2. RESEARCH UPDATES ON DRUGS IN
MUKHADOOSHIKA(ACNE VULGARIS)
Under the guidelines of
Dr. Ashalatha M
Professor and HOD
Dept of Dravyaguna
GAMC
Bangalore- 09
By
Dr. Thriveni D.P.
Final year MD
Dept. of Dravyaguna
GAMC
Bangalore-09
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3. Content
Introduction
Acne treatment modalities and kind of drugs
Ayurvedic perspective
Bioactive compounds in Acne
Researches
Few herbal drugs
Conclusion
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8. Bioactive compounds
Glycoside Antioxidant, Antibiotic, Anti-
(Phenolic,Flavonoids) inflammatory
Tannin(hydrosible) -Antimicrobial, Anti-
inflammatory, Antipruritic effects
Condensed tannin(Isoflavones) -Anti-cellulite , Viscoelastic
properties
Fatty acids (Omega-3& omega-6) optimizes permeability in the skin
Volatile oil -Antibacterial, increases the
permiabillity, healing
Terpenoid -Anti-inflammatory
Sesquiterpene -Antimicrobial
Vitamin A Sebostatic, Anti-inflammatory
Vitamin E Antioxidant
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9. Researches
Rathod Suresh- The study of Shalmali w.s.r.to its efficacy on
Mukhadooshika 2002, Tilaka Ayurveda College Pune.
Agravat H.P - Yuvan Pidaka and role of Lodhradi Lepa
there in (Acne )
Sandeep Sagare - Comparative study on Vachadi Lepa and
Mruttika Lepa in Mukhadooshika with special reference to
Acne Vulgaris.
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10. Lodhra- Symplocos racemosa
Part used ‐ Stembark
Action‐ vranaropana,grahi
Constituents Action
Phenolic glycoside- Anti-inflammatory
symploracemoside
Alkaloid- Antiseptic,
loturine,collutrine Antioxidant
(Ref‐Kerala Ayurveda vaidyam)
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11. Vacha- Acorus calamus
Part used‐ Rhizome
Action‐ lekhana
Constituent Action
Monoterpene Anti‐
Terpineol inflammatory
(Ref;Birla Institute of technology and
science,Pharmacy group)
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12. Yasti – Glycirrhiza glabra
Part used- root
Action- vranaropana,
raktadoshahara
Constituent Action
Gycyrrhizin Anti‐inflammatory
Glabridin Hinders
Liquiritin melanogenesis
(Ref;Birla Institute of technology and science,Pharmacy
group)
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13. Manjista- Rubia cordifolia
Part used- root
Action- varnya,raktaprasadana
Constituents Action
Manjistin Anti-inflammtory
Anthroquinone Antibacterial
Antioxidant
(Ref; Review of Articles on Ayurveda and natural
products )
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14. Shalmali- Bombax ceiba
Part used- spines
Action – grahi,pittasranashana
Constituent Action
Shamimin ‐Antimicrobial
Oxalate ‐Disintegrates
hard tissue
(Ref‐ Himalaya drug company,Bangalore)
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16. Conclusion
Ayurveda also given importance to
cosmetics with therapeutics
There are lot of researches done and carrying out on
Mukhadooshika to find still more effficient one.
Further there is a scope for studying these dravyas in
more detail with respect to pharmacokinetics.
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