In wireless communications and data acquisition systems, there is more to consider when designing and implementing a complete solution beyond simply physically connecting a high speed analog module to an FPGA platform. Available hardware description language (HDL) components and software are critical to establishing an interface, which is necessary for practical system integration. This session starts with a top-level overview of various physical interfaces that are typically used and provides an in-depth focus on high speed serial JESD204B. Prototype HDL used for these types of boards is covered, along with the specific board components and how they are used to interface to high speed ADCs and DACs. Linux device drivers for the HDL components, as well as for the ADI components, are presented. This includes a short introduction into the Industrial I/O (IIO) framework, the benefits it offers, and how it can be used in end designs.