Amazon EC2 Fleet makes it easy to optimize compute performance and cost by blending Amazon EC2 Spot, On-Demand, and Reserved Instances purchasing models. In this session, we learn how to use the power of Amazon EC2 Fleet with AWS services such as AWS Auto Scaling, Amazon Elastic Container Service (Amazon ECS), Amazon Elastic Container Service for Kubernetes (Amazon EKS), Amazon EMR, AWS Batch, AWS Thinkbox Deadline, and AWS OpsWorks to programmatically optimize costs while maintaining high performance and availability. We also discuss cost-optimization patterns for workloads such as containers, web services, CI/CD, and big data.