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Hair Bang & Hair Boom
Low Level Laser Therapy (LLLT)
Clinical Research Studies
Total Hair Loss Solution
Hair Bang & Hair Boom
Low Level Laser Therapy (LLLT)
Clinical Research Studies
Total Hair Loss Solution 2
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<Contents>
1. Summary (p.3)
2. Research 1 - Low-level light therapy for androgenetic alopecia: a 24-week, randomized,
double-blind, sham device-controlled multicenter trial. (Hair Boom & Hair
Bang Clinical Research-Performed by WONTECH and Bundang Seoul
National University & Kyungbuk University Hospital) (p.4)
3. Research 2 - Efficacy and Safety of a Low-level Laser Device in the Treatment of Male
and Female Pattern Hair Loss: A Multicenter, Randomized, Sham Device-
controlled, Double-blind Study. (p.12)
4. Research 3 - The Growth of Human Scalp Hair in Females Using Visible Red Light
Laser and LED Sources (p.26)
5. Research 4 - Low-Level Laser (Light) Therapy (LLLT) for Treatment of Hair Loss (p.35)
6. Research 5 - Low-level laser (Light) therapy (LLLT) in skin: stimulating, healing, restoring
(p.44)
7. Hair Bang Trial - Hair Bang test in Korean clinics:
Bun-dang Go-Woon Clinic, Seoul Miracle Clinic, Seoul Moram Clinic,
Seoul Tatoa Clinic (Hair Boom & Hair Bang Test) (p.57)
Appendix
Hair Bang & Hair Boom
Low Level Laser Therapy (LLLT)
Clinical Research Studies
Total Hair Loss Solution 3
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<Research Summury>
Title Objective Result
Research 1
Low-level light the
rapy for androgen
etic alopecia: a 24
-week, randomize
d, double-blind, s
ham device-contr
olled multicenter t
rial.
To evaluate the
efficacy and saf
ety of LLLT (Hai
r Bang & Hair B
oom
After 24 weeks of treatment, the LLLT group showed significantl
y greater hair density than the sham device group. Mean hair di
ameter improved statistically significantly more in the LLLT grou
p than in the sham device group No serious adverse reactions
were detected.
Research 2
Efficacy and Safety
of a Low-level Las
er Device in the Tr
eatment of Male a
nd Female Pattern
Hair Loss: A Multic
enter, Randomized
, Sham Device-con
trolled, Double-bli
nd Study
To determine w
hether treatme
nt with a low le
vel laser device
increases termi
nal hair density
in both men an
d women with
pattern hair los
s.
Seventy-eight, 63, 49, and 79 subjects were randomized in four
trials of 9-beam lasercomb treatment in female subjects, 12-bea
m lasercomb treatment in female subjects, 7-beam lasercomb tr
eatment in male subjects, and 9- and 12-beam lasercomb treat
ment in male subjects. Higher percentage of laser-treated subje
cts reported overall improvement of hair loss.
Research 3
The Growth of Hu
man Scalp Hair in
Females Using Visi
ble Red Light Lase
r and LED Sources
To define the s
afety and physi
ologic effects o
f LLLT on femal
es with androg
enic alopecia.
Forty-two patients completed the study (24 active, 18 sham). Th
e active group received a “TOPHAT655” unit containing 21, 5 m
W diode lasers (655 5 nm) and 30 LEDS (655 20 nm) Baseline
hair counts were 228.2 133.4 (N ¼ 18) in the sham and 209.6
118.5 (N ¼ 24) in the active group (P ¼ 0.642). The percent hair
increase over the duration of the study was 11.05 48.30 (N ¼ 1
8) for the sham group and 48.07 17.61 (N ¼ 24) for the active
group (P < 0.001). This demonstrates a 37% increase in hair gro
wth in the active treatment group as compared to the placebo
group.
Research 4
Low-Level Laser (L
ight) Therapy (LLL
T) for Treatment o
f Hair Loss
Pinar Avci et al
(Lasers Surg M
ed. 2014)
This review surveys the evidence for low-level laser therapy (LLL
T) applied to the scalp as a treatment for hair loss and discusse
s possible mechanisms of actions.
Research 5
Low-level laser (Li
ght) therapy (LLLT)
in skin: stimulating
, healing, restoring
This review will
cover the use o
f LLLT as possib
ly the ultimate
non-invasive ap
proach to treati
ng the skin.
The application of LLLT to disorders of pigmentation may work
both ways by producing both repigmentation of vitiligo, and de
pigmentation of hyperpigmented lesions depending on the dosi
metric parameters. The introduction of LED array-based devices
has simplified the application to large areas of skin.
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2. Research 1 | P.
Total Hair Loss Solution
2. Research Ⅰ
Lee Seok Jong, Huh Chang Hun et al. Low-level light therapy for androgenetic
alopecia: a 24-week, randomized, double-blind, sham device-controlled multicenter
trial. Dermatol Surg. 2013;1–7
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3. Research 2 | P.
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3. Research Ⅱ
Joaquin J. Jimenez, Tongyu C. Wikramanayake, Wilma Bergfeld, Maria Hordinsky,
Janet G. Hickman, Michael R. Hamblin and Lawrence A. Schachner. Efficacy and
Safety of a Low-level Laser Device in the Treatment of Male and Female Pattern Hair
Loss: A Multicenter, Randomized, Sham Device-controlled, Double-blind Study. Am J
Clin Dermatol. (2014) 15:115–127
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4. Research Ⅲ
Raymond J. Lanzafame, Raymond R. Blanche, Richard P. Chiacchierini, Eric R.
Kazmirek, and Jeffrey A. Sklar. The Growth of Human Scalp Hair in Females Using
Visible Red Light Laser and LED Sources. Lasers in Surgery and Medicine 46:601–
607 (2014)
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5. Research Ⅳ
Pinar Avci, Gaurav K. Gupta, Jason Clark, Norbert Wikonkal, and Michael R. Hamblin.
Low-Level Laser (Light) Therapy (LLLT) for Treatment of Hair Loss. Lasers Surg Med.
2014 February ; 46(2): 144–151
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6. Research Ⅴ
Pinar Avci, Asheesh Gupta, Magesh Sadasivam, Daniela Vecchio, Zeev Pam, Nadav
Pam, and Michael R Hamblin. Low-level laser (Light) therapy (LLLT) in skin:
stimulating, healing, restoring. Semin Cutan Med Surg. 2013 March ; 32(1): 41–52.
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7. Hair Bang Trial
Hair Boom & Hair Bang test in three Korean clinics: Bun-dang Go-Woon Clinic, Seoul
Miracle Clinic, Seoul Moram Clinic. (Hair Boom & Hair Bang Test)
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7. Hair Bang Trial
Background
Background Nowadays, more and more people suffer from the hair loss and they desire to get
their hair back. Hairbang is a non- invasive low level laser system for hair regrowth and hair
regeneration. This is equipped with highly effective 27LDs and 42LEDs modules to maximize
the treatment result. Androgenetic alopecia (AGA) is a common disorder affecting men and
women. Finasteride and Minoxidil are well-known. Effective treatment methods. Patient who
exhibit a poor response to these methods have no additional adequate treatment modalities
Treatment
Period
2013.05~2013.12
Satisfaction
Assessment
24 weeks after treatment completion
Total Patients201 (AGA, Systemic Disease, Korean 100%)
Gender Ratio Men 75%, Women 25%
Objective
To verify the efficacy and safety of Hair Bang, we recruit 200 participants simultaneously at
three Korean clinics in a same way.
Result
• 198 of 201 (99%) participants responded the result was clinically effective.
• 109 of 201 (54%), 72 of 201 (36%) participants responded their condition had been improved
• 11 participants who volunteered to take a digital photograph recognized that their average 2
2 hair had grown up.
Hair Bang
Laser Type LD/LED
Function(mode) Laser, Vibration
Wavelength 630nm/650nm/660nm
Module LD 27 + LED 42
Treatment Time 18
■ Research Summary
irradiate the whole scalp
widely
 Activates hair follicle
Stimulate and widen capillary
Vessel
 Improves blood flow and
blood circulation
Activate blood flow
 Supplies sufficient nutrition
and delivers Oxygen
■ Product Detail ■ Treatment Principle
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■ Trial Detail
7. Hair Bang Trial
Patient Population
• Patient global assessment was measured on a visual analogue scale (designation 0 indicating no growth or aggra
vation and 10 indicating 100% restoration of AGA at the 1 and 24 weeks visits)
• The investigator assessed the patients using visual inspection and digital photographs at the baseline and 1 week
and 24 weeks visits
• 200 patients with moderate to severe
• Excluded individuals who had used topical or systemic medication affecting hair growth, such as Finasteride, Minox
idil within past 6 months.
• Patients who had hair disorder other than AGA or systemic diseases.
Methods
• Hamilton Classification of Ⅲ to Ⅶ for men or Ludwing classification of Ⅰ to Ⅲ for women.
• The ‘HairBang’ is a helmet type-3R LLLT device with a light source consisting of light-emitting diodes (LEDs) emitti
ng wavelength of 630nm,660nm and laser diodes(LDs) emitting 650nm.
• Diodes run simultaneously through six cycles, each consisting of 2 minutes 50 seconds on and 10 seconds off
• Patients were instructed how to operate each device at the baseline visit and scheduled to use it for 18 minutes on
ce a daily for 24 weeks.
• Follow –up visit were scheduled 1 and 24 weeks after the study began to evaluate subjects
Assessment
• Using a Phototrichogram
• Global Assessment of Hair regrowth according to the patient and investigator.
■ Result
Score Patient Observer
0 3 3
1 11 10
2 22 37
3 23 34
4 24 37
5 42 30
6 33 27
7 24 17
8 15 6
9 4 0
Total 201 201
Patient Observer
Average 4.73 4.04
Patient Score
Patient score average
0
10
20
30
40
50
5 6 7 8 9
Patient Observer
Patient & Observer,
having the score above 5
Patient No. 1w 24w regrowth
106 87 114 27
107 68 91 23
108 57 92 35
109 85 102 17
110 75 101 26
111 57 96 39
112 68 81 13
113 83 101 18
114 83 101 18
115 74 85 11
116 106 121 15
Count
Regrowth Average 22
Hair Growth
1w
0
50
100
150
106 108 110 112 114 116
1w 24w
Patient no.
NumberofHair
Comparison of Hair Growth with Baseline (1w)
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Appendix Trial Patients Profile
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Appendix | P.
Appendix
Nationality Hospital Name Dr.Name
Patient Na
me
Age Sex
Interval (We
eks)
F/U Data Point (S) Point (O) F/U Date Point (S) Point (O)
1 Korea Bundang Gowoon Clinic SooMi, Kim BSY 55 M 1w,24w 2013.04.20 1 1 2013.10.04 9 9
2 Korea Bundang Gowoon Clinic SooMi, Kim KBJ 49 M 1w,24w 2013.05.06 0 2 2013.10.14 8 8
3 Korea Bundang Gowoon Clinic SooMi, Kim CMS 44 M 1w,24w 2013.05.06 0 2 2013.10.14 8 7
4 Korea Bundang Gowoon Clinic SooMi, Kim SHS 31 M 1w,24w 2013.05.08 0 1 2013.10.16 8 7
5 Korea Bundang Gowoon Clinic SooMi, Kim KBJ 36 M 1w,24w 2013.05.08 0 3 2013.10.16 7 7
6 Korea Bundang Gowoon Clinic SooMi, Kim K이 60 M 1w,24w 2013.05.08 4 5 2013.10.16 7 8
7 Korea Bundang Gowoon Clinic SooMi, Kim KUH 46 M 1w,24w 2013.05.13 6 5 2013.10.21 7 8
8 Korea Bundang Gowoon Clinic SooMi, Kim HIH 39 M 1w,24w 2013.05.15 3 2 2013.10.24 6 7
9 Korea Bundang Gowoon Clinic SooMi, Kim YEL 55 M 1w,24w 2013.05.13 1 2 2013.10.21 6 5
10 Korea Bundang Gowoon Clinic SooMi, Kim KJY 29 M 1w,24w 2013.05.05 1 2 2013.10.14 5 6
11 Korea Bundang Gowoon Clinic SooMi, Kim KDB 50 M 1w,24w 2013.05.06 1 0 2013.10.14 7 6
12 Korea Bundang Gowoon Clinic SooMi, Kim KWJ 31 M 1w,24w 2013.05.07 1 1 2013.10.15 7 8
13 Korea Bundang Gowoon Clinic SooMi, Kim KEB 42 M 1w,24w 2013.05.08 0 1 2013.10.18 8 8
14 Korea Bundang Gowoon Clinic SooMi, Kim KEJ 56 M 1w,24w 2013.05.08 2 2 2013.10.18 5 7
15 Korea Bundang Gowoon Clinic SooMi, Kim KHK 62 M 1w,24w 2013.05.10 2 3 2013.10.18 7 6
16 Korea Bundang Gowoon Clinic SooMi, Kim NSR 64 M 1w,24w 2013.05.13 1 2 2013.10.21 8 8
17 Korea Bundang Gowoon Clinic SooMi, Kim NHS 40 M 1w,24w 2013.05.15 1 0 2013.10.23 9 8
18 Korea Bundang Gowoon Clinic SooMi, Kim PSY 59 M 1w,24w 2013.05.15 0 1 2013.10.23 9 9
19 Korea Bundang Gowoon Clinic SooMi, Kim PSJ 41 M 1w,24w 2013.05.10 6 6 2013.10.25 9 8
20 Korea Bundang Gowoon Clinic SooMi, Kim BJO 32 M 1w,24w 2013.05.12 4 3 2013.10.28 9 9
21 Korea Bundang Gowoon Clinic SooMi, Kim SYJ 66 M 1w,24w 2013.05.13 2 3 2013.10.28 10 9
22 Korea Bundang Gowoon Clinic SooMi, Kim SHJ 21 M 1w,24w 2013.05.13 3 3 2013.10.28 8 7
23 Korea Bundang Gowoon Clinic SooMi, Kim YSJ 43 M 1w,24w 2013.05.13 5 4 2013.10.28 9 9
24 Korea Bundang Gowoon Clinic SooMi, Kim OIS 52 M 1w,24w 2013.05.16 4 4 2013.10.30 8 8
25 Korea Bundang Gowoon Clinic SooMi, Kim YHJ 38 M 1w,24w 2013.05.16 2 2 2013.10.30 9 9
26 Korea Bundang Gowoon Clinic SooMi, Kim YJH 39 M 1w,24w 2013.05.17 7 6 2013.10.30 8 9
27 Korea Bundang Gowoon Clinic SooMi, Kim LSM 57 M 1w,24w 2013.05.18 4 5 2013.10.30 7 7
28 Korea Bundang Gowoon Clinic SooMi, Kim LYS 42 M 1w,24w 2013.05.18 3 3 2013.10.30 8 7
29 Korea Bundang Gowoon Clinic SooMi, Kim LWJ 22 M 1w,24w 2013.05.19 6 6 2013.10.30 9 8
30 Korea Bundang Gowoon Clinic SooMi, Kim LYJ 51 M 1w,24w 2013.05.19 1 1 2013.10.31 6 7
31 Korea Bundang Gowoon Clinic SooMi, Kim ISC 21 M 1w,24w 2013.05.20 5 5 2013.10.31 7 7
32 Korea Bundang Gowoon Clinic SooMi, Kim JHL 42 M 1w,24w 2013.05.21 4 4 2013.10.31 9 9
33 Korea Bundang Gowoon Clinic SooMi, Kim JYJ 22 M 1w,24w 2013.05.22 3 3 2013.10.31 8 8
34 Korea Bundang Gowoon Clinic SooMi, Kim JYB 67 F 1w,24w 2013.05.23 4 3 2013.11.02 8 7
35 Korea Bundang Gowoon Clinic SooMi, Kim JEH 47 M 1w,24w 2013.05.24 1 1 2013.11.02 9 7
36 Korea Bundang Gowoon Clinic SooMi, Kim JYJ 51 M 1w,24w 2013.05.25 5 4 2013.11.02 9 8
37 Korea Bundang Gowoon Clinic SooMi, Kim JYJ 61 M 1w,24w 2013.05.06 2 3 2013.11.02 5 5
38 Korea Bundang Gowoon Clinic SooMi, Kim CHJ 59 M 1w,24w 2013.05.06 2 3 2013.11.02 7 6
39 Korea Bundang Gowoon Clinic SooMi, Kim HAS 66 F 1w,24w 2013.05.06 3 3 2013.11.02 7 6
40 Korea Bundang Gowoon Clinic SooMi, Kim HYE 40 M 1w,24w 2013.05.08 3 3 2013.11.05 7 6
41 Korea Bundang Gowoon Clinic SooMi, Kim KEJ 69 M 1w,24w 2013.05.08 1 1 2013.11.05 5 5
42 Korea Bundang Gowoon Clinic SooMi, Kim KDE 53 M 1w,24w 2013.05.08 4 4 2013.11.05 9 9
43 Korea Bundang Gowoon Clinic SooMi, Kim KMH 43 M 1w,24w 2013.05.13 3 3 2013.11.08 8 8
44 Korea Bundang Gowoon Clinic SooMi, Kim KEJ 50 M 1w,24w 2013.05.15 3 3 2013.11.10 7 8
45 Korea Bundang Gowoon Clinic SooMi, Kim KHS 36 M 1w,24w 2013.05.15 4 4 2013.11.10 7 6
46 Korea Bundang Gowoon Clinic SooMi, Kim NMY 51 M 1w,24w 2013.05.24 2 2 2013.12.02 8 7
47 Korea Bundang Gowoon Clinic SooMi, Kim PKM 65 M 1w,24w 2013.05.24 3 4 2013.12.02 9 8
48 Korea Bundang Gowoon Clinic SooMi, Kim PYL 69 F 1w,24w 2013.06.03 3 4 2013.12.12 9 9
49 Korea Bundang Gowoon Clinic SooMi, Kim PJH 48 M 1w,24w 2013.06.03 4 3 2013.12.12 9 9
50 Korea Bundang Gowoon Clinic SooMi, Kim PHJ 32 M 1w,24w 2013.06.04 2 2 2013.12.12 9 9
51 Korea Bundang Gowoon Clinic SooMi, Kim SHJ 50 M 1w,24w 2013.06.04 2 2 2013.12.16 8 8
52 Korea Bundang Gowoon Clinic SooMi, Kim SSB 31 M 1w,24w 2013.06.04 1 1 2013.12.16 7 7
53 Korea Bundang Gowoon Clinic SooMi, Kim UDJ 30 M 1w,24w 2013.06.05 2 3 2013.12.17 7 6
54 Korea Bundang Gowoon Clinic SooMi, Kim USJ 44 M 1w,24w 2013.06.05 4 4 2013.12.17 8 8
55 Korea Bundang Gowoon Clinic SooMi, Kim YNR 67 M 1w,24w 2013.06.10 2 2 2013.12.18 5 5
56 Korea Bundang Gowoon Clinic SooMi, Kim LSM 54 M 1w,24w 2013.06.11 4 4 2013.12.18 6 6
57 Korea Bundang Gowoon Clinic SooMi, Kim LYS 46 M 1w,24w 2013.06.12 1 1 2013.12.18 6 6
58 Korea Bundang Gowoon Clinic SooMi, Kim LJW 48 M 1w,24w 2013.06.13 3 2 2013.12.18 7 7
59 Korea Bundang Gowoon Clinic SooMi, Kim LHR 32 M 1w,24w 2013.06.13 0 0 2013.12.18 5 5
■ Trial Patients Profile – Bundang Gowoon Clinic
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Appendix
■ Trial Patients Profile – Seoul Miracle Clinic
Nationality Hospital Name Dr.Name Patient Name Age Sex Interval (Weeks) F/U Data Point (S) Point (O) F/U Date Point (S) Point (O)
60 Korea Seoul Miracle Clinic Mansik,Cho KDE 51 M 1w,24w 2013.04.20 1 1 2013.10.14 7 8
61 Korea Seoul Miracle Clinic Mansik,Cho KMJ 60 M 1w,24w 2013.04.20 1 1 2013.10.14 8 8
62 Korea Seoul Miracle Clinic Mansik,Cho KAN 66 M 1w,24w 2013.04.20 0 1 2013.10.14 7 7
63 Korea Seoul Miracle Clinic Mansik,Cho KBK 64 M 1w,24w 2013.04.20 0 1 2013.10.11 7 6
64 Korea Seoul Miracle Clinic Mansik,Cho KAJ 55 F 1w,24w 2013.04.23 4 4 2013.10.16 8 8
65 Korea Seoul Miracle Clinic Mansik,Cho NJH 51 M 1w,24w 2013.04.23 0 0 2013.10.16 6 5
66 Korea Seoul Miracle Clinic Mansik,Cho NHR 41 M 1w,24w 2013.04.24 1 1 2013.10.21 7 5
67 Korea Seoul Miracle Clinic Mansik,Cho PSE 65 M 1w,24w 2013.04.24 0 0 2013.10.24 5 5
68 Korea Seoul Miracle Clinic Mansik,Cho PJS 71 M 1w,24w 2013.04.24 0 0 2013.10.21 7 5
69 Korea Seoul Miracle Clinic Mansik,Cho SHS 23 M 1w,24w 2013.04.25 3 3 2013.10.11 9 8
70 Korea Seoul Miracle Clinic Mansik,Cho KEY 63 M 1w,24w 2013.04.25 2 2 2013.10.11 7 6
71 Korea Seoul Miracle Clinic Mansik,Cho SDI 71 M 1w,24w 2013.04.27 1 1 2013.10.11 4 4
72 Korea Seoul Miracle Clinic Mansik,Cho SHS 45 M 1w,24w 2013.04.27 2 2 2013.10.14 6 4
73 Korea Seoul Miracle Clinic Mansik,Cho LMA 35 M 1w,24w 2013.04.27 2 2 2013.10.15 9 8
74 Korea Seoul Miracle Clinic Mansik,Cho LMY 64 F 1w,24w 2013.04.27 2 1 2013.10.14 8 7
75 Korea Seoul Miracle Clinic Mansik,Cho LYJ 40 M 1w,24w 2013.04.30 1 1 2013.10.14 5 3
76 Korea Seoul Miracle Clinic Mansik,Cho GSH 62 M 1w,24w 2013.05.01 3 3 2013.10.17 9 9
77 Korea Seoul Miracle Clinic Mansik,Cho KKY 40 M 1w,24w 2013.05.02 5 5 2013.10.17 8 8
78 Korea Seoul Miracle Clinic Mansik,Cho KGR 49 M 1w,24w 2013.05.02 1 1 2013.10.16 8 8
79 Korea Seoul Miracle Clinic Mansik,Cho KMS 45 M 1w,24w 2013.05.03 4 4 2013.10.16 7 6
80 Korea Seoul Miracle Clinic Mansik,Cho KSH 33 M 1w,24w 2013.05.03 6 6 2013.10.17 9 9
81 Korea Seoul Miracle Clinic Mansik,Cho KYS 61 M 1w,24w 2013.05.03 4 5 2013.10.17 9 7
82 Korea Seoul Miracle Clinic Mansik,Cho KYN 34 M 1w,24w 2013.05.03 4 5 2013.10.18 9 8
83 Korea Seoul Miracle Clinic Mansik,Cho KEY 51 M 1w,24w 2013.05.04 2 2 2013.10.17 9 8
84 Korea Seoul Miracle Clinic Mansik,Cho KJE 40 M 1w,24w 2013.05.04 3 2 2013.10.17 8 9
85 Korea Seoul Miracle Clinic Mansik,Cho SYK 52 M 1w,24w 2013.05.07 1 1 2013.10.22 8 8
86 Korea Seoul Miracle Clinic Mansik,Cho YSM 33 M 1w,24w 2013.05.08 6 6 2013.10.21 9 9
87 Korea Seoul Miracle Clinic Mansik,Cho LJY 49 M 1w,24w 2013.05.08 2 2 2013.10.21 9 9
88 Korea Seoul Miracle Clinic Mansik,Cho LHS 68 M 1w,24w 2013.05.10 1 3 2013.10.21 4 4
89 Korea Seoul Miracle Clinic Mansik,Cho CYJ 50 M 1w,24w 2013.05.22 2 2 2013.10.22 8 8
90 Korea Seoul Miracle Clinic Mansik,Cho HSY 62 M 1w,24w 2013.05.22 0 0 2013.10.24 9 6
91 Korea Seoul Miracle Clinic Mansik,Cho KRK 42 M 1w,24w 2013.05.22 3 3 2013.10.31 8 8
92 Korea Seoul Miracle Clinic Mansik,Cho KYJ 68 M 1w,24w 2013.05.22 2 2 2013.10.31 8 6
93 Korea Seoul Miracle Clinic Mansik,Cho KTK 64 M 1w,24w 2013.05.24 1 1 2013.10.30 6 6
94 Korea Seoul Miracle Clinic Mansik,Cho NSY 61 M 1w,24w 2013.05.24 2 3 2013.10.31 9 7
95 Korea Seoul Miracle Clinic Mansik,Cho LHJ 47 F 1w,24w 2013.05.25 7 5 2013.10.31 8 9
96 Korea Seoul Miracle Clinic Mansik,Cho JYJ 40 F 1w,24w 2013.05.28 5 5 2013.10.31 8 8
97 Korea Seoul Miracle Clinic Mansik,Cho KSH 44 M 1w,24w 2013.05.28 4 4 2013.11.01 9 9
98 Korea Seoul Miracle Clinic Mansik,Cho HCH 46 M 1w,24w 2013.05.28 7 6 2013.11.02 9 9
99 Korea Seoul Miracle Clinic Mansik,Cho KHJ 40 M 1w,24w 2013.05.29 5 5 2013.11.10 8 8
100 Korea Seoul Miracle Clinic Mansik,Cho RHM 52 M 1w,24w 2013.05.29 1 2 2013.11.11 3 4
101 Korea Seoul Miracle Clinic Mansik,Cho WTY 47 F 1w,24w 2013.05.30 2 1 2013.11.05 9 9
102 Korea Seoul Miracle Clinic Mansik,Cho LSH 46 F 1w,24w 2013.05.31 3 3 2013.11.05 9 9
103 Korea Seoul Miracle Clinic Mansik,Cho JHH 31 F 1w,24w 2013.06.01 2 2 2013.11.04 9 9
104 Korea Seoul Miracle Clinic Mansik,Cho PDH 30 F 1w,24w 2013.06.01 1 1 2013.11.04 8 8
105 Korea Seoul Miracle Clinic Mansik,Cho MJH 38 F 1w,24w 2013.06.01 5 5 2013.11.04 7 7
106 Korea Seoul Miracle Clinic Mansik,Cho syj 34 F 1w,24w 2013.06.04 6 6 2013.11.06 7 7
107 Korea Seoul Miracle Clinic Mansik,Cho LJK 31 F 1w,24w 2013.06.04 4 4 2013.11.07 6 5
108 Korea Seoul Miracle Clinic Mansik,Cho JBJ 49 F 1w,24w 2013.06.04 4 4 2013.11.07 6 5
109 Korea Seoul Miracle Clinic Mansik,Cho HSJ 40 F 1w,24w 2013.06.05 1 2 2013.11.07 8 7
110 Korea Seoul Miracle Clinic Mansik,Cho KJO 33 F 1w,24w 2013.06.06 2 2 2013.11.07 8 8
111 Korea Seoul Miracle Clinic Mansik,Cho SYH 30 F 1w,24w 2013.06.07 1 1 2013.11.07 9 8
112 Korea Seoul Miracle Clinic Mansik,Cho BHJ 31 F 1w,24w 2013.06.07 1 0 2013.11.11 3 4
113 Korea Seoul Miracle Clinic Mansik,Cho KSH 38 F 1w,24w 2013.06.07 1 0 2013.11.11 6 4
114 Korea Seoul Miracle Clinic Mansik,Cho LSH 32 F 1w,24w 2013.06.07 1 1 2013.11.05 2 3
115 Korea Seoul Miracle Clinic Mansik,Cho HKS 44 F 1w,24w 2013.06.08 1 1 2013.11.12 9 8
116 Korea Seoul Miracle Clinic Mansik,Cho JYB 30 F 1w,24w 2013.06.11 4 4 2013.11.13 9 9
117 Korea Seoul Miracle Clinic Mansik,Cho JYY 36 F 1w,24w 2013.06.11 3 3 2013.11.13 8 8
118 Korea Seoul Miracle Clinic Mansik,Cho KJW 39 F 1w,24w 2013.06.12 4 4 2013.11.14 8 7
119 Korea Seoul Miracle Clinic Mansik,Cho CYH 41 F 1w,24w 2013.06.14 4 4 2013.11.15 7 7
120 Korea Seoul Miracle Clinic Mansik,Cho HMY 39 F 1w,24w 2013.06.14 7 8 2013.11.15 8 7
121 Korea Seoul Miracle Clinic Mansik,Cho LKH 42 F 1w,24w 2013.06.14 7 7 2013.11.15 9 8
122 Korea Seoul Miracle Clinic Mansik,Cho LBJ 66 M 1w,24w 2013.06.14 7 8 2013.11.22 9 9
123 Korea Seoul Miracle Clinic Mansik,Cho KDW 34 M 1w,24w 2013.06.15 6 5 2013.11.22 9 8
124 Korea Seoul Miracle Clinic Mansik,Cho BSY 61 M 1w,24w 2013.06.15 3 2 2013.11.23 8 6
125 Korea Seoul Miracle Clinic Mansik,Cho LSH 66 M 1w,24w 2013.06.15 4 2 2013.11.22 4 6
126 Korea Seoul Miracle Clinic Mansik,Cho LSH 48 M 1w,24w 2013.06.16 4 2 2013.11.22 5 6
127 Korea Seoul Miracle Clinic Mansik,Cho LCH 42 M 1w,24w 2013.06.19 7 7 2013.11.23 7 7
128 Korea Seoul Miracle Clinic Mansik,Cho LTH 60 M 1w,24w 2013.06.19 3 2 2013.11.25 9 9
129 Korea Seoul Miracle Clinic Mansik,Cho JKH 43 F 1w,24w 2013.06.19 4 4 2013.11.27 8 7
62
“Winner Of
Nano Technology”
Total Hair Loss Solution
Appendix | P.
Appendix
■ Trial Patients Profile – Seoul Moram Clinic
Nationality Hospital Name Dr.Name
Patient N
ame
Age Sex Interval (Weeks) F/U Data Point (S) Point (O) F/U Date Point (S) Point (O)
132 Korea Seoul Moram Clinic Jiwon,Park KHT 35 F 1w,24w 2013.05.15 6 6 2013.10.30 8 8
133 Korea Seoul Moram Clinic Jiwon,Park BJH 37 F 1w,24w 2013.05.15 6 6 2013.10.31 9 8
134 Korea Seoul Moram Clinic Jiwon,Park LDJ 36 F 1w,24w 2013.05.15 5 5 2013.10.31 9 8
135 Korea Seoul Moram Clinic Jiwon,Park BJM 38 F 1w,24w 2013.05.15 7 7 2013.10.31 8 9
136 Korea Seoul Moram Clinic Jiwon,Park HCS 39 F 1w,24w 2013.05.16 6 6 2013.10.30 9 8
137 Korea Seoul Moram Clinic Jiwon,Park KDB 42 F 1w,24w 2013.05.16 5 5 2013.10.30 7 8
138 Korea Seoul Moram Clinic Jiwon,Park USJ 39 F 1w,24w 2013.05.20 7 7 2013.10.30 9 9
139 Korea Seoul Moram Clinic Jiwon,Park HAS 41 F 1w,24w 2013.05.20 6 6 2013.10.31 8 8
140 Korea Seoul Moram Clinic Jiwon,Park PYL 48 F 1w,24w 2013.05.20 2 2 2013.10.31 8 6
141 Korea Seoul Moram Clinic Jiwon,Park LHL 35 M 1w,24w 2013.05.22 3 3 2013.11.04 9 5
142 Korea Seoul Moram Clinic Jiwon,Park CYJ 40 F 1w,24w 2013.05.22 3 4 2013.11.04 9 5
143 Korea Seoul Moram Clinic Jiwon,Park CSM 51 M 1w,24w 2013.05.22 4 4 2013.11.05 9 8
144 Korea Seoul Moram Clinic Jiwon,Park KJS 29 F 1w,24w 2013.05.24 6 7 2013.10.31 8 9
145 Korea Seoul Moram Clinic Jiwon,Park KJJ 41 M 1w,24w 2013.05.24 2 2 2013.11.05 8 6
146 Korea Seoul Moram Clinic Jiwon,Park PYC 33 M 1w,24w 2013.05.25 1 0 2013.11.06 9 4
147 Korea Seoul Moram Clinic Jiwon,Park JYH 45 F 1w,24w 2013.05.25 0 0 2013.11.06 9 8
148 Korea Seoul Moram Clinic Jiwon,Park PJW 40 M 1w,24w 2013.05.25 0 1 2013.11.07 9 7
149 Korea Seoul Moram Clinic Jiwon,Park LKK 38 M 1w,24w 2013.05.25 3 3 2013.11.07 7 5
150 Korea Seoul Moram Clinic Jiwon,Park JMK 62 F 1w,24w 2013.05.27 3 3 2013.11.05 9 6
151 Korea Seoul Moram Clinic Jiwon,Park KSJ 43 M 1w,24w 2013.05.27 4 4 2013.11.07 9 6
152 Korea Seoul Moram Clinic Jiwon,Park KDE 33 M 1w,24w 2013.05.28 4 5 2013.11.06 9 8
153 Korea Seoul Moram Clinic Jiwon,Park SHJ 48 M 1w,24w 2013.05.28 3 2 2013.11.06 8 7
154 Korea Seoul Moram Clinic Jiwon,Park SHH 66 M 1w,24w 2013.05.28 2 2 2013.11.06 9 6
155 Korea Seoul Moram Clinic Jiwon,Park PJH 59 M 1w,24w 2013.05.28 2 2 2013.11.06 8 8
156 Korea Seoul Moram Clinic Jiwon,Park KSH 40 M 1w,24w 2013.05.28 4 5 2013.11.06 9 8
157 Korea Seoul Moram Clinic Jiwon,Park KMJ 44 F 1w,24w 2013.05.29 4 3 2013.11.06 9 9
158 Korea Seoul Moram Clinic Jiwon,Park NJH 59 M 1w,24w 2013.05.30 1 1 2013.11.08 9 4
159 Korea Seoul Moram Clinic Jiwon,Park SHS 21 F 1w,24w 2013.05.30 6 6 2013.11.11 7 7
160 Korea Seoul Moram Clinic Jiwon,Park SHJ 54 F 1w,24w 2013.05.30 4 4 2013.11.11 9 5
161 Korea Seoul Moram Clinic Jiwon,Park LSH 64 M 1w,24w 2013.05.31 2 2 2013.11.06 9 4
161 Korea Seoul Moram Clinic Jiwon,Park LSH 64 M 1w,24w 2013.05.31 2 2 2013.11.06 9 4
162 Korea Seoul Moram Clinic Jiwon,Park KDJ 61 M 1w,24w 2013.05.31 1 1 2013.11.06 9 3
163 Korea Seoul Moram Clinic Jiwon,Park CBR 63 M 1w,24w 2013.05.31 2 3 2013.11.07 2 2
164 Korea Seoul Moram Clinic Jiwon,Park KYB 40 M 1w,24w 2013.05.31 7 7 2013.11.07 9 8
165 Korea Seoul Moram Clinic Jiwon,Park LMY 51 M 1w,24w 2013.06.03 7 6 2013.11.06 8 8
166 Korea Seoul Moram Clinic Jiwon,Park JMY 71 M 1w,24w 2013.06.03 1 1 2013.11.06 7 7
167 Korea Seoul Moram Clinic Jiwon,Park KES 70 M 1w,24w 2013.06.04 1 1 2013.11.18 8 5
168 Korea Seoul Moram Clinic Jiwon,Park KSH 61 M 1w,24w 2013.06.04 1 0 2013.11.18 9 4
169 Korea Seoul Moram Clinic Jiwon,Park PJY 33 M 1w,24w 2013.06.05 4 3 2013.11.19 9 6
170 Korea Seoul Moram Clinic Jiwon,Park YHY 33 M 1w,24w 2013.06.05 3 3 2013.11.19 9 6
171 Korea Seoul Moram Clinic Jiwon,Park LJY 40 M 1w,24w 2013.06.07 2 2 2013.11.19 8 8
172 Korea Seoul Moram Clinic Jiwon,Park YHJ 21 M 1w,24w 2013.06.07 5 5 2013.11.20 9 8
173 Korea Seoul Moram Clinic Jiwon,Park LDE 37 M 1w,24w 2013.06.07 7 7 2013.11.22 9 9
174 Korea Seoul Moram Clinic Jiwon,Park IYE 20 M 1w,24w 2013.06.07 2 1 2013.11.22 8 9
175 Korea Seoul Moram Clinic Jiwon,Park LEJ 40 M 1w,24w 2013.06.10 5 5 2013.11.25 9 7
176 Korea Seoul Moram Clinic Jiwon,Park JSY 31 M 1w,24w 2013.06.11 4 4 2013.11.25 9 6
177 Korea Seoul Moram Clinic Jiwon,Park YHJ 63 M 1w,24w 2013.06.12 1 1 2013.11.25 8 7
178 Korea Seoul Moram Clinic Jiwon,Park KSJ 41 M 1w,24w 2013.06.12 3 3 2013.11.26 7 5
179 Korea Seoul Moram Clinic Jiwon,Park KHR 33 M 1w,24w 2013.06.12 1 1 2103.11.26 8 8
180 Korea Seoul Moram Clinic Jiwon,Park YSO 28 M 1w,24w 2013.06.13 2 2 2013.11.27 7 6
181 Korea Seoul Moram Clinic Jiwon,Park OJH 27 M 1w,24w 2013.06.14 3 3 2013.12.02 9 7
182 Korea Seoul Moram Clinic Jiwon,Park BKT 48 M 1w,24w 2013.06.14 3 3 2013.12.02 9 8
183 Korea Seoul Moram Clinic Jiwon,Park KJH 42 M 1w,24w 2013.06.14 3 3 2013.12.02 9 5
184 Korea Seoul Moram Clinic Jiwon,Park LYJ 38 M 1w,24w 2013.06.15 3 3 2013.12.10 7 7
185 Korea Seoul Moram Clinic Jiwon,Park UKS 33 M 1w,24w 2013.06.15 1 2 2013.12.10 9 8
186 Korea Seoul Moram Clinic Jiwon,Park MHJ 48 M 1w,24w 2013.06.15 3 3 2013.12.18 7 6
187 Korea Seoul Moram Clinic Jiwon,Park SCR 40 M 1w,24w 2013.06.15 2 2 2013.12.18 8 7
188 Korea Seoul Moram Clinic Jiwon,Park LSE 41 M 1w,24w 2013.06.15 4 4 2013.12.19 8 8
189 Korea Seoul Moram Clinic Jiwon,Park CYJ 49 M 1w,24w 2013.06.15 4 4 2013.12.19 9 6
190 Korea Seoul Moram Clinic Jiwon,Park KMJ 31 M 1w,24w 2013.06.18 4 4 2013.12.19 6 8
63
“Winner Of
Nano Technology”
Total Hair Loss Solution
Appendix | P.
Appendix
■ Trial Patients Profile – Seoul Tatoa Clinic
Nationality Hospital Name Dr.Name Patient Name Age Sex Interval (Weeks) F/U Data Point (S) Point (O) F/U Date Point (S) Point (O)
191 Korea Seoul Tatoa Clinic Sukmoon,Kang RHJ 52 F 1w,24w 2013.05.15 2 4 2013.10.30 8 8
192 Korea Seoul Tatoa Clinic Sukmoon,Kang LYJ 44 M 1w,24w 2013.05.15 2 2 2013.10.30 9 7
193 Korea Seoul Tatoa Clinic Sukmoon,Kang LJH 27 M 1w,24w 2013.05.16 4 4 2013.10.30 9 9
194 Korea Seoul Tatoa Clinic Sukmoon,Kang ACH 39 F 1w,24w 2013.05.20 4 4 2013.10.30 9 8
195 Korea Seoul Tatoa Clinic Sukmoon,Kang LJY 34 M 1w,24w 2013.05.20 4 4 2013.10.31 9 6
196 Korea Seoul Tatoa Clinic Sukmoon,Kang KSH 41 M 1w,24w 2013.05.20 7 7 2013.10.31 8 9
197 Korea Seoul Tatoa Clinic Sukmoon,Kang LMJ 42 M 1w,24w 2013.05.22 5 4 2013.11.04 7 8
198 Korea Seoul Tatoa Clinic Sukmoon,Kang LBH 49 F 1w,24w 2013.05.22 3 2 2013.11.04 8 9
199 Korea Seoul Tatoa Clinic Sukmoon,Kang KMJ 34 M 1w,24w 2013.05.22 7 5 2013.11.04 9 9
200 Korea Seoul Tatoa Clinic Sukmoon,Kang LHL 40 M 1w,24w 2013.05.22 5 5 2013.11.11 8 7
201 Korea Seoul Tatoa Clinic Sukmoon,Kang NKR 44 M 1w,24w 2013.05.23 7 7 2013.11.11 9 10
64
“Winner Of
Nano Technology”
Total Hair Loss Solution
Appendix | P.
Appendix
65
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Nano Technology”
Total Hair Loss Solution
Appendix | P.
Appendix
66
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Nano Technology”
Total Hair Loss Solution
Appendix | P.
Appendix
67
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Total Hair Loss Solution
Appendix | P.
Appendix
68
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Nano Technology”
Total Hair Loss Solution
Appendix | P.
Appendix
69
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Nano Technology”
Total Hair Loss Solution
Appendix | P.
Appendix
70
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Total Hair Loss Solution
Appendix | P.
Appendix
71
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Total Hair Loss Solution
Appendix | P.
Appendix
72
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Total Hair Loss Solution
Appendix | P.
Appendix
73
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Total Hair Loss Solution
Appendix | P.
Appendix
74
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Nano Technology”
Total Hair Loss Solution
Appendix | P.
Appendix
75
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Nano Technology”
Total Hair Loss Solution
Appendix | P.
Appendix
Before (0 week)
0.030mm
(0week) 93 hair
(24week)
0.104mm
(24week)
123 hair
Change of Hair Thickness
Change of Hair Quantity
After
Test Center : Bundang Seoul National University Hospital, Kyungbuk
National University KFDA, 40 Participants Test Completed
■ Clinical Phototrichogram Result
76
“Winner Of
Nano Technology”
Total Hair Loss Solution
Appendix | P.
Appendix
(0week) 87 hair (24week)
101 hair
(0week)
0.035mm
(24week)
0.095mm
Before
After
■ Clinical Phototrichogram Result
Change of Hair Thickness
Change of Hair Quantity
Test Center : Bundang Seoul National University Hospital, Kyungbuk
National University KFDA, 40 Participants Test Completed
77
“Winner Of
Nano Technology”
Total Hair Loss Solution
Appendix | P.
Appendix
(12week)
0.047mm
(0week)
0.030mm
(0week) 82 hair (24week)
105 hair
Before
After
■ Clinical Phototrichogram Result
Change of Hair Thickness
Change of Hair Quantity
Test Center : Bundang Seoul National University Hospital, Kyungbuk
National University KFDA, 40 Participants Test Completed
78
“Winner Of
Nano Technology”
Total Hair Loss Solution
Appendix | P.
Appendix
(12week)
0.075mm
(0week)
0.060mm
(0week)
103 hair
(24week)
119 hair
Before
After
■ Clinical Phototrichogram Result
Change of Hair Thickness
Change of Hair Quantity
Test Center : Bundang Seoul National University Hospital, Kyungbuk
National University KFDA, 40 Participants Test Completed
79
“Winner Of
Nano Technology”
Total Hair Loss Solution
Appendix | P.
Appendix
(12week)
0.085mm
(0week)
0.077mm
(0week) 92 hair (24week) 120
hair
Before
After
■ Clinical Phototrichogram Result
Change of Hair Thickness
Change of Hair Quantity
Test Center : Bundang Seoul National University Hospital, Kyungbuk
National University KFDA, 40 Participants Test Completed
Total Hair Loss Solution
WONTECH Co., Ltd.
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Hair Bang (Hair Boom) Clinical Research

  • 1. A B S T R A C T B O O K Hair Bang & Hair Boom Low Level Laser Therapy (LLLT) Clinical Research Studies Total Hair Loss Solution
  • 2. Hair Bang & Hair Boom Low Level Laser Therapy (LLLT) Clinical Research Studies Total Hair Loss Solution 2 “Winner Of Nano Technology” <Contents> 1. Summary (p.3) 2. Research 1 - Low-level light therapy for androgenetic alopecia: a 24-week, randomized, double-blind, sham device-controlled multicenter trial. (Hair Boom & Hair Bang Clinical Research-Performed by WONTECH and Bundang Seoul National University & Kyungbuk University Hospital) (p.4) 3. Research 2 - Efficacy and Safety of a Low-level Laser Device in the Treatment of Male and Female Pattern Hair Loss: A Multicenter, Randomized, Sham Device- controlled, Double-blind Study. (p.12) 4. Research 3 - The Growth of Human Scalp Hair in Females Using Visible Red Light Laser and LED Sources (p.26) 5. Research 4 - Low-Level Laser (Light) Therapy (LLLT) for Treatment of Hair Loss (p.35) 6. Research 5 - Low-level laser (Light) therapy (LLLT) in skin: stimulating, healing, restoring (p.44) 7. Hair Bang Trial - Hair Bang test in Korean clinics: Bun-dang Go-Woon Clinic, Seoul Miracle Clinic, Seoul Moram Clinic, Seoul Tatoa Clinic (Hair Boom & Hair Bang Test) (p.57) Appendix
  • 3. Hair Bang & Hair Boom Low Level Laser Therapy (LLLT) Clinical Research Studies Total Hair Loss Solution 3 “Winner Of Nano Technology” <Research Summury> Title Objective Result Research 1 Low-level light the rapy for androgen etic alopecia: a 24 -week, randomize d, double-blind, s ham device-contr olled multicenter t rial. To evaluate the efficacy and saf ety of LLLT (Hai r Bang & Hair B oom After 24 weeks of treatment, the LLLT group showed significantl y greater hair density than the sham device group. Mean hair di ameter improved statistically significantly more in the LLLT grou p than in the sham device group No serious adverse reactions were detected. Research 2 Efficacy and Safety of a Low-level Las er Device in the Tr eatment of Male a nd Female Pattern Hair Loss: A Multic enter, Randomized , Sham Device-con trolled, Double-bli nd Study To determine w hether treatme nt with a low le vel laser device increases termi nal hair density in both men an d women with pattern hair los s. Seventy-eight, 63, 49, and 79 subjects were randomized in four trials of 9-beam lasercomb treatment in female subjects, 12-bea m lasercomb treatment in female subjects, 7-beam lasercomb tr eatment in male subjects, and 9- and 12-beam lasercomb treat ment in male subjects. Higher percentage of laser-treated subje cts reported overall improvement of hair loss. Research 3 The Growth of Hu man Scalp Hair in Females Using Visi ble Red Light Lase r and LED Sources To define the s afety and physi ologic effects o f LLLT on femal es with androg enic alopecia. Forty-two patients completed the study (24 active, 18 sham). Th e active group received a “TOPHAT655” unit containing 21, 5 m W diode lasers (655 5 nm) and 30 LEDS (655 20 nm) Baseline hair counts were 228.2 133.4 (N ¼ 18) in the sham and 209.6 118.5 (N ¼ 24) in the active group (P ¼ 0.642). The percent hair increase over the duration of the study was 11.05 48.30 (N ¼ 1 8) for the sham group and 48.07 17.61 (N ¼ 24) for the active group (P < 0.001). This demonstrates a 37% increase in hair gro wth in the active treatment group as compared to the placebo group. Research 4 Low-Level Laser (L ight) Therapy (LLL T) for Treatment o f Hair Loss Pinar Avci et al (Lasers Surg M ed. 2014) This review surveys the evidence for low-level laser therapy (LLL T) applied to the scalp as a treatment for hair loss and discusse s possible mechanisms of actions. Research 5 Low-level laser (Li ght) therapy (LLLT) in skin: stimulating , healing, restoring This review will cover the use o f LLLT as possib ly the ultimate non-invasive ap proach to treati ng the skin. The application of LLLT to disorders of pigmentation may work both ways by producing both repigmentation of vitiligo, and de pigmentation of hyperpigmented lesions depending on the dosi metric parameters. The introduction of LED array-based devices has simplified the application to large areas of skin.
  • 4. 4 “Winner Of Nano Technology” 2. Research 1 | P. Total Hair Loss Solution 2. Research Ⅰ Lee Seok Jong, Huh Chang Hun et al. Low-level light therapy for androgenetic alopecia: a 24-week, randomized, double-blind, sham device-controlled multicenter trial. Dermatol Surg. 2013;1–7
  • 5. 5 “Winner Of Nano Technology” 3. Research 2 | P. Total Hair Loss Solution
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  • 12. 12 “Winner Of Nano Technology” 3. Research 2 | P. Total Hair Loss Solution 3. Research Ⅱ Joaquin J. Jimenez, Tongyu C. Wikramanayake, Wilma Bergfeld, Maria Hordinsky, Janet G. Hickman, Michael R. Hamblin and Lawrence A. Schachner. Efficacy and Safety of a Low-level Laser Device in the Treatment of Male and Female Pattern Hair Loss: A Multicenter, Randomized, Sham Device-controlled, Double-blind Study. Am J Clin Dermatol. (2014) 15:115–127
  • 13. 13 “Winner Of Nano Technology” 4. Research 3 | P. Total Hair Loss Solution
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  • 25. 25 “Winner Of Nano Technology” 4. Research 3 | P. Total Hair Loss Solution
  • 26. 26 “Winner Of Nano Technology” 4. Research 3 | P. Total Hair Loss Solution 4. Research Ⅲ Raymond J. Lanzafame, Raymond R. Blanche, Richard P. Chiacchierini, Eric R. Kazmirek, and Jeffrey A. Sklar. The Growth of Human Scalp Hair in Females Using Visible Red Light Laser and LED Sources. Lasers in Surgery and Medicine 46:601– 607 (2014)
  • 27. 27 “Winner Of Nano Technology” 4. Research 3 | P. Total Hair Loss Solution
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  • 34. 34 “Winner Of Nano Technology” 5. Research 4 | P. Total Hair Loss Solution 5. Research Ⅳ Pinar Avci, Gaurav K. Gupta, Jason Clark, Norbert Wikonkal, and Michael R. Hamblin. Low-Level Laser (Light) Therapy (LLLT) for Treatment of Hair Loss. Lasers Surg Med. 2014 February ; 46(2): 144–151
  • 35. 35 “Winner Of Nano Technology” 5. Research 4 | P. Total Hair Loss Solution
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  • 43. 43 “Winner Of Nano Technology” 6. Research 5 | P. Total Hair Loss Solution 6. Research Ⅴ Pinar Avci, Asheesh Gupta, Magesh Sadasivam, Daniela Vecchio, Zeev Pam, Nadav Pam, and Michael R Hamblin. Low-level laser (Light) therapy (LLLT) in skin: stimulating, healing, restoring. Semin Cutan Med Surg. 2013 March ; 32(1): 41–52.
  • 44. 44 “Winner Of Nano Technology” 6. Research 5 | P. Total Hair Loss Solution
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  • 56. 56 “Winner Of Nano Technology” Total Hair Loss Solution 7. Hair Bang Trial | P. 7. Hair Bang Trial Hair Boom & Hair Bang test in three Korean clinics: Bun-dang Go-Woon Clinic, Seoul Miracle Clinic, Seoul Moram Clinic. (Hair Boom & Hair Bang Test)
  • 57. 57 “Winner Of Nano Technology” Total Hair Loss Solution 7. Hair Bang Trial | P. 7. Hair Bang Trial Background Background Nowadays, more and more people suffer from the hair loss and they desire to get their hair back. Hairbang is a non- invasive low level laser system for hair regrowth and hair regeneration. This is equipped with highly effective 27LDs and 42LEDs modules to maximize the treatment result. Androgenetic alopecia (AGA) is a common disorder affecting men and women. Finasteride and Minoxidil are well-known. Effective treatment methods. Patient who exhibit a poor response to these methods have no additional adequate treatment modalities Treatment Period 2013.05~2013.12 Satisfaction Assessment 24 weeks after treatment completion Total Patients201 (AGA, Systemic Disease, Korean 100%) Gender Ratio Men 75%, Women 25% Objective To verify the efficacy and safety of Hair Bang, we recruit 200 participants simultaneously at three Korean clinics in a same way. Result • 198 of 201 (99%) participants responded the result was clinically effective. • 109 of 201 (54%), 72 of 201 (36%) participants responded their condition had been improved • 11 participants who volunteered to take a digital photograph recognized that their average 2 2 hair had grown up. Hair Bang Laser Type LD/LED Function(mode) Laser, Vibration Wavelength 630nm/650nm/660nm Module LD 27 + LED 42 Treatment Time 18 ■ Research Summary irradiate the whole scalp widely  Activates hair follicle Stimulate and widen capillary Vessel  Improves blood flow and blood circulation Activate blood flow  Supplies sufficient nutrition and delivers Oxygen ■ Product Detail ■ Treatment Principle
  • 58. 58 “Winner Of Nano Technology” 7. Hair Bang Trial | P. ■ Trial Detail 7. Hair Bang Trial Patient Population • Patient global assessment was measured on a visual analogue scale (designation 0 indicating no growth or aggra vation and 10 indicating 100% restoration of AGA at the 1 and 24 weeks visits) • The investigator assessed the patients using visual inspection and digital photographs at the baseline and 1 week and 24 weeks visits • 200 patients with moderate to severe • Excluded individuals who had used topical or systemic medication affecting hair growth, such as Finasteride, Minox idil within past 6 months. • Patients who had hair disorder other than AGA or systemic diseases. Methods • Hamilton Classification of Ⅲ to Ⅶ for men or Ludwing classification of Ⅰ to Ⅲ for women. • The ‘HairBang’ is a helmet type-3R LLLT device with a light source consisting of light-emitting diodes (LEDs) emitti ng wavelength of 630nm,660nm and laser diodes(LDs) emitting 650nm. • Diodes run simultaneously through six cycles, each consisting of 2 minutes 50 seconds on and 10 seconds off • Patients were instructed how to operate each device at the baseline visit and scheduled to use it for 18 minutes on ce a daily for 24 weeks. • Follow –up visit were scheduled 1 and 24 weeks after the study began to evaluate subjects Assessment • Using a Phototrichogram • Global Assessment of Hair regrowth according to the patient and investigator. ■ Result Score Patient Observer 0 3 3 1 11 10 2 22 37 3 23 34 4 24 37 5 42 30 6 33 27 7 24 17 8 15 6 9 4 0 Total 201 201 Patient Observer Average 4.73 4.04 Patient Score Patient score average 0 10 20 30 40 50 5 6 7 8 9 Patient Observer Patient & Observer, having the score above 5 Patient No. 1w 24w regrowth 106 87 114 27 107 68 91 23 108 57 92 35 109 85 102 17 110 75 101 26 111 57 96 39 112 68 81 13 113 83 101 18 114 83 101 18 115 74 85 11 116 106 121 15 Count Regrowth Average 22 Hair Growth 1w 0 50 100 150 106 108 110 112 114 116 1w 24w Patient no. NumberofHair Comparison of Hair Growth with Baseline (1w)
  • 59. 59 “Winner Of Nano Technology” Total Hair Loss Solution 7. Hair Bang Trial | P. Appendix Trial Patients Profile
  • 60. 60 “Winner Of Nano Technology” Total Hair Loss Solution Appendix | P. Appendix Nationality Hospital Name Dr.Name Patient Na me Age Sex Interval (We eks) F/U Data Point (S) Point (O) F/U Date Point (S) Point (O) 1 Korea Bundang Gowoon Clinic SooMi, Kim BSY 55 M 1w,24w 2013.04.20 1 1 2013.10.04 9 9 2 Korea Bundang Gowoon Clinic SooMi, Kim KBJ 49 M 1w,24w 2013.05.06 0 2 2013.10.14 8 8 3 Korea Bundang Gowoon Clinic SooMi, Kim CMS 44 M 1w,24w 2013.05.06 0 2 2013.10.14 8 7 4 Korea Bundang Gowoon Clinic SooMi, Kim SHS 31 M 1w,24w 2013.05.08 0 1 2013.10.16 8 7 5 Korea Bundang Gowoon Clinic SooMi, Kim KBJ 36 M 1w,24w 2013.05.08 0 3 2013.10.16 7 7 6 Korea Bundang Gowoon Clinic SooMi, Kim K이 60 M 1w,24w 2013.05.08 4 5 2013.10.16 7 8 7 Korea Bundang Gowoon Clinic SooMi, Kim KUH 46 M 1w,24w 2013.05.13 6 5 2013.10.21 7 8 8 Korea Bundang Gowoon Clinic SooMi, Kim HIH 39 M 1w,24w 2013.05.15 3 2 2013.10.24 6 7 9 Korea Bundang Gowoon Clinic SooMi, Kim YEL 55 M 1w,24w 2013.05.13 1 2 2013.10.21 6 5 10 Korea Bundang Gowoon Clinic SooMi, Kim KJY 29 M 1w,24w 2013.05.05 1 2 2013.10.14 5 6 11 Korea Bundang Gowoon Clinic SooMi, Kim KDB 50 M 1w,24w 2013.05.06 1 0 2013.10.14 7 6 12 Korea Bundang Gowoon Clinic SooMi, Kim KWJ 31 M 1w,24w 2013.05.07 1 1 2013.10.15 7 8 13 Korea Bundang Gowoon Clinic SooMi, Kim KEB 42 M 1w,24w 2013.05.08 0 1 2013.10.18 8 8 14 Korea Bundang Gowoon Clinic SooMi, Kim KEJ 56 M 1w,24w 2013.05.08 2 2 2013.10.18 5 7 15 Korea Bundang Gowoon Clinic SooMi, Kim KHK 62 M 1w,24w 2013.05.10 2 3 2013.10.18 7 6 16 Korea Bundang Gowoon Clinic SooMi, Kim NSR 64 M 1w,24w 2013.05.13 1 2 2013.10.21 8 8 17 Korea Bundang Gowoon Clinic SooMi, Kim NHS 40 M 1w,24w 2013.05.15 1 0 2013.10.23 9 8 18 Korea Bundang Gowoon Clinic SooMi, Kim PSY 59 M 1w,24w 2013.05.15 0 1 2013.10.23 9 9 19 Korea Bundang Gowoon Clinic SooMi, Kim PSJ 41 M 1w,24w 2013.05.10 6 6 2013.10.25 9 8 20 Korea Bundang Gowoon Clinic SooMi, Kim BJO 32 M 1w,24w 2013.05.12 4 3 2013.10.28 9 9 21 Korea Bundang Gowoon Clinic SooMi, Kim SYJ 66 M 1w,24w 2013.05.13 2 3 2013.10.28 10 9 22 Korea Bundang Gowoon Clinic SooMi, Kim SHJ 21 M 1w,24w 2013.05.13 3 3 2013.10.28 8 7 23 Korea Bundang Gowoon Clinic SooMi, Kim YSJ 43 M 1w,24w 2013.05.13 5 4 2013.10.28 9 9 24 Korea Bundang Gowoon Clinic SooMi, Kim OIS 52 M 1w,24w 2013.05.16 4 4 2013.10.30 8 8 25 Korea Bundang Gowoon Clinic SooMi, Kim YHJ 38 M 1w,24w 2013.05.16 2 2 2013.10.30 9 9 26 Korea Bundang Gowoon Clinic SooMi, Kim YJH 39 M 1w,24w 2013.05.17 7 6 2013.10.30 8 9 27 Korea Bundang Gowoon Clinic SooMi, Kim LSM 57 M 1w,24w 2013.05.18 4 5 2013.10.30 7 7 28 Korea Bundang Gowoon Clinic SooMi, Kim LYS 42 M 1w,24w 2013.05.18 3 3 2013.10.30 8 7 29 Korea Bundang Gowoon Clinic SooMi, Kim LWJ 22 M 1w,24w 2013.05.19 6 6 2013.10.30 9 8 30 Korea Bundang Gowoon Clinic SooMi, Kim LYJ 51 M 1w,24w 2013.05.19 1 1 2013.10.31 6 7 31 Korea Bundang Gowoon Clinic SooMi, Kim ISC 21 M 1w,24w 2013.05.20 5 5 2013.10.31 7 7 32 Korea Bundang Gowoon Clinic SooMi, Kim JHL 42 M 1w,24w 2013.05.21 4 4 2013.10.31 9 9 33 Korea Bundang Gowoon Clinic SooMi, Kim JYJ 22 M 1w,24w 2013.05.22 3 3 2013.10.31 8 8 34 Korea Bundang Gowoon Clinic SooMi, Kim JYB 67 F 1w,24w 2013.05.23 4 3 2013.11.02 8 7 35 Korea Bundang Gowoon Clinic SooMi, Kim JEH 47 M 1w,24w 2013.05.24 1 1 2013.11.02 9 7 36 Korea Bundang Gowoon Clinic SooMi, Kim JYJ 51 M 1w,24w 2013.05.25 5 4 2013.11.02 9 8 37 Korea Bundang Gowoon Clinic SooMi, Kim JYJ 61 M 1w,24w 2013.05.06 2 3 2013.11.02 5 5 38 Korea Bundang Gowoon Clinic SooMi, Kim CHJ 59 M 1w,24w 2013.05.06 2 3 2013.11.02 7 6 39 Korea Bundang Gowoon Clinic SooMi, Kim HAS 66 F 1w,24w 2013.05.06 3 3 2013.11.02 7 6 40 Korea Bundang Gowoon Clinic SooMi, Kim HYE 40 M 1w,24w 2013.05.08 3 3 2013.11.05 7 6 41 Korea Bundang Gowoon Clinic SooMi, Kim KEJ 69 M 1w,24w 2013.05.08 1 1 2013.11.05 5 5 42 Korea Bundang Gowoon Clinic SooMi, Kim KDE 53 M 1w,24w 2013.05.08 4 4 2013.11.05 9 9 43 Korea Bundang Gowoon Clinic SooMi, Kim KMH 43 M 1w,24w 2013.05.13 3 3 2013.11.08 8 8 44 Korea Bundang Gowoon Clinic SooMi, Kim KEJ 50 M 1w,24w 2013.05.15 3 3 2013.11.10 7 8 45 Korea Bundang Gowoon Clinic SooMi, Kim KHS 36 M 1w,24w 2013.05.15 4 4 2013.11.10 7 6 46 Korea Bundang Gowoon Clinic SooMi, Kim NMY 51 M 1w,24w 2013.05.24 2 2 2013.12.02 8 7 47 Korea Bundang Gowoon Clinic SooMi, Kim PKM 65 M 1w,24w 2013.05.24 3 4 2013.12.02 9 8 48 Korea Bundang Gowoon Clinic SooMi, Kim PYL 69 F 1w,24w 2013.06.03 3 4 2013.12.12 9 9 49 Korea Bundang Gowoon Clinic SooMi, Kim PJH 48 M 1w,24w 2013.06.03 4 3 2013.12.12 9 9 50 Korea Bundang Gowoon Clinic SooMi, Kim PHJ 32 M 1w,24w 2013.06.04 2 2 2013.12.12 9 9 51 Korea Bundang Gowoon Clinic SooMi, Kim SHJ 50 M 1w,24w 2013.06.04 2 2 2013.12.16 8 8 52 Korea Bundang Gowoon Clinic SooMi, Kim SSB 31 M 1w,24w 2013.06.04 1 1 2013.12.16 7 7 53 Korea Bundang Gowoon Clinic SooMi, Kim UDJ 30 M 1w,24w 2013.06.05 2 3 2013.12.17 7 6 54 Korea Bundang Gowoon Clinic SooMi, Kim USJ 44 M 1w,24w 2013.06.05 4 4 2013.12.17 8 8 55 Korea Bundang Gowoon Clinic SooMi, Kim YNR 67 M 1w,24w 2013.06.10 2 2 2013.12.18 5 5 56 Korea Bundang Gowoon Clinic SooMi, Kim LSM 54 M 1w,24w 2013.06.11 4 4 2013.12.18 6 6 57 Korea Bundang Gowoon Clinic SooMi, Kim LYS 46 M 1w,24w 2013.06.12 1 1 2013.12.18 6 6 58 Korea Bundang Gowoon Clinic SooMi, Kim LJW 48 M 1w,24w 2013.06.13 3 2 2013.12.18 7 7 59 Korea Bundang Gowoon Clinic SooMi, Kim LHR 32 M 1w,24w 2013.06.13 0 0 2013.12.18 5 5 ■ Trial Patients Profile – Bundang Gowoon Clinic
  • 61. 61 “Winner Of Nano Technology” Total Hair Loss Solution Appendix | P. Appendix ■ Trial Patients Profile – Seoul Miracle Clinic Nationality Hospital Name Dr.Name Patient Name Age Sex Interval (Weeks) F/U Data Point (S) Point (O) F/U Date Point (S) Point (O) 60 Korea Seoul Miracle Clinic Mansik,Cho KDE 51 M 1w,24w 2013.04.20 1 1 2013.10.14 7 8 61 Korea Seoul Miracle Clinic Mansik,Cho KMJ 60 M 1w,24w 2013.04.20 1 1 2013.10.14 8 8 62 Korea Seoul Miracle Clinic Mansik,Cho KAN 66 M 1w,24w 2013.04.20 0 1 2013.10.14 7 7 63 Korea Seoul Miracle Clinic Mansik,Cho KBK 64 M 1w,24w 2013.04.20 0 1 2013.10.11 7 6 64 Korea Seoul Miracle Clinic Mansik,Cho KAJ 55 F 1w,24w 2013.04.23 4 4 2013.10.16 8 8 65 Korea Seoul Miracle Clinic Mansik,Cho NJH 51 M 1w,24w 2013.04.23 0 0 2013.10.16 6 5 66 Korea Seoul Miracle Clinic Mansik,Cho NHR 41 M 1w,24w 2013.04.24 1 1 2013.10.21 7 5 67 Korea Seoul Miracle Clinic Mansik,Cho PSE 65 M 1w,24w 2013.04.24 0 0 2013.10.24 5 5 68 Korea Seoul Miracle Clinic Mansik,Cho PJS 71 M 1w,24w 2013.04.24 0 0 2013.10.21 7 5 69 Korea Seoul Miracle Clinic Mansik,Cho SHS 23 M 1w,24w 2013.04.25 3 3 2013.10.11 9 8 70 Korea Seoul Miracle Clinic Mansik,Cho KEY 63 M 1w,24w 2013.04.25 2 2 2013.10.11 7 6 71 Korea Seoul Miracle Clinic Mansik,Cho SDI 71 M 1w,24w 2013.04.27 1 1 2013.10.11 4 4 72 Korea Seoul Miracle Clinic Mansik,Cho SHS 45 M 1w,24w 2013.04.27 2 2 2013.10.14 6 4 73 Korea Seoul Miracle Clinic Mansik,Cho LMA 35 M 1w,24w 2013.04.27 2 2 2013.10.15 9 8 74 Korea Seoul Miracle Clinic Mansik,Cho LMY 64 F 1w,24w 2013.04.27 2 1 2013.10.14 8 7 75 Korea Seoul Miracle Clinic Mansik,Cho LYJ 40 M 1w,24w 2013.04.30 1 1 2013.10.14 5 3 76 Korea Seoul Miracle Clinic Mansik,Cho GSH 62 M 1w,24w 2013.05.01 3 3 2013.10.17 9 9 77 Korea Seoul Miracle Clinic Mansik,Cho KKY 40 M 1w,24w 2013.05.02 5 5 2013.10.17 8 8 78 Korea Seoul Miracle Clinic Mansik,Cho KGR 49 M 1w,24w 2013.05.02 1 1 2013.10.16 8 8 79 Korea Seoul Miracle Clinic Mansik,Cho KMS 45 M 1w,24w 2013.05.03 4 4 2013.10.16 7 6 80 Korea Seoul Miracle Clinic Mansik,Cho KSH 33 M 1w,24w 2013.05.03 6 6 2013.10.17 9 9 81 Korea Seoul Miracle Clinic Mansik,Cho KYS 61 M 1w,24w 2013.05.03 4 5 2013.10.17 9 7 82 Korea Seoul Miracle Clinic Mansik,Cho KYN 34 M 1w,24w 2013.05.03 4 5 2013.10.18 9 8 83 Korea Seoul Miracle Clinic Mansik,Cho KEY 51 M 1w,24w 2013.05.04 2 2 2013.10.17 9 8 84 Korea Seoul Miracle Clinic Mansik,Cho KJE 40 M 1w,24w 2013.05.04 3 2 2013.10.17 8 9 85 Korea Seoul Miracle Clinic Mansik,Cho SYK 52 M 1w,24w 2013.05.07 1 1 2013.10.22 8 8 86 Korea Seoul Miracle Clinic Mansik,Cho YSM 33 M 1w,24w 2013.05.08 6 6 2013.10.21 9 9 87 Korea Seoul Miracle Clinic Mansik,Cho LJY 49 M 1w,24w 2013.05.08 2 2 2013.10.21 9 9 88 Korea Seoul Miracle Clinic Mansik,Cho LHS 68 M 1w,24w 2013.05.10 1 3 2013.10.21 4 4 89 Korea Seoul Miracle Clinic Mansik,Cho CYJ 50 M 1w,24w 2013.05.22 2 2 2013.10.22 8 8 90 Korea Seoul Miracle Clinic Mansik,Cho HSY 62 M 1w,24w 2013.05.22 0 0 2013.10.24 9 6 91 Korea Seoul Miracle Clinic Mansik,Cho KRK 42 M 1w,24w 2013.05.22 3 3 2013.10.31 8 8 92 Korea Seoul Miracle Clinic Mansik,Cho KYJ 68 M 1w,24w 2013.05.22 2 2 2013.10.31 8 6 93 Korea Seoul Miracle Clinic Mansik,Cho KTK 64 M 1w,24w 2013.05.24 1 1 2013.10.30 6 6 94 Korea Seoul Miracle Clinic Mansik,Cho NSY 61 M 1w,24w 2013.05.24 2 3 2013.10.31 9 7 95 Korea Seoul Miracle Clinic Mansik,Cho LHJ 47 F 1w,24w 2013.05.25 7 5 2013.10.31 8 9 96 Korea Seoul Miracle Clinic Mansik,Cho JYJ 40 F 1w,24w 2013.05.28 5 5 2013.10.31 8 8 97 Korea Seoul Miracle Clinic Mansik,Cho KSH 44 M 1w,24w 2013.05.28 4 4 2013.11.01 9 9 98 Korea Seoul Miracle Clinic Mansik,Cho HCH 46 M 1w,24w 2013.05.28 7 6 2013.11.02 9 9 99 Korea Seoul Miracle Clinic Mansik,Cho KHJ 40 M 1w,24w 2013.05.29 5 5 2013.11.10 8 8 100 Korea Seoul Miracle Clinic Mansik,Cho RHM 52 M 1w,24w 2013.05.29 1 2 2013.11.11 3 4 101 Korea Seoul Miracle Clinic Mansik,Cho WTY 47 F 1w,24w 2013.05.30 2 1 2013.11.05 9 9 102 Korea Seoul Miracle Clinic Mansik,Cho LSH 46 F 1w,24w 2013.05.31 3 3 2013.11.05 9 9 103 Korea Seoul Miracle Clinic Mansik,Cho JHH 31 F 1w,24w 2013.06.01 2 2 2013.11.04 9 9 104 Korea Seoul Miracle Clinic Mansik,Cho PDH 30 F 1w,24w 2013.06.01 1 1 2013.11.04 8 8 105 Korea Seoul Miracle Clinic Mansik,Cho MJH 38 F 1w,24w 2013.06.01 5 5 2013.11.04 7 7 106 Korea Seoul Miracle Clinic Mansik,Cho syj 34 F 1w,24w 2013.06.04 6 6 2013.11.06 7 7 107 Korea Seoul Miracle Clinic Mansik,Cho LJK 31 F 1w,24w 2013.06.04 4 4 2013.11.07 6 5 108 Korea Seoul Miracle Clinic Mansik,Cho JBJ 49 F 1w,24w 2013.06.04 4 4 2013.11.07 6 5 109 Korea Seoul Miracle Clinic Mansik,Cho HSJ 40 F 1w,24w 2013.06.05 1 2 2013.11.07 8 7 110 Korea Seoul Miracle Clinic Mansik,Cho KJO 33 F 1w,24w 2013.06.06 2 2 2013.11.07 8 8 111 Korea Seoul Miracle Clinic Mansik,Cho SYH 30 F 1w,24w 2013.06.07 1 1 2013.11.07 9 8 112 Korea Seoul Miracle Clinic Mansik,Cho BHJ 31 F 1w,24w 2013.06.07 1 0 2013.11.11 3 4 113 Korea Seoul Miracle Clinic Mansik,Cho KSH 38 F 1w,24w 2013.06.07 1 0 2013.11.11 6 4 114 Korea Seoul Miracle Clinic Mansik,Cho LSH 32 F 1w,24w 2013.06.07 1 1 2013.11.05 2 3 115 Korea Seoul Miracle Clinic Mansik,Cho HKS 44 F 1w,24w 2013.06.08 1 1 2013.11.12 9 8 116 Korea Seoul Miracle Clinic Mansik,Cho JYB 30 F 1w,24w 2013.06.11 4 4 2013.11.13 9 9 117 Korea Seoul Miracle Clinic Mansik,Cho JYY 36 F 1w,24w 2013.06.11 3 3 2013.11.13 8 8 118 Korea Seoul Miracle Clinic Mansik,Cho KJW 39 F 1w,24w 2013.06.12 4 4 2013.11.14 8 7 119 Korea Seoul Miracle Clinic Mansik,Cho CYH 41 F 1w,24w 2013.06.14 4 4 2013.11.15 7 7 120 Korea Seoul Miracle Clinic Mansik,Cho HMY 39 F 1w,24w 2013.06.14 7 8 2013.11.15 8 7 121 Korea Seoul Miracle Clinic Mansik,Cho LKH 42 F 1w,24w 2013.06.14 7 7 2013.11.15 9 8 122 Korea Seoul Miracle Clinic Mansik,Cho LBJ 66 M 1w,24w 2013.06.14 7 8 2013.11.22 9 9 123 Korea Seoul Miracle Clinic Mansik,Cho KDW 34 M 1w,24w 2013.06.15 6 5 2013.11.22 9 8 124 Korea Seoul Miracle Clinic Mansik,Cho BSY 61 M 1w,24w 2013.06.15 3 2 2013.11.23 8 6 125 Korea Seoul Miracle Clinic Mansik,Cho LSH 66 M 1w,24w 2013.06.15 4 2 2013.11.22 4 6 126 Korea Seoul Miracle Clinic Mansik,Cho LSH 48 M 1w,24w 2013.06.16 4 2 2013.11.22 5 6 127 Korea Seoul Miracle Clinic Mansik,Cho LCH 42 M 1w,24w 2013.06.19 7 7 2013.11.23 7 7 128 Korea Seoul Miracle Clinic Mansik,Cho LTH 60 M 1w,24w 2013.06.19 3 2 2013.11.25 9 9 129 Korea Seoul Miracle Clinic Mansik,Cho JKH 43 F 1w,24w 2013.06.19 4 4 2013.11.27 8 7
  • 62. 62 “Winner Of Nano Technology” Total Hair Loss Solution Appendix | P. Appendix ■ Trial Patients Profile – Seoul Moram Clinic Nationality Hospital Name Dr.Name Patient N ame Age Sex Interval (Weeks) F/U Data Point (S) Point (O) F/U Date Point (S) Point (O) 132 Korea Seoul Moram Clinic Jiwon,Park KHT 35 F 1w,24w 2013.05.15 6 6 2013.10.30 8 8 133 Korea Seoul Moram Clinic Jiwon,Park BJH 37 F 1w,24w 2013.05.15 6 6 2013.10.31 9 8 134 Korea Seoul Moram Clinic Jiwon,Park LDJ 36 F 1w,24w 2013.05.15 5 5 2013.10.31 9 8 135 Korea Seoul Moram Clinic Jiwon,Park BJM 38 F 1w,24w 2013.05.15 7 7 2013.10.31 8 9 136 Korea Seoul Moram Clinic Jiwon,Park HCS 39 F 1w,24w 2013.05.16 6 6 2013.10.30 9 8 137 Korea Seoul Moram Clinic Jiwon,Park KDB 42 F 1w,24w 2013.05.16 5 5 2013.10.30 7 8 138 Korea Seoul Moram Clinic Jiwon,Park USJ 39 F 1w,24w 2013.05.20 7 7 2013.10.30 9 9 139 Korea Seoul Moram Clinic Jiwon,Park HAS 41 F 1w,24w 2013.05.20 6 6 2013.10.31 8 8 140 Korea Seoul Moram Clinic Jiwon,Park PYL 48 F 1w,24w 2013.05.20 2 2 2013.10.31 8 6 141 Korea Seoul Moram Clinic Jiwon,Park LHL 35 M 1w,24w 2013.05.22 3 3 2013.11.04 9 5 142 Korea Seoul Moram Clinic Jiwon,Park CYJ 40 F 1w,24w 2013.05.22 3 4 2013.11.04 9 5 143 Korea Seoul Moram Clinic Jiwon,Park CSM 51 M 1w,24w 2013.05.22 4 4 2013.11.05 9 8 144 Korea Seoul Moram Clinic Jiwon,Park KJS 29 F 1w,24w 2013.05.24 6 7 2013.10.31 8 9 145 Korea Seoul Moram Clinic Jiwon,Park KJJ 41 M 1w,24w 2013.05.24 2 2 2013.11.05 8 6 146 Korea Seoul Moram Clinic Jiwon,Park PYC 33 M 1w,24w 2013.05.25 1 0 2013.11.06 9 4 147 Korea Seoul Moram Clinic Jiwon,Park JYH 45 F 1w,24w 2013.05.25 0 0 2013.11.06 9 8 148 Korea Seoul Moram Clinic Jiwon,Park PJW 40 M 1w,24w 2013.05.25 0 1 2013.11.07 9 7 149 Korea Seoul Moram Clinic Jiwon,Park LKK 38 M 1w,24w 2013.05.25 3 3 2013.11.07 7 5 150 Korea Seoul Moram Clinic Jiwon,Park JMK 62 F 1w,24w 2013.05.27 3 3 2013.11.05 9 6 151 Korea Seoul Moram Clinic Jiwon,Park KSJ 43 M 1w,24w 2013.05.27 4 4 2013.11.07 9 6 152 Korea Seoul Moram Clinic Jiwon,Park KDE 33 M 1w,24w 2013.05.28 4 5 2013.11.06 9 8 153 Korea Seoul Moram Clinic Jiwon,Park SHJ 48 M 1w,24w 2013.05.28 3 2 2013.11.06 8 7 154 Korea Seoul Moram Clinic Jiwon,Park SHH 66 M 1w,24w 2013.05.28 2 2 2013.11.06 9 6 155 Korea Seoul Moram Clinic Jiwon,Park PJH 59 M 1w,24w 2013.05.28 2 2 2013.11.06 8 8 156 Korea Seoul Moram Clinic Jiwon,Park KSH 40 M 1w,24w 2013.05.28 4 5 2013.11.06 9 8 157 Korea Seoul Moram Clinic Jiwon,Park KMJ 44 F 1w,24w 2013.05.29 4 3 2013.11.06 9 9 158 Korea Seoul Moram Clinic Jiwon,Park NJH 59 M 1w,24w 2013.05.30 1 1 2013.11.08 9 4 159 Korea Seoul Moram Clinic Jiwon,Park SHS 21 F 1w,24w 2013.05.30 6 6 2013.11.11 7 7 160 Korea Seoul Moram Clinic Jiwon,Park SHJ 54 F 1w,24w 2013.05.30 4 4 2013.11.11 9 5 161 Korea Seoul Moram Clinic Jiwon,Park LSH 64 M 1w,24w 2013.05.31 2 2 2013.11.06 9 4 161 Korea Seoul Moram Clinic Jiwon,Park LSH 64 M 1w,24w 2013.05.31 2 2 2013.11.06 9 4 162 Korea Seoul Moram Clinic Jiwon,Park KDJ 61 M 1w,24w 2013.05.31 1 1 2013.11.06 9 3 163 Korea Seoul Moram Clinic Jiwon,Park CBR 63 M 1w,24w 2013.05.31 2 3 2013.11.07 2 2 164 Korea Seoul Moram Clinic Jiwon,Park KYB 40 M 1w,24w 2013.05.31 7 7 2013.11.07 9 8 165 Korea Seoul Moram Clinic Jiwon,Park LMY 51 M 1w,24w 2013.06.03 7 6 2013.11.06 8 8 166 Korea Seoul Moram Clinic Jiwon,Park JMY 71 M 1w,24w 2013.06.03 1 1 2013.11.06 7 7 167 Korea Seoul Moram Clinic Jiwon,Park KES 70 M 1w,24w 2013.06.04 1 1 2013.11.18 8 5 168 Korea Seoul Moram Clinic Jiwon,Park KSH 61 M 1w,24w 2013.06.04 1 0 2013.11.18 9 4 169 Korea Seoul Moram Clinic Jiwon,Park PJY 33 M 1w,24w 2013.06.05 4 3 2013.11.19 9 6 170 Korea Seoul Moram Clinic Jiwon,Park YHY 33 M 1w,24w 2013.06.05 3 3 2013.11.19 9 6 171 Korea Seoul Moram Clinic Jiwon,Park LJY 40 M 1w,24w 2013.06.07 2 2 2013.11.19 8 8 172 Korea Seoul Moram Clinic Jiwon,Park YHJ 21 M 1w,24w 2013.06.07 5 5 2013.11.20 9 8 173 Korea Seoul Moram Clinic Jiwon,Park LDE 37 M 1w,24w 2013.06.07 7 7 2013.11.22 9 9 174 Korea Seoul Moram Clinic Jiwon,Park IYE 20 M 1w,24w 2013.06.07 2 1 2013.11.22 8 9 175 Korea Seoul Moram Clinic Jiwon,Park LEJ 40 M 1w,24w 2013.06.10 5 5 2013.11.25 9 7 176 Korea Seoul Moram Clinic Jiwon,Park JSY 31 M 1w,24w 2013.06.11 4 4 2013.11.25 9 6 177 Korea Seoul Moram Clinic Jiwon,Park YHJ 63 M 1w,24w 2013.06.12 1 1 2013.11.25 8 7 178 Korea Seoul Moram Clinic Jiwon,Park KSJ 41 M 1w,24w 2013.06.12 3 3 2013.11.26 7 5 179 Korea Seoul Moram Clinic Jiwon,Park KHR 33 M 1w,24w 2013.06.12 1 1 2103.11.26 8 8 180 Korea Seoul Moram Clinic Jiwon,Park YSO 28 M 1w,24w 2013.06.13 2 2 2013.11.27 7 6 181 Korea Seoul Moram Clinic Jiwon,Park OJH 27 M 1w,24w 2013.06.14 3 3 2013.12.02 9 7 182 Korea Seoul Moram Clinic Jiwon,Park BKT 48 M 1w,24w 2013.06.14 3 3 2013.12.02 9 8 183 Korea Seoul Moram Clinic Jiwon,Park KJH 42 M 1w,24w 2013.06.14 3 3 2013.12.02 9 5 184 Korea Seoul Moram Clinic Jiwon,Park LYJ 38 M 1w,24w 2013.06.15 3 3 2013.12.10 7 7 185 Korea Seoul Moram Clinic Jiwon,Park UKS 33 M 1w,24w 2013.06.15 1 2 2013.12.10 9 8 186 Korea Seoul Moram Clinic Jiwon,Park MHJ 48 M 1w,24w 2013.06.15 3 3 2013.12.18 7 6 187 Korea Seoul Moram Clinic Jiwon,Park SCR 40 M 1w,24w 2013.06.15 2 2 2013.12.18 8 7 188 Korea Seoul Moram Clinic Jiwon,Park LSE 41 M 1w,24w 2013.06.15 4 4 2013.12.19 8 8 189 Korea Seoul Moram Clinic Jiwon,Park CYJ 49 M 1w,24w 2013.06.15 4 4 2013.12.19 9 6 190 Korea Seoul Moram Clinic Jiwon,Park KMJ 31 M 1w,24w 2013.06.18 4 4 2013.12.19 6 8
  • 63. 63 “Winner Of Nano Technology” Total Hair Loss Solution Appendix | P. Appendix ■ Trial Patients Profile – Seoul Tatoa Clinic Nationality Hospital Name Dr.Name Patient Name Age Sex Interval (Weeks) F/U Data Point (S) Point (O) F/U Date Point (S) Point (O) 191 Korea Seoul Tatoa Clinic Sukmoon,Kang RHJ 52 F 1w,24w 2013.05.15 2 4 2013.10.30 8 8 192 Korea Seoul Tatoa Clinic Sukmoon,Kang LYJ 44 M 1w,24w 2013.05.15 2 2 2013.10.30 9 7 193 Korea Seoul Tatoa Clinic Sukmoon,Kang LJH 27 M 1w,24w 2013.05.16 4 4 2013.10.30 9 9 194 Korea Seoul Tatoa Clinic Sukmoon,Kang ACH 39 F 1w,24w 2013.05.20 4 4 2013.10.30 9 8 195 Korea Seoul Tatoa Clinic Sukmoon,Kang LJY 34 M 1w,24w 2013.05.20 4 4 2013.10.31 9 6 196 Korea Seoul Tatoa Clinic Sukmoon,Kang KSH 41 M 1w,24w 2013.05.20 7 7 2013.10.31 8 9 197 Korea Seoul Tatoa Clinic Sukmoon,Kang LMJ 42 M 1w,24w 2013.05.22 5 4 2013.11.04 7 8 198 Korea Seoul Tatoa Clinic Sukmoon,Kang LBH 49 F 1w,24w 2013.05.22 3 2 2013.11.04 8 9 199 Korea Seoul Tatoa Clinic Sukmoon,Kang KMJ 34 M 1w,24w 2013.05.22 7 5 2013.11.04 9 9 200 Korea Seoul Tatoa Clinic Sukmoon,Kang LHL 40 M 1w,24w 2013.05.22 5 5 2013.11.11 8 7 201 Korea Seoul Tatoa Clinic Sukmoon,Kang NKR 44 M 1w,24w 2013.05.23 7 7 2013.11.11 9 10
  • 64. 64 “Winner Of Nano Technology” Total Hair Loss Solution Appendix | P. Appendix
  • 65. 65 “Winner Of Nano Technology” Total Hair Loss Solution Appendix | P. Appendix
  • 66. 66 “Winner Of Nano Technology” Total Hair Loss Solution Appendix | P. Appendix
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  • 68. 68 “Winner Of Nano Technology” Total Hair Loss Solution Appendix | P. Appendix
  • 69. 69 “Winner Of Nano Technology” Total Hair Loss Solution Appendix | P. Appendix
  • 70. 70 “Winner Of Nano Technology” Total Hair Loss Solution Appendix | P. Appendix
  • 71. 71 “Winner Of Nano Technology” Total Hair Loss Solution Appendix | P. Appendix
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  • 75. 75 “Winner Of Nano Technology” Total Hair Loss Solution Appendix | P. Appendix Before (0 week) 0.030mm (0week) 93 hair (24week) 0.104mm (24week) 123 hair Change of Hair Thickness Change of Hair Quantity After Test Center : Bundang Seoul National University Hospital, Kyungbuk National University KFDA, 40 Participants Test Completed ■ Clinical Phototrichogram Result
  • 76. 76 “Winner Of Nano Technology” Total Hair Loss Solution Appendix | P. Appendix (0week) 87 hair (24week) 101 hair (0week) 0.035mm (24week) 0.095mm Before After ■ Clinical Phototrichogram Result Change of Hair Thickness Change of Hair Quantity Test Center : Bundang Seoul National University Hospital, Kyungbuk National University KFDA, 40 Participants Test Completed
  • 77. 77 “Winner Of Nano Technology” Total Hair Loss Solution Appendix | P. Appendix (12week) 0.047mm (0week) 0.030mm (0week) 82 hair (24week) 105 hair Before After ■ Clinical Phototrichogram Result Change of Hair Thickness Change of Hair Quantity Test Center : Bundang Seoul National University Hospital, Kyungbuk National University KFDA, 40 Participants Test Completed
  • 78. 78 “Winner Of Nano Technology” Total Hair Loss Solution Appendix | P. Appendix (12week) 0.075mm (0week) 0.060mm (0week) 103 hair (24week) 119 hair Before After ■ Clinical Phototrichogram Result Change of Hair Thickness Change of Hair Quantity Test Center : Bundang Seoul National University Hospital, Kyungbuk National University KFDA, 40 Participants Test Completed
  • 79. 79 “Winner Of Nano Technology” Total Hair Loss Solution Appendix | P. Appendix (12week) 0.085mm (0week) 0.077mm (0week) 92 hair (24week) 120 hair Before After ■ Clinical Phototrichogram Result Change of Hair Thickness Change of Hair Quantity Test Center : Bundang Seoul National University Hospital, Kyungbuk National University KFDA, 40 Participants Test Completed
  • 80. Total Hair Loss Solution WONTECH Co., Ltd. T. +82-70-7805-8011, F. +82-70-7882-8658, E. seancho@wtlaser.com, sales@wtlaser.com Address: A-601, Pangyo-ro 242, Bundang-gu, Seongnam-si, Gyeonggi-do, S.Korea More information at www.wtlaser.com