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Irio Calasso - Medirio, améliorer le traitement du diabète - e-health 6.6.14
1. Medirio SA, Techno-Pôle 10, 3960 Sierre, Switzerland
Journée E-Health
Technoark a Sierre. June 6, 2014
E calasso@medirio.com M +41 79 820 20 86
Irio Calasso, PhD CEO
2. 95% OF PEOPLE ON INSULIN USE SYRINGES AND PENS
PROS OF PENS
• Cost efficient therapy compared to pumps
• Misuse is limited
CONS OF PENS
• Several handling steps before and after injection
• No discreetness
• Injections are burdensome
• No connectivity
5%
DOCTORS PRESCRIBE PUMPS TO ONLY 5% OF PEOPLE ON INSULIN
Medirio SA. June 6, 2014 Journée E-Health Slide 2.
3. HOW M-HEALTH CAN HELP
IN THE DIABETES SUPPORTIVE CARE PROCESS
Medirio SA. June 6, 2014 Journée E-Health Slide 3.
• Track patient condition and behaviors
• Advices and recommendations
• Therapy regime adherence
• Follow-up scheduling
• Social peer-to-peer support
• ..
4. Medirio SA. June 6, 2014 Journée E-Health Slide 4.
J Med Internet Res 2014;16(4):e104
ANNUAL RELEASE FIGURES FOR DIABETES APPS
5. Medirio SA. June 6, 2014 Journée E-Health Slide 5.
J Med Internet Res 2014;16(4):e104
MOBILE APPLICATIONS FOR DIABETES
6. Medirio SA. June 6, 2014 Journée E-Health Slide 6.
To remove the stress related to each
injection thank to an easy, simple to use
and a supportive instrument.
VISION
7. Medirio SA. June 6, 2014 Journée E-Health Slide 7.
A. Disposable adhesive Patch
B. Handheld device as user interface and
controller / drive unit with connectivity
OUR SOLUTION FOR THE PEN MARKET
By placing the handheld device over the patch, the patch
unlocks and receives energy to pump insulin even through the
clothing.
Aesthetic prototype
8. Medirio SA. June 6, 2014 Journée E-Health Slide 8.
INSULIN DELIVERY
A. The dose is selected on the handheld.
B. To inject, the handheld is placed over the
patch for 5 to 15 seconds.
USABILITY
To inject insulin, patients simply place the handheld over the patch.
PREPARATION The disposable patch is attached to the
body for 3 to 4 days.
9. Medirio SA. June 6, 2014 Journée E-Health
IN THE DISPOSABLE PATCH
• No battery
• No electronics
• No motors
Low COG ( similar to insulin disposable pens ) .
Small and easy to wear.
IN THE HANDHELD
• User interface
• Driver and controller for the patch
• Reminders and log-file
• Blood glucose meter
• Connectivity
ENERGY TRANSFER FROM HANDHELD TO PATCH
THE MAGIC BEHIND OUR TECHNOLOGY
Slide 9.
10. Medirio SA. June 6, 2014 Journée E-Health Slide 10.
COMPETITORS LANDSCAPE
GREAT INJECTION EXPERIENCE AND ENHANCED USABILITY AT PEN COSTS
Therapy cost
1500 Euro/year
(95% of the market)
Reimbursed in most countries
3500 Euro/year
(5% of the market)
Reimbursed mainly for type 1
OUR SYSTEM
z
11. Medirio SA. June 6, 2014 Journée E-Health Slide 11.
COMPLETE SYSTEM FOR A SIMPLE “PEN” TREATMENT
Handheld with glucose meter
12. Medirio SA. June 6, 2014 Journée E-Health Slide 12.
APPLICATIONS DATA
EXCHANGE
WIRELESS-ENABLED HANDHELD
Connectivity is one of the services
insulin pens cannot offer. Such service
allows for data recording and sharing
with doctors and relatives. This
provides a powerful tool to improve
treatment compliance.
13. Medirio SA. June 6, 2014 Journée E-Health Slide 13.
APPLICATIONS DATA
EXCHANGE
USB- AND/OR BLUETOOTH-ENABLED
HANDHELD
While a wireless-enabled handheld
would synchronise directly with the
server, a USB/Bluetooth-enabled device
connects to both mobile devices and
personal computers which, in turn, will
synchronise gathered data to and from
the server.
14. Based on the exchange of
+ INSULIN DOSES
+ GLUCOSE LEVELS
Future plans to include the process third parties data as:
+ FITNESS MAPPING
+ WEIGHT LOSS
+ HB1AC LEVELS
+ CARBOHYDRATE CONTENT OF FOOD
Medirio SA. June 6, 2014 Journée E-Health Slide 14.
INFORMED DECISIONS
COMPREHENSIVELY INFORMED THERAPY DECISIONS
15. E-health
– Improve therapy
– Enabling disease
management system
– Reaching communities
– Teaching communities
– Enriching communities
Journée E-Health Slide 15Medirio SA. June 6, 2014
16. Medirio SA, Techno-Pôle 10, 3960 Sierre, Switzerland
or visit us at www.medirio.com
Irio Calasso, PhD CEO E calasso@medirio.com M +41 79 820 20 86
18. Medirio SA. June 6, 2014 Journée E-Health Slide 18. Confidential
PATIENTS ACCEPTANCE
GREAT ACCEPTANCE BY
• People that start with the insulin therapy
• Management of gestational diabetes (3-10% of pregnancies)
• Children with diabetes (parents decide for the children)
Very attractive also for established pen users (see slide “ADVANTAGES”)
OR
19. Medirio SA. June 6, 2014 Journée E-Health Slide 19. Confidential
ENHANCED INJECTION EXPERIENCE Easy, discreet and relaxed
FAST TRAINING AND LEARNING Same therapy regime as for insulin pens
REDUCED PRICKING Pricking amount and fear of injections are greatly reduced
IDEAL PRODUCT for children, gestational diabetes and patients requiring multiple injections
THERAPY TRACKING Log-files are produced to prove and improve therapy outcome
CONNECTIVITY Passing data on to other devices broadens data-related services
ADVANTAGES
20. Medirio SA. June 6, 2014 Journée E-Health Slide 20. Confidential
FAQ
TOPIC ANSWER NOTES
Is the system safe and secure? Yes
Doses, needle occlusion and empty reservoir
are controlled and verified by the handheld device.
Skin irritation due to the patch. Rarely
Other products show low risk for irritation.
The patch is attached to the body likewise as a pump
infusion set.
Waterproof patch device. Yes
Showering and swimming allowed.
( a feature that has been demonstrated with similar products
e.g. “Omnipod path pump” )
Does the needle hurts? Not at all
The needle is a soft cannula as commonly used by
pumps infusion set.
Easily attached to body. Yes
Few easy steps required.
The patch is attached with an double-layer adhesive film.
Insulin in the patch. TBD
A. Patch device is prefilled with insulin;
B. The patch is filled with insulin by the user just before
usage ( as pump users do ).
21. Medirio SA. June 6, 2014 Journée E-Health Slide 21. Confidential
MARKET
INSTRUMENTS USED TO INJECT INSULIN
3.3
1
4.7 9.5
0.9
2
0
2
4
6
8
10
12
14
2008 2015
Users(millions)
Syringe users Pen users Pump users
OUR TARGET
MARKET
Market potential (in W-UE and USA only). 850 million disposable units/year
( Type 1 and Type 2 diabetes on insulin MDI )
22. CURRENT SITUATION
Medirio SA. June 6, 2014 Journée E-Health Slide 22. Confidential
Connectivity available no connectivity connectivity available
100 % use
Lancing devices – Glucose meters
95% use
Insulin pens & syringes
People with diabetes (PWD) PWD on insulin
5% use
insulin pumps