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SURGEON-PERFORMED
          ULTRASOUND IN
     PROCTOLOGICAL PRACTICE

A.P. ZBAR MD MBBS FRCS (Ed) FRCS (Gen) FRACS
       Universities of New England and Newcastle
          Tamworth Rural Referral Centre
                  Tamworth NSW




                   Provincial Surgeons Meeting Wagga Wagga 2008




                                                                  1
ENDOLUMINAL ULTRASONOGRAPHY

First introduced by Law and Bartram in 1989
Association with normal anatomy
Constitutive variations with age
Modifications – 3-dimensional, Contrast enhancement
and Transperineal technology

                   UTILIZATION

                Perirectal Sepsis
                Faecal Incontinence
                Rectal and Anal Cancers
                Functional Disorders




                                                      2
PRINCIPLES OF ULTRASOUND




                           Resolution depends on frequency (MHz)
                           and pulse repetition frequency

                           Lateral resolution is controlled by beam width

                           A standard BK 10 MHz transducer has an
                           axial resolution < 0.05 mm with a lateral
                           resolution of 0.5-1 mm and a focal range
                           of 5-45 mm.




                                                                            3
TECHNIQUES - ENDOANAL




                        LM




         IAS




         EAS




                             4
TECHNIQUES - ENDORECTAL




3-DIMENSIONAL ENDOANAL    TRANSPERINEAL




                                          5
PERIRECTAL SEPSIS

Primary information




                                  6
7
TRANSPERINEAL SONOGRAPHY




                                                Sensitivity for detection of trans-
                                                sphincteric and extrasphincteric
                                                fistulae = 100%

                                                Sensitivity for internal opening
                                                with TPUS is 90% and 80% for
                                                EAUS

                                                Sensitivity for horseshoeing with
                                                TPUS is 28.6%

                                                Sensitivity for ancillary abscess
                                                and secondary tracks with TPUS
Zbar AP et al. Techniques in Coloproctol 2007
                                                is 63.6%




                                                                                      8
FAECAL INCONTINENCE




PREOPERATIVE ENDOANAL   PREOPERATIVE TRANSPERINEAL




                                                     9
Intraoperative
                           Endoanal




Postoperative Endoanal



                           Postoperative
                           Transperineal




                                           10
RECTAL AND ANAL TUMOURS




                          11
NORMAL ENDOSONOGRAPHIC RECTAL WALL LAYERS




                                            12
T1




         SM




                              PF




INFILTRATIVE VILLOUS LESION
NOT INVADING SUBMUCOSA (SM)




                                   13
T2 TUMOUR   T3 TUMOUR




                        14
T4 TUMOUR – SEMINAL VESICLE INFILTRATION

                       Accuracy for T stage   = 85%

                       Accuracy for N staging = 50%

                       SENSITIVITY             75%
                       PPV                     82%




                                                      15
PARARECTAL NODES




Inherent endosonographic problems with nodal detection




                                                         16
WORLDWIDE FIGURES OF ERUS - T AND N STATUS OF RECTAL CANCERS


AUTHOR        YEAR    NR    T ACC   OVERSTAGE   UNDERSTAGE   N ACC
                              (%)                             (%)

HILDEBRANDT   1985    25     92
BEYNON        1987    100    93
RIFKIN        1987    102    67        50
GLASER        1990   117     90                                80
KATSURA       1992   120     92       8.3           5.3        72.3
HERZOG        1993   152     89       10.2          0.8        80.2
FEDAYEV       1995   132     91        3.7          3.7        54.5
ZRIHEN        1996    62     84                                71
GENNA         2000    42     81                                71.4
GARCIA-       2002   545     69        18           13         64
AGUILAR
NESBAKKEN     2003     91    74                                65
HSIEH         2003     67    88             9        3         73
MACKAY        2003    356    89                                66
BALI          2004     33    79         10          10         59


PRESENT       2005     40    85         5           10         50
SERIES




                                                                      17
TRANSPERINEAL SONOGRAPHY IN
RECURRENT ANORECTAL TUMOUR




                              18
Managing Evacuatory Disorders




                                19
DYNAMIC TRANSPERINEAL IMAGING




                                     AXIAL




                                           IAS



                                SAGITTAL




                                                 20
Rectocele             Rectoanal intussusception
 RECTOCELE        RECTOANAL INTUSSUSCEPTION




PERITONEOCELE
  Peritoneocele        ENTEROCELE
                            Enterocele




                                                   21
DYNAMIC TRANSPERINEAL ULTRASONOGRAPHY
    AND THE ANTERIOR COMPARTMENT




                                        22
DYNAMIC TRANSPERINEAL SONOGRAPHY
        IN FUNCTIONAL DISORDERS
RECTOCELE                   CYSTOCELE




                                        23
Beer-Gabel M, Zbar AP DCR 2002

     Zbar AP et al. Dis Colon Rectum 2004




                                            24
DTP-US VERSUS DEFAECOGRAPHY IN EVACUATORY DYSFUNCTION

      PATHOLOGY                 DTP-US                DEFAECOGRAPHY

      One                       6 (18.2%)             12 (36.4%)

      Two                       19 (57.6%)            15 (45.4%)

      Three                     6 (18.2%)             3 (9.1%)

      None                      2 (6%)                3 (9.1%)

                                                                 P = 0.3
     RECTOCELE                 8/17 (47.1%)         4/18 (22.2%)
     PLUS Enterocele
                                                                  P = 0.15
     RECTOCELE
     Sensitivity       88.9%
     Specificity       100%

     RECTOANAL INTUSSUSCEPTION
     Sensitivity 89.5%
     Specificity 100%
                                         Beer-Gabel M, Zbar A et al. Int J Colorect Dis 2005




                                                                                               25
BLAND-ALTMAN PLOT OF ARA AT REST

                                   70

                                   60

                                   50

                                   40

                                   30
                                                                                                  °° °
(Proctography-Ultrasound)Degrees
Difference in Ano-Rectal Angle




                                   20
                                                                 °         °                           °
                                                                                            ° °                      °
                                   10                                                   °              °             °
                                    0                                  °            °                °
                                                                                    °                  °                 °
                                   -10
                                                             °
                                                                                °°°                   °°
                                   -20                                              °
                                                                                    °              ° °
                                   -30                                                            ° °
                                   -40
                                                                                                           °
                                   -50

                                   -60                                              °
                                   -70             °


                                         50   60        70        80           90           100     110        120       130

                                                         Average Change in Ano-Rectal Angle measured by Proctography and Ultrasound (Degrees)




                                                                                                                                                26
BLAND-ALTMAN PLOT OF ARJ DURING STRAINING

                                                 70

                                                 60                                                     °
                                                 50

                                                                                             °               °
Difference in Ano-Rectal Junction Displacement




                                                 40
                                                                                                            °
                                                 30                                                                       °                 °
                                                 20                                                  °°
(Proctography-Ultrasound)Degrees




                                                                                          °
                                                 10                                      °                          °
                                                            ° °                                       °
                                                  0
                                                                             °        ° °°        ° ° °                           °°
                                                 -10                                °                 °            °
                                                                                        °
                                                 -20                                       °       °
                                                 -30         °               °            °
                                                 -40
                                                                                                     °
                                                 -50

                                                 -60

                                                 -70




                                                       70    80   90        100        110        120        130         140        150         160

                                                                   Average Change in Ano-Rectal junction displacement measured by Proctography and Ultrasound (Degrees)




                                                                                                                                                                          27
DYNAMIC TRANSPERINEAL ULTRASONOGRAPHY (DTP-US)

      Simple
      Non-invasive
      Avoids radiation in young patients
      Repeatable
      Portable
      Simultaneously assesses the anterior and posterior perineum & pelvic floor
      Avoids the need for multiorgan opacification

Dynamic transperineal ultrasound is accurate in
the diagnosis of specific pelvic floor conditions

It tends to diagnose multiple conditions in
functional disorders

Quantitative assessment of the pelvic floor is
comparable with defaecography for pelvic
floor disorders at rest and during straining




                                                                                   28

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Surgeon Performed Ultrasound In Proctological Practice

  • 1. SURGEON-PERFORMED ULTRASOUND IN PROCTOLOGICAL PRACTICE A.P. ZBAR MD MBBS FRCS (Ed) FRCS (Gen) FRACS Universities of New England and Newcastle Tamworth Rural Referral Centre Tamworth NSW Provincial Surgeons Meeting Wagga Wagga 2008 1
  • 2. ENDOLUMINAL ULTRASONOGRAPHY First introduced by Law and Bartram in 1989 Association with normal anatomy Constitutive variations with age Modifications – 3-dimensional, Contrast enhancement and Transperineal technology UTILIZATION Perirectal Sepsis Faecal Incontinence Rectal and Anal Cancers Functional Disorders 2
  • 3. PRINCIPLES OF ULTRASOUND Resolution depends on frequency (MHz) and pulse repetition frequency Lateral resolution is controlled by beam width A standard BK 10 MHz transducer has an axial resolution < 0.05 mm with a lateral resolution of 0.5-1 mm and a focal range of 5-45 mm. 3
  • 4. TECHNIQUES - ENDOANAL LM IAS EAS 4
  • 5. TECHNIQUES - ENDORECTAL 3-DIMENSIONAL ENDOANAL TRANSPERINEAL 5
  • 7. 7
  • 8. TRANSPERINEAL SONOGRAPHY Sensitivity for detection of trans- sphincteric and extrasphincteric fistulae = 100% Sensitivity for internal opening with TPUS is 90% and 80% for EAUS Sensitivity for horseshoeing with TPUS is 28.6% Sensitivity for ancillary abscess and secondary tracks with TPUS Zbar AP et al. Techniques in Coloproctol 2007 is 63.6% 8
  • 9. FAECAL INCONTINENCE PREOPERATIVE ENDOANAL PREOPERATIVE TRANSPERINEAL 9
  • 10. Intraoperative Endoanal Postoperative Endoanal Postoperative Transperineal 10
  • 11. RECTAL AND ANAL TUMOURS 11
  • 13. T1 SM PF INFILTRATIVE VILLOUS LESION NOT INVADING SUBMUCOSA (SM) 13
  • 14. T2 TUMOUR T3 TUMOUR 14
  • 15. T4 TUMOUR – SEMINAL VESICLE INFILTRATION Accuracy for T stage = 85% Accuracy for N staging = 50% SENSITIVITY 75% PPV 82% 15
  • 16. PARARECTAL NODES Inherent endosonographic problems with nodal detection 16
  • 17. WORLDWIDE FIGURES OF ERUS - T AND N STATUS OF RECTAL CANCERS AUTHOR YEAR NR T ACC OVERSTAGE UNDERSTAGE N ACC (%) (%) HILDEBRANDT 1985 25 92 BEYNON 1987 100 93 RIFKIN 1987 102 67 50 GLASER 1990 117 90 80 KATSURA 1992 120 92 8.3 5.3 72.3 HERZOG 1993 152 89 10.2 0.8 80.2 FEDAYEV 1995 132 91 3.7 3.7 54.5 ZRIHEN 1996 62 84 71 GENNA 2000 42 81 71.4 GARCIA- 2002 545 69 18 13 64 AGUILAR NESBAKKEN 2003 91 74 65 HSIEH 2003 67 88 9 3 73 MACKAY 2003 356 89 66 BALI 2004 33 79 10 10 59 PRESENT 2005 40 85 5 10 50 SERIES 17
  • 20. DYNAMIC TRANSPERINEAL IMAGING AXIAL IAS SAGITTAL 20
  • 21. Rectocele Rectoanal intussusception RECTOCELE RECTOANAL INTUSSUSCEPTION PERITONEOCELE Peritoneocele ENTEROCELE Enterocele 21
  • 22. DYNAMIC TRANSPERINEAL ULTRASONOGRAPHY AND THE ANTERIOR COMPARTMENT 22
  • 23. DYNAMIC TRANSPERINEAL SONOGRAPHY IN FUNCTIONAL DISORDERS RECTOCELE CYSTOCELE 23
  • 24. Beer-Gabel M, Zbar AP DCR 2002 Zbar AP et al. Dis Colon Rectum 2004 24
  • 25. DTP-US VERSUS DEFAECOGRAPHY IN EVACUATORY DYSFUNCTION PATHOLOGY DTP-US DEFAECOGRAPHY One 6 (18.2%) 12 (36.4%) Two 19 (57.6%) 15 (45.4%) Three 6 (18.2%) 3 (9.1%) None 2 (6%) 3 (9.1%) P = 0.3 RECTOCELE 8/17 (47.1%) 4/18 (22.2%) PLUS Enterocele P = 0.15 RECTOCELE Sensitivity 88.9% Specificity 100% RECTOANAL INTUSSUSCEPTION Sensitivity 89.5% Specificity 100% Beer-Gabel M, Zbar A et al. Int J Colorect Dis 2005 25
  • 26. BLAND-ALTMAN PLOT OF ARA AT REST 70 60 50 40 30 °° ° (Proctography-Ultrasound)Degrees Difference in Ano-Rectal Angle 20 ° ° ° ° ° ° 10 ° ° ° 0 ° ° ° ° ° ° -10 ° °°° °° -20 ° ° ° ° -30 ° ° -40 ° -50 -60 ° -70 ° 50 60 70 80 90 100 110 120 130 Average Change in Ano-Rectal Angle measured by Proctography and Ultrasound (Degrees) 26
  • 27. BLAND-ALTMAN PLOT OF ARJ DURING STRAINING 70 60 ° 50 ° ° Difference in Ano-Rectal Junction Displacement 40 ° 30 ° ° 20 °° (Proctography-Ultrasound)Degrees ° 10 ° ° ° ° ° 0 ° ° °° ° ° ° °° -10 ° ° ° ° -20 ° ° -30 ° ° ° -40 ° -50 -60 -70 70 80 90 100 110 120 130 140 150 160 Average Change in Ano-Rectal junction displacement measured by Proctography and Ultrasound (Degrees) 27
  • 28. DYNAMIC TRANSPERINEAL ULTRASONOGRAPHY (DTP-US) Simple Non-invasive Avoids radiation in young patients Repeatable Portable Simultaneously assesses the anterior and posterior perineum & pelvic floor Avoids the need for multiorgan opacification Dynamic transperineal ultrasound is accurate in the diagnosis of specific pelvic floor conditions It tends to diagnose multiple conditions in functional disorders Quantitative assessment of the pelvic floor is comparable with defaecography for pelvic floor disorders at rest and during straining 28