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Name: Zach

                                                                                          Date: 2/8/2013



                                                 Analysis



                                                 Table 1

                        Anti-A Serum         Anti-B Serum         Anti-Rh Serum           Blood Type
Slide 1- Mrs. Smith     Agglutilation       No Agglutilation       Agglutilation              A
 Slide 2- Mr. Jones    No agglutilation      Agglutilation        No agglutilation             B
Slide 3- Mr. Green      Agglutilation        Agglutilation         Agglutilation              AB
Slide 4- Ms. Brown     No agglutilation     No agglutilation      No agglutilation            O




1) Choose one of the following patients:
   a) Mr. Smith, Mr. Jones, Mr. Green, Ms. Brown= Mr. Green
   b) Using the information shown in Figure 1 on Blood type and the data recorded in Table 1, What
       agglutinogens are present on the patient’s RBC’s? A and B
   c) What ABO agglutinin(s) is/are found in the patient’s Plasma? Neither anti-A or anti-B
   d) What is the patient’s blood type? AB
   e) If this patient needed a transfusion, what blood type(s) could this patient safely receive? O, A, B,
       AB
   f) What blood type(s) could safely receive this patient’s blood? AB
2) Below is the information representing the blood type analysis of a new patient (patient X). From the
   information obtained, fill out the medical technologist report.
   A: Agglutination               Medical technologist’s report
   B: No Agglutination                 ABO Type: Anti-B
   Rh: Agglutination                   Rh Type: Rh+




3) Compare and Contrast agglutinogens and agglutinins. In the diagram show at least 2 similarities and
   2 differences.
                  Agglutinogens                                        Agglutinins
Differences                          Similarities                     Differences
       On red cell membranes,         Can’t mix with eachother, or           Describes the antibodies
    characterize the different ABO    else fatal event known as           dissolved in plasma that react
       blood groups. These are        transfusion reaction may occur.       with specific blood group
               antigens.              Found in blood. Substances of         antigens or agglutinogens.
                                      protein.                                These are antibodies.


4) Pretend you went with your class on a medical career field trip to a local hospital. One of the stops
   on the visit was to the hospital’s blood lab. The medical technologist at this stop gave a
   demonstration of how blood types are determined. Your job is to write a paragraph for the school
   newspaper on the visit to the blood lab, summarizing what you’ve learned about how ABO/Rh blood
   groups are determined. Write a paragraph and include the title.
                               Medical Students Visit Local Hospital
   A group of our school’s medical students recently visited a local hospital with hopes of learning
   more about their near future in the medical field. Upon arriving, the Nurses quickly started the tour
   which first included the blood lab. Students recall that in the blood lab they learned about how
   ABO/Rh blood groups are determined. To determine ABO blood groups, it depends on the antigens
   present on the red blood cell membranes. Type A blood has Antigen-A antigensd on the RBC’s, type
   B blood has Antigen-B antigens on the RBC’s, type AB has both Antigen-A and Antigen-B on the
   RBC’s, and type O has neither Antigen-A or Antigen-B antigens present on the RBC’s. So depending
   on the antigens present on the RBC’s a scientisit can determine a person’s ABO blood group. In
   order to determine a person’s RH blood group there can be positive or negative RH blood. In Rh-
   positive blood the Rh antigen is present on its RBC’s, and Rh-negative blood has red blood cells that
   do not have an RH antigen on them. Students reported their findings, and are informed a lot about
   the Rh and ABO blood groups after their visit last week.

5) List at least 3 situations where blood typing could be used.
   a) Blood transfusions
   b) Medico-legal situations when determiningdisputed paternity
   c) To avoid transfusion fatalities (different blood groups mixing)
6) Define Erythroblastosis Fetalis. Condition of a fetus or infant caused by the mother’s Rh antibodies
   reacting with the baby’s Rh-positive red blood cells, characterized by massive agglutination of the
   blood and resulting in life-threatening circulatory problems for the infant.
   a) Describe the sequence of events that lead to this condition.
        First, blood doesn’t normally contain anti-Rh antibodies, however they can appear if the Rh-
        negative person, provided Rh-positive RBC’s and combined at some point in the bloodstream.
        The person’s body starts making anti-Rh antibodies, and can happen during pregnancy. If the
        baby inherits the Rh-positive trait from the father, the Rh factor on the RBCs may stimulate the
        mother to form anti-Rh antibodies. If she later carries an Rh-positive fetus, the fetus may
        develop this disease.
b) What might be some benefits if the medical profession developed a shot or vaccination that
      could desensitize an Rh+ situation? The benefits would be a decrease of the risk to the Rh+
      babies of pregnancies. You could then bring Rh+ blood to Rh- individual in natural life.
7) You are a type A eryhthorocyte placing an ad in the personals and you are seeking a compatible
   mate for a long lasting transfusion. Create an ad to be submitted to the newspaper.

    SEARCHING FOR A BLOOD MATE – Must be blood type A or O to receive! Call me at 1-800-
    INEEDBLOOD.

8) Another important diagnostic tool used by medical technologist is determining a patient’s blood cell
    count, for both red blood cells and white blood cells. When this procedure is performed, one
    technique used is to take multiple samples and calculate the average. This method of multiple
    sampling is a standard procedure in scientific and medical investigations. Discuss why this method is
    important in blood typing. The multiple sampling strategy, gives a more accurate sampling. This is
    important in blood typing because it provides a more accurate blood type limiting contamination
    and human error so that way blood types are determined accurately without error or human
    contamination.
9) Each year thousands of people contract blood borne diseases. What could be done in a clinical
    blood lab to minimize the risk of obtaining or spreading a blood borne disease? Everything needs to
    be constantly sterilized, and properly labeled along with being stored at proper temperatures to
    prevent any bacteria growing in the blood.
10) In a short paragraph, identify what you think may be the next important breakthrough, milestone or
    discovery in the study of blood and blood diseases and explain why. I think the next important
    breakthough is synthetic blood that can be used for everyone, regardless of blood type. This will
    reduce the number of blood donors needed if blood can be created in a lab. It will also cause less
    difficulty in finding a blood match because the exact type needed can be made.

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Blood typing analysis

  • 1. Name: Zach Date: 2/8/2013 Analysis Table 1 Anti-A Serum Anti-B Serum Anti-Rh Serum Blood Type Slide 1- Mrs. Smith Agglutilation No Agglutilation Agglutilation A Slide 2- Mr. Jones No agglutilation Agglutilation No agglutilation B Slide 3- Mr. Green Agglutilation Agglutilation Agglutilation AB Slide 4- Ms. Brown No agglutilation No agglutilation No agglutilation O 1) Choose one of the following patients: a) Mr. Smith, Mr. Jones, Mr. Green, Ms. Brown= Mr. Green b) Using the information shown in Figure 1 on Blood type and the data recorded in Table 1, What agglutinogens are present on the patient’s RBC’s? A and B c) What ABO agglutinin(s) is/are found in the patient’s Plasma? Neither anti-A or anti-B d) What is the patient’s blood type? AB e) If this patient needed a transfusion, what blood type(s) could this patient safely receive? O, A, B, AB f) What blood type(s) could safely receive this patient’s blood? AB 2) Below is the information representing the blood type analysis of a new patient (patient X). From the information obtained, fill out the medical technologist report. A: Agglutination Medical technologist’s report B: No Agglutination  ABO Type: Anti-B Rh: Agglutination  Rh Type: Rh+ 3) Compare and Contrast agglutinogens and agglutinins. In the diagram show at least 2 similarities and 2 differences. Agglutinogens Agglutinins
  • 2. Differences Similarities Differences On red cell membranes, Can’t mix with eachother, or Describes the antibodies characterize the different ABO else fatal event known as dissolved in plasma that react blood groups. These are transfusion reaction may occur. with specific blood group antigens. Found in blood. Substances of antigens or agglutinogens. protein. These are antibodies. 4) Pretend you went with your class on a medical career field trip to a local hospital. One of the stops on the visit was to the hospital’s blood lab. The medical technologist at this stop gave a demonstration of how blood types are determined. Your job is to write a paragraph for the school newspaper on the visit to the blood lab, summarizing what you’ve learned about how ABO/Rh blood groups are determined. Write a paragraph and include the title. Medical Students Visit Local Hospital A group of our school’s medical students recently visited a local hospital with hopes of learning more about their near future in the medical field. Upon arriving, the Nurses quickly started the tour which first included the blood lab. Students recall that in the blood lab they learned about how ABO/Rh blood groups are determined. To determine ABO blood groups, it depends on the antigens present on the red blood cell membranes. Type A blood has Antigen-A antigensd on the RBC’s, type B blood has Antigen-B antigens on the RBC’s, type AB has both Antigen-A and Antigen-B on the RBC’s, and type O has neither Antigen-A or Antigen-B antigens present on the RBC’s. So depending on the antigens present on the RBC’s a scientisit can determine a person’s ABO blood group. In order to determine a person’s RH blood group there can be positive or negative RH blood. In Rh- positive blood the Rh antigen is present on its RBC’s, and Rh-negative blood has red blood cells that do not have an RH antigen on them. Students reported their findings, and are informed a lot about the Rh and ABO blood groups after their visit last week. 5) List at least 3 situations where blood typing could be used. a) Blood transfusions b) Medico-legal situations when determiningdisputed paternity c) To avoid transfusion fatalities (different blood groups mixing) 6) Define Erythroblastosis Fetalis. Condition of a fetus or infant caused by the mother’s Rh antibodies reacting with the baby’s Rh-positive red blood cells, characterized by massive agglutination of the blood and resulting in life-threatening circulatory problems for the infant. a) Describe the sequence of events that lead to this condition. First, blood doesn’t normally contain anti-Rh antibodies, however they can appear if the Rh- negative person, provided Rh-positive RBC’s and combined at some point in the bloodstream. The person’s body starts making anti-Rh antibodies, and can happen during pregnancy. If the baby inherits the Rh-positive trait from the father, the Rh factor on the RBCs may stimulate the mother to form anti-Rh antibodies. If she later carries an Rh-positive fetus, the fetus may develop this disease.
  • 3. b) What might be some benefits if the medical profession developed a shot or vaccination that could desensitize an Rh+ situation? The benefits would be a decrease of the risk to the Rh+ babies of pregnancies. You could then bring Rh+ blood to Rh- individual in natural life. 7) You are a type A eryhthorocyte placing an ad in the personals and you are seeking a compatible mate for a long lasting transfusion. Create an ad to be submitted to the newspaper. SEARCHING FOR A BLOOD MATE – Must be blood type A or O to receive! Call me at 1-800- INEEDBLOOD. 8) Another important diagnostic tool used by medical technologist is determining a patient’s blood cell count, for both red blood cells and white blood cells. When this procedure is performed, one technique used is to take multiple samples and calculate the average. This method of multiple sampling is a standard procedure in scientific and medical investigations. Discuss why this method is important in blood typing. The multiple sampling strategy, gives a more accurate sampling. This is important in blood typing because it provides a more accurate blood type limiting contamination and human error so that way blood types are determined accurately without error or human contamination. 9) Each year thousands of people contract blood borne diseases. What could be done in a clinical blood lab to minimize the risk of obtaining or spreading a blood borne disease? Everything needs to be constantly sterilized, and properly labeled along with being stored at proper temperatures to prevent any bacteria growing in the blood. 10) In a short paragraph, identify what you think may be the next important breakthrough, milestone or discovery in the study of blood and blood diseases and explain why. I think the next important breakthough is synthetic blood that can be used for everyone, regardless of blood type. This will reduce the number of blood donors needed if blood can be created in a lab. It will also cause less difficulty in finding a blood match because the exact type needed can be made.