TataKelola dan KamSiber Kecerdasan Buatan v022.pdf
Short case...Subependymal primary CNS lymphoma
1. Short case publication... version 2.3 | Edited by professor Yasser Metwally | October 2008
Short case
Edited by
Professor Yasser Metwally
Professor of neurology
Ain Shams university school of medicine
Cairo, Egypt
Visit my web site at:
http://yassermetwally.com
A 30 years old male patient presented clinically with manifestations of increased intracranial pressure, bilateral
papilledema, lower cranial nerve palsy, personality changes and hypothalamic manifestations
DIAGNOSIS: PRIMARY SUBEPENDYMAL CNS LYMPHOMA
2. Figure 1. Postcontrast CT scan study showing a densely enhanced periventricular lesions. The lesions are seen
completely surrounding the 4th, lateral and third ventricles with some perilesional edema lucencies. The lesions have
a minimal mass effect and do not appear to be compressing the ventricular system or inducing obstructive
hydrocephalus. The periventricular lesions are ensheathing the ventricular system and appear to radiate from it
centrifugally outwards forming butterfly lesions around the 4th ventricle and the frontal horns of the lateral
ventricles.
Figure 2. Postcontrast CT scan study showing a densely enhanced periventricular lesions. The lesions are seen
completely surrounding the lateral and the third ventricles with some perilesional edema lucencies. The lesions
have a minimal mass effect and do not appear to be compressing the ventricular system or inducing obstructive
hydrocephalus. The periventricular lesions are ensheathing the ventricular system and appear to radiate from
it centrifugally outwards forming butterfly lesions the frontal horns of the lateral ventricles.
3. Figure 3. A, postcontrast CT scan study, B, and C are pre and postcontrast MRI T1 studies. Notice the
densely enhanced butterfly lesions that completely encircled the 4th ventricle.
Figure 4. Postcontrast MRI T1 images. Notice the periventricular lymphomatous sheath that completely encircled
the ventricular system and appear to radiate from it centrifugally outwards forming butterfly lesions around the
4th ventricle. The periventricular lymphomatous sheath is densely enhanced and do not seem to encroach upon the
ventricular system or induce significant compression on its borders. The ventricular system, however, are mildly
dilated.
4. Figure 5. The periventricular disease completely disappeared after steroid therapy which is typical for
Primary CNS lymphoma.
Figure 6. The periventricular disease completely disappeared after steroid therapy which is typical for Primary
CNS lymphoma.
5. The patient was subjected to stereotactic brain biopsy that revealed a primary CNS lymphoma. Staging did
not reveal extraneural dissemination of the disease. The patient was referred to the oncology department for
further management
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References
1. Metwally, MYM: Textbook of neurimaging, A CD-ROM publication, (Metwally, MYM editor) WEB-CD agency
for electronic publishing, version 9.4a October 2008