Affordability Through Sustainability

Changing the Design Paradigm. Affordability and Access through sustainability. Bala Manian, PhD. ReaMetrix Inc. San Carlos, CA

What is the context of my talk? ,[object Object],[object Object],[object Object],[object Object],[object Object]

Why & how do we need to look at this differently? ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Diagnostics – A case study ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Example - CD4/CD8 Reagents ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Measurement of Absolute CD4+ and CD8+ T cell counts using Tri T-STAT 1. Identification of CD3+ T-Cells 2. Enumeration of volume metering beads 3. CD4+ & CD8+ T-Cell counts derived from the CD3+ T-Cell population  CD8 + T-Cells  CD4+ T-Cells

Correlation of Tri T STAT with accepted standards

Tri T-STAT Proven Reproducibility Cell Type Level Mean SD CV (%) CD4+CD3+ T cells High 936 18 1.9 Medium 461 19 4.1 Low 168 7 4.3 CD8+CD3+ T cells High 721 14 2.0 Medium 486 14 2.8 Low 243 11 4.5

How do we define resource poor setting? ,[object Object],[object Object],[object Object],[object Object]

Does India represent Resource poor setting?

What is the existing paradigm? ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

What is wrong in this picture? ,[object Object],[object Object],[object Object],[object Object],[object Object]

How to frame the big picture? ,[object Object],[object Object],[object Object],[object Object],[object Object]

Anatomy of the Cost of Goods Sold (COGS) ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

How the costs are influenced? ,[object Object],[object Object],[object Object],[object Object]

Different priorities in different environments ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

How to change the paradigm? ,[object Object],[object Object],[object Object],[object Object],[object Object]

Dry Reagents ,[object Object],[object Object],[object Object],[object Object],[object Object]

Sample collection & centralized processing ,[object Object],[object Object],[object Object],[object Object],[object Object]

Post fixation stability of blood sample

Unintended benefits derived from dry reagents ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

What lessons are to be learned? ,[object Object],[object Object],[object Object],[object Object],[object Object]

Thinking differently about Healthcare Delivery ( Work being carried out by HAP (http://www.hapindia.org/))

Saantwanam A health screening project Kerala (India) ,[object Object],[object Object],[object Object],[object Object]

The Investment ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Item Cost [Rs]

[object Object],[object Object],[object Object],[object Object],[object Object],10 glucose estimations 250 15 blood pressure 150 10 BMI 50 Average income/day 450 Total per month 1250 Net income anticipated - over Rs 5000 per month Over 150 care givers servicing 200K screens/ year 20% earning over Rs. 10,000 per month. Expense Income

What questions that arise from this observation? ,[object Object],[object Object],[object Object],[object Object]

In summary… ,[object Object],[object Object],[object Object],[object Object],[object Object]

Affordability Through Sustainability

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Affordability Through Sustainability