16. Renal Tubular Injury in ATN Loss of polarity and brush border Normal epithelium with brush border
17. Cell death -apoptosis and necrosis Sloughing of dead and viable cells - luminal obstruction
18.
19. Spread and de-differentiation of viable cells Proliferation, differentiation and reestablishment of polarity Normal epithelium with brush border
20.
21.
22.
23.
24.
25.
26. present absent Metabolic bone disease present absent Anemia small normal to large Kidney size polyuria oliguria Urine output polyuria, polydipsia recent drug administration, toxin exposure,surgery/hypovolemia History Chronic Renal failure Acute renal failure