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Umm Al-Qura University Faculty of Dentistry Dr. Reham Al-Haratani
Demographic Data ,[object Object],[object Object],[object Object],Chief Complaint: Wants to treat her carious teeth.
[object Object],[object Object],[object Object],[object Object],[object Object],History
Extra-oral Examination:
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Clinical Examination ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
INTRA-ORAL EXAMINATION
d. Radiographic Findings
Description of lesion
 
 
So…regarding the   buccal mucosa   (lesion): -Location: Irregularly distributed, bilaterally. -Texture: Smooth.. Does not disappear upon rubbing nor stretching. -Color & Shape: Brown pigmentations + white striations (characteristic Wickham’s striae).
-Size:  Brown pigm.   All over. White striations   extend from retromolar area up to the commissures.  - Lingual gingiva of lower anterior teeth. -Painless - No discomfort upon eating nor swallowing.
[object Object],[object Object],[object Object],Differential diagnosis
[object Object],[object Object],FINAL DIAGNOSIS مرض الحزاز المنبسط   الفموي
[object Object],[object Object],[object Object],[object Object],Investigations done:
 
Last follow-up was on Sunday 8 - 4 - 2007 Showing stability without any progression Follow Up
Treatment Plan… Further follow up every 6 months - 1 year
Background: Autoimmune chronic mucocutaneuos condition. Age:   middle-aged persons Gender:   female predilection   Etiology: T-cell-mediated autoimmune disease. Clinically: Types   Reticular  ASYMPTOMATIC Erosive (ulcerations)  Atrophic (erythema) Bullous (blisters) SYMPTOMATIC – Pre-malignant About Lichen Planus
 
 
OLP associated with patchy brown melanin deposits   28  %   have coincident skin lesions..polygonal papules with white lines on surface
HISTOLOGY: 1. Hyperkeratosis. 2. Acanthosis. 3. Saw-tooth Rete Ridges (shortened). 4. Basal cell degeneration (liquefaction). 5. Band-like lymphocitic infiltration.
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Oral Lichen Planus and Hepatitis C and B viruses :  is there a real association?
[object Object],[object Object],[object Object],[object Object],[object Object]
Methods Results ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],2. Biopsies obtained Confirmed the clinical diagnosis  3. Liver function tests Insignificantly associated 4. Statistical analysis,  assess reliability of liver enz. to predict OLP Not predictive
 
Methods Results ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],2. Biopsies obtained Confirmed the clinical diagnosis  3. Liver function tests Insignificantly associated 4. Statistical analysis,  assess reliability of liver enz. to predict OLP Not predictive
 
Methods Results ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],2. Biopsies obtained Confirmed the clinical diagnosis  3. Liver function tests Insignificantly associated 4. Statistical analysis,  assess reliability of liver enz. to predict OLP Not predictive
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Main conclusion: ,[object Object],[object Object],[object Object]
 
 
References : ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

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Oral Lichen Planus

  • 1. Umm Al-Qura University Faculty of Dentistry Dr. Reham Al-Haratani
  • 2.
  • 3.
  • 5.
  • 6.
  • 10.  
  • 11.  
  • 12. So…regarding the buccal mucosa (lesion): -Location: Irregularly distributed, bilaterally. -Texture: Smooth.. Does not disappear upon rubbing nor stretching. -Color & Shape: Brown pigmentations + white striations (characteristic Wickham’s striae).
  • 13. -Size: Brown pigm. All over. White striations extend from retromolar area up to the commissures. - Lingual gingiva of lower anterior teeth. -Painless - No discomfort upon eating nor swallowing.
  • 14.
  • 15.
  • 16.
  • 17.  
  • 18. Last follow-up was on Sunday 8 - 4 - 2007 Showing stability without any progression Follow Up
  • 19. Treatment Plan… Further follow up every 6 months - 1 year
  • 20. Background: Autoimmune chronic mucocutaneuos condition. Age: middle-aged persons Gender: female predilection Etiology: T-cell-mediated autoimmune disease. Clinically: Types Reticular ASYMPTOMATIC Erosive (ulcerations) Atrophic (erythema) Bullous (blisters) SYMPTOMATIC – Pre-malignant About Lichen Planus
  • 21.  
  • 22.  
  • 23. OLP associated with patchy brown melanin deposits 28 % have coincident skin lesions..polygonal papules with white lines on surface
  • 24. HISTOLOGY: 1. Hyperkeratosis. 2. Acanthosis. 3. Saw-tooth Rete Ridges (shortened). 4. Basal cell degeneration (liquefaction). 5. Band-like lymphocitic infiltration.
  • 25.
  • 26. Oral Lichen Planus and Hepatitis C and B viruses : is there a real association?
  • 27.
  • 28.
  • 29.  
  • 30.
  • 31.  
  • 32.
  • 33.
  • 34.
  • 35.  
  • 36.  
  • 37.