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Dr. Zahoor Ahmad
                     PGR,
        Paediatric surgery,
           SZMC/H, RYK,
                  Pakistan
   Spinal nerves attach to
Spinal Nerves       the spinal cord via roots
                   Dorsal root
                     Has only sensory neurons
                     Attached to cord via rootlets
                     Dorsal root ganglion
                      ○ Bulge formed by cell bodies
                        of unipolar sensory neurons
                   Ventral root
                     Has only motor neurons
                     No ganglion - all cell bodies
                      of motor neurons found in
                      gray matter of spinal cord




                                                      12-2
Spinal Nerves
   31 pair
     each contains thousands of nerve fibers
     All are mixed nerves have both sensory and motor
      neurons)
   Connect to the spinal cord
   Named for point of issue from the spinal cord
     8 pairs of cervical nerves (C1-C8)
     12 pairs of thoracic nerves (T1-T12)
     5 pairs of lumbar nerves (L1-L5)
     5 pairs of sacral nerves (S1-S5)
     1 pair of coccygeal nerves (Co1)

                                                         12-3
Formation of Rami
 Rami are lateral branches of a
  spinal nerve
 Rami contain both sensory
  and motor neurons
 Two major groups
   Dorsal ramus
     ○ Neurons innervate the
       dorsal regions of the body
   Ventral ramus
     ○ Larger
     ○ Neurons innervate the
       ventral regions of the
       body
     ○ Braid together to form
       plexuses (plexi)

                                    12-4
Dermatomal Map
   Spinal nerves indicated by capital letter and number
   Dermatomal map: skin area supplied with sensory
    innervation by spinal nerves




                                                           12-5
Introduction to Nerve Plexuses

    Nerve plexus
      A network of ventral rami
    Ventral rami (except T2-T12)
      Branch and join with one another
      Form nerve plexuses
       ○ In cervical, brachial, lumbar, and sacral regions
       ○ No plexus formed in thoracic region of s.c.




                                                             12-6
   Dorsal Ramus
Branches of        Neurons within muscles of trunk and back
                 Ventral Ramus (VR)
Spinal             Braid together to form plexuses
                    ○ Cervical plexus - VR of C1-C4
Nerves              ○ Brachial plexus - VR of C5-T1
                    ○ Lumbar plexus - VR of of L1-L4
                    ○ Sacral plexus - VR of L4-S4
                    ○ Coccygeal plexus -VR of S4 and S5
                 Communicating Rami: communicate
                  with sympathetic chain of ganglia
                   Covered in ANS unit




                                                          12-7
Brachial Plexus
                 Formed by ventral rami of
                  spinal nerves C5-T1
                 Five ventral rami form
                   three trunks that separate into
                   six divisions that then form
                   cords that give rise to nerves
                 Major nerves
                   Axillary
                   Radial
                   Musculocutaneous
                   Ulnar
                   Median



                                                      12-8
Brachial Plexus: Axillary Nerve
                      Motor neurons stimulate
                        Deltoid, teres minor
                         ○ Abducts arm- deltoid
                         ○ Laterally rotate arm-teres
                           minor
                      Sensory neurons
                        Skin: inferior lateral
                         shoulder




                                                   12-9
Brachial Plexus: Radial Nerve
                 Motor components stimulate
                   Posterior muscles of arm, forearm, and
                    hand
                    ○ Triceps, supinator, brachioradialis,
                      extensors
                    ○ Cause extension movements at elbow
                      and wrist, thumb movements
                 Sensory components
                   Skin on posterior surface of arm and
                    forearm, hand




                                                             12-10
Brachial Plexus:
Musculocutaneous Nerve
                      Motor components stimulate
                          Flexors in anterior upper arm:
                           (biceps brachii, brachialis)
                           ○ Cause flexion movements at
                             shoulder and elbow
                      Sensory: Skin along lateral
                       surface of forearm




                                                     12-11
Brachial Plexus: Ulnar Nerve
                    Motor components
                     stimulate
                      Flexor muscles in anterior
                       forearm (FCU, FDP, most
                       intrinsic muscles of hand)
                      Results in wrist and finger
                       flexion
                    Sensory: Skin on medial
                     part of hand




                                                 12-12
Brachial Plexus: Median Nerve
                     Motor components
                      stimulate
                       All but one of the flexors of the
                        wrist and fingers, and thenar
                        muscles at base of thumb
                        (Palmaris longus, FCR, FDS,
                        FPL, pronator)
                       Causes flexion of the wrist
                        and fingers and thumb
                     Sensory components
                       Stimulate skin on lateral part
                        of hand




                                                      12-13
Dermatomes of the Posterior Arm
Dermatomes of the Anterior Arm
Etiology
   traffic accidents
   birth injuries
   humerus luxations
   brachial plexus neuritis
   stab and bullet wounds
   tumors (especially lung cancer)
   cervical rib, fibrous band from C7
    (neurogenic thoracic outlet syndrome)
Principles of Localization
   Certain sites are prone to nerve
    entrapments/injuries
     Nerve opposing bone
     ○ Ulnar nerve at the elbow
     Closed spaces
     ○ Carpal tunnel
     Adjacent structures
     ○ Median nerve at the elbow, adjacent to
       the brachial artery
Principles of localization (cont.)
 Order in which branches arise
 Movements at specific joints
     Single nerve
     ○ Elbow extension
        Radial
     Multiple nerves
     ○ Elbow flexion
        Musculocutaneous
        Radial
Brachial Plexus Injuries
   Upper Lesions of the Brachial
    Plexus (Erb’s Palsy): resulting from
    excessive displacement of the head to
    opposite side and depression of shoulder
    on the same side.
 Thiscauses excessive traction or
 even tearing of C5 and 6 roots of
 the plexus. It occurs in infants
 during a difficult delivery or in
 adults after a blow to or fall on
 shoulder.
Effects:
Motor: paralysis of
   the supraspinatus,
   infraspinatus,
   subclavius,
   biceps brachii,
   part of brachialis,
   coracobrachialis;
   deltoid
   teres minor.
Sensroy: sensory loss on the lateral side
    of the arm.
 Deformity:
 waiter   tip postion
c. limb will hang by the side,
d. medially rotated by sternocostal part
   of the pectoralis major;
e. pronated forearm (biceps paralysis)
Erb-Duchenne palsy (waiter's tip)
Lower Lesions of the Brachial Plexus
(Klumpke Palsy)
 traction injuries by excessive abduction of
  the arm
 i.e. occurs if person falling from a height
  clutching at an object to save himself or
  herself.
 Can be caused by cervical rib.
 T1 is usually torn (ulnar and median
  nerves)
Motor Effects: paralysis of all the
  small muscles of the hand.
Sensory effects: loss of sensation
  along the medial side of the arm.
deformity: claw hand caused by
  hyperextension of the
  metacarpophalangeal joints and
  flexion of the interphalangeal
  joints.
Axillary Nerve injury
Causes:
crutch pressing upward into the
armpit,
Downward shoulder dislocations
fractures of the surgical neck of the
humerus.
Motor       effects:
 Deltoidparalysis
 teres minor paralysis.
Sensory effects:
 lossof sensation at lower ½ of
 deltoid
Deformity:
 Wasting   of deltoid
Radial Nerve injury
Injury in axilla :
crutch pressing up into armpit
drunkard falling asleep with
 one arm over the back of a
 chair.
fractures of proximal humerus.
 Motor  effects:paralysis of
 triceps
 Anconeus
 extensors of the wrist
 Extensors of fingers.
 Brachioradialis
 supinator muscle
 Deformity: Wrist and finger
  drop
Sensory       effects :
 small area of sansation
  loss at arm and forearm
 sensory loss over lateral
  part of the dorsum of the
  hand (lat. 3.5 fingers
  without distal phalynges)
Injuries at Spiral Groove
 Caused  by fracture shaft of humerus.
 Motor effects: paralysis of
 extensors of the wrist
 Extensors of fingers
 Deformity:
 Wrist  and finger drop
 Sensory effects:
 anesthesia is present over the
  dorsal surface of the hand (lat.
  3.5 fingers)
Median Nerve
injury
  Motor effects: paralysis of
 pronator muscles
 long flexor muscles of the wrist
  and fingers,
 Exception:
e. flexor carpi ulnaris
f. medial half flexor digitorum profundus.
Deformity:
apelike hand
3.thenar muscles wasted
4.thumb is laterally rotated and
  adducted.
5.index and to a lesser extent
  the middle fingers tend to
  remain straight on making
6.Weakening of lat. 2 fingers
Sensory:
 Sensory  loss on the lat. 3.5
  fingers on palmar side
 Sensory loss over distal
  phalynges of lat. 4 fingers on
  dorsal surface
Ulnar nerve injury
 Motor   effects: paralysis of
 flexor carpi ulnaris
 medial half of the flexor digitorum
  profundus
 All interossei
 3-4 lumbricals
 loss of abduction and adduction of
  fingers
 Wasting of hypothenar
Deformity:
 partial
        claw hand
Sensory effects :
 Sensory loss over 1.5 fingers on
  both surfaces
CARPAL TUNNEL
  TUNNEL FORMED BETWEEN THE CONCAVITY OF THE
   CARPAL BONES AND A LIGAMENT THAT COVERS
   THIS( FLEXOR RETINACULAM)
 TENDONS OF THE FLEXORS PASS THROUGH
 MEDIAN NERVE ALSO PASSES THROUGH
 CROWDED TUNNEL
CARPAL TUNNEL SYNDROME
-  CAUSED DUE TO COMPRESSION OF THE NERVE IN THE
   TUNNEL
-  CAUSES-
-  1. SWELLING OF THE TEDONS( OVERUSE)
-  2. PREGNANCY( EDEMA)
-  3. ARTHRITIS
SYMPTOMS- TINGLING OR NUMBNESS-LATERAL PART OF HAND,
   WEAKNESS IN THUMB MOVEMENT
TREATMENT- REST, SPLINTING,ANTI-INFLAMMATORY DRUGS,
   SURGERY
Diagnosis
 Relies mainly on clinical examination
 No specific lab. Studies
 CT myelography
 MRI
 Nerve conduction studies
Treatment
  Most injuries recover without any Rx
 Rx is done in very highly specialized
   centers
 Surgical options
d. nerve transfers
e. nerve grafting
f. muscle transfers
g. free muscle transfers
h. neurolysis of scar around the brachial
   plexus in incomplete lesions.
Advances in nerve injury Rx
 Carlstedt obtained promising initial
  results with the repair of preganglionic
  lesions by replanting nerve rootlets
  directly into the spinal cord.
 This is a dramatic advance because
  preganglionic lesions were previously
  thought to be irreparable
End-to-side radial sensory to
median nerve transfer has
been reported to improve
sensation and to relieve pain
in C5 and C6 nerve root
avulsion
Thank
 you

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Brachial plexus injuries

  • 1. Dr. Zahoor Ahmad PGR, Paediatric surgery, SZMC/H, RYK, Pakistan
  • 2. Spinal nerves attach to Spinal Nerves the spinal cord via roots  Dorsal root  Has only sensory neurons  Attached to cord via rootlets  Dorsal root ganglion ○ Bulge formed by cell bodies of unipolar sensory neurons  Ventral root  Has only motor neurons  No ganglion - all cell bodies of motor neurons found in gray matter of spinal cord 12-2
  • 3. Spinal Nerves  31 pair  each contains thousands of nerve fibers  All are mixed nerves have both sensory and motor neurons)  Connect to the spinal cord  Named for point of issue from the spinal cord  8 pairs of cervical nerves (C1-C8)  12 pairs of thoracic nerves (T1-T12)  5 pairs of lumbar nerves (L1-L5)  5 pairs of sacral nerves (S1-S5)  1 pair of coccygeal nerves (Co1) 12-3
  • 4. Formation of Rami  Rami are lateral branches of a spinal nerve  Rami contain both sensory and motor neurons  Two major groups  Dorsal ramus ○ Neurons innervate the dorsal regions of the body  Ventral ramus ○ Larger ○ Neurons innervate the ventral regions of the body ○ Braid together to form plexuses (plexi) 12-4
  • 5. Dermatomal Map  Spinal nerves indicated by capital letter and number  Dermatomal map: skin area supplied with sensory innervation by spinal nerves 12-5
  • 6. Introduction to Nerve Plexuses  Nerve plexus  A network of ventral rami  Ventral rami (except T2-T12)  Branch and join with one another  Form nerve plexuses ○ In cervical, brachial, lumbar, and sacral regions ○ No plexus formed in thoracic region of s.c. 12-6
  • 7. Dorsal Ramus Branches of  Neurons within muscles of trunk and back  Ventral Ramus (VR) Spinal  Braid together to form plexuses ○ Cervical plexus - VR of C1-C4 Nerves ○ Brachial plexus - VR of C5-T1 ○ Lumbar plexus - VR of of L1-L4 ○ Sacral plexus - VR of L4-S4 ○ Coccygeal plexus -VR of S4 and S5  Communicating Rami: communicate with sympathetic chain of ganglia  Covered in ANS unit 12-7
  • 8. Brachial Plexus  Formed by ventral rami of spinal nerves C5-T1  Five ventral rami form  three trunks that separate into  six divisions that then form  cords that give rise to nerves  Major nerves  Axillary  Radial  Musculocutaneous  Ulnar  Median 12-8
  • 9. Brachial Plexus: Axillary Nerve  Motor neurons stimulate  Deltoid, teres minor ○ Abducts arm- deltoid ○ Laterally rotate arm-teres minor  Sensory neurons  Skin: inferior lateral shoulder 12-9
  • 10. Brachial Plexus: Radial Nerve  Motor components stimulate  Posterior muscles of arm, forearm, and hand ○ Triceps, supinator, brachioradialis, extensors ○ Cause extension movements at elbow and wrist, thumb movements  Sensory components  Skin on posterior surface of arm and forearm, hand 12-10
  • 11. Brachial Plexus: Musculocutaneous Nerve  Motor components stimulate  Flexors in anterior upper arm: (biceps brachii, brachialis) ○ Cause flexion movements at shoulder and elbow  Sensory: Skin along lateral surface of forearm 12-11
  • 12. Brachial Plexus: Ulnar Nerve  Motor components stimulate  Flexor muscles in anterior forearm (FCU, FDP, most intrinsic muscles of hand)  Results in wrist and finger flexion  Sensory: Skin on medial part of hand 12-12
  • 13. Brachial Plexus: Median Nerve  Motor components stimulate  All but one of the flexors of the wrist and fingers, and thenar muscles at base of thumb (Palmaris longus, FCR, FDS, FPL, pronator)  Causes flexion of the wrist and fingers and thumb  Sensory components  Stimulate skin on lateral part of hand 12-13
  • 14. Dermatomes of the Posterior Arm
  • 15. Dermatomes of the Anterior Arm
  • 16. Etiology  traffic accidents  birth injuries  humerus luxations  brachial plexus neuritis  stab and bullet wounds  tumors (especially lung cancer)  cervical rib, fibrous band from C7 (neurogenic thoracic outlet syndrome)
  • 17. Principles of Localization  Certain sites are prone to nerve entrapments/injuries  Nerve opposing bone ○ Ulnar nerve at the elbow  Closed spaces ○ Carpal tunnel  Adjacent structures ○ Median nerve at the elbow, adjacent to the brachial artery
  • 18. Principles of localization (cont.)  Order in which branches arise  Movements at specific joints  Single nerve ○ Elbow extension  Radial  Multiple nerves ○ Elbow flexion  Musculocutaneous  Radial
  • 19. Brachial Plexus Injuries  Upper Lesions of the Brachial Plexus (Erb’s Palsy): resulting from excessive displacement of the head to opposite side and depression of shoulder on the same side.
  • 20.  Thiscauses excessive traction or even tearing of C5 and 6 roots of the plexus. It occurs in infants during a difficult delivery or in adults after a blow to or fall on shoulder.
  • 21. Effects: Motor: paralysis of  the supraspinatus,  infraspinatus,  subclavius,  biceps brachii,  part of brachialis,  coracobrachialis;  deltoid  teres minor. Sensroy: sensory loss on the lateral side of the arm.
  • 22.  Deformity:  waiter tip postion c. limb will hang by the side, d. medially rotated by sternocostal part of the pectoralis major; e. pronated forearm (biceps paralysis)
  • 24. Lower Lesions of the Brachial Plexus (Klumpke Palsy)  traction injuries by excessive abduction of the arm  i.e. occurs if person falling from a height clutching at an object to save himself or herself.  Can be caused by cervical rib.  T1 is usually torn (ulnar and median nerves)
  • 25. Motor Effects: paralysis of all the small muscles of the hand. Sensory effects: loss of sensation along the medial side of the arm. deformity: claw hand caused by hyperextension of the metacarpophalangeal joints and flexion of the interphalangeal joints.
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  • 27. Axillary Nerve injury Causes: crutch pressing upward into the armpit, Downward shoulder dislocations fractures of the surgical neck of the humerus.
  • 28. Motor effects:  Deltoidparalysis  teres minor paralysis. Sensory effects:  lossof sensation at lower ½ of deltoid Deformity:  Wasting of deltoid
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  • 30. Radial Nerve injury Injury in axilla : crutch pressing up into armpit drunkard falling asleep with one arm over the back of a chair. fractures of proximal humerus.
  • 31.  Motor effects:paralysis of  triceps  Anconeus  extensors of the wrist  Extensors of fingers.  Brachioradialis  supinator muscle  Deformity: Wrist and finger drop
  • 32. Sensory effects :  small area of sansation loss at arm and forearm  sensory loss over lateral part of the dorsum of the hand (lat. 3.5 fingers without distal phalynges)
  • 33. Injuries at Spiral Groove  Caused by fracture shaft of humerus.  Motor effects: paralysis of  extensors of the wrist  Extensors of fingers
  • 34.  Deformity:  Wrist and finger drop  Sensory effects:  anesthesia is present over the dorsal surface of the hand (lat. 3.5 fingers)
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  • 37. Median Nerve injury  Motor effects: paralysis of  pronator muscles  long flexor muscles of the wrist and fingers,  Exception: e. flexor carpi ulnaris f. medial half flexor digitorum profundus.
  • 38. Deformity: apelike hand 3.thenar muscles wasted 4.thumb is laterally rotated and adducted. 5.index and to a lesser extent the middle fingers tend to remain straight on making 6.Weakening of lat. 2 fingers
  • 39. Sensory:  Sensory loss on the lat. 3.5 fingers on palmar side  Sensory loss over distal phalynges of lat. 4 fingers on dorsal surface
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  • 43. Ulnar nerve injury  Motor effects: paralysis of  flexor carpi ulnaris  medial half of the flexor digitorum profundus  All interossei  3-4 lumbricals  loss of abduction and adduction of fingers  Wasting of hypothenar
  • 44. Deformity:  partial claw hand Sensory effects :  Sensory loss over 1.5 fingers on both surfaces
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  • 48. CARPAL TUNNEL  TUNNEL FORMED BETWEEN THE CONCAVITY OF THE CARPAL BONES AND A LIGAMENT THAT COVERS THIS( FLEXOR RETINACULAM)  TENDONS OF THE FLEXORS PASS THROUGH  MEDIAN NERVE ALSO PASSES THROUGH  CROWDED TUNNEL CARPAL TUNNEL SYNDROME - CAUSED DUE TO COMPRESSION OF THE NERVE IN THE TUNNEL - CAUSES- - 1. SWELLING OF THE TEDONS( OVERUSE) - 2. PREGNANCY( EDEMA) - 3. ARTHRITIS SYMPTOMS- TINGLING OR NUMBNESS-LATERAL PART OF HAND, WEAKNESS IN THUMB MOVEMENT TREATMENT- REST, SPLINTING,ANTI-INFLAMMATORY DRUGS, SURGERY
  • 49. Diagnosis  Relies mainly on clinical examination  No specific lab. Studies  CT myelography  MRI  Nerve conduction studies
  • 50. Treatment  Most injuries recover without any Rx  Rx is done in very highly specialized centers  Surgical options d. nerve transfers e. nerve grafting f. muscle transfers g. free muscle transfers h. neurolysis of scar around the brachial plexus in incomplete lesions.
  • 51. Advances in nerve injury Rx  Carlstedt obtained promising initial results with the repair of preganglionic lesions by replanting nerve rootlets directly into the spinal cord.  This is a dramatic advance because preganglionic lesions were previously thought to be irreparable
  • 52. End-to-side radial sensory to median nerve transfer has been reported to improve sensation and to relieve pain in C5 and C6 nerve root avulsion
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