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Chapter
Viruses
 Ch 19
Viruses
Characteristics of Viruses
    1. Tiny, nonliving particles
          a. do not respire, move, grow
    2. Must reproduce inside of a host
    3. Pathogens: disease-causing
         a. Virulence: degree of response
         caused in a host
    4. Not given latin names
         a. named for disease caused,
         organ infected, or region first
         detected in
Viral Structure
1. Inner core of nucleic acid surrounded
   by protein coat called capsid
     a. head contains either DNA or RNA




  body
Figure 19-13 Virus Structures

           Section 19-3




                                            Tobacco Mosaic
              T4 Bacteriophage                   Virus
                                                                                   Influenza
                                  DNA                         RNA                    Virus
     Head
                                                                                               RNA
                                                             Capsid     Capsid
                                                             proteins


     Tail
     sheath
                                    Tail
                                    fiber



                                                                        Surface
                                                                        proteins           Membrane
                                                                                           envelope




Go to
Section:
Recognition & Attachment of Viruses
1. Virus must recognize specific
receptor site on host.
      A. part of the virus matches site
      on host
      B. lands on host and “locks in”
2. Attachment is specific
     a. virus can enter & reproduce in
     only a few kinds of cells
Example: tobacco mosaic virus cannot
affect human cells even though we are
exposed to it.
There are 2 ways viruses can reproduce
   inside a host.
1. Lytic cycle-fast
2. Lysogenic cycle-slow
Lysogenic Cycle( virus can enter a period
of inactivity before becoming lytic)
STEPS
1. Attachment- virus attaches to the host
cell
2. Entry- whole virus or just nucleic acid
enters the cell
3. Replication- viral nucleic acid joins
w/DNA of host cell. It may stay there
inactive for years. Host cell continues to
divide
If the cell reproduces, the viral nucleic acid is also
copied so each new cell is infected.
4. the virus becomes active and enters the lytic cycle.
5. Assembly,lysis, & release- new viral nucleic acids &
protein coats are assembled. The virus exits the host
cell.
Example- AIDS, Herpes
Figure 19-15 A Lysogenic Infection

           Section 19-3


                            Bacteriophage                         Bacterial
                                     DNA                          chromosome




                                          Bacteriophage injects                         Bacteriophage DNA
                                          DNA into bacterium                            (prophage) can exit the
                                                                                        bacterial chromosome




                                                  Lytic                                     Lysogenic
                                                  Cycle                                     Cycle
             Bacteriophage enzyme lyses the                         Bacteriophage DNA                      Bacteriophage DNA
                                                                    forms a circle                         (prophage) may replicate
             bacterium’s cell wall, releasing
                                                                                                           with bacterium for many
             new bacteriophage particles that
                                                                                                           generations
             can attack other cells                                                       Prophage




                                       Bacteriophage proteins and                       Bacteriophage DNA
                                       nucleic acids assemble into                      inserts itself into
                                       complete bacteriophage particles                 bacterial chromosome




Go to
Section:
Common Diseases Caused by Viruses

           Section 19-3




                Type of Virus       Nucleic Acid   Disease
                Oncogenic viruses   DNA            cancer
                Retroviruses        RNA            cancer, AIDS
                Adenoviruses        DNA            respiratory infections
                Herpesviruses       DNA            chickenpox
                Poxviruses          DNA            smallpox




Go to
Section:
Go to
Section:

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Viruses2011

  • 2. Characteristics of Viruses 1. Tiny, nonliving particles a. do not respire, move, grow 2. Must reproduce inside of a host 3. Pathogens: disease-causing a. Virulence: degree of response caused in a host 4. Not given latin names a. named for disease caused, organ infected, or region first detected in
  • 3. Viral Structure 1. Inner core of nucleic acid surrounded by protein coat called capsid a. head contains either DNA or RNA body
  • 4. Figure 19-13 Virus Structures Section 19-3 Tobacco Mosaic T4 Bacteriophage Virus Influenza DNA RNA Virus Head RNA Capsid Capsid proteins Tail sheath Tail fiber Surface proteins Membrane envelope Go to Section:
  • 5. Recognition & Attachment of Viruses 1. Virus must recognize specific receptor site on host. A. part of the virus matches site on host B. lands on host and “locks in”
  • 6. 2. Attachment is specific a. virus can enter & reproduce in only a few kinds of cells Example: tobacco mosaic virus cannot affect human cells even though we are exposed to it.
  • 7. There are 2 ways viruses can reproduce inside a host. 1. Lytic cycle-fast 2. Lysogenic cycle-slow
  • 8. Lysogenic Cycle( virus can enter a period of inactivity before becoming lytic) STEPS 1. Attachment- virus attaches to the host cell 2. Entry- whole virus or just nucleic acid enters the cell 3. Replication- viral nucleic acid joins w/DNA of host cell. It may stay there inactive for years. Host cell continues to divide
  • 9. If the cell reproduces, the viral nucleic acid is also copied so each new cell is infected. 4. the virus becomes active and enters the lytic cycle. 5. Assembly,lysis, & release- new viral nucleic acids & protein coats are assembled. The virus exits the host cell. Example- AIDS, Herpes
  • 10. Figure 19-15 A Lysogenic Infection Section 19-3 Bacteriophage Bacterial DNA chromosome Bacteriophage injects Bacteriophage DNA DNA into bacterium (prophage) can exit the bacterial chromosome Lytic Lysogenic Cycle Cycle Bacteriophage enzyme lyses the Bacteriophage DNA Bacteriophage DNA forms a circle (prophage) may replicate bacterium’s cell wall, releasing with bacterium for many new bacteriophage particles that generations can attack other cells Prophage Bacteriophage proteins and Bacteriophage DNA nucleic acids assemble into inserts itself into complete bacteriophage particles bacterial chromosome Go to Section:
  • 11. Common Diseases Caused by Viruses Section 19-3 Type of Virus Nucleic Acid Disease Oncogenic viruses DNA cancer Retroviruses RNA cancer, AIDS Adenoviruses DNA respiratory infections Herpesviruses DNA chickenpox Poxviruses DNA smallpox Go to Section: