SlideShare a Scribd company logo
1 of 50
The Indispensable Forensic Science Tool DNA:
Why is DNA an Indispensable Tool Forensic Science? ,[object Object]
[object Object],[object Object],[object Object]
Its Uses ,[object Object]
The Angel of Death: Josef Menegle ,[object Object],[object Object],[object Object],[object Object]
Paternity Cases ,[object Object],1. 2. 1. 2.
Homicide or Rapes: OJ Simpson
Exoneration ,[object Object],[object Object],[object Object],[object Object]
Exoneration
What is DNA? ,[object Object],[object Object],[object Object]
James Watson & Francis Crick ,[object Object],[object Object],[object Object],[object Object]
What is DNA? ,[object Object],[object Object]
[object Object]
A T A G C C A A C C A A T A T C G G T T G G T T Replication of a single strand of DNA
DNA at Work ,[object Object],[object Object],[object Object]
How can the DNA sequence dictate the sequence for a particular protein? ,[object Object],[object Object],[object Object]
U A U C G G U U G G U U A T A G C C A A C C A A So, a DNA Sequence of:   Would have an mRNA sequence of : Use the following table to determine which of the 20 amino acids would make up this sequence.  Each group of three nucleotide bases, an RNA triplet codon, is read in order to determine which amino acid is placed in the sequence.  The sequence determines the type of protein that is produced. U A U   C G G   U U G  G U U DNA template Strand RNA Strand of Transcribed DNA
U A U C G G U U G G U U
U A U   C G G   U U G  G U U mRNA Sequence: Would result in this protein amino acid sequence Tyrosine Arginine Leucine Valine Tyrosine Arginine Leucine Valine
U A U   C G G   U U  C  G U U a one base change in the mRNA Sequence: Would result in this protein amino acid sequence U A U   C G G   U U G  G U U Tyrosine Arginine Phenylalaine Valine Tyrosine Arginine Phenylalaine Valine
II.  DNA Profiling ,[object Object],[object Object],[object Object],[object Object]
Discovery – Sir Alec Jeffreys ,[object Object],[object Object]
DNA Analysis   A New Technique –- Why Use It? ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
How Does It Work? ,[object Object],[object Object],[object Object],[object Object]
Potential Sources of DNA ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
The 2 Main Types of DNA Profiling ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
 
1.  RFLPs ,[object Object],[object Object],[object Object],[object Object]
RFLP: Electrophoresis ,[object Object],[object Object],[object Object]
RFLP: Autoradiograph
[object Object]
How unique are these profiles? ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Paternity  ,[object Object],[object Object]
Interpret the results of the following DNA fingerprints ,[object Object]
[object Object]
2.  STRs ,[object Object],[object Object],[object Object]
 
 
 
 
 
How do we get so much variation? Recall inheritance patterns...
How do we get so much variation? Recall inheritance patterns... ,[object Object],[object Object],[object Object],[object Object],[object Object]
Automated STR Test
Crime Scene Samples &  Reference Samples ,[object Object],[object Object]
Extract and Purify DNA ,[object Object]
PCR Amplification ,[object Object],[object Object]
 
Genetic Analyzer: SIZE, COLOR  & AMOUNT
Genetic Analyzer:  Capillary Electrophoresis ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Detector Window

More Related Content

What's hot

DNA fingerprinting
DNA fingerprintingDNA fingerprinting
DNA fingerprinting
santharooban
 

What's hot (20)

DNA finger printing
DNA finger printing DNA finger printing
DNA finger printing
 
Presentation dna fingerprinting
Presentation  dna fingerprintingPresentation  dna fingerprinting
Presentation dna fingerprinting
 
Dna sequencing
Dna sequencingDna sequencing
Dna sequencing
 
DNA fingerprinting
DNA fingerprintingDNA fingerprinting
DNA fingerprinting
 
Pcr primer design
Pcr primer designPcr primer design
Pcr primer design
 
dna fingerprinting powerpoint
dna fingerprinting powerpointdna fingerprinting powerpoint
dna fingerprinting powerpoint
 
DNA fingerprinting
DNA fingerprintingDNA fingerprinting
DNA fingerprinting
 
Dna finger printing
Dna finger printingDna finger printing
Dna finger printing
 
Dna fingerprinting
Dna fingerprintingDna fingerprinting
Dna fingerprinting
 
DND sequencing
DND sequencingDND sequencing
DND sequencing
 
DNA Stuctre and function
DNA Stuctre and function DNA Stuctre and function
DNA Stuctre and function
 
Pyrosequencing
PyrosequencingPyrosequencing
Pyrosequencing
 
Introduction to molecular biology
Introduction to molecular biologyIntroduction to molecular biology
Introduction to molecular biology
 
forensic molecular biology
forensic molecular biologyforensic molecular biology
forensic molecular biology
 
Genome sequencing
Genome sequencingGenome sequencing
Genome sequencing
 
DNA Fingerprinting
DNA FingerprintingDNA Fingerprinting
DNA Fingerprinting
 
Ion torrent semiconductor sequencing technology
Ion torrent semiconductor sequencing technologyIon torrent semiconductor sequencing technology
Ion torrent semiconductor sequencing technology
 
Microarray
MicroarrayMicroarray
Microarray
 
Techniques of DNA Extraction, Purification and Quantification
Techniques of DNA Extraction, Purification and QuantificationTechniques of DNA Extraction, Purification and Quantification
Techniques of DNA Extraction, Purification and Quantification
 
Forensic DNA Typing-M. Asif
Forensic DNA Typing-M. AsifForensic DNA Typing-M. Asif
Forensic DNA Typing-M. Asif
 

Viewers also liked

Forensic science powerpoint
Forensic science powerpointForensic science powerpoint
Forensic science powerpoint
keschroeder118
 
Dna fingerprinting powerpoint
Dna fingerprinting powerpointDna fingerprinting powerpoint
Dna fingerprinting powerpoint
Genevia Vincent
 
Dna fingerprinting
Dna fingerprintingDna fingerprinting
Dna fingerprinting
Saikat Saha
 
DNA FINGERPRINTING
DNA FINGERPRINTINGDNA FINGERPRINTING
DNA FINGERPRINTING
Parth Shah
 

Viewers also liked (20)

Dna forensic
Dna forensicDna forensic
Dna forensic
 
DNA FORENSIC ANALYSIS
DNA FORENSIC ANALYSISDNA FORENSIC ANALYSIS
DNA FORENSIC ANALYSIS
 
Dna profiling
Dna profilingDna profiling
Dna profiling
 
Forensic
ForensicForensic
Forensic
 
DNA Fingerprinting
DNA FingerprintingDNA Fingerprinting
DNA Fingerprinting
 
DNA Analysis
DNA Analysis DNA Analysis
DNA Analysis
 
Dna fingerprinting
Dna fingerprintingDna fingerprinting
Dna fingerprinting
 
Forensic science powerpoint
Forensic science powerpointForensic science powerpoint
Forensic science powerpoint
 
Dna fingerprinting powerpoint
Dna fingerprinting powerpointDna fingerprinting powerpoint
Dna fingerprinting powerpoint
 
Forensic Science
Forensic ScienceForensic Science
Forensic Science
 
Dna fingerprinting
Dna fingerprintingDna fingerprinting
Dna fingerprinting
 
Dna in forensics
Dna in forensicsDna in forensics
Dna in forensics
 
Dr. Carlo Ventura - DNA and Cell reprogramming
Dr. Carlo Ventura - DNA and Cell reprogramming Dr. Carlo Ventura - DNA and Cell reprogramming
Dr. Carlo Ventura - DNA and Cell reprogramming
 
Dna profiling
Dna profilingDna profiling
Dna profiling
 
FORENSIC DNA PROFILING: Strengths and Limitations
FORENSIC DNA PROFILING: Strengths and LimitationsFORENSIC DNA PROFILING: Strengths and Limitations
FORENSIC DNA PROFILING: Strengths and Limitations
 
DNA FINGERPRINTING
DNA FINGERPRINTINGDNA FINGERPRINTING
DNA FINGERPRINTING
 
J clin forensicmed 2004_11(2)82
J clin forensicmed 2004_11(2)82J clin forensicmed 2004_11(2)82
J clin forensicmed 2004_11(2)82
 
ICD10 cause of death
ICD10 cause of deathICD10 cause of death
ICD10 cause of death
 
85838994 arushi-murdar-case-english
85838994 arushi-murdar-case-english85838994 arushi-murdar-case-english
85838994 arushi-murdar-case-english
 
Predatory Deviance- murder,rape & theft
Predatory Deviance- murder,rape & theftPredatory Deviance- murder,rape & theft
Predatory Deviance- murder,rape & theft
 

Similar to Forensic Dna Me

This is good ...ANTHONY SEMINAR POWER POINT.pptx
This is good ...ANTHONY SEMINAR POWER POINT.pptxThis is good ...ANTHONY SEMINAR POWER POINT.pptx
This is good ...ANTHONY SEMINAR POWER POINT.pptx
iwegbuebubechukwu9
 

Similar to Forensic Dna Me (20)

chapter 9 - dna powerpoint for forensics
chapter 9 - dna powerpoint for forensicschapter 9 - dna powerpoint for forensics
chapter 9 - dna powerpoint for forensics
 
DNA Fingerprinting
DNA FingerprintingDNA Fingerprinting
DNA Fingerprinting
 
DNA Fingerprinting.pptx
DNA Fingerprinting.pptxDNA Fingerprinting.pptx
DNA Fingerprinting.pptx
 
Fs Ch 14
Fs Ch 14Fs Ch 14
Fs Ch 14
 
Finger print(vishvanath bilagadi)
Finger print(vishvanath bilagadi)Finger print(vishvanath bilagadi)
Finger print(vishvanath bilagadi)
 
This is good ...ANTHONY SEMINAR POWER POINT.pptx
This is good ...ANTHONY SEMINAR POWER POINT.pptxThis is good ...ANTHONY SEMINAR POWER POINT.pptx
This is good ...ANTHONY SEMINAR POWER POINT.pptx
 
DNA Profiling
DNA ProfilingDNA Profiling
DNA Profiling
 
DNA FIngerprinting.ppt
DNA FIngerprinting.pptDNA FIngerprinting.ppt
DNA FIngerprinting.ppt
 
Dna profiling
Dna profilingDna profiling
Dna profiling
 
DNA fingerprinting
DNA fingerprintingDNA fingerprinting
DNA fingerprinting
 
Role of dna fingerprinting in crimes
Role of dna fingerprinting in crimesRole of dna fingerprinting in crimes
Role of dna fingerprinting in crimes
 
Dna fingerprinting powerpoint 1
Dna fingerprinting powerpoint 1Dna fingerprinting powerpoint 1
Dna fingerprinting powerpoint 1
 
DNA Does Not Lie
DNA Does Not LieDNA Does Not Lie
DNA Does Not Lie
 
Dna
DnaDna
Dna
 
Forensic Anthropology الاستعراف
Forensic Anthropology الاستعراف Forensic Anthropology الاستعراف
Forensic Anthropology الاستعراف
 
1. dna in forensic
1. dna in forensic1. dna in forensic
1. dna in forensic
 
The DNA
The DNAThe DNA
The DNA
 
Dna fingerprinting
Dna fingerprintingDna fingerprinting
Dna fingerprinting
 
Forensic dna typing by John M Butler
Forensic dna typing by John M ButlerForensic dna typing by John M Butler
Forensic dna typing by John M Butler
 
Dna Cloning
Dna CloningDna Cloning
Dna Cloning
 

More from Bob Smullen

Topic 8: Ecology Option C Part 2
Topic 8: Ecology Option C Part 2Topic 8: Ecology Option C Part 2
Topic 8: Ecology Option C Part 2
Bob Smullen
 

More from Bob Smullen (20)

1. complete stats notes
1. complete stats notes1. complete stats notes
1. complete stats notes
 
Topic One: Cell
Topic One: CellTopic One: Cell
Topic One: Cell
 
Endocrine System
Endocrine SystemEndocrine System
Endocrine System
 
IB Biology Human Reproduction
IB Biology Human Reproduction IB Biology Human Reproduction
IB Biology Human Reproduction
 
Topic 8: Ecology Option C Part 2
Topic 8: Ecology Option C Part 2Topic 8: Ecology Option C Part 2
Topic 8: Ecology Option C Part 2
 
Topic 8: Ecology Option C Part 1
Topic 8: Ecology Option C Part 1Topic 8: Ecology Option C Part 1
Topic 8: Ecology Option C Part 1
 
Topic 7: Plant Science
Topic 7: Plant ScienceTopic 7: Plant Science
Topic 7: Plant Science
 
Topic 6: Evolution
Topic 6: Evolution Topic 6: Evolution
Topic 6: Evolution
 
Topic Five: Genetics
Topic Five: GeneticsTopic Five: Genetics
Topic Five: Genetics
 
Topic 3: Nucleic Acid
Topic 3: Nucleic AcidTopic 3: Nucleic Acid
Topic 3: Nucleic Acid
 
Topic 2: Biochemistry
Topic 2: Biochemistry Topic 2: Biochemistry
Topic 2: Biochemistry
 
11.3 kidney
11.3 kidney11.3 kidney
11.3 kidney
 
11.2 Movement
11.2 Movement 11.2 Movement
11.2 Movement
 
6.5 neurons and synapses
6.5 neurons and synapses 6.5 neurons and synapses
6.5 neurons and synapses
 
Immune system hl
Immune system hlImmune system hl
Immune system hl
 
Ia headings
Ia headingsIa headings
Ia headings
 
6.2 and 6.4 transport and respiration
6.2 and 6.4  transport and respiration6.2 and 6.4  transport and respiration
6.2 and 6.4 transport and respiration
 
6.1 digestion HL Year One
6.1 digestion HL Year One6.1 digestion HL Year One
6.1 digestion HL Year One
 
Ecology Optional Topic Student Notes
Ecology Optional Topic Student NotesEcology Optional Topic Student Notes
Ecology Optional Topic Student Notes
 
C.6 nitrogen cycle .pptx
C.6 nitrogen cycle .pptxC.6 nitrogen cycle .pptx
C.6 nitrogen cycle .pptx
 

Recently uploaded

Recently uploaded (20)

Towards a code of practice for AI in AT.pptx
Towards a code of practice for AI in AT.pptxTowards a code of practice for AI in AT.pptx
Towards a code of practice for AI in AT.pptx
 
Basic Civil Engineering first year Notes- Chapter 4 Building.pptx
Basic Civil Engineering first year Notes- Chapter 4 Building.pptxBasic Civil Engineering first year Notes- Chapter 4 Building.pptx
Basic Civil Engineering first year Notes- Chapter 4 Building.pptx
 
On_Translating_a_Tamil_Poem_by_A_K_Ramanujan.pptx
On_Translating_a_Tamil_Poem_by_A_K_Ramanujan.pptxOn_Translating_a_Tamil_Poem_by_A_K_Ramanujan.pptx
On_Translating_a_Tamil_Poem_by_A_K_Ramanujan.pptx
 
Holdier Curriculum Vitae (April 2024).pdf
Holdier Curriculum Vitae (April 2024).pdfHoldier Curriculum Vitae (April 2024).pdf
Holdier Curriculum Vitae (April 2024).pdf
 
REMIFENTANIL: An Ultra short acting opioid.pptx
REMIFENTANIL: An Ultra short acting opioid.pptxREMIFENTANIL: An Ultra short acting opioid.pptx
REMIFENTANIL: An Ultra short acting opioid.pptx
 
SOC 101 Demonstration of Learning Presentation
SOC 101 Demonstration of Learning PresentationSOC 101 Demonstration of Learning Presentation
SOC 101 Demonstration of Learning Presentation
 
How to Add New Custom Addons Path in Odoo 17
How to Add New Custom Addons Path in Odoo 17How to Add New Custom Addons Path in Odoo 17
How to Add New Custom Addons Path in Odoo 17
 
Accessible Digital Futures project (20/03/2024)
Accessible Digital Futures project (20/03/2024)Accessible Digital Futures project (20/03/2024)
Accessible Digital Futures project (20/03/2024)
 
Kodo Millet PPT made by Ghanshyam bairwa college of Agriculture kumher bhara...
Kodo Millet  PPT made by Ghanshyam bairwa college of Agriculture kumher bhara...Kodo Millet  PPT made by Ghanshyam bairwa college of Agriculture kumher bhara...
Kodo Millet PPT made by Ghanshyam bairwa college of Agriculture kumher bhara...
 
Understanding Accommodations and Modifications
Understanding  Accommodations and ModificationsUnderstanding  Accommodations and Modifications
Understanding Accommodations and Modifications
 
Python Notes for mca i year students osmania university.docx
Python Notes for mca i year students osmania university.docxPython Notes for mca i year students osmania university.docx
Python Notes for mca i year students osmania university.docx
 
Key note speaker Neum_Admir Softic_ENG.pdf
Key note speaker Neum_Admir Softic_ENG.pdfKey note speaker Neum_Admir Softic_ENG.pdf
Key note speaker Neum_Admir Softic_ENG.pdf
 
Jamworks pilot and AI at Jisc (20/03/2024)
Jamworks pilot and AI at Jisc (20/03/2024)Jamworks pilot and AI at Jisc (20/03/2024)
Jamworks pilot and AI at Jisc (20/03/2024)
 
This PowerPoint helps students to consider the concept of infinity.
This PowerPoint helps students to consider the concept of infinity.This PowerPoint helps students to consider the concept of infinity.
This PowerPoint helps students to consider the concept of infinity.
 
Beyond_Borders_Understanding_Anime_and_Manga_Fandom_A_Comprehensive_Audience_...
Beyond_Borders_Understanding_Anime_and_Manga_Fandom_A_Comprehensive_Audience_...Beyond_Borders_Understanding_Anime_and_Manga_Fandom_A_Comprehensive_Audience_...
Beyond_Borders_Understanding_Anime_and_Manga_Fandom_A_Comprehensive_Audience_...
 
COMMUNICATING NEGATIVE NEWS - APPROACHES .pptx
COMMUNICATING NEGATIVE NEWS - APPROACHES .pptxCOMMUNICATING NEGATIVE NEWS - APPROACHES .pptx
COMMUNICATING NEGATIVE NEWS - APPROACHES .pptx
 
How to setup Pycharm environment for Odoo 17.pptx
How to setup Pycharm environment for Odoo 17.pptxHow to setup Pycharm environment for Odoo 17.pptx
How to setup Pycharm environment for Odoo 17.pptx
 
Google Gemini An AI Revolution in Education.pptx
Google Gemini An AI Revolution in Education.pptxGoogle Gemini An AI Revolution in Education.pptx
Google Gemini An AI Revolution in Education.pptx
 
General Principles of Intellectual Property: Concepts of Intellectual Proper...
General Principles of Intellectual Property: Concepts of Intellectual  Proper...General Principles of Intellectual Property: Concepts of Intellectual  Proper...
General Principles of Intellectual Property: Concepts of Intellectual Proper...
 
Plant propagation: Sexual and Asexual propapagation.pptx
Plant propagation: Sexual and Asexual propapagation.pptxPlant propagation: Sexual and Asexual propapagation.pptx
Plant propagation: Sexual and Asexual propapagation.pptx
 

Forensic Dna Me

  • 1. The Indispensable Forensic Science Tool DNA:
  • 2.
  • 3.
  • 4.
  • 5.
  • 6.
  • 7. Homicide or Rapes: OJ Simpson
  • 8.
  • 10.
  • 11.
  • 12.
  • 13.
  • 14. A T A G C C A A C C A A T A T C G G T T G G T T Replication of a single strand of DNA
  • 15.
  • 16.
  • 17. U A U C G G U U G G U U A T A G C C A A C C A A So, a DNA Sequence of: Would have an mRNA sequence of : Use the following table to determine which of the 20 amino acids would make up this sequence. Each group of three nucleotide bases, an RNA triplet codon, is read in order to determine which amino acid is placed in the sequence. The sequence determines the type of protein that is produced. U A U C G G U U G G U U DNA template Strand RNA Strand of Transcribed DNA
  • 18. U A U C G G U U G G U U
  • 19. U A U C G G U U G G U U mRNA Sequence: Would result in this protein amino acid sequence Tyrosine Arginine Leucine Valine Tyrosine Arginine Leucine Valine
  • 20. U A U C G G U U C G U U a one base change in the mRNA Sequence: Would result in this protein amino acid sequence U A U C G G U U G G U U Tyrosine Arginine Phenylalaine Valine Tyrosine Arginine Phenylalaine Valine
  • 21.
  • 22.
  • 23.
  • 24.
  • 25.
  • 26.
  • 27.  
  • 28.
  • 29.
  • 31.
  • 32.
  • 33.
  • 34.
  • 35.
  • 36.
  • 37.  
  • 38.  
  • 39.  
  • 40.  
  • 41.  
  • 42. How do we get so much variation? Recall inheritance patterns...
  • 43.
  • 45.
  • 46.
  • 47.
  • 48.  
  • 49. Genetic Analyzer: SIZE, COLOR & AMOUNT
  • 50.