This document summarizes various causes and management of thrombocytopenia and bleeding disorders. It discusses evaluation and treatment of conditions that cause decreased platelet count or function such as immune thrombocytopenia, thrombotic thrombocytopenic purpura, hemophilia, von Willebrand disease, and liver disease. Treatment options include steroids, IV immunoglobulins, platelet transfusions, desmopressin, coagulation factor concentrates, cryoprecipitate, splenectomy and plasma exchange.

1. Prof.Dr.G.Sundaramurthy’s unit Dr.K.Senthamizh selvan

11. children adults Asymptomatic --------------------------- Prednisone 1-2mg/kg/d Minor purpura IVIg 1g/kg single dose ; High dose oral steroids ; Prednisone 1-2mg/kg/d ; Mucosal bleeding Hospital care ; IVIg 2g/kg over 2-5 days; High dose oral steroids ; Hospital care ; Prednisone 1-2mg/kg/d ; Life threatening bleed Hospital care ; IVIg 2g/kg over 2-5 days; High dose oral steroids ; Hospital care ; IVIg 1-2g/kg over 2-5 days ; Prednisone 1-2mg/kg/d ;