SlideShare une entreprise Scribd logo
1  sur  10
Télécharger pour lire hors ligne
Machine Learning
Simulated Annealing
Intro
● Annealing – cooling temperature in metallargy
● An optimization algo inspired by Stastical
Mechanics
● Combination of –
1) MCMC Algo
2) Metropilos Algo
MCMC Algo
● Marcov Chain Monte Carlo
● Involves a Stochastic element (random)
● This helps computer to take random decisions
● Depends on state and transition between 2
states in MM
Metropolis Algo
● Randomly generates perturbations of current
state (approx soln)
● Accepts or rejects them based on how the
probability of state is effected
● Like a schedule of lovering temperature
Example – Minimizing a function
● F = (x1.....xn) and f>=0
● If f – represemtsenergy of a stastical
mechanical system
● We have states S=(x1....xn)
● Hence the probability of state S at temperature T
is given by
● p(S) =
Boltzmann-gibbs distribution
● If there are m states
● Limits P(S) = 1/m (is Sis at ground state)
t->0 = 0 (if otherwise)
● Hence we could stimulate the system at
temperature near 0, we get ground state
● But MCMC and Metropolis fail to generate
Minima
● Because, movement in state space is inhibited
by regions of low probability and by high energy
barriers
● Simulated Anneling overcomes this problem
● Starts at high temp and progresses to lower temp
● Annealing Schedule is given By -
●
●
● Hence as algo proceeds – inc in energy is less
likely
● And hence minima of energy could be acheived
Applications
● Molecular Dynamics
● PL docing
● Homology Modelling
Applications
● Molecular Dynamics
● PL docing
● Homology Modelling

Contenu connexe

Tendances

Randomizing quicksort algorith with example
Randomizing quicksort algorith with exampleRandomizing quicksort algorith with example
Randomizing quicksort algorith with examplemaamir farooq
 
Lecture 6 modelling-of_electrical__electronic_systems
Lecture 6 modelling-of_electrical__electronic_systemsLecture 6 modelling-of_electrical__electronic_systems
Lecture 6 modelling-of_electrical__electronic_systemsSaifullah Memon
 
Modeling of mechanical_systems
Modeling of mechanical_systemsModeling of mechanical_systems
Modeling of mechanical_systemsJulian De Marcos
 
modeling of MECHANICAL system (translational), Basic Elements Modeling-Spring...
modeling of MECHANICAL system (translational), Basic Elements Modeling-Spring...modeling of MECHANICAL system (translational), Basic Elements Modeling-Spring...
modeling of MECHANICAL system (translational), Basic Elements Modeling-Spring...Waqas Afzal
 
Transient response analysis
Transient response analysisTransient response analysis
Transient response analysisasari_dear
 
Transfer fn mech. systm
Transfer fn mech. systmTransfer fn mech. systm
Transfer fn mech. systmSyed Saeed
 
JOB PORTFOLIO_PRASHANTH_2015 [Compatibility Mode]
JOB PORTFOLIO_PRASHANTH_2015 [Compatibility Mode]JOB PORTFOLIO_PRASHANTH_2015 [Compatibility Mode]
JOB PORTFOLIO_PRASHANTH_2015 [Compatibility Mode]Prashanth Ramachandran
 
Nyquist and polar plot 118 & 117
Nyquist and polar plot 118 & 117Nyquist and polar plot 118 & 117
Nyquist and polar plot 118 & 117RishabhKashyap2
 
FINAL EXAM_PRASHANTH_2012 [Compatibility Mode]
FINAL EXAM_PRASHANTH_2012 [Compatibility Mode]FINAL EXAM_PRASHANTH_2012 [Compatibility Mode]
FINAL EXAM_PRASHANTH_2012 [Compatibility Mode]Prashanth Ramachandran
 
Mechanical system
Mechanical systemMechanical system
Mechanical systemAliAhssan
 
Lecture 2 transfer-function
Lecture 2 transfer-functionLecture 2 transfer-function
Lecture 2 transfer-functionSaifullah Memon
 

Tendances (19)

Chemical Bonding
Chemical BondingChemical Bonding
Chemical Bonding
 
Simple & Fast Fluids
Simple & Fast FluidsSimple & Fast Fluids
Simple & Fast Fluids
 
Randomizing quicksort algorith with example
Randomizing quicksort algorith with exampleRandomizing quicksort algorith with example
Randomizing quicksort algorith with example
 
Lecture 6 modelling-of_electrical__electronic_systems
Lecture 6 modelling-of_electrical__electronic_systemsLecture 6 modelling-of_electrical__electronic_systems
Lecture 6 modelling-of_electrical__electronic_systems
 
Modeling of mechanical_systems
Modeling of mechanical_systemsModeling of mechanical_systems
Modeling of mechanical_systems
 
Lecture 11 ME 176 5 Stability
Lecture 11 ME 176 5 StabilityLecture 11 ME 176 5 Stability
Lecture 11 ME 176 5 Stability
 
modeling of MECHANICAL system (translational), Basic Elements Modeling-Spring...
modeling of MECHANICAL system (translational), Basic Elements Modeling-Spring...modeling of MECHANICAL system (translational), Basic Elements Modeling-Spring...
modeling of MECHANICAL system (translational), Basic Elements Modeling-Spring...
 
Transient response analysis
Transient response analysisTransient response analysis
Transient response analysis
 
Transfer Function
Transfer FunctionTransfer Function
Transfer Function
 
Problem 1 i ph o 36
Problem 1 i ph o 36Problem 1 i ph o 36
Problem 1 i ph o 36
 
Transfer fn mech. systm
Transfer fn mech. systmTransfer fn mech. systm
Transfer fn mech. systm
 
JOB PORTFOLIO_PRASHANTH_2015 [Compatibility Mode]
JOB PORTFOLIO_PRASHANTH_2015 [Compatibility Mode]JOB PORTFOLIO_PRASHANTH_2015 [Compatibility Mode]
JOB PORTFOLIO_PRASHANTH_2015 [Compatibility Mode]
 
Nyquist and polar plot 118 & 117
Nyquist and polar plot 118 & 117Nyquist and polar plot 118 & 117
Nyquist and polar plot 118 & 117
 
FINAL EXAM_PRASHANTH_2012 [Compatibility Mode]
FINAL EXAM_PRASHANTH_2012 [Compatibility Mode]FINAL EXAM_PRASHANTH_2012 [Compatibility Mode]
FINAL EXAM_PRASHANTH_2012 [Compatibility Mode]
 
Mechanical system
Mechanical systemMechanical system
Mechanical system
 
Puc eric a3.3 infografia
Puc eric a3.3 infografiaPuc eric a3.3 infografia
Puc eric a3.3 infografia
 
Chapter 5
Chapter 5Chapter 5
Chapter 5
 
Lecture 2 transfer-function
Lecture 2 transfer-functionLecture 2 transfer-function
Lecture 2 transfer-function
 
03 dynamic.system.
03 dynamic.system.03 dynamic.system.
03 dynamic.system.
 

En vedette

I love data science
I love data scienceI love data science
I love data scienceBob Nieme
 
Daily Newsletter: 14th January, 2011
Daily Newsletter: 14th January, 2011Daily Newsletter: 14th January, 2011
Daily Newsletter: 14th January, 2011Fullerton Securities
 
Workshop #12: Research toolbox: Exploring innovation opportunities, emotion a...
Workshop #12: Research toolbox: Exploring innovation opportunities, emotion a...Workshop #12: Research toolbox: Exploring innovation opportunities, emotion a...
Workshop #12: Research toolbox: Exploring innovation opportunities, emotion a...ux singapore
 
что такое информация
что такое информациячто такое информация
что такое информацияltl65
 
The Play Ethic: lessons from play in an adverse economic climate
The Play Ethic: lessons from play in an adverse economic climateThe Play Ethic: lessons from play in an adverse economic climate
The Play Ethic: lessons from play in an adverse economic climatewww.patkane.global
 
Seth Godin's Presentation Hierarchy
Seth Godin's Presentation HierarchySeth Godin's Presentation Hierarchy
Seth Godin's Presentation HierarchyGeoff Brown
 
LeadingPlus Electronic Co.,Ltd
LeadingPlus Electronic Co.,LtdLeadingPlus Electronic Co.,Ltd
LeadingPlus Electronic Co.,LtdAllen Yao
 
The role of Community Knowledge Centres in enhancing agricultural and communi...
The role of Community Knowledge Centres in enhancing agricultural and communi...The role of Community Knowledge Centres in enhancing agricultural and communi...
The role of Community Knowledge Centres in enhancing agricultural and communi...IAALD Community
 
Tanya Kearin Resume
Tanya Kearin ResumeTanya Kearin Resume
Tanya Kearin ResumeTanya Kearin
 
W. Bruce C Bailey: The Art of Art Collecting
W. Bruce C Bailey: The Art of Art CollectingW. Bruce C Bailey: The Art of Art Collecting
W. Bruce C Bailey: The Art of Art CollectingDave Wilkin
 
CLASES DE COMPUTACION
CLASES DE COMPUTACIONCLASES DE COMPUTACION
CLASES DE COMPUTACIONebtblas
 
Cchandler portfolio feb_09_16
Cchandler portfolio feb_09_16Cchandler portfolio feb_09_16
Cchandler portfolio feb_09_16Charles Chandler
 
Daily Newsletter: 11th January, 2011
Daily Newsletter: 11th January, 2011Daily Newsletter: 11th January, 2011
Daily Newsletter: 11th January, 2011Fullerton Securities
 
Community Interactions And Sucession
Community Interactions And SucessionCommunity Interactions And Sucession
Community Interactions And SucessionLinda Craun
 

En vedette (20)

This is-it
This is-itThis is-it
This is-it
 
I love data science
I love data scienceI love data science
I love data science
 
ABONO ORGÁNICO. Lic Javier Cucaita
ABONO ORGÁNICO. Lic Javier CucaitaABONO ORGÁNICO. Lic Javier Cucaita
ABONO ORGÁNICO. Lic Javier Cucaita
 
Daily Newsletter: 14th January, 2011
Daily Newsletter: 14th January, 2011Daily Newsletter: 14th January, 2011
Daily Newsletter: 14th January, 2011
 
Workshop #12: Research toolbox: Exploring innovation opportunities, emotion a...
Workshop #12: Research toolbox: Exploring innovation opportunities, emotion a...Workshop #12: Research toolbox: Exploring innovation opportunities, emotion a...
Workshop #12: Research toolbox: Exploring innovation opportunities, emotion a...
 
что такое информация
что такое информациячто такое информация
что такое информация
 
The Play Ethic: lessons from play in an adverse economic climate
The Play Ethic: lessons from play in an adverse economic climateThe Play Ethic: lessons from play in an adverse economic climate
The Play Ethic: lessons from play in an adverse economic climate
 
DHKS PRESETATION
DHKS PRESETATIONDHKS PRESETATION
DHKS PRESETATION
 
Seth Godin's Presentation Hierarchy
Seth Godin's Presentation HierarchySeth Godin's Presentation Hierarchy
Seth Godin's Presentation Hierarchy
 
LeadingPlus Electronic Co.,Ltd
LeadingPlus Electronic Co.,LtdLeadingPlus Electronic Co.,Ltd
LeadingPlus Electronic Co.,Ltd
 
25 6.1 pug_tresc
25 6.1 pug_tresc25 6.1 pug_tresc
25 6.1 pug_tresc
 
Journal Reliability
Journal Reliability Journal Reliability
Journal Reliability
 
The role of Community Knowledge Centres in enhancing agricultural and communi...
The role of Community Knowledge Centres in enhancing agricultural and communi...The role of Community Knowledge Centres in enhancing agricultural and communi...
The role of Community Knowledge Centres in enhancing agricultural and communi...
 
Tanya Kearin Resume
Tanya Kearin ResumeTanya Kearin Resume
Tanya Kearin Resume
 
W. Bruce C Bailey: The Art of Art Collecting
W. Bruce C Bailey: The Art of Art CollectingW. Bruce C Bailey: The Art of Art Collecting
W. Bruce C Bailey: The Art of Art Collecting
 
CLASES DE COMPUTACION
CLASES DE COMPUTACIONCLASES DE COMPUTACION
CLASES DE COMPUTACION
 
TUTORIAL_JUEGO_MEMOTEST_2013
TUTORIAL_JUEGO_MEMOTEST_2013TUTORIAL_JUEGO_MEMOTEST_2013
TUTORIAL_JUEGO_MEMOTEST_2013
 
Cchandler portfolio feb_09_16
Cchandler portfolio feb_09_16Cchandler portfolio feb_09_16
Cchandler portfolio feb_09_16
 
Daily Newsletter: 11th January, 2011
Daily Newsletter: 11th January, 2011Daily Newsletter: 11th January, 2011
Daily Newsletter: 11th January, 2011
 
Community Interactions And Sucession
Community Interactions And SucessionCommunity Interactions And Sucession
Community Interactions And Sucession
 

Similaire à 15.simulated anneling

Physics 498 SQD -- Lecture 3 -- Models and theories of superconductivity FINA...
Physics 498 SQD -- Lecture 3 -- Models and theories of superconductivity FINA...Physics 498 SQD -- Lecture 3 -- Models and theories of superconductivity FINA...
Physics 498 SQD -- Lecture 3 -- Models and theories of superconductivity FINA...RohitNukte
 
ep ppt of it .pptx
ep ppt of it .pptxep ppt of it .pptx
ep ppt of it .pptxbsabjdsv
 
Ising.ppt.pdf
Ising.ppt.pdfIsing.ppt.pdf
Ising.ppt.pdfHazelAli1
 
Monte Carlo Simulation Methods
Monte Carlo Simulation MethodsMonte Carlo Simulation Methods
Monte Carlo Simulation Methodsioneec
 
Exp 2 (1)2. To plot Swing Curve for one Machine System
Exp 2 (1)2.	To plot Swing Curve for one Machine SystemExp 2 (1)2.	To plot Swing Curve for one Machine System
Exp 2 (1)2. To plot Swing Curve for one Machine SystemShweta Yadav
 
Transfer Function Cse ppt
Transfer Function Cse pptTransfer Function Cse ppt
Transfer Function Cse pptsanjaytron
 
Hidden Markov Models.pptx
Hidden Markov Models.pptxHidden Markov Models.pptx
Hidden Markov Models.pptxFahadSherwani6
 
Computation of electromagnetic_fields_scattered_from_dielectric_objects_of_un...
Computation of electromagnetic_fields_scattered_from_dielectric_objects_of_un...Computation of electromagnetic_fields_scattered_from_dielectric_objects_of_un...
Computation of electromagnetic_fields_scattered_from_dielectric_objects_of_un...Alexander Litvinenko
 

Similaire à 15.simulated anneling (20)

NLP_KASHK:Markov Models
NLP_KASHK:Markov ModelsNLP_KASHK:Markov Models
NLP_KASHK:Markov Models
 
Control Systems Assignment Help
Control Systems Assignment HelpControl Systems Assignment Help
Control Systems Assignment Help
 
Ch03 9
Ch03 9Ch03 9
Ch03 9
 
Physics 498 SQD -- Lecture 3 -- Models and theories of superconductivity FINA...
Physics 498 SQD -- Lecture 3 -- Models and theories of superconductivity FINA...Physics 498 SQD -- Lecture 3 -- Models and theories of superconductivity FINA...
Physics 498 SQD -- Lecture 3 -- Models and theories of superconductivity FINA...
 
3D ISING MODEL
3D ISING MODEL3D ISING MODEL
3D ISING MODEL
 
ep ppt of it .pptx
ep ppt of it .pptxep ppt of it .pptx
ep ppt of it .pptx
 
Ising.ppt.pdf
Ising.ppt.pdfIsing.ppt.pdf
Ising.ppt.pdf
 
sbs.pdf
sbs.pdfsbs.pdf
sbs.pdf
 
Monte Carlo Simulation Methods
Monte Carlo Simulation MethodsMonte Carlo Simulation Methods
Monte Carlo Simulation Methods
 
Exp 2 (1)2. To plot Swing Curve for one Machine System
Exp 2 (1)2.	To plot Swing Curve for one Machine SystemExp 2 (1)2.	To plot Swing Curve for one Machine System
Exp 2 (1)2. To plot Swing Curve for one Machine System
 
Dynamics
DynamicsDynamics
Dynamics
 
Hidden Markov Model
Hidden Markov Model Hidden Markov Model
Hidden Markov Model
 
Kondo Effect.pptx
Kondo Effect.pptxKondo Effect.pptx
Kondo Effect.pptx
 
Transfer Function Cse ppt
Transfer Function Cse pptTransfer Function Cse ppt
Transfer Function Cse ppt
 
Quantum Assignment Help
Quantum Assignment HelpQuantum Assignment Help
Quantum Assignment Help
 
Quantum state
Quantum stateQuantum state
Quantum state
 
Hidden Markov Models
Hidden Markov ModelsHidden Markov Models
Hidden Markov Models
 
Hidden Markov Models.pptx
Hidden Markov Models.pptxHidden Markov Models.pptx
Hidden Markov Models.pptx
 
Computation of electromagnetic_fields_scattered_from_dielectric_objects_of_un...
Computation of electromagnetic_fields_scattered_from_dielectric_objects_of_un...Computation of electromagnetic_fields_scattered_from_dielectric_objects_of_un...
Computation of electromagnetic_fields_scattered_from_dielectric_objects_of_un...
 
By BIRASA FABRICE
By BIRASA FABRICEBy BIRASA FABRICE
By BIRASA FABRICE
 

Plus de Abhijeet Kadam (20)

27.docking protein-protein and protein-ligand
27.docking protein-protein and protein-ligand27.docking protein-protein and protein-ligand
27.docking protein-protein and protein-ligand
 
26.docking
26.docking26.docking
26.docking
 
25.qsar
25.qsar25.qsar
25.qsar
 
24.prodrug
24.prodrug24.prodrug
24.prodrug
 
23.optimizing access to target
23.optimizing access to target23.optimizing access to target
23.optimizing access to target
 
22.pharmacophore
22.pharmacophore22.pharmacophore
22.pharmacophore
 
21.umls
21.umls21.umls
21.umls
 
20.drug discovery
20.drug discovery20.drug discovery
20.drug discovery
 
19.cobra
19.cobra19.cobra
19.cobra
 
18.xml
18.xml18.xml
18.xml
 
17.interoperability
17.interoperability17.interoperability
17.interoperability
 
14.machine learning
14.machine learning14.machine learning
14.machine learning
 
13.cartesian coordinates
13.cartesian coordinates13.cartesian coordinates
13.cartesian coordinates
 
12.protein folding
12.protein folding12.protein folding
12.protein folding
 
11.ramachandran plot
11.ramachandran plot11.ramachandran plot
11.ramachandran plot
 
10.torsion angles
10.torsion angles10.torsion angles
10.torsion angles
 
9.protein ligand interactions2
9.protein ligand interactions29.protein ligand interactions2
9.protein ligand interactions2
 
8.protein ligand interactions
8.protein ligand interactions8.protein ligand interactions
8.protein ligand interactions
 
7.local and global minima
7.local and global minima7.local and global minima
7.local and global minima
 
6.ab initio qm
6.ab initio qm6.ab initio qm
6.ab initio qm
 

Dernier

FBI Profiling - Forensic Psychology.pptx
FBI Profiling - Forensic Psychology.pptxFBI Profiling - Forensic Psychology.pptx
FBI Profiling - Forensic Psychology.pptxPayal Shrivastava
 
Loudspeaker- direct radiating type and horn type.pptx
Loudspeaker- direct radiating type and horn type.pptxLoudspeaker- direct radiating type and horn type.pptx
Loudspeaker- direct radiating type and horn type.pptxpriyankatabhane
 
Science (Communication) and Wikipedia - Potentials and Pitfalls
Science (Communication) and Wikipedia - Potentials and PitfallsScience (Communication) and Wikipedia - Potentials and Pitfalls
Science (Communication) and Wikipedia - Potentials and PitfallsDobusch Leonhard
 
lect1 introduction.pptx microbiology ppt
lect1 introduction.pptx microbiology pptlect1 introduction.pptx microbiology ppt
lect1 introduction.pptx microbiology pptzbyb6vmmsd
 
Environmental Acoustics- Speech interference level, acoustics calibrator.pptx
Environmental Acoustics- Speech interference level, acoustics calibrator.pptxEnvironmental Acoustics- Speech interference level, acoustics calibrator.pptx
Environmental Acoustics- Speech interference level, acoustics calibrator.pptxpriyankatabhane
 
Introduction of Organ-On-A-Chip - Creative Biolabs
Introduction of Organ-On-A-Chip - Creative BiolabsIntroduction of Organ-On-A-Chip - Creative Biolabs
Introduction of Organ-On-A-Chip - Creative BiolabsCreative-Biolabs
 
Speed Breeding in Vegetable Crops- innovative approach for present era of cro...
Speed Breeding in Vegetable Crops- innovative approach for present era of cro...Speed Breeding in Vegetable Crops- innovative approach for present era of cro...
Speed Breeding in Vegetable Crops- innovative approach for present era of cro...jana861314
 
Charateristics of the Angara-A5 spacecraft launched from the Vostochny Cosmod...
Charateristics of the Angara-A5 spacecraft launched from the Vostochny Cosmod...Charateristics of the Angara-A5 spacecraft launched from the Vostochny Cosmod...
Charateristics of the Angara-A5 spacecraft launched from the Vostochny Cosmod...Christina Parmionova
 
Harry Coumnas Thinks That Human Teleportation May Ensure Humanity's Survival
Harry Coumnas Thinks That Human Teleportation May Ensure Humanity's SurvivalHarry Coumnas Thinks That Human Teleportation May Ensure Humanity's Survival
Harry Coumnas Thinks That Human Teleportation May Ensure Humanity's Survivalkevin8smith
 
Unit-V-Introduction to Data Mining.pptx
Unit-V-Introduction to  Data Mining.pptxUnit-V-Introduction to  Data Mining.pptx
Unit-V-Introduction to Data Mining.pptxHarsha Patel
 
Timeless Cosmology: Towards a Geometric Origin of Cosmological Correlations
Timeless Cosmology: Towards a Geometric Origin of Cosmological CorrelationsTimeless Cosmology: Towards a Geometric Origin of Cosmological Correlations
Timeless Cosmology: Towards a Geometric Origin of Cosmological CorrelationsDanielBaumann11
 
Think Science: What Are Eclipses (101), by Craig Bobchin
Think Science: What Are Eclipses (101), by Craig BobchinThink Science: What Are Eclipses (101), by Craig Bobchin
Think Science: What Are Eclipses (101), by Craig BobchinNathan Cone
 
Production technology of Brinjal -Solanum melongena
Production technology of Brinjal -Solanum melongenaProduction technology of Brinjal -Solanum melongena
Production technology of Brinjal -Solanum melongenajana861314
 
Pests of Sunflower_Binomics_Identification_Dr.UPR
Pests of Sunflower_Binomics_Identification_Dr.UPRPests of Sunflower_Binomics_Identification_Dr.UPR
Pests of Sunflower_Binomics_Identification_Dr.UPRPirithiRaju
 
Interpreting SDSS extragalactic data in the era of JWST
Interpreting SDSS extragalactic data in the era of JWSTInterpreting SDSS extragalactic data in the era of JWST
Interpreting SDSS extragalactic data in the era of JWSTAlexander F. Mayer
 
Combining Asynchronous Task Parallelism and Intel SGX for Secure Deep Learning
Combining Asynchronous Task Parallelism and Intel SGX for Secure Deep LearningCombining Asynchronous Task Parallelism and Intel SGX for Secure Deep Learning
Combining Asynchronous Task Parallelism and Intel SGX for Secure Deep Learningvschiavoni
 
Environmental acoustics- noise criteria.pptx
Environmental acoustics- noise criteria.pptxEnvironmental acoustics- noise criteria.pptx
Environmental acoustics- noise criteria.pptxpriyankatabhane
 
DNA isolation molecular biology practical.pptx
DNA isolation molecular biology practical.pptxDNA isolation molecular biology practical.pptx
DNA isolation molecular biology practical.pptxGiDMOh
 

Dernier (20)

FBI Profiling - Forensic Psychology.pptx
FBI Profiling - Forensic Psychology.pptxFBI Profiling - Forensic Psychology.pptx
FBI Profiling - Forensic Psychology.pptx
 
Loudspeaker- direct radiating type and horn type.pptx
Loudspeaker- direct radiating type and horn type.pptxLoudspeaker- direct radiating type and horn type.pptx
Loudspeaker- direct radiating type and horn type.pptx
 
Science (Communication) and Wikipedia - Potentials and Pitfalls
Science (Communication) and Wikipedia - Potentials and PitfallsScience (Communication) and Wikipedia - Potentials and Pitfalls
Science (Communication) and Wikipedia - Potentials and Pitfalls
 
lect1 introduction.pptx microbiology ppt
lect1 introduction.pptx microbiology pptlect1 introduction.pptx microbiology ppt
lect1 introduction.pptx microbiology ppt
 
Environmental Acoustics- Speech interference level, acoustics calibrator.pptx
Environmental Acoustics- Speech interference level, acoustics calibrator.pptxEnvironmental Acoustics- Speech interference level, acoustics calibrator.pptx
Environmental Acoustics- Speech interference level, acoustics calibrator.pptx
 
PLASMODIUM. PPTX
PLASMODIUM. PPTXPLASMODIUM. PPTX
PLASMODIUM. PPTX
 
Introduction of Organ-On-A-Chip - Creative Biolabs
Introduction of Organ-On-A-Chip - Creative BiolabsIntroduction of Organ-On-A-Chip - Creative Biolabs
Introduction of Organ-On-A-Chip - Creative Biolabs
 
Speed Breeding in Vegetable Crops- innovative approach for present era of cro...
Speed Breeding in Vegetable Crops- innovative approach for present era of cro...Speed Breeding in Vegetable Crops- innovative approach for present era of cro...
Speed Breeding in Vegetable Crops- innovative approach for present era of cro...
 
Charateristics of the Angara-A5 spacecraft launched from the Vostochny Cosmod...
Charateristics of the Angara-A5 spacecraft launched from the Vostochny Cosmod...Charateristics of the Angara-A5 spacecraft launched from the Vostochny Cosmod...
Charateristics of the Angara-A5 spacecraft launched from the Vostochny Cosmod...
 
Harry Coumnas Thinks That Human Teleportation May Ensure Humanity's Survival
Harry Coumnas Thinks That Human Teleportation May Ensure Humanity's SurvivalHarry Coumnas Thinks That Human Teleportation May Ensure Humanity's Survival
Harry Coumnas Thinks That Human Teleportation May Ensure Humanity's Survival
 
Unit-V-Introduction to Data Mining.pptx
Unit-V-Introduction to  Data Mining.pptxUnit-V-Introduction to  Data Mining.pptx
Unit-V-Introduction to Data Mining.pptx
 
Timeless Cosmology: Towards a Geometric Origin of Cosmological Correlations
Timeless Cosmology: Towards a Geometric Origin of Cosmological CorrelationsTimeless Cosmology: Towards a Geometric Origin of Cosmological Correlations
Timeless Cosmology: Towards a Geometric Origin of Cosmological Correlations
 
Think Science: What Are Eclipses (101), by Craig Bobchin
Think Science: What Are Eclipses (101), by Craig BobchinThink Science: What Are Eclipses (101), by Craig Bobchin
Think Science: What Are Eclipses (101), by Craig Bobchin
 
Production technology of Brinjal -Solanum melongena
Production technology of Brinjal -Solanum melongenaProduction technology of Brinjal -Solanum melongena
Production technology of Brinjal -Solanum melongena
 
Pests of Sunflower_Binomics_Identification_Dr.UPR
Pests of Sunflower_Binomics_Identification_Dr.UPRPests of Sunflower_Binomics_Identification_Dr.UPR
Pests of Sunflower_Binomics_Identification_Dr.UPR
 
Bioenergetics and the role of ATP to drive the beats of life.
Bioenergetics and the role of ATP to drive the beats of life.Bioenergetics and the role of ATP to drive the beats of life.
Bioenergetics and the role of ATP to drive the beats of life.
 
Interpreting SDSS extragalactic data in the era of JWST
Interpreting SDSS extragalactic data in the era of JWSTInterpreting SDSS extragalactic data in the era of JWST
Interpreting SDSS extragalactic data in the era of JWST
 
Combining Asynchronous Task Parallelism and Intel SGX for Secure Deep Learning
Combining Asynchronous Task Parallelism and Intel SGX for Secure Deep LearningCombining Asynchronous Task Parallelism and Intel SGX for Secure Deep Learning
Combining Asynchronous Task Parallelism and Intel SGX for Secure Deep Learning
 
Environmental acoustics- noise criteria.pptx
Environmental acoustics- noise criteria.pptxEnvironmental acoustics- noise criteria.pptx
Environmental acoustics- noise criteria.pptx
 
DNA isolation molecular biology practical.pptx
DNA isolation molecular biology practical.pptxDNA isolation molecular biology practical.pptx
DNA isolation molecular biology practical.pptx
 

15.simulated anneling

  • 2. Intro ● Annealing – cooling temperature in metallargy ● An optimization algo inspired by Stastical Mechanics ● Combination of – 1) MCMC Algo 2) Metropilos Algo
  • 3. MCMC Algo ● Marcov Chain Monte Carlo ● Involves a Stochastic element (random) ● This helps computer to take random decisions ● Depends on state and transition between 2 states in MM
  • 4. Metropolis Algo ● Randomly generates perturbations of current state (approx soln) ● Accepts or rejects them based on how the probability of state is effected ● Like a schedule of lovering temperature
  • 5. Example – Minimizing a function ● F = (x1.....xn) and f>=0 ● If f – represemtsenergy of a stastical mechanical system ● We have states S=(x1....xn) ● Hence the probability of state S at temperature T is given by ● p(S) = Boltzmann-gibbs distribution
  • 6. ● If there are m states ● Limits P(S) = 1/m (is Sis at ground state) t->0 = 0 (if otherwise) ● Hence we could stimulate the system at temperature near 0, we get ground state
  • 7. ● But MCMC and Metropolis fail to generate Minima ● Because, movement in state space is inhibited by regions of low probability and by high energy barriers ● Simulated Anneling overcomes this problem
  • 8. ● Starts at high temp and progresses to lower temp ● Annealing Schedule is given By - ● ● ● Hence as algo proceeds – inc in energy is less likely ● And hence minima of energy could be acheived
  • 9. Applications ● Molecular Dynamics ● PL docing ● Homology Modelling
  • 10. Applications ● Molecular Dynamics ● PL docing ● Homology Modelling