not mistake this for a
hiatal hernia.
USG:
Cervical esophagus –
can be seen posterior to
Left lobe of thyroid in
routine usg neck
Linear probe : 7.5-
10MHz
USG:
GE-JUNCTION can be
visualised in trans-
abdominal sonography
Curvilinear probe:
3-5Mhz
Endoscopic USG:
Evolved as the imaging
modality of choice for
entire oesophagus.
Helps in visualising wall
layers of oesophagus
thus in perfect T-
staging( superior to CT)
Helps in taking needle
biopsy of suspected
growth and suspicious
surrounding
lymphnodes.
EUSG PROBES:
Standard EUS(S-EUS)
Probes combine
endoscopy with usg
7.5-12 MHz
Radial , linear based on
plane of scanning
E-Usg probes
Catheter USG (C-Usg
probes)
High resolution
15-30MHz
Advantages:
Technically ease
Short imaging time
Lack of compression
effect on small tumors A-MINI-PROBE
B.MINIPROBE WITH BALLOON SHEATH
C.BLIND ESOPHAGOPROBE
Using conventional
imaging frequencies,
the gastrointestinal
wall is displayed as 5
layers of alternating
black and white echo-
layers by endoscopic
ultrasound
S-EUS- 5layered wall
Inner(1)-outer(5)
 1st layer -bright (hyper-echoic)
- superficial mucosa.
 2nd (dark, hypoechoic)- deep
mucosa.
 3r d (hyperechoic)-
submucosa and the acoustic
interface between the
submucosa and the muscularis
propria.
 4th (hypoechoic) – muscularis
propria
 5th layer corresponds to the
adventitia
C-EUSG-9 Layered wall
 Layers 1-4 represent the
mucosa.
1,2 – epithelium
3- lamina propria,
4- muscularis mucosa.
5-submucosa.
6-8proper muscle layers
6- circular muscle
 7- connective tissue and
interface,
8-longitudinal muscle.
9- adventitia
CT-Protocol
Patient position: supine with arms elevated above
level of head
Topogram position: AP 1 inch below chin to
umbilicus
Mode : Helical CT with single breath hold, thus
reducing breathing and cardiac artifact
Scan orientation: caudocranial.
starting point: Imaginary line joining both cp angles
end point: 1cm above apex of lung
 High-density or positive oral contrast material
swallowed directly before CT is helpful in delineating
the esophageal lumen.
Scanning is performed during the portal venous
phase and intravenous contrast administered at a rate
of 2 to 4 mL/sec.
 Slice thickness should be no more than 5 mm
throughout the chest.
In patients with suspected esophageal varices, water
is used as a negative contrast agent combined with
intravenous contrast.
A positive oral contrast agent combined with
intravenous contrast can obscure submucosal
vascular structures.
Multiplanar reformatted images may also be helpful,
particularly in the staging of esophageal cancer.
CT has advantage over mri in detecting lymohnodes
with more accuracy
MRI
The advent of fast, breath-hold MR sequences has
increased the utility of MR in evaluation of the GI
tract.
 But there is still role for MR imaging in evaluation of
the esophagus is limited.
 Cardiac gating must be incorporated, and coverage of
the entire esophagus in a single breath-hold sequence
remains problematic .
T1 post GAD
PET-CT: For picking metastasis and extent of spread
of malignancy with in the esophagus
Nuclear medicine: Prime role for assessing
oesophageal motility disorders and reflux disease
especially in young children.
Endoscopy : Is now the investigation of choice for
evaluating as well as obtaining biopsy at the same
setting. However lack of spatial resolution and in
ability to look out side the lumen are the limitations.
conclusion
Chest xray - no/limited role in evaluating oesophagus.
Ba. Swallow is most useful modality in evaluating
oesophageal disorders
 Normal variants in barium swallow should not
be misinterpreted
Endoscopic Usg is imaging modality of choice for T-
staging of oesophageal cancer and to check
extraluminal contiguous extension
CT scan is THE imaging modality for evaluating
extraluminal disease and nodal disease in carcinoma.
MRI has limited role in evaluating oesophageal
disease
Radionucleotide scans are useful in motility disorders
Thank You
Oesophagus ppt for ss
Oesophagus ppt for ss

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Oesophagus ppt for ss

  • 2. IMAGING ANATOMY OF OESOPHAGUS DR.Sateesh kumar Primary D.N.B KMIO
  • 3. Introduction Embryology Gross Anatomy Blood, Nervous supply  lymphatic drainage Physiology of swallowing(oesophageal phase) Imaging Modalities Conclusion
  • 4. Introduction: The esophagus serves as a conduit between the pharynx and the stomach .  It begins at the cricopharyngeus (c5-C6)  passes through the diaphragm to join the cardia of stomach (D10)  Length 23-37 cms correlates with individual's height and it is usually longer in men than in women.
  • 5. Normal wall Thickness: adequately distended: 3mm incompletely distended:5mm A-P diameter <16mm Lateral diameter <24mm New born : length: 8-10cms starts at c4-c5 up to T9
  • 6. Anatomically divided into three parts Cervical(jn to notch) 4-5cms Thoracic(notch to hiatus) abdominal Functionally divided into upper esophageal sphincter esophageal body lower esophageal sphincter
  • 7. UES 3 cm long zone of increased pressure at upper end of esophagus Relaxes with swallowing – normally remains closed (prevents swallowing of air with inspiration) Located at the C5-C6 level same as criopharyngeus muscle
  • 8. LES (functional sphincter) 3-5 cm zone of increased pressure at lower end of esophagus Relaxes with swallowing Contracts thereafter in sequence with transmitted pressure increases – prevents reflux Sphincter tone provided by intrinsic myogenic activity Sphincter relaxation due to neural activity
  • 9. Esophagogastric Junction Definitions The mucosal junction is marked by irregular interdigitations, hence the term ‘Z line’. (ora serrata or Z line) – most clinically practical Point at which tubular esophagus joins gastric pouch Junction of esophageal circular muscle layer with oblique sling fibers of stomach (loop of Willis or collar of Helvetius) The gastro-oesophageal junction is found constantly 40 cm distance from the incisor teeth.
  • 10. Embryology: Foregut Intraembryonic part of yolksac 10th week single esophageal lumen with a superficial layer of ciliated epithelial cells 4th month - stratified squamous epithelium except upper n lower ends
  • 11.  primitive foregut endoderm is the origin for both the future esophageal epithelium and submucosal glands. smooth muscle ,- mesenchyme of the somites surrounding the foregut.  striated muscle-mesenchyme of the branchial arches 4, 5, and 6. vagus 5th RLN 6th .
  • 12. Histology: The wall of the oesophagus comprises four layers 1. The outer fibrous coat(Adventitia) 2. Muscle layer with outer longitudinal and inner circular fibers 3. Sub mucosa 4. Mucosa. The mucosal lining of the oesophagus is stratified squamous epithelium throughout its length, changing to columnar epithelium only at the gastro-oesophageal junction Unlike the remainder of the GI tract, the esophagus does not have a serosal layer, thus permitting rapid dissemination of infection and tumor
  • 13. Striated muscle predominates in the upper esophagus, with smooth muscle in the lower two thirds of the esophagus.  The transition from striated to smooth muscle varies but usually occurs at the level of the aortic arch.
  • 14.
  • 15.
  • 16. Course & Relations: Cervical oesophagus: Anteriorly: trachea Posteriorly: vertebral column Laterally: carotid sheath Thyroid
  • 17. Course & Relations At the thoracic inlet,- it lies slightly to the left of midline At the mid chest - closely apposes the left mainstem bronchus and the pericardium of the left atrium Distally lies anterior to the descending aorta to the left of midline as it enters its diaphragmatic hiatus.
  • 18. Course & Relations  The esophagus abuts the pleura on the right but is relatively protected from the left pleural space by the intervening aorta. As a result, processes involving the mid-thoracic esophagus tend to spread into the right pleural space. On CT, there may be small collections of air in the esophageal lumen, but the presence of fluid or a luminal caliber greater than 10 mm is abnormal and suggests obstruction or a motility disorder
  • 19. Oesophageal impressions: (constrictions) Cervical : cricoid Thoracic : Arch of aorta, left main bronchus,left atrium. Abdominal: oesophageal hiatus
  • 20. Anatomy – Blood Supply Cervical – inferior thyroid arteries Thoracic – 4-6 aortic esophageal arteries and branches of left bronchial arteries Abdominal – left gastric artery and inferior phrenic artery Rich interconnecting submucosal arterial plexus – runs longitudinally
  • 21. Venous Drainage Subepithelial channels Periesophageal plexus Cervical drainage – inferior thyroid veins Thoracic drainage – azygos/hemiazygos veins Abdominal drainage – left gastric vein
  • 22. Anatomy – Lymphatic Drainage Vessels run longitudinally, then penetrate wall to enter regional nodes Cervical – lt supraclavicular Thoracic – tracheal, tracheobronchial, posterior mediastinal, diaphragmatic Abdominal – celiac axis
  • 23. Esophagus Innervation . A rich network of intrinsic neurons capable of producing secondary peristalsis is found in the submucosa and between the circular and longitudinal muscle layers.  This network communicates to the central nervous system via the vagi(parasympathetic) and sympathetic  Cervical: from superior and inferior cervical sympathetic ganglia Thorax: from upper thoracic and splanchnic nerves Abdominal: from celiac ganglion
  • 24. Physiology of Swallowing Primary peristalsis – progressive, triggered by voluntary swallowing Secondary peristalsis – progressive, generated by distention or irritation usually from bolus not traversing through the esophagus.propels remaining bolus distally. Tertiary peristalsis – nonprogressive (simultaneous) and uncoordinated, after voluntary or spontaneously between swallows – responsible for “corkscrew” appearance of spasm of Barium Swallow
  • 25. Imaging modalities Plain radiography Contrast Swallow USG CT MRI PET CT Radionuclide scan
  • 26. Plain Radiography:  Per se plain chest xray is not modality for imaging Normal oesophagus  A chest radiograph may give clue regarding perforation ,foreign bodies, achalasia etc.
  • 27. Contrast swallow Contrast medium:: Single contrast 1. Barium sulphate 80% suspension 2. Gastrografin 3. Gastromiro (Iopamidol) non ionic water soluble Gastrografin should NOT be used for the investigation of a tracheo- oesophageal fistula or when aspiration is a possibility. Barium should NOT be used if perforation is suspected.
  • 28. Double contrast study: 200-250% high density , low viscocity 15-20ml . Effervescent powder(or NG Tube) is given with another mouth full of barium. Erect>prone>supine Medications: Buscopan or glucagon for hypotonia for longer retention (not for assessment of motility disorders) Positions: RAO ,LAO, Frontal,Lateral in erect Motility disorders(prone swallow) Severe dysphagia?? 5ml diluted barium initially further filming n contrast based on abnormality observed
  • 29. Barium has superior contrast qualities and unless there are specific contraindications, its use (rather than water-soluble agents) is preferred. Rapid serial radiography (2 frames per s) or video recording may be required for assessment of the laryngopharynx and upper oesophagus during deglutition
  • 30. The patient is in the erect RAO position to throw the oesophagus clear of the spine.  An ample mouthful of barium is swallowed, and spot films of the upper and lower oesophagus are taken. . If rapid serial radiography is required, it may be performed in the right lateral, RAO and PA positions
  • 31. AP or PA Projection Pt. supine or prone Center midsagittal plane to cassette Bottom of cassette should be placed just below tip of xyphoid Pt. drinks contrast before exposure and continues drinking during exposure
  • 32. Structures Shown/Film Evaluation Entire barium filled esophagus from lower neck to stomach Barium should be sufficiently penetrated Surrounding structures should be visible, not overpenetrated No rotation on AP, PA, or lateral projections Esophagus should be displayed between heart and spine on oblique projections
  • 33. Lateral Projection Place pt in lateral position Center midcoronal plane to cassette Bottom of cassette below xyphoid process Pt must drink continuously before and during exposure
  • 36.
  • 37. Bulbous distention of the distal esophagus is called the vestibule and corresponds to the manometrically-defined lower esophageal sphincter.  This distention is best demonstrated by breath holding in inspiration or a Valsalva maneuver. Do not mistake this for a hiatal hernia.
  • 38. USG: Cervical esophagus – can be seen posterior to Left lobe of thyroid in routine usg neck Linear probe : 7.5- 10MHz
  • 39. USG: GE-JUNCTION can be visualised in trans- abdominal sonography Curvilinear probe: 3-5Mhz
  • 40. Endoscopic USG: Evolved as the imaging modality of choice for entire oesophagus. Helps in visualising wall layers of oesophagus thus in perfect T- staging( superior to CT) Helps in taking needle biopsy of suspected growth and suspicious surrounding lymphnodes.
  • 41. EUSG PROBES: Standard EUS(S-EUS) Probes combine endoscopy with usg 7.5-12 MHz Radial , linear based on plane of scanning
  • 42.
  • 43. E-Usg probes Catheter USG (C-Usg probes) High resolution 15-30MHz Advantages: Technically ease Short imaging time Lack of compression effect on small tumors A-MINI-PROBE B.MINIPROBE WITH BALLOON SHEATH C.BLIND ESOPHAGOPROBE
  • 44. Using conventional imaging frequencies, the gastrointestinal wall is displayed as 5 layers of alternating black and white echo- layers by endoscopic ultrasound
  • 45. S-EUS- 5layered wall Inner(1)-outer(5)  1st layer -bright (hyper-echoic) - superficial mucosa.  2nd (dark, hypoechoic)- deep mucosa.  3r d (hyperechoic)- submucosa and the acoustic interface between the submucosa and the muscularis propria.  4th (hypoechoic) – muscularis propria  5th layer corresponds to the adventitia
  • 46. C-EUSG-9 Layered wall  Layers 1-4 represent the mucosa. 1,2 – epithelium 3- lamina propria, 4- muscularis mucosa. 5-submucosa. 6-8proper muscle layers 6- circular muscle  7- connective tissue and interface, 8-longitudinal muscle. 9- adventitia
  • 47.
  • 48. CT-Protocol Patient position: supine with arms elevated above level of head Topogram position: AP 1 inch below chin to umbilicus Mode : Helical CT with single breath hold, thus reducing breathing and cardiac artifact Scan orientation: caudocranial. starting point: Imaginary line joining both cp angles end point: 1cm above apex of lung  High-density or positive oral contrast material swallowed directly before CT is helpful in delineating the esophageal lumen.
  • 49. Scanning is performed during the portal venous phase and intravenous contrast administered at a rate of 2 to 4 mL/sec.  Slice thickness should be no more than 5 mm throughout the chest. In patients with suspected esophageal varices, water is used as a negative contrast agent combined with intravenous contrast.
  • 50. A positive oral contrast agent combined with intravenous contrast can obscure submucosal vascular structures. Multiplanar reformatted images may also be helpful, particularly in the staging of esophageal cancer. CT has advantage over mri in detecting lymohnodes with more accuracy
  • 51.
  • 52.
  • 53.
  • 54.
  • 55.
  • 56.
  • 57. MRI The advent of fast, breath-hold MR sequences has increased the utility of MR in evaluation of the GI tract.  But there is still role for MR imaging in evaluation of the esophagus is limited.  Cardiac gating must be incorporated, and coverage of the entire esophagus in a single breath-hold sequence remains problematic .
  • 58.
  • 60.
  • 61.
  • 62. PET-CT: For picking metastasis and extent of spread of malignancy with in the esophagus Nuclear medicine: Prime role for assessing oesophageal motility disorders and reflux disease especially in young children. Endoscopy : Is now the investigation of choice for evaluating as well as obtaining biopsy at the same setting. However lack of spatial resolution and in ability to look out side the lumen are the limitations.
  • 63.
  • 64. conclusion Chest xray - no/limited role in evaluating oesophagus. Ba. Swallow is most useful modality in evaluating oesophageal disorders  Normal variants in barium swallow should not be misinterpreted Endoscopic Usg is imaging modality of choice for T- staging of oesophageal cancer and to check extraluminal contiguous extension CT scan is THE imaging modality for evaluating extraluminal disease and nodal disease in carcinoma. MRI has limited role in evaluating oesophageal disease Radionucleotide scans are useful in motility disorders