Credits to Ma'am Evangeline Teruel

3. Ex:
Neomycin SO4
 streptomycin SO4
polymycin A and B SO4
colistin SO4
kanamycin SO4.

4. MAO (monoamine
oxidase) inhibitors

5. thiazides

6. Reserpine
Hydralazine
methyldopa

7. Heparin
Coumadin

9. cortisone

10. GA
1. CARDIAC
ARREST

11. 2. RESPIRATORY DEPRESSION
a. Excessive mucus
b. CNS depression
c. Bronchospasm/ laryngospasm

12. 3. HYPOTENSION
AND SHOCK

13. 4. LOSS OF
PROTECTIVE
RESPONSE TO
PAIN

14. 5. VOMITING
AND
ASPIRATIONS

15. 6.

16. 7. Malignant
hyperthermia:
possible
treatment with
dantrolene

17.  Establish an open airway.
 Give oxygen.
 Notify the surgeon.
 Fast-acting barbiturate is usual treatment.
 If toxic reaction is untreated,
unconsciousness, hypotension, apnea,
cardiac arrest, and death may result.

18. COMPLICATIONS

19. 1. Anaphylaxis
 Immunologic sensitization
 methylparaben
 Overdosage
 Hazardous site:
▪ Vascular: Tracheobronchial mucosa
▪ Tissue: head, neck, paravertebral.

20. 1.HYPOTENSION

21. PREVENTION:
 Infuse 500-800 mL of IV if not
prone to CHF
INTERVENTION:
 Oxygen administration
 Vasoconstrictive drugs
 Trendelenburg position 10-20
mins after induction

22. PREVENTION:
 Avoid extreme trendelenburg
position before level of
anesthesia sets
INTERVENTION:
 Artificial airway

23. 2.NAUSEA AND VOMITING
INTERVENTION:
 Oxygen administration
 Give ephedrine, anti-
emetics
 IVF

24. 3. HEADACHE – excessive
loss of CSF due to:
a.Loss of large spinal fluid
b.Poor hydration

25. PREVENTION:
 Use of small needle
 Administer IV before and after
induction
 Keep well hydrated to aid in
spinal fluid replacement.
 inject client blood to plug the
hole (10cc)
 Flat on bed for 6 to 8 hours

26. INTERVENTION:
Apply tight abdominal
binder
IV administration
Analgesic

27. 4.Overdosage

28. 5. RESPIRATORY PARALYSIS
– happens when drug
reaches upper thoracic and
cervical cord in large
amount or in heavy doses

29. 6. Neurological Complication
- maybe due to:
a. unsterile needle, syringes or
anesthetic agent
b. per-existing disease of CNS
c. transient response to
anesthetics
d. position during surgery

30. supportive care for transient
forms
 antibiotic and steroid
therapy
 rehabilitation for
permanent paralysis

31. The side effects of local anesthetics
 Local effects- local irritation and skin
breakdown
 CNS effects if systemic absorption occurs-
headache, restlessness, anxiety, dizziness,
tremors and blurred vision.
 GI system- nausea, vomiting
 Cardio- arrhythmias, peripheral vasodilation,
myocardial depression, and rarely, cardiac
arrest