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DNA Replication
DNA Replication:
    SEMICONSERVATIVE
         MODEL
FIG 16.10
Semi-conservative


This process
is fueled
by…
nucleoside
triphosphates
DNA is made from
5’ to 3’ and it is
read from 3’-5’.
The 3’ end is the
end which
elongates (grows)
Leading & Lagging
strands
•made 5’-3’
Okazaki fragments
(are of the lagging
strand)


ENZYMES:
•Helicase (not shown)
•DNA Polymerase
•ligase
Enzymes
•Helicase
•Single strand binding
proteins
•Primase(RNA Primer)
•DNA Polymerase
•Ligase
•Nuclease and DNA
Polymerase
(both are repair
enzymes)
Repairing mistakes
Telomeres
•Unfilled gap left
at the ends of the
DNA strands due
to the use of RNA
primers
•Eventual
shortening of DNA
over time
•Dolly, cancer,
telomerase
Dna replication Lecture

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Dna replication Lecture