Hematology Course: an overview of Clinical Hematology Dr. Ahmed Elshebiny , MD Lecturer of Internal Medicine Faculty of Medicine, Menoufyia University Former Clinical Research Fellow, Joslin Diabetes Center, Harvard University

Structure and Function The blood and bone marrow

Blood is continuously renewed

The Bone Marrow is the blood Factory May be exposed to damage or failure

Fetal and neonatal hemoglobins

HB and MCV values with age & sex

Aplastic Anemia

Bone marrow aspiration and biopsy

Bone marrow aspiration

P.N.H

Hematology Course (2): Clinical Hematology Abnormal Blood count

Hematology Course (3): Clinical Hematology Anemia : a clinical approach!

Anemia is operationally defined as a reduction in one or more of the major RBC measurements: hemoglobin concentration, hematocrit, or RBC count Keep in mind these are all concentration measures … most accurately measured by obtaining a RBC mass via isotopic dilution methods. Definition:

Normal blood film

Morphological approach

Reticulocytes

Iron difficiency anemia Thalassemia

Thalassemia

Sickle cell anemia

Spherocytosis

Hemolytic anemia

Macrocytic anemia

B 12 and folate deficiency

THANK YOU